Ya-Wei Li, Huai-Jin Li, Hui-Juan Li, Bin-Jiang Zhao, Xiang-Yang Guo, Yi Feng, Ming-Zhang Zuo, Yong-Pei Yu, Hao Kong, Yi Zhao, Da Huang, Chun-Mei Deng, Xiao-Yun Hu, Peng-Fei Liu, Yan Li, Hai-Yan An, Hong-Ye Zhang, Mei-Rong Wang, Yang-Feng Wu, Dong-Xin Wang, Daniel I Sessler
BACKGROUND: Delirium is a common and serious postoperative complication, especially in the elderly. Epidural anesthesia may reduce delirium by improving analgesia, reducing opioid consumption, and blunting stress response to surgery. This trial therefore tested the hypothesis that combined epidural-general anesthesia reduces the incidence of postoperative delirium in elderly patients recovering from major noncardiac surgery. METHODS: Patients aged 60 to 90 yr scheduled for major noncardiac thoracic or abdominal surgeries expected to last 2 h or more were enrolled...
August 1, 2021: Anesthesiology