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V F Artiukhov, V V Gusinskaia, E A Mikhileva
The effect of the UV-irradiation (75.5-2265 J/m2) on the nitrogen oxide (NO) and the tumor necrosis factor-alpha (TNF-alpha) production by neutrophils of human blood was studied by Griess method based on the accumulation of NO2(-) -ions in the incubation matter and on the enzyme-linked immunosorbent assay (ELISA). UV-irradiation in the dose of 75.5 J/m2 reveals the correctional effect relatively to the native level of NO, providing the maintenance of the physiological homeostasis. The irradiation of the neutrophils by the doses of 755 and 2265 J/m2 increases the concentration of NO metabolites, that might lead to different pathologies...
September 2005: Radiatsionnaia Biologiia, Radioecologiia
No abstract text is available yet for this article.
March 1963: Archives of Biochemistry and Biophysics
G Telegdy, J W Weeks, U Lerner, G Stakemann, E Diczfalusy
No abstract text is available yet for this article.
January 1970: Acta Endocrinologica
C Demetrescu, C Chirită, V Ion
No abstract text is available yet for this article.
December 1967: Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft
T W Doouss, N Deshpande, J I Burn
No abstract text is available yet for this article.
November 1968: British Journal of Surgery
R N Butler, K K Arora, J G Collins, I Flanigan, M J Lawson, I C Roberts-Thomson, J F Williams
The colonic cells of the large intestine are one of the most proliferative tissues of the animal body. The pentose pathway has an essential role in cell division and growth being the only pathway forming ribose 5-P necessary for all nucleotide and nucleic acid sunthesis. The pentose pathway may also provide reducing potential as NADPH for biosynthesis and C-3- C-8 glycolyl compounds. The maximum catalytic capacities of the reactions of the non-oxidative pentose pathway for the conversion of ribose 5-P to hexose and triose phosphates by the proximal and distal colon under feeding and starvation regimes are among the highest in the animal body...
October 1990: Biochemistry International
M G Ferlin, G Chiarelotto, O Gia, F Baccichetti, F Carlassare
2-Carbomethoxy-N-methyl-1H-pyrrolo[2,3-f]quinolinium and isoquinolinium iodides were prepared. Their in vitro ability to form complexes with DNA is enhanced in respect to parent compounds. This, however, does not appear to be agreement with their ability to inhibit cellular DNA sunthesis.
June 1991: Il Farmaco
J D Clement-Metral, F Fanica-Gaignier
The two 5-aminolevulinic acid synthetases of Rhodopseudomonas spheroides Y. were extracted from cells grown in a 'low-iron' medium and purified. They have a specific activity 10-fold higher than the 'high-iron' enzymes described by us previously and have the same properties except that they do not contain any iron and have one free-SH group more per mole of enzyme (2 for E1; , for E2) Their inhibition by adenosine triphosphate and iron and their oxidation-reduction sensitivity are discussed in terms of light, oxygen and heme feed-back regulation of bacteriochlorophyll sunthesis...
November 1, 1975: European Journal of Biochemistry
M P Georgiadis
A Michael type addition of an amine to 6-methoxy-2-methyl-2-(4'-biphenylyl)-2H-pyran-3(6H)-one (1) dissolved in ether, benzene, or THF gave 5-amino derivatives of 5,6-dihydro-6-methoxy-2-methyl-2-(4'-biphenylyl)-2H-pyran-3(4H)-one (2). These by subsequent reduction with LiAlH4 were converted to 5-amino derivatives of 6-methoxy-2-methyl-2-(4'-biphenylyl)tetrahydro-2H-pyran-3-ol (3). Both isomers A and B of 1 (in regard to the methoxy group at C6) were used for the synthesis of 2 and 3. The in vitro antimicrobial activity of the amine adducts 2 was of the same order of magnitude as the starting material...
February 1976: Journal of Medicinal Chemistry
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