Pengchen Chen, Yali Song, Li Tang, Wenbin Zhong, JingJing Zhang, Min Cao, Junhui Chen, Guangqing Cheng, Huiying Li, Tianyun Fan, Hang Fai Kwok, Jigang Wang, Chuanbin Yang, Wei Xiao
Tributyltin chloride (TBTCL), a commonly used antiseptic substance, is commonly found in the environment. Human exposure to TBTCL through the consumption of contaminated seafood, fish, or drinking water has aroused concern. It is well-characterized that TBTCL has multiple detrimental effects on the male reproductive system. However, the potential cellular mechanisms are not fully elucidated. Here, we characterized molecular mechanisms of TBTCL-induced cell injury in Leydig cells, a critical supporter for spermatogenesis...
April 15, 2023: Journal of Hazardous Materials