Qi Wang, Shen Wang, Zhikang Shi, Zhengrong Li, Yongkun Zhao, Na Feng, Jinhao Bi, Cuicui Jiao, Entao Li, Tiecheng Wang, Jianzhong Wang, Hongli Jin, Pei Huang, Feihu Yan, Songtao Yang, Xianzhu Xia
The Crimean Congo Hemorrhagic Fever Virus (CCHFV) is a tick-borne bunyavirus of the Narovirus genus, which is the causative agent of Crimean Congo Hemorrhagic Fever (CCHF). CCHF is endemic in Africa, the Middle East, Eastern Europe and Asia, with a high case-fatality rate of up to 50% in humans. Currently, there are no approved vaccines or effective therapies available for CCHF. The GEM-PA is a safe, versatile and effective carrier system, which offers a cost-efficient, high-throughput platform for recovery and purification of subunit proteins for vaccines...
July 28, 2022: Viruses