Sven Poli, Carsten Grohmann, Daniel A Wenzel, Khouloud Poli, Johannes Tuennerhoff, Max Nedelmann, Jens Fiehler, Hansjürgen Agostini, Bruce Campbell, Dominik M Fischer, Marek Sykora, Brian Mac Grory, Nicolas Feltgen, David J Seiffge, Daniel Strbian, Maximilian Schultheiß, Martin S Spitzer
RATIONALE: Meta-analyses of case series of non-arteritic central retinal artery occlusion (CRAO) indicate beneficial effects of intravenous thrombolysis when initiated early after symptom onset. Randomized data is lacking to address this question. AIMS: REVISION investigates intravenous alteplase within 4.5 hours of monocular vision loss due to acute CRAO. METHODS: Randomized (1:1), double-blind, placebo-controlled, multicenter adaptive phase III trial...
April 9, 2024: International Journal of Stroke: Official Journal of the International Stroke Society