keyword
https://read.qxmd.com/read/37944928/prognostic-impact-of-agr3-protein-expression-in-breast-cancer-a-systematic-review-and-meta-analysis
#21
JOURNAL ARTICLE
Carolina Leão de Moraes, Carolina Rodrigues Mendonça, Natália Cruz E Melo, Fernanda Sardinha de Abreu Tacon, Jair Pereira de Melo Junior, Waldemar Naves do Amaral
OBJECTIVE:  To investigate the clinicopathological significance and prognosis of the expression of the anterior gradient 3 (AGR3) protein in women with breast cancer. DATA SOURCES:  The PubMed, CINAHL, EMBASE, Scopus, and Web of Science databases were searched for studies published in English and without restrictions regarding the year of publication. The search terms were: breast cancer AND anterior gradient 3 OR AGR3 expression . STUDY SELECTION:  We included observational or interventional studies, studies on AGR3 protein expression by immunohistochemistry, and studies on invasive breast cancer...
October 2023: Revista Brasileira de Ginecologia e Obstetrícia
https://read.qxmd.com/read/37944926/immobilization-lymphedema-and-obesity-are-predictive-factors-in-the-development-of-adhesive-capsulitis-in-breast-cancer-patients
#22
JOURNAL ARTICLE
Marcos Rassi Fernandes, Flaviane Marques de Assis, Joana Ermida Spagnol, Vinícius Barros Chaves
OBJECTIVE:  Adhesive capsulitis is a condition characterized by shoulder pain and stiffness. Breast cancer treatment has been linked to the development of this condition, but its mechanisms are still little known. This study's objective was to identify predictors factors associated with the development of adhesive capsulitis in breast cancer patients. METHODS:  A case control study was performed with women undergoing treatment for breast cancer in a single center...
October 2023: Revista Brasileira de Ginecologia e Obstetrícia
https://read.qxmd.com/read/37929890/-nutrition-in-breast-cancer-genesis
#23
JOURNAL ARTICLE
Bricia López-Plaza, Laura M Bermejo, Viviana Loria-Kohen, Edwin Fernández-Cruz
Breast cancer is the most prevalent tumor in women, ranking first in incidence and mortality in many countries. Although the causes of breast cancer are complex and multifactorial, nutritional factors and those related to nutritional status play an important role in the development of the disease. In this way, factors that increase breast cancer risk have been identified, such as weight gain, the amount of adipose tissue, waist circumference, alcohol consumption or the consumption of red meat and processed meat, while other factors have been identified that reduce the risk, such as eating fruits and vegetables...
October 19, 2023: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/37871573/complete-pathological-response-in-patients-with-her2-positive-breast-cancer-treated-with-neoadjuvant-therapy-in-colombia
#24
JOURNAL ARTICLE
Mauricio Rodríguez, Diego M González, Farah El-Sharkawy, Mileny Castaño, Jorge Madrid
INTRODUCTION: Breast cancer is the most common type of cancer and the leading cause of death by cancer in women in Colombia. Approximately 15 to 20% of breast cancers overexpress HER2. OBJECTIVE: To analyze the relationship between multiple clinical and histological variables and pathological complete response in patients with HER2-positive breast cancer undergoing neoadjuvant therapy in a specialized cancer center in Colombia. MATERIALS AND METHODS: We performed a retrospective analysis of non-metastatic HER2-positive breast cancer patients who received neoadjuvant therapy between 2007 and 2020 at the Instituto de Cancerología Las Americas Auna (Medellín, Colombia)...
September 30, 2023: Biomédica: Revista del Instituto Nacional de Salud
https://read.qxmd.com/read/37865228/detection-of-internal-mammary-chain-infiltration-in-breast-cancer-patients-by-18f-fdg-pet-mri-therapy-implications
#25
JOURNAL ARTICLE
J R Garcia, M Kauak, A Compte, P Bassa, E Llinares, E Valls, E Riera
OBJECTIVE: To evaluate the detection rate and therapeutic implication of the infiltration of the internal mammary chain (IMCI) by [18 F]FDG PET/MRI for staging of patients with breast cancer. METHODS: Prospective study including 41 women with breast cancer (stage ≥ IIB) staged by [18 F]FDG PET/MR. Two-phase exam: breast imaging (prone), whole-body (supine). TNM stage assessed by peer consensus with Nuclear Medicine and Radiology specialists...
October 19, 2023: Revista española de medicina nuclear e imagen molecular
https://read.qxmd.com/read/37846186/core-needle-biopsy-accuracy-for-androgen-receptor-expression-in-invasive-breast-cancer
#26
JOURNAL ARTICLE
Marcelle Morais Dos Santos, Antonio Luiz Frasson, Vinicius Duval da Silva, Aluísio de Castro Antunes Maciel, Guilherme Watte, Gustavo Werutsky, Tomás Reinert, André Poisl Fay
OBJECTIVE:  Breast cancer (BC) biomarkers, such as hormone receptors expression, are crucial to guide therapy in BC patients. Antiandrogens have been studied in BC; however, limited data are available on androgen receptor (AR) expression test methodology. We aim to report the core needle biopsy (CNB) accuracy for AR expression in BC. METHODS:  Patients diagnosed with stage I-III invasive BC from a single institution were included. Androgen receptor expression was evaluated by immunohistochemistry (IHC) using 1 and 10% cutoff and the AR expression in surgical specimens (SS) was the gold standard...
September 2023: Revista Brasileira de Ginecologia e Obstetrícia
https://read.qxmd.com/read/37827047/quality-indicators-for-the-diagnosis-and-treatment-of-breast-cancer-integrated-assistance-a-critical-appraisal
#27
JOURNAL ARTICLE
M Maes-Carballo, M Martín-Díaz, L Mignini, K S Khan, R Trigueros, A Bueno-Cavanillas
INTRODUCTION: Quality indicators (QIs) are essential for adequate control of the health care management process, recognizing areas of improvement and providing solutions. We aimed to evaluate the Integrated Breast Cancer (BC) Care Process QIs. METHODS: We studied 487 consecutive BC cases diagnosed from November 1st, 2013, to November 30th, 2019, in a Spanish healthcare area, and we estimated the associated QIs. RESULTS: Four indicators did not meet the standards and were analysed based on related sociodemographic and clinical variables...
October 10, 2023: Semergen
https://read.qxmd.com/read/37735004/abemaciclib-as-adjuvant-treatment-for-high-risk-early-breast-cancer
#28
JOURNAL ARTICLE
Ganfornina Andrades Ana, Fénix Caballero Silvia, Salguero Olid Alba, Alegre Del-Rey Emilio Jesús
OBJECTIVE: To adapt the GHEMA report of abemaciclib, an inhibitor of cyclin-dependent kinases 4 and 6. European Medicines Agency authorization (April 2022) includes, in combination with endocrine therapy, the adjuvant treatment of adult patients with hormone receptor positive, human epidermal growth factor receptor 2 negative, node-positive, early breast cancer at high risk of recurrence. METHOD: The efficacy and safety of abemaciclib were evaluated in a randomized, open-label, and multicenter phase III study...
September 19, 2023: Farmacia Hospitalaria
https://read.qxmd.com/read/37729357/survivin-expression-as-a-prognostic-marker-for-breast-cancer
#29
JOURNAL ARTICLE
Patricia Quidute, Ricardo Quidute, Matheus Moreira Perez, Edimar Cristiano Pereira, Glaucia Luciano da Veiga, Beatriz da Costa Aguiar Alves, Fernando Luiz Affonso Fonseca
OBJECTIVE: Due to the speed of development observed in breast cancer, several studies aimed at discovering new biomarkers have been carried out in order to arrive at an early diagnosis. As survivin plays a fundamental role in the evasion of apoptosis in tumor cells, the aim of this study was to verify the expression profile of the survivin gene in paraffin-embedded breast tumor samples and associate it with the clinical characteristics of the patients. METHODS: This is a cross-sectional study, for which 100 tumor samples were obtained from cancer patients treated throughout the year 2019 at Instituto de Mama do Cariri (Juazeiro do Norte, in the state of Ceará)...
2023: Revista da Associação Médica Brasileira
https://read.qxmd.com/read/37690338/-scientific-letter-evaluating-acupuncture-and-auriculotherapy-action-in-arthralgia-associated-with-hormone-therapy-in-breast-cancer
#30
JOURNAL ARTICLE
Isabel Giralt, Gilda Delmira Carvajal, Rafael Fabregas, Sonia Baulies
No abstract text is available yet for this article.
September 8, 2023: Atencion Primaria
https://read.qxmd.com/read/37683660/recommendations-for-the-screening-of-breast-cancer-of-the-brazilian-college-of-radiology-and-diagnostic-imaging-brazilian-society-of-mastology-and-brazilian-federation-of-gynecology-and-obstetrics-association
#31
JOURNAL ARTICLE
Linei Augusta Brolini Delle Urban, Luciano Fernandes Chala, Ivie Braga de Paula, Selma di Pace Bauab, Marcela Brisighelli Schaefer, Ana Lúcia Kefalás Oliveira, Carlos Shimizu, Tatiane Mendes Gonçalves de Oliveira, Paula de Camargo Moraes, Beatriz Medicis Maranhão Miranda, Flávia Engel Aduan, Salete de Jesus Fonseca Rego, Ellyete de Oliveira Canella, Henrique Lima Couto, Gustavo Machado Badan, José Luis Esteves Francisco, Thaís Paiva Moraes, Rosangela Requi Jakubiak, João Emílio Peixoto
OBJECTIVE:  To present the update of the recommendations of the Brazilian College of Radiology and Diagnostic Imaging, the Brazilian Society of Mastology and the Brazilian Federation of Associations of Gynecology and Obstetrics for breast cancer screening in Brazil. METHODS:  Scientific evidence published in Medline, EMBASE, Cochrane Library, EBSCO, CINAHL and Lilacs databases between January 2012 and July 2022 was searched. Recommendations were based on this evidence by consensus of the expert committee of the three entities...
August 2023: Revista Brasileira de Ginecologia e Obstetrícia
https://read.qxmd.com/read/37677941/agreement-between-incisional-and-excisional-biopsies-for-hormone-receptors-and-her2-in-breast-cancer
#32
JOURNAL ARTICLE
Fernando Candanedo-Gonzalez, Juan C Cordova-Ramón, Jessica Smeke-Smeke, Wilfredo Valenzuela-Gonzalez, Armando Gamboa-Dominguez
INTRODUCTION: Breast cancer is the leading cause of cancer mortality in Mexican women. OBJECTIVE: The objective of the study was to identify concordances among core needle biopsy (CNB) and excisional biopsies (EB) regarding diagnosis, hormonal receptors (HR), and human epidermal growth factor receptor 2 (Her2). MATERIALS AND METHODS: Core number, demographic data, histological type, and treatment were documented for each sample. Reported HR and Her2 score from both samples were compiled...
2023: Cirugia y Cirujanos
https://read.qxmd.com/read/37531539/breast-cancer-care-network-coordination-analysis-in-the-light-of-the-lean-methodology-for-early-diagnosis
#33
JOURNAL ARTICLE
Ana Gerúsia Souza Ribeiro Gurgel, Joyce Mazza Nunes Aragão, Maristela Inês Osawa Vasconcelos, Aline Lima Pestana Magalhães, Gerardo Cristino Filho, José Reginaldo Feijão Parente
This study aimed to analyze the application of the lean philosophy in the Health Care Network (RAS) for the early diagnosis of breast cancer. This case study was produced with data from interviews, document analysis, and observation and was conducted from June to July 2019. The setting was the seat of the municipality of the North Metropolitan Region, Ceará State, Brazil, involving three points of the RAS (Primary Care Unit, Medical Specialties Center, and Polyclinic). The following issues were identified: long waiting times, first-come-first-served care, and insufficient medical workload...
August 2023: Ciência & Saúde Coletiva
https://read.qxmd.com/read/37523685/-respuesta-tumoral-a-la-quimioterapia-neoadyuvante-en-subtipos-moleculares-de-c%C3%A3-ncer-de-mama-en-medell%C3%A3-n-colombia-estudio-de-cohorte-retrospectivo
#34
JOURNAL ARTICLE
Manuela Restrepo-Mejía, Ana Maria Guarín-García, Óscar Alejandro Bonilla-Sepúlveda, Melissa Rincón-Medina, Lina Marcela Barrera-Arenas
OBJETIVOS: describir la frecuencia de la respuesta clínica y patológica, entre los diferentes subtipos moleculares de cáncer de mama, en pacientes que previamente recibieron quimioterapia neoadyuvante. Materiales y métodos: cohorte retrospectiva, descriptiva. Se incluyeron mujeres mayores de 18 años, con diagnóstico histológico de carcinoma invasivo de mama, en estadios IIA, IIB, IIIA, IIIB y IIIC, con clasificación por subtipos moleculares, que hubieran recibido quimioterapia neoadyuvante, atendidas en una clínica de alto nivel de complejidad localizada en Medellín (Colombia), entre el 1 de julio de 2017 y el 30 de julio de 2019...
June 30, 2023: Revista Colombiana de Obstetricia y Ginecología
https://read.qxmd.com/read/37436327/factors-associated-with-time-to-treatment-initiation-of-breast-cancer
#35
JOURNAL ARTICLE
Rafael Tavares Jomar, Nathália Sodré Velasco, Gelcio Luiz Quintella Mendes, Raphael Mendonça Guimarães, Vitor Augusto de Oliveira Fonseca, Karina Cardoso Meira
The present retrospective study investigated factors associated with time-to-treatment initiation of breast cancer of a cohort of 12,100 cases of health facilities qualified for high complexity in oncology within the scope of the Brazilian Public Health System (SUS) of Rio de Janeiro between 2013 and 2019. Multivariate logistic regression was used to estimate odds ratios and 95% confidence intervals. Of all cases, 82.1% were submitted to the first treatment >60 days. Patients without previous diagnosis history, higher education and in stages III and IV were less likely to have their first treatment >60 days, while treatment at a health facility outside the capital showed a higher probability...
July 2023: Ciência & Saúde Coletiva
https://read.qxmd.com/read/37433152/effect-of-sitagliptin-on-down-regulation-of-kat7-and-sirt1-gene-expression-in-breast-cancer-cell-line-mcf7
#36
JOURNAL ARTICLE
Tanya C Ruteaga-Navarro, Miguel A Reyes-Romero, Quitzia L Torres-Salazar
BACKGROUND: To date, the main clinical interest in DPP4 is focused on its inhibition in diabetic patients to prolong the half-life of incretins. Epigenetic alterations resulting from DPP4 inhibition have been poorly explored. OBJECTIVE: The objective of this study was to determine, whether sitagliptin, a DPP4 inhibitor, has effects on the expression of KAT7 and SIRT1 (genes encoding a histone acetyltransferase and a histone deacetylase, respectively) in MCF7 breast cancer cells, which play an essential role in modulating the epigenetic landscape of chromatin...
2023: Cirugia y Cirujanos
https://read.qxmd.com/read/37422262/nuclear-medicine-contribution-to-precision-surgery-in-breast-cancer
#37
JOURNAL ARTICLE
Renato A Valdés Olmos, Sergi Vidal-Sicart
Nuclear medicine has significantly contributed to precision surgery in breast cancer in the past decades. Radioguided surgery (RGS) has enabled sentinel node (SN) biopsy in assessing regional nodal involvement modifying the management of patients with early breast cancer. For the axilla the SN procedure has resulted in fewer complications and better quality of life when compared with axillary lymph node dissection. Originally, SN biopsy principally concerned cT 1-2 tumours without evidence of axillary lymph node metastases...
July 7, 2023: Revista española de medicina nuclear e imagen molecular
https://read.qxmd.com/read/37402295/-not-available
#38
JOURNAL ARTICLE
Bernardo Arce, Nora Grañana
ANTECEDENTES: Los pacientes con cáncer de mama pueden experimentar dificultades cognitivas por recibir quimioterapia. Dicha alteración es denominada Deterioro Cognitivo Quimioinducido, también es conocida como Chemobrain o Chemofog. OBJETIVO: Identificar el perfil cognitivo y las características de la evaluación neuropsicológica de esta población. Método: Se consultaron las bases de datos PubMed, SpringerLink y SciELO. Se seleccionaron artículos de 1994 hasta septiembre de 2021...
June 30, 2023: Revista de la Facultad de Ciencias Médicas
https://read.qxmd.com/read/37339643/effect-of-combined-training-on-body-image-body-composition-and-functional-capacity-in-patients-with-breast-cancer-controlled-clinical-trial
#39
JOURNAL ARTICLE
Andréa Dias Reis, Paula Tâmara Vieira Teixeira Pereira, Jurema Gonçalves Lopes Castro Filha, Evelyn Feitosa Rodrigues, Isadora Pinheiro Laranjeira, Bianca Trovello Ramallo, Marcela Rodrigues de Castro, Fabrício Eduardo Rossi, Ismael Forte Freitas Júnior, João Batista Santos Garcia
OBJECTIVE:  Evaluate the effect of combined training on body image (BI), body composition and functional capacity in patients with breast cancer. As also the relationship of BI with body composition and functional capacity. METHODS:  This was a Controlled Clinical Trial study, this study including 26 patients with breast cancer (30 to 59 years). The training group (n = 13) underwent 12 weeks of training, including three 60-min sessions of aerobic exercise and resistance training, and two sessions of flexibility training per week; each flexibility exercise lasted 20s...
May 2023: Revista Brasileira de Ginecologia e Obstetrícia
https://read.qxmd.com/read/37255158/effectiveness-of-adjuvant-trastuzumab-in-women-with-her-2-breast-cancer-in-the-sus
#40
JOURNAL ARTICLE
Joanna d'Arc Lyra Batista, Rafael José Vargas Alves, Taís Belladona Cardoso, Marcelo Moreno, Katsuki Arima Tiscoski, Carisi Anne Polanczyk
The aim of this study was to evaluate the effectiveness in a real-world study of adjuvant trastuzumab in women with HER-2+ initial breast cancer in overall survival and recurrence-free survival. A retrospective cohort study was conducted with women who had HER-2+ breast cancer treated with trastuzumab from July 2012 to May 2017 and followed up until July 2021. The death rate was 2.62 per 100 persons/year, and the incidence rate of recurrence was 7.52 per 100 persons/year. The probability of survival at 8.7 years was 85...
June 2023: Ciência & Saúde Coletiva
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