keyword
https://read.qxmd.com/read/38530574/transitional-pain-service-an-update
#1
REVIEW
Ruben Klimke, Alexander Ott, Carolina S Romero, Andrea Berendes, Richard D Urman, Markus M Luedi, Vighnesh Ashok
PURPOSE OF REVIEW: Chronic Postsurgical Pain (CPSP) and the risk for long-term opioid dependency are known complications following major surgery. The idea of Transitional Pain Service (TPS) has been introduced as an interdisciplinary setting to manage pain in the perioperative continuum. We expand on the basic framework and principles of TPS and summarize the current evidence of the TPS and possible interventions to adress postoperative pain. Areas of future work in TPS-related research are discussed...
March 26, 2024: Current Pain and Headache Reports
https://read.qxmd.com/read/38518669/effects-of-puerarin-as-a-feed-additive-on-the-laying-performance-egg-quality-endocrine-hormones-antioxidant-capacity-and-intestinal-morphology-of-aged-laying-hens
#2
JOURNAL ARTICLE
Xubin Du, Dong Zhao, Huifang Pian, Yan Li, Xinyue Wu, Fei Liu, Debing Yu
The aim of this study was to investigate the effects of puerarin (Pue), a phytoestrogen, on the production performance, egg quality, endocrine hormones, antioxidant capacity, and intestinal morphology in aged laying hens. A total of 180 Hy-Line Brown hens aged 480 d were randomly divided into 4 groups (n = 45 per group) and fed 0, 200, 400, and 800 mg/kg of Pue (Con, L-Pue, M-Pue, and H-Pue, respectively) during a 42-d experiment. Compared with the Con treatment, supplementation with H-Pue improved laying performance and egg quality by significantly increasing egg production, average egg weight, albumen height, yolk weight, and Haugh unit (P < 0...
January 9, 2024: Poultry Science
https://read.qxmd.com/read/38514006/ptgs2-a-potential-immune-regulator-and-therapeutic-target-for-chronic-spontaneous-urticaria
#3
JOURNAL ARTICLE
Yihui Chen, Xingxing Jian, Lei Zhu, Pian Yu, Xiaoqing Yi, Qiaozhi Cao, Jiayi Wang, Feng Xiong, Jie Li
AIMS: Chronic spontaneous urticaria (CSU) is a common and debilitating skin disease that is difficult to control with existing treatments, and the pathogenesis of CSU has not been fully revealed. The aim of this study was to explore the underlying mechanisms of CSU and identify potential treatments. MATERIALS AND METHODS: Microarray datasets of CSU were obtained from Gene Expression Omnibus database. Differentially expressed genes between skin lesions of CSU and normal controls (LNS-DEGs) were identified, and the enrichment analyses of LNS-DEGs were performed...
March 19, 2024: Life Sciences
https://read.qxmd.com/read/38455959/total-cucurbitacins-from-herpetospermum-pedunculosum-pericarp-do-better-than-hu-lu-su-pian-hlsp-in-its-safety-and-hepatoprotective-efficacy
#4
JOURNAL ARTICLE
Wen-Ya Liu, Di Xu, Zi-Yun Hu, Hui-Hui Meng, Qi Zheng, Feng-Ye Wu, Xin Feng, Jun-Song Wang
The pericarp of Herpetospermum pedunculosum (HPP) has traditionally been used for treating jaundice and hepatitis. However, the specific hepatoprotective components and their safety/efficacy profiles remain unclear. This study aimed to characterize the total cucurbitacins (TCs) extracted from HPP and evaluate their hepatoprotective potential. As a reference, Hu-lu-su-pian (HLSP), a known hepatoprotective drug containing cucurbitacins, was used for comparison of chemical composition, effects, and safety. Molecular networking based on UHPLC-MS/MS identified cucurbitacin B, isocucurbitacin B, and cucurbitacin E as the major components in TCs, comprising 70...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38420029/a-retrospective-study-of-variations-in-the-kinds-of-diseases-discharged-from-the-department-of-infectious-diseases-of-a-large-general-hospital-in-central-china-during-2013-2019
#5
JOURNAL ARTICLE
Pian Ye, Lei Zhao, Ran Pang, Xin Zheng
OBJECTIVE: To analyze the changing trend of the absolute number and constituent ratio of various in-patient diseases in the Department of Infectious Diseases of a large general hospital in Central China during 2013-2019. METHODS: A retrospective study was conducted to analyze the diagnostic data of discharged patients for seven consecutive years, from 2013 to 2019. The first discharge diagnosis is used as the basis for the disease classification. The absolute number, constituent ratio, and changing trend of major diseases in hepatobiliary diseases and infectious diseases were analyzed...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38369679/cytotoxicity-of-bismuth-iii-dithiocarbamate-derivatives-by-promoting-a-mitochondrial-dependent-apoptotic-pathway-and-suppressing-mcf-7-breast-adenocarcinoma-cell-invasion
#6
JOURNAL ARTICLE
Pit Foong Chan, Kok Pian Ang, Roslida Abd Hamid
We previously reported that the bismuth(III) dithiocarbamate derivative, bismuth diethyldithiocarbamate (1) exhibited greater cytotoxicity while inducing apoptosis via the intrinsic pathway in MCF-7 cells. We further evaluated the other bismuth(III) dithiocarbamate derivatives, Bi[S2 CNR]3 , with R = (CH2 CH2 OH)(i Pr), (CH2 )4 , and (CH2 CH2 OH)(CH3 ), denoted as 2, 3, and 4, respectively, in the same MCF-7 cell line. 2-4 were found to exhibit IC50 values of 10.33 ± 0.06 µM, 1...
February 18, 2024: Journal of Biological Inorganic Chemistry: JBIC
https://read.qxmd.com/read/38358379/removal-of-expression-of-concern-sodium-butyrate-ameliorated-diabetic-nephropathy-associated-tubulointerstitial-inflammation-by-modulating-tight-junction-of-renal-tubular-epithelial-cells
#7
COMMENT
Tingting Yang, Lin Lia, Cai Heng, Pian Sha, Yiying Wang, Jiaming Shen, Zhenzhou Jiang, Sitong Qian, Chujing Wei, Hao Yang, Xia Zhu, Tao Wang, Mengying Wu, Jianyun Wang, Qian Lu, Xiaoxing Yin
Removal of Expression of Concern for 'Sodium butyrate ameliorated diabetic nephropathy-associated tubulointerstitial inflammation by modulating tight junction of renal tubular epithelial cells' by Tingting Yang et al. , Food Funct. , 2022, Accepted Manuscript, https://doi.org/10.1039/D2FO00940D.
February 15, 2024: Food & Function
https://read.qxmd.com/read/38358014/sodium-butyrate-ameliorated-diabetic-nephropathy-associated-tubulointerstitial-inflammation-by-modulating-the-tight-junctions-of-renal-tubular-epithelial-cells
#8
JOURNAL ARTICLE
Tingting Yang, Lin Li, Cai Heng, Pian Sha, Yiying Wang, Jiaming Shen, Zhenzhou Jiang, Sitong Qian, Chujing Wei, Hao Yang, Xia Zhu, Tao Wang, Mengying Wu, Jianyun Wang, Qian Lu, Xiaoxing Yin
As one of the most significant pathological changes of diabetic nephropathy (DN), tubulointerstitial fibrosis (TIF) had a close relationship with tubulointerstitial inflammation (TI), and the occurrence of TI could have resulted from the disrupted tight junctions (TJs) of renal tubular epithelial cells (RTECs). Studies have demonstrated that sodium butyrate (NaB), a typical short chain fatty acid (SCFA), played an important regulatory role in intestinal TJs and inflammation. In this study, our in vivo and in vitro results showed that accompanied by TI, renal tubular TJs were gradually disrupted in the process of DN-related TIF...
February 15, 2024: Food & Function
https://read.qxmd.com/read/38355813/development-and-validation-of-a-prediction-model-for-consistency-of-pituitary-adenoma-the-pitcon-score
#9
JOURNAL ARTICLE
Alberto Acitores Cancela, Víctor Rodríguez Berrocal, Hector Pian Arias, Juan José Díez Gómez, Pedro Iglesias Lozano
PURPOSE: Pituitary adenomas (PAs) usually have a soft consistency, facilitating gross total resection. However, 5-13% of PAs with fibrous consistency are challenging to remove entirely and are accompanied by greater morbimortality. This study aims to identify the clinical and radiological characteristics that correlate with PA fibrous consistency preoperatively. A simple scoring system has been proposed to predict incidence of fibrous PAs. MATERIALS AND METHODS: Consecutive interventions (226) were analyzed, all performed through an endoscopic endonasal transsphenoidal approach...
February 15, 2024: Acta Neurochirurgica
https://read.qxmd.com/read/38342223/surgery-for-adrenal-metastasis-surgical-outcomes-and-prognostic-factors-for-long-term-survival
#10
JOURNAL ARTICLE
César Mínguez Ojeda, Victoria Gómez Dos Santos, Javier Ÿlvaro Lorca, Ignacio Ruz-Caracuel, Héctor Pian, Alfonso Sanjuanbenito Dehesa, Elvira Gutiérrez Gutiérrez, Juan Luis Sanz Miguelañez, Bernabé Pozo Mengual, Francisco Javier Burgos Revilla, Marta Araujo-Castro
PURPOSE: To analyze surgical outcomes and predictive factors for long-term overall and disease-specific survival in patients undergoing surgical resection of adrenal metastasis. METHODS: A multicenter retrospective study included patients who underwent adrenalectomy for adrenal metastasis in two Spanish hospitals between 2005 and 2021. Clinical variables associated with surgical complications and survival during follow-up were analyzed. RESULTS: Thirty-three patients were included...
February 9, 2024: Annales D'endocrinologie
https://read.qxmd.com/read/38308791/cumulative-genetic-scores-interact-with-maternal-and-paternal-parenting-in-predicting-parent-adolescent-cohesion-and-conflict
#11
JOURNAL ARTICLE
Pian Chen, Shan Sun, Yang Yang, Aodi Huang, Hongmei Zhang, Meiping Wang
Previous research concerning the interplay between genetics and parenting in the development of the parent-child relationship during adolescence has been extremely scarce, predominantly adopting single-gene designs. This limited body of work has largely overlooked the distinct effects of maternal and paternal roles, as well as potential gender differences. Additionally, existing gene-by-environment (G × E) studies have mainly concentrated on adverse environmental factors and associated negative outcomes, somewhat neglecting positive environments and outcomes...
February 3, 2024: Journal of Youth and Adolescence
https://read.qxmd.com/read/38300921/psychometric-properties-of-the-brazilian-portuguese-flow-state-scale-short-fss-br-s
#12
JOURNAL ARTICLE
Ig Ibert Bittencourt, Leogildo Freires, Yu Lu, Geiser Chalco Challco, Sheyla Fernandes, Jorge Coelho, Julio Costa, Yang Pian, Alexandre Marinho, Seiji Isotani
"Flow experience" is a term used to describe the state of being fully immersed in what you are doing. The Flow State Scale (FSS-2) was developed to assess how people feel when they are in the flow state while participating in certain sports activities. The goal of this study was to obtain a short adapted version of the FSS-2 for the Brazilian-Portuguese language and for general activities (FSS-BR-S). To do this, we translated it both ways (forwards and backwards) and verified that the translation was accurate...
2024: PloS One
https://read.qxmd.com/read/38289863/gender-and-pathways-to-leadership-in-academic-anesthesiology-a-qualitative-content-analysis-of-us-chairpersons-curricula-vitae
#13
JOURNAL ARTICLE
Meghan B Lane-Fall, Maya J Hastie, Melanie Kleid, Varun Yarabarla, Andrea N Miltiades, Jeanine P Wiener-Kronish, May C Pian-Smith
BACKGROUND: Women are underrepresented in medicine and academic anesthesiology, and especially in leadership positions. We sought to characterize career achievement milestones of female versus male academic anesthesiology chairs to understand possible gender-related differences in pathways to leadership. METHODS: We conducted a retrospective observational cross-sectional analysis. In November 2019, curricula vitae (CVs) were requested from then-current members of the US Association of Academic Anesthesiology Chairs...
January 30, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38254942/transcriptome-profiling-identifies-differentially-expressed-genes-in-skeletal-muscle-development-in-native-chinese-ducks
#14
JOURNAL ARTICLE
Yuchen Zhang, Yinglin Lu, Minli Yu, Jin Wang, Xubin Du, Dong Zhao, Huifang Pian, Zongliang He, Guansuo Wu, Shiwei Li, Sike Wang, Debing Yu
China boasts a rich diversity of indigenous duck species, some of which exhibit desirable economic traits. Here, we generated transcriptome sequencing datasets of breast muscle tissue samples from 1D of four groups: Pekin duck pure breeding group (P), Jinling White duck breeding group (J), P ♂ × J ♀ orthogonal group (PJ) and J ♂ × P ♀ reciprocal-cross group (JP) ( n = 3), chosen based on the distinctive characteristics of duck muscle development during the embryonic period...
December 28, 2023: Genes
https://read.qxmd.com/read/38250308/advances-in-targeted-drug-resistance-associated-with-dysregulation-of-lipid-metabolism-in-hepatocellular-carcinoma
#15
REVIEW
Xiaoju Huang, Mengmeng Wang, Dan Zhang, Chen Zhang, Pian Liu
Hepatocellular carcinoma is the prevailing malignant neoplasm affecting the liver, often diagnosed at an advanced stage and associated with an unfavorable overall prognosis. Sorafenib and Lenvatinib have emerged as first-line therapeutic drugs for advanced hepatocellular carcinoma, improving the prognosis for these patients. Nevertheless, the issue of tyrosine kinase inhibitor (TKI) resistance poses a substantial obstacle in the management of advanced hepatocellular carcinoma. The pathogenesis and advancement of hepatocellular carcinoma exhibit a close association with metabolic reprogramming, yet the attention given to lipid metabolism dysregulation in hepatocellular carcinoma development remains relatively restricted...
2024: Journal of Hepatocellular Carcinoma
https://read.qxmd.com/read/38216542/investigation-of-causal-relationships-between-cortical-structure-and-osteoporosis-using-two-sample-mendelian-randomization
#16
JOURNAL ARTICLE
Long-Jun Li, Xian-Xing Zhong, Guo-Zhi Tan, Ming-Xi Song, Pian Li, Zhen-Xin Liu, Si-Cheng Xiong, Da-Qi Yang, Zu-Jian Liang
The mutual interaction between bone characteristics and brain had been reported previously, yet whether the cortical structure has any relevance to osteoporosis is questionable. Therefore, we applied a two-sample bidirectional Mendelian randomization analysis to investigate this relationship. We utilized the bone mineral density measurements of femoral neck (n = 32,735) and lumbar spine (n = 28,498) and data on osteoporosis (7300 cases and 358,014 controls). The global surficial area and thickness and 34 specific functional regions of 51,665 patients were screened by magnetic resonance imaging...
January 12, 2024: Cerebral Cortex
https://read.qxmd.com/read/38200750/transcriptome-analysis-of-granulosa-cells-reveals-regulatory-mechanisms-related-to-chicken-follicle-development
#17
JOURNAL ARTICLE
Xubin Du, Qizhao Zhu, Huifang Pian, Xiaolong Yang, Dong Zhao, Xinyue Wu, Jiawen He, Debing Yu
In this study, we aimed to better understand the difference between the functions of the two types of granulosa cells and sought to discover more key genes involved in follicle development and follicle selection. Herein, we separately collected pre-hierarchical follicle granulosa cells (PHGCs) and preovulatory follicle granulosa cells (POGCs) for RNA extraction; the transcriptomes of the two groups were compared via RNA-seq. A total of 5273 differentially expressed genes (DEGs) were identified between the PHGCs and POGCs; 2797 genes were up-regulated and 2476 were down-regulated in the PHGCs compared with the POGCs...
December 20, 2023: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38178167/application-of-a-recombinant-novel-trypsin-from-trichinella-spiralis-for-serodiagnosis-of-trichinellosis
#18
JOURNAL ARTICLE
Lu Lu Han, Qi Qi Lu, Yang Li Li, Wen Wen Zheng, Pian Ren, Ruo Dan Liu, Jing Cui, Zhong Quan Wang
BACKGROUND: The excretory/secretory (ES) antigen of Trichinella spiralis muscle larvae (ML) is currently the most widely used diagnostic antigen to detect T. spiralis infection. However, this antigen has certain drawbacks, such as a complicated ES antigen preparation process and lower sensitivity during the early phase of infection. The aim of this study was to investigate the features of a novel T. spiralis trypsin (TsTryp) and evaluate its potential diagnostic value for trichinellosis...
January 4, 2024: Parasites & Vectors
https://read.qxmd.com/read/38156428/impacts-of-evidence-based-nursing-combined-with-enteral-nutrition-on-nutritional-status-and-quality-of-life-in-acute-cerebral-infarction-patients-a-randomized-controlled-trial
#19
JOURNAL ARTICLE
Jinfeng Dang, Guangling Li, Qiong Wu, Gaoyan Pian, Zhijun Wang
OBJECTIVE: To explore the impacts of evidence-based nursing (EBN) combined with enteral nutrition (EN) on nutritional status as well as quality of life in acute cerebral infarction (ACI) patients. METHODS: In this randomized controlled cluster trial, 80 ACI patients admitted to our hospital from January 2021 to December 2022 were selected and randomly separated into study group (SG) and control group (CG), with 40 patients in each group. Patients in CG received routine nursing, and patients in the SG received EBN combined with EN...
December 29, 2023: Perfusion
https://read.qxmd.com/read/38154059/asymmetric-synthesis-of-tertiary-%C3%AE-hydroxylation-cyclopentanones-via-synergetic-catalysis-of-chiral-at-metal-rhodium-iii-complexes-pyrrolidine
#20
JOURNAL ARTICLE
Jixin Pian, Zhifei Zhao, Yujie Zhao, Lin He, Xiong-Li Liu, Yongsheng Li, Shi-Wu Li
Catalytic and asymmetric domino Michael/aldol reaction of 1,2-dicarbonyl compounds with α,β-unsaturated ketones under the synergetic catalysis of chiral-at-metal rhodium complexes and pyrrolidine to deliver tertiary α-hydroxylation-cyclopentanones (45-89% yields with 81-99% ee and up to >20:1 dr) bearing three contiguous stereogenic centers had been established. Moreover, the scalability and practical utility of this protocol were well demonstrated by employing a gram-scale reaction and some representative transformations...
December 28, 2023: Journal of Organic Chemistry
keyword
keyword
109253
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.