keyword
https://read.qxmd.com/read/38536787/multiple-cardiovascular-risk-factor-care-in-55-low-and-middle-income-countries-a-cross-sectional-analysis-of-nationally-representative-individual-level-data-from-280-783-adults
#1
JOURNAL ARTICLE
Alpha Oumar Diallo, Maja E Marcus, David Flood, Michaela Theilmann, Nicholas E Rahim, Alan Kinlaw, Nora Franceschini, Til Stürmer, Dessie V Tien, Mohsen Abbasi-Kangevari, Kokou Agoudavi, Glennis Andall-Brereton, Krishna Aryal, Silver Bahendeka, Brice Bicaba, Pascal Bovet, Maria Dorobantu, Farshad Farzadfar, Seyyed-Hadi Ghamari, Gladwell Gathecha, David Guwatudde, Mongal Gurung, Corine Houehanou, Dismand Houinato, Nahla Hwalla, Jutta Jorgensen, Gibson Kagaruki, Khem Karki, Joao Martins, Mary Mayige, Roy Wong McClure, Sahar Saeedi Moghaddam, Omar Mwalim, Kibachio Joseph Mwangi, Bolormaa Norov, Sarah Quesnel-Crooks, Abla Sibai, Lela Sturua, Lindiwe Tsabedze, Chea Wesseh, Pascal Geldsetzer, Rifat Atun, Sebastian Vollmer, Till Bärnighausen, Justine Davies, Mohammed K Ali, Jacqueline A Seiglie, Emily W Gower, Jennifer Manne-Goehler
The prevalence of multiple age-related cardiovascular disease (CVD) risk factors is high among individuals living in low- and middle-income countries. We described receipt of healthcare services for and management of hypertension and diabetes among individuals living with these conditions using individual-level data from 55 nationally representative population-based surveys (2009-2019) with measured blood pressure (BP) and diabetes biomarker. We restricted our analysis to non-pregnant individuals aged 40-69 years and defined three mutually exclusive groups (i...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38536532/association-between-the-american-heart-association-s-new-life-s-essential-8-metrics-and-kidney-stone
#2
JOURNAL ARTICLE
Xingmo Dong, Lihua Liao, Yani Wang, Xueqin Lin, Weihua Chen, Huaijing Luo, Yi Yi, Dewen Zhong, Haifeng Wang, Zecong Ma, Yongfei Liu, Ying Liao
PURPOSE: The incidence of kidney stone disease has increased worldwide, resulting in high medical costs and social burden. Kidney stone disease shares some common features with the risk factors of cardiovascular diseases (CVDs). We investigated the association between cardiovascular health (CVH) based on the Life's Essential 8 (LE8) score developed by the American Heart Association and the incidence of kidney stone disease. METHODS: We analyzed the data of 29,469 US adults aged 20 years or above from the National Health and Nutrition Examination Survey, 2007-2018...
March 27, 2024: World Journal of Urology
https://read.qxmd.com/read/38535064/the-role-of-cardiovascular-magnetic-resonance-imaging-in-the-assessment-of-mitral-regurgitation
#3
REVIEW
Ioannis Botis, Maria-Anna Bazmpani, Stylianos Daios, Antonios Ziakas, Vasileios Kamperidis, Theodoros D Karamitsos
Mitral regurgitation (MR), a primary cause of valvular disease in adults, affects millions and is growing due to an ageing population. Cardiovascular magnetic resonance (CMR) has emerged as an essential tool, offering insights into valvular and myocardial pathology when compared to the primary imaging modality, echocardiography. This review highlights CMR's superiority in high-resolution volumetric assessment and tissue characterization, including also advanced techniques like late gadolinium enhancement imaging, parametric mapping, feature tracking and 4D flow analysis...
March 19, 2024: Diagnostics
https://read.qxmd.com/read/38534492/exploring-electrospun-scaffold-innovations-in-cardiovascular-therapy-a-review-of-electrospinning-in-cardiovascular-disease
#4
REVIEW
Mark Broadwin, Frances Imarhia, Amy Oh, Christopher R Stone, Frank W Sellke, Sankha Bhowmick, M Ruhul Abid
Cardiovascular disease (CVD) remains the leading cause of mortality worldwide. In particular, patients who suffer from ischemic heart disease (IHD) that is not amenable to surgical or percutaneous revascularization techniques have limited treatment options. Furthermore, after revascularization is successfully implemented, there are a number of pathophysiological changes to the myocardium, including but not limited to ischemia-reperfusion injury, necrosis, altered inflammation, tissue remodeling, and dyskinetic wall motion...
February 25, 2024: Bioengineering
https://read.qxmd.com/read/38533994/mobile-phone-text-messaging-for-medication-adherence-in-secondary-prevention-of-cardiovascular-disease
#5
REVIEW
Julie Redfern, Qiang Tu, Karice Hyun, Matthew A Hollings, Nashid Hafiz, Clara Zwack, Caroline Free, Pablo Perel, Clara K Chow
BACKGROUND: Cardiovascular diseases (CVDs) are the leading cause of death globally, accounting for almost 18 million deaths annually. People with CVDs have a five times greater chance of suffering a recurrent cardiovascular event than people without known CVDs. Although drug interventions have been shown to be cost-effective in reducing the risk of recurrent cardiovascular events, adherence to medication remains suboptimal. As a scalable and cost-effective approach, mobile phone text messaging presents an opportunity to convey health information, deliver electronic reminders, and encourage behaviour change...
March 27, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38533952/cost-effectiveness-of-increased-use-of-dual-antiplatelet-therapy-after-high-risk-transient-ischemic-attack-or-minor-stroke
#6
JOURNAL ARTICLE
Paul M Wechsler, Ankur Pandya, Neal S Parikh, Junaid A Razzak, Halina White, Babak B Navi, Hooman Kamel, Ava L Liberman
BACKGROUND: Rates of dual antiplatelet therapy (DAPT) after high-risk transient ischemic attack or minor ischemic stroke (TIAMIS) are suboptimal. We performed a cost-effectiveness analysis to characterize the parameters of a quality improvement (QI) intervention designed to increase DAPT use after TIAMIS. METHODS AND RESULTS: We constructed a decision tree model that compared current national rates of DAPT use after TIAMIS with rates after implementing a theoretical QI intervention designed to increase appropriate DAPT use...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533909/use-of-nonhuman-sera-as-a-highly-cost-effective-internal-standard-for-quantitation-of-multiple-human-proteins-using-species-specific-tryptic-peptides-applicability-in-clinical-lc-ms-analyses
#7
JOURNAL ARTICLE
Geraldine Williams, Lewis Couchman, David R Taylor, Jatinderpal K Sandhu, Oliver C Slingsby, Leong L Ng, Cajetan F Moniz, Donald J L Jones, Colleen B Maxwell
Quantitation of proteins using liquid chromatography-tandem mass spectrometry (LC-MS/MS) is complex, with a multiplicity of options ranging from label-free techniques to chemically and metabolically labeling proteins. Increasingly, for clinically relevant analyses, stable isotope-labeled (SIL) internal standards (ISs) represent the "gold standard" for quantitation due to their similar physiochemical properties to the analyte, wide availability, and ability to multiplex to several peptides. However, the purchase of SIL-ISs is a resource-intensive step in terms of cost and time, particularly for screening putative biomarker panels of hundreds of proteins...
March 27, 2024: Journal of Proteome Research
https://read.qxmd.com/read/38529169/effect-of-ketogenic-diet-on-obesity-and-other-metabolic-disorders-narrative-review
#8
REVIEW
Temesgen Baylie, Tiget Ayelgn, Markeshaw Tiruneh, Kibur Hunie Tesfa
Obesity is defined as an abnormal or excessive accumulation of fat that increases the burden of different chronic diseases in the population. It has reached epidemic proportions and is a major risk factor for a variety of diseases, including hypertension, cardiovascular disease, type 2 diabetes, dyslipidaemia, atherosclerosis, and some malignancies. Weight gain is a result of excessive energy intake compared to energy expenditure (energy loss from metabolism and physical exercise). A ketogenic diet has a more useful effect on obesity than other diets...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38526362/-non-inferiority-trials
#9
JOURNAL ARTICLE
Fabio Angeli, Paolo Verdecchia, Stefano Coiro, Andrea Santucci, Francesco Notaristefano, Claudia Bartolini, Gianpaolo Reboldi
Superiority trials are designed to test the hypothesis that a given diagnostic or therapeutic strategy is better than (i.e. "superior to") placebo or an active control. Conversely, non-inferiority trials test the hypothesis that a newer (i.e. alternative) strategy is not "unacceptably worse" than a control (i.e. "traditional", or "older") strategy. Non-inferiority trials are increasingly conducted in clinical medicine more often when a "newer" strategy is supposed to offer a relevant advantage in terms other than clinical efficacy (i...
April 2024: Giornale Italiano di Cardiologia
https://read.qxmd.com/read/38525711/the-relationship-between-vitamin-d-levels-and-blood-glucose-and-cholesterol-levels
#10
JOURNAL ARTICLE
Eman Elsheikh, Abdulhakim Ibrahim Alabdullah, Sarah Saleh Al-Harbi, Amal Omar Alagha, Dhiyaa Hassan AlAhmed, Mazen Moraya Ali Alalmaee
BACKGROUND: Vitamin D deficiency has reached epidemic proportions globally. Observational data link low vitamin D status to diabetes, dyslipidemia, and metabolic syndrome, but interventional trials on the effects of supplementation are limited. OBJECTIVE: We investigated associations between serum 25-hydroxyvitamin D (25(OH)D) levels and metabolic markers in Saudi adults. METHODS: This retrospective cross-sectional study analyzed the clinical records of 476 patients from Saudi Arabia, aged 15-78 years...
February 29, 2024: Clinics and Practice
https://read.qxmd.com/read/38524909/india-hypertension-control-initiative-blood-pressure-control-using-drug-and-dose-specific-standard-treatment-protocol-at-scale-in-punjab-and-maharashtra-india-2022
#11
JOURNAL ARTICLE
Prabhdeep Kaur, Manikandanesan Sakthivel, Vettrichelvan Venkatasamy, Padmaja Jogewar, Sandeep S Gill, Abhishek Kunwar, Meenakshi Sharma, Anupam Khungar Pathni, Kiran Durgad, Swagata Kumar Sahoo, Amol Wankhede, Navneet Kumar, Vishwajit Bharadwaj, Bidisha Das, Tejpalsinh Chavan, Suhas Khedkar, Lalit Sarode, Sampada D Bangar, Ashish Krishna, Roopa Shivashankar, Parasuraman Ganeshkumar, Pragati Pragya, Balram Bhargava
BACKGROUND: Hypertension treatment coverage is low in India. A stepwise simple treatment protocol is one of the strategies to improve hypertension treatment in primary care. We estimated the effectiveness of various protocol steps to achieve blood pressure (BP) control in public sector health facilities in Punjab and Maharashtra, India, where the India Hypertension Control Initiative (IHCI) was implemented. METHODS: We analyzed the records of people enrolled for hypertension treatment and follow-up under IHCI between January 2018 and December 2021 in public sector primary and secondary care facilities across 23 districts from two states...
2024: Global Heart
https://read.qxmd.com/read/38523709/multimorbidity-in-atherosclerotic-cardiovascular-disease-and-its-associations-with-adverse-cardiovascular-events-and-healthcare-costs-a-real-world-evidence-study
#12
JOURNAL ARTICLE
Dingwei Dai, Joaquim Fernandes, Xiaowu Sun, Laura Lupton, Vaughn W Payne, Alexandra Berk
Background: Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of mortality and disability in the United States and worldwide. Objective: To assess the multimorbidity burden and its associations with adverse cardiovascular events (ACE) and healthcare costs among patients with ASCVD. Methods: This is a retrospective observational cohort study using Aetna claims database. Patients with ASCVD were identified during the study period (1/1/2018-10/31/2021). The earliest ASCVD diagnosis date was identified as the index date...
2024: Journal of health economics and outcomes research
https://read.qxmd.com/read/38521293/folic-acid-and-plasma-lipids-interactions-and-effect-of-folate-supplementation
#13
REVIEW
Federica Fogacci, Carmine Pizzi, Luca Bergamaschi, Valentina Di Micoli, Arrigo F G Cicero
Dyslipidaemia and hyperhomocysteinemia are known risk factors for cardiovascular disease. While it is evident that optimization of plasma lipid is associated with low risk of cardiovascular disease in the general population, it is not yet fully clear whether reduction of homocysteinemia is associated with an improvement in risk in all subjects. The aim of our narrative review is to highlight eventual effects of folate supplementation on LDL-C levels, LDL-C oxidation and atherosclerosis-related complications...
March 21, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38521193/assessment-of-the-clot-children-s-likelihood-of-thrombosis-real-time-risk-prediction-model-of-hospital-associated-venous-thromboembolism-in-children-with-congenital-heart-disease
#14
JOURNAL ARTICLE
Sudeep D Sunthankar, Ryan P Moore, Daniel W Byrne, Henry J Domenico, Allison P Wheeler, Shannon C Walker, Prince J Kannankeril
BACKGROUND: Children with congenital heart disease (CHD) are at high risk for hospital-associated venous thromboembolism (HA-VTE). The Children's Likelihood of Thrombosis (CLOT) trial validated a real-time predictive model for HA-VTE using data extracted from the EHR for pediatric inpatients. We tested the hypothesis that addition of CHD specific data would improve model prediction in the CHD population. METHODS: Model performance in CHD patients from 2010-2022, was assessed using three iterations of the CLOT model: 1) the original CLOT model, 2) the original model refit using only data from the CHD cohort, and 3) the model updated with the addition of cardiopulmonary bypass time, STAT mortality category, height, and weight as covariates...
March 21, 2024: American Heart Journal
https://read.qxmd.com/read/38520327/harnessing-the-power-of-ai-a-comprehensive-review-of-left-ventricular-ejection-fraction-assessment-with-echocardiography
#15
JOURNAL ARTICLE
Ben Barris, Avrohom Karp, Menachem Jacobs, William H Frishman
The quantification of left ventricular ejection fraction (LVEF) has important clinical utility in the assessment of cardiac function and is vital for the diagnosis of cardiovascular diseases. A transthoracic echocardiogram serves as the most commonly used tool for LVEF assessment for several reasons, including, its noninvasive nature, great safety profile, real-time image processing ability, portability, and cost-effectiveness. However, transthoracic echocardiogram is highly dependent on the clinical skill of the sonographer and interpreting physician...
March 23, 2024: Cardiology in Review
https://read.qxmd.com/read/38518928/fused-thiophene-as-a-privileged-scaffold-a-review-on-anti-alzheimer-s-disease-potentials-via-targeting-cholinesterases-monoamine-oxidases-glycogen-synthase-kinase-3-and-a%C3%AE-aggregation
#16
REVIEW
Asmaa E Kassab, Ehab M Gedawy, Alaa S Sayed
As a "silent threat," Alzheimer's disease (AD) is quickly rising to the top of the list of costly and troublesome diseases facing humanity. It is growing to be one of the most troublesome and expensive conditions, with annual health care costs higher than those of cancer and comparable to those of cardiovascular disorders. One of the main pathogenic characteristics of AD is the deficiency of the neurotransmitter acetylcholine (ACh) which plays a vital role in memory, learning, and attention. Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) play a crucial role in hydrolyzing ACh...
March 20, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38517666/costs-attributable-to-hypercholesterolemia-in-a-single-period-and-over-the-life-cycle
#17
JOURNAL ARTICLE
Stephanie Reitzinger, Miriam Reiss, Thomas Czypionka
Hypercholesterolemia is a major risk factor for atherosclerotic cardiovascular disease leading to reduced (healthy) life years. The aim of this study is to quantify the societal costs associated with hypercholesterolemia. We use epidemiologic data on the distribution of cholesterol levels as well as data on relative risks regarding ischemic heart disease, stroke, and other cardiovascular diseases. The analytical approach is based on the use of population-attributable fractions applied to direct medical, direct non-medical and indirect costs using data of Austria...
March 22, 2024: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://read.qxmd.com/read/38517436/enrollment-in-high-deductible-health-plans-and-incident-diabetes-complications
#18
JOURNAL ARTICLE
Rozalina G McCoy, Kavya S Swarna, David H Jiang, Holly K Van Houten, Jie Chen, Esa M Davis, Jeph Herrin
IMPORTANCE: Preventing diabetes complications requires monitoring and control of hyperglycemia and cardiovascular risk factors. Switching to high-deductible health plans (HDHPs) has been shown to hinder aspects of diabetes care; however, the association of HDHP enrollment with microvascular and macrovascular diabetes complications is unknown. OBJECTIVE: To examine the association between an employer-required switch to an HDHP and incident complications of diabetes...
March 4, 2024: JAMA Network Open
https://read.qxmd.com/read/38515115/the-burden-of-cardiovascular-diseases-in-jordan-a-longitudinal-analysis-from-the-global-burden-of-disease-study-1990-2019
#19
JOURNAL ARTICLE
Yazan A Al-Ajlouni, Omar Al Ta'ani, Ghaith Shamaileh, Yazan Nagi, Mohammad Tanashat, Farah Al-Bitar, Dustin T Duncan, Nour Makarem
BACKGROUND: Cardiovascular Disease (CVD) is the leading cause of mortality worldwide. While countries in the Arab world continue to lack public health data and be severely understudied in health research, previous research has shown that compared to 1990, CVDs had a higher burden of disease in the Arab World in 2010. Jordan, a middle-income Arab country, is profiled with unique attributes such as a dual-sector healthcare system, political stability, and its role as a haven for refugees and migrants...
March 21, 2024: BMC Public Health
https://read.qxmd.com/read/38514143/evidence-for-clinician-underprescription-of-and-patient-non-adherence-to-guideline-recommended-cardiovascular-medications-among-adults-with-peripheral-artery-disease-protocol-for-a-systematic-review-and-meta-analysis
#20
JOURNAL ARTICLE
David de Launay, Maude Paquet, Aidan M Kirkham, Ian D Graham, Dean A Fergusson, Sudhir K Nagpal, Risa Shorr, Jeremy M Grimshaw, Derek J Roberts
INTRODUCTION: International guidelines recommend that adults with peripheral artery disease (PAD) be prescribed antiplatelet, statin and antihypertensive medications. However, it is unclear how often people with PAD are underprescribed these drugs, which characteristics predict clinician underprescription of and patient non-adherence to guideline-recommended cardiovascular medications, and whether underprescription and non-adherence are associated with adverse health and health system outcomes...
March 21, 2024: BMJ Open
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