keyword
https://read.qxmd.com/read/38494567/single-center-experience-with-alpps-and-timing-with-stage-2-in-patients-with-fibrotic-cirrhotic-liver
#1
JOURNAL ARTICLE
Kuo-Chen Hung, Hao-Ping Wang, Wei-Feng Li, Yu-Cheng Lin, Chih-Chi Wang
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a novel procedure for major resection in patients with insufficient future liver remnant (FLR). Effective FLR augmentation is pivotal in the completion of ALPPS. Liver fibrosis/cirrhosis associated with chronic viral hepatitis impairs liver regeneration. To investigate the augmentation of FLR in associating ALPPS between patients with fibrotic/cirrhotic livers (FL) and non-fibrotic livers (NFL) and compare their short-term clinical outcomes and long-term survival...
March 17, 2024: Updates in Surgery
https://read.qxmd.com/read/38473426/robotic-complete-alpps-ralpps-first-german-experiences
#2
JOURNAL ARTICLE
Jörg Arend, Mareike Franz, Alexander Rose, Christine March, Mirhasan Rahimli, Aristotelis Perrakis, Eric Lorenz, Roland Croner
BACKGROUND: ALPPS leads to fast and effective liver hypertrophy. This enables the resection of extended tumors. Conventional ALPPS is associated with high morbidity and mortality. MILS reduces morbidity and the robot adds technical features that make complex procedures safe. MATERIAL AND METHODS: The MD-MILS was screened for patients who underwent rALPPS. Demographic and perioperative data were evaluated retrospectively. Ninety days postoperative morbidity was scored according to the CD classification...
March 6, 2024: Cancers
https://read.qxmd.com/read/38314815/a-mouse-model-of-the-associating-liver-partition-and-portal-vein-ligation-for-staged-hepatectomy-procedure-aided-by-microscopy
#3
JOURNAL ARTICLE
Chong Hu, Zhidan Xu, Yuan Du
Hepatectomy is widely regarded as the primary treatment for hepatic malignancies; yet, postoperative liver failure remains a major cause of perioperative mortality, severely impacting patient outcomes. In a robust hepatic environment, the future liver remnant (FLR) must exceed 25%, and in cases of cirrhosis, this requirement increases to over 40%. The inadequacy of FLR is currently a major obstacle in the progression of hepatic surgery. Traditional methods to enhance FLR hypertrophy mainly focus on portal vein embolization (PVE), but its effectiveness is considerably limited...
January 19, 2024: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/38109444/alpps-procedure-for-the-treatment-of-bilobar-multiple-liver-metastasis-from-colorectal-cancer-first-case-in-rn-macedonia
#4
JOURNAL ARTICLE
Rexhep Selmani, Zoran Karadzov, Goran Begovic, Qemal Rushiti, Shaban Memeti, Magdalena G Dimitrova, Tanja Spirovska, Marija Atanasova, Arian Selmani
Introduction : ALPPS (Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy), is a recently developed procedure, first performed by HJ Schlitt in Regensburg, Germany. The technique developed two stages of hepatectomy. The ALPPS procedure has been introduced to increase the volume of future liver remnant, much more than the other technique, such as PVE (portal vein embolization). The first ALPPS in our country was introduced and performed by our team on May 15th, 2018. Results : The 60-year-old patient was previously operated on for rectal cancer in 2017 at another institution...
December 1, 2023: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/38067316/promising-outcomes-of-modified-alpps-for-staged-hepatectomy-in-cholangiocarcinoma
#5
JOURNAL ARTICLE
Arianeb Mehrabi, Mohammad Golriz, Ali Ramouz, Elias Khajeh, Ahmed Hammad, Thilo Hackert, Beat Müller-Stich, Oliver Strobel, Sadeq Ali-Hasan-Al-Saegh, Omid Ghamarnejad, Mohammed Al-Saeedi, Christoph Springfeld, Christian Rupp, Philipp Mayer, Markus Mieth, Benjamin Goeppert, Katrin Hoffmann, Markus W Büchler
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a two-stage procedure that can potentially cure patients with large cholangiocarcinoma. The current study evaluates the impact of modifications on the outcomes of ALPPS in patients with cholangiocarcinoma. In this single-center study, a series of 30 consecutive patients with cholangiocarcinoma (22 extrahepatic and 8 intrahepatic) who underwent ALPPS between 2011 and 2021 was evaluated. The ALPPS procedure in our center was modified in 2016 by minimizing the first stage of the surgical procedure through biliary externalization after the first stage, antibiotic administration during the interstage phase, and performing biliary reconstructions during the second stage...
November 28, 2023: Cancers
https://read.qxmd.com/read/38050321/liver-venous-deprivation-for-rapid-liver-hypertrophy-before-major-hepatectomy-a-case-report
#6
JOURNAL ARTICLE
Nathan John, Lisandro Montorfano, Arun Nagarajan, Conrad H Simpfendorfer, Steven D Wexner, Parag Amin, Mayank Roy
Liver venous deprivation (LVD) is an emerging, minimally invasive strategy to induce rapid liver hypertrophy of the future liver remnant (FLR) before a major hepatectomy. LVD (aka "double vein embolization") entails same-session percutaneous embolization of the portal and hepatic veins of the planned liver resection. This report discusses LVD's utilization and technical challenges in managing a 49-year-old male with recurrent multifocal colorectal liver metastases (CRLM). The patient initially underwent neoadjuvant FOLFOX chemotherapy followed by a simultaneous laparoscopic sigmoid colectomy and liver surgery (microwave ablation of segment V and wedge resections of segment one and IVb), followed by completion of chemotherapy...
November 2023: American Surgeon
https://read.qxmd.com/read/37980965/laparoscopic-hybrid-mini-alpps-using-transmesenteric-intra-operative-portal-embolization-for-locally-advanced-intrahepatic-cholangiocarcinoma
#7
César Muñoz, Miguel Naranjo, Carlos Varela, Jesús Rojas
Supplementary material related to this article can be found, in the online version, at doi: https://doi.org/10.1016/j.cireng.2023.10.004. APPENDIX B: [{(Appendix A)}] Supplementary data The following is Supplementary data to this article.
November 17, 2023: Cirugia española
https://read.qxmd.com/read/37853412/can-3d-imaging-modeling-recognize-functional-tissue-and-predict-liver-failure-a-retrospective-study-based-on-3d-modelling-of-the-major-hepatectomies-after-hepatic-modulation
#8
JOURNAL ARTICLE
Emilio Vicente, Yolanda Quijano, Hipolito Duran, Eduardo Diaz, Isabel Fabra, Luis Malave, Pablo Ruiz, Giada Pizzuti, Chiara Naldini, Giovanni De Nobili, Riccardo Caruso, Valentina Ferri
BACKGROUND: Thanks to the introduction of radiomics, 3d reconstruction can be able to analyse tissues and recognise true hypertrophy from non-functioning tissue in patients treated with major hepatectomies with hepatic modulation.The aim of this study is to evaluate the performance of 3D Imaging Modelling in predict liver failure. METHODS: Patients submitted to major hepatectomies after hepatic modulation at Sanchinarro University Hospital from May 2015 to October 2019 were analysed...
October 18, 2023: BMC Surgery
https://read.qxmd.com/read/37848689/pure-laparoscopic-associating-liver-partition-and-portal-vein-ligation-for-staged-hepatectomy-alpps-for-a-giant-hepatocellular-carcinoma-%C3%A2-15%C3%A2-cm-abutting-the-liver-hilum
#9
JOURNAL ARTICLE
Zhongkai Wang, Wei-Liang Loh, Brian K P Goh
INTRODUCTION: This video manuscript presents a unique case of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure performed in case of a giant hepatocellular carcinoma (> 15 cm in size) whereby both stages were completed via the pure laparoscopic approach. METHODS: This case was performed in our institution in 2022. All data were obtained from the patient's records in our prospectively maintained database...
October 17, 2023: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/37749572/extreme-hepatectomy-with-modified-alpps-in-a-rat-model-gradual-portal-vein-restriction-associated-with-hepatic-artery-restriction
#10
JOURNAL ARTICLE
Xiaoqin He, Yuefeng Zhang, Peng Ma, Zuo Mou, Wei Wang, Kaihuan Yu, Weixing Wang
BACKGROUND & AIM: Associating liver partition and portal vein ligation (PVL) for staged hepatectomy (ALPPS) is a creative strategy for enlarging the future liver remnant (FLR) and increasing the tumor resectability rate. However, the indications for ALPPS must have a certain limit when the FLR is too small. We aimed to establish a modified ALPPS model with more widen applicability in rats. METHODS: An extreme ALPPS model was established in rodents with only a 6...
September 25, 2023: BMC Surgery
https://read.qxmd.com/read/37600287/efficacy-of-technical-modifications-to-the-associating-liver-partition-and-portal-vein-ligation-for-staged-hepatectomy-alpps-procedure-a-systematic-review-and-meta-analysis
#11
JOURNAL ARTICLE
Elias Khajeh, Ali Ramouz, Arash Dooghaie Moghadam, Ehsan Aminizadeh, Omid Ghamarnejad, Sadeq Ali-Hassan-Al-Saegh, Ahmed Hammad, Saeed Shafiei, Sepehr Abbasi Dezfouli, Arash Nickkholgh, Mohammad Golriz, Gil Goncalves, Ricardo Rio-Tinto, Carlos Carvalho, Katrin Hoffmann, Pascal Probst, Arianeb Mehrabi
UNLABELLED: To compare the outcomes of modified-Associating Liver Partition and Portal vein Ligation for Staged hepatectomy (ALPPS) techniques with those of conventional-ALPPS. BACKGROUND: ALPPS is an established technique for treating advanced liver tumors. METHODS: PubMed, Web of Science, and Cochrane databases were searched. The outcomes were assessed by single-arm and 2-arm analyses. RESULTS: Seventeen studies containing 335 modified-ALPPS patients were included in single-arm meta-analysis...
December 2022: Annals of surgery open: perspectives of surgical history, education, and clinical approaches
https://read.qxmd.com/read/37562278/mixed-reality-combined-with-alpps-for-colorectal-liver-metastases-a-case-report
#12
Darick Fidan, Genadi Mero, Laura Ioana Mazilescu, Theodor Heuer, Gernot Maximilian Kaiser
INTRODUCTION: Improvement of treatments for patients suffering from colorectal carcinoma and extended liver metastases has increased the overall survival and enables more patients to undergo surgical therapy. If the future liver remnant (FLR) is expected to be low, Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) is a potential treatment with high feasibility and an increase in overall survival. The evolving mixed reality technology could support hepatobiliary surgery...
August 2023: International Journal of Surgery Case Reports
https://read.qxmd.com/read/37403000/the-value-of-intraoperative-dynamic-liver-function-test-icg-in-predicting-postoperative-complications-in-patients-undergoing-staged-hepatectomy-a-pilot-study
#13
JOURNAL ARTICLE
Karoline Horisberger, Fabian Rössler, Christian E Oberkofler, Dimitri Raptis, Henrik Petrowsky, Pierre-Alain Clavien
PURPOSE: To assess the predictive value of intraoperative indocyanine green (ICG) test in patients undergoing staged hepatectomy. METHODS: We analyzed intraoperative ICG measurements of future liver remnant (FLR), preoperative ICG, volumetry, and hepatobiliary scintigraphy in 15 patients undergoing associated liver partition and portal vein ligation for staged hepatectomy (ALPPS). Main endpoints were the correlation of intraoperative ICG values to postoperative complications (Comprehensive Complication Index (CCI®)) at discharge and 90 days after surgery, and to postoperative liver function...
July 5, 2023: Langenbeck's Archives of Surgery
https://read.qxmd.com/read/37345188/laparoscopic-right-hemihepatectomy-after-future-liver-remnant-modulation-a-single-surgeon-s-experience
#14
JOURNAL ARTICLE
Tijs J Hoogteijling, Jasper P Sijberden, John N Primrose, Victoria Morrison-Jones, Sachin Modi, Giuseppe Zimmitti, Marco Garatti, Claudio Sallemi, Mario Morone, Mohammad Abu Hilal
BACKGROUND: Laparoscopic right hemihepatectomy (L-RHH) is still considered a technically complex procedure, which should only be performed by experienced surgeons in specialized centers. Future liver remnant modulation (FLRM) strategies, including portal vein embolization (PVE), and associating liver partition and portal vein ligation for staged hepatectomy (ALPPS), might increase the surgical difficulty of L-RHH, due to the distortion of hepatic anatomy, periportal inflammation, and fibrosis...
May 21, 2023: Cancers
https://read.qxmd.com/read/37337927/associating-liver-partition-and-portal-vein-ligation-for-staged-hepatectomy-as-bridging-therapy-for-liver-transplantation-in-an-infant-with-an-advanced-hepatic-rhabdoid-tumor
#15
Yasunori Uesato, Shinichiro Ono, Futoshi Kawamata, Seisuke Sakamoto, Masaaki Kuda, Mureo Kasahara, Mitsuhisa Takatsuki
BACKGROUND: Malignant rhabdoid tumors (MRTs) are rare, aggressive tumors that mainly affect children and currently lack effective chemotherapeutic regimens. Liver MRTs are particularly challenging to manage due to the difficulty of performing one-stage liver resection, and preemptive liver transplantation is associated with high recurrence rates. However, the associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) technique offers a promising surgical approach for advanced-stage liver tumors where conventional liver resection is not feasible...
June 20, 2023: Pediatric Transplantation
https://read.qxmd.com/read/37333827/a-bibliometric-and-visualized-analysis-of-preoperative-future-liver-remnant-augmentation-techniques-from-1997-to-2022
#16
JOURNAL ARTICLE
Sihao Du, Zhenshun Wang, Dongdong Lin
BACKGROUND: The size and function of the future liver remnant (FLR) is an essential consideration for both eligibility for treatment and postoperative prognosis when planning surgical hepatectomy. Over time, a variety of preoperative FLR augmentation techniques have been investigated, from the earliest portal vein embolization (PVE) to the more recent Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) and liver venous deprivation (LVD) procedures. Despite numerous publications on this topic, no bibliometric analysis has yet been conducted...
2023: Frontiers in Oncology
https://read.qxmd.com/read/37124694/associating-liver-partition-and-portal-vein-ligation-or-combined-transarterial-chemo-embolisation-and-portal-vein-embolisation-for-staged-hepatectomy-for-hbv-related-hepatocellular-carcinoma
#17
EDITORIAL
Paschalis Gavriilidis, Timothy M Pawlik, Tomer Meirson, Daniel Azoulay
No abstract text is available yet for this article.
April 10, 2023: Hepatobiliary Surgery and Nutrition
https://read.qxmd.com/read/37124693/alpps-versus-portal-vein-embolization-for-hepatitis-b-virus-associated-hepatocellular-carcinoma-a-delicate-balance-between-volume-and-morbidity
#18
EDITORIAL
Víctor Lopez-Lopez, Kohei Miura, Asuncion Lopez-Conesa, Roberto Brusadin, Alvaro Navarro, Ricardo Robles-Campos
No abstract text is available yet for this article.
April 10, 2023: Hepatobiliary Surgery and Nutrition
https://read.qxmd.com/read/37124688/a-novel-comprehensive-alpps-preoperative-risk-assessment-capra-score-is-beneficial-in-creating-a-treatment-strategy-for-advanced-liver-malignancy
#19
EDITORIAL
Kensuke Yamamura, Toru Beppu, Tatsunori Miyata, Hirohisa Okabe, Katsunori Imai, Takatoshi Ishiko
No abstract text is available yet for this article.
April 10, 2023: Hepatobiliary Surgery and Nutrition
https://read.qxmd.com/read/37124686/associating-liver-partition-and-portal-vein-ligation-for-staged-hepatectomy-alpps-a-fine-balance
#20
EDITORIAL
Kai Tai Derek Yeung, Mikael H Sodergren
No abstract text is available yet for this article.
April 10, 2023: Hepatobiliary Surgery and Nutrition
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