Robert Bränström, Pim P van Krieken, Robin Fröbom, C Christofer Juhlin, Ivan Shabo, Barbara Leibiger, Ingo B Leibiger, Per-Olof Berggren, Craig A Aspinwall
The parathyroid cell is a vital regulator of extracellular calcium levels, operating through the secretion of parathyroid hormone (PTH). Despite its importance, the regulation of PTH secretion remains complex and not fully understood, representing a unique interplay between extracellular and intracellular calcium, and hormone secretion. One significant challenge in parathyroid research has been the difficulty in maintaining cells ex vivo for in-depth cellular investigations. To address this issue, we introduce a novel platform for parathyroid cell transplantation and noninvasive in vivo imaging using the anterior chamber of the eye as a transplantation site...
2024: Cell Transplantation