P Faulcon, F Portier, B Biacabe, P Bonfils
We report here a series of 118 patients (79% women) who developed dysomia after acute rhinitis. Mean age was 59 years. Mean follow-up after the initial rhinal episode was 36 months. The dominant olfactory disorder was anosmia (71% of the patients) and dysgeusia in 71%. The prognosis of anosmia was poor as it persisted in 50% of the patients. Six patients (5%) recovered normal olfaction after a delay of 11 months. Partial recovery was observed in 45% of the patients with a mean 14-month delay. Recovery of olfaction was thus observed within the first year...
December 1999: Annales D'oto-laryngologie et de Chirurgie Cervico Faciale
P Bonfils, F L Corre, B Biacabe
Chemosensory dysfunction is relatively common. This article describes a series of 306 patients who presented with anosmia. We divided olfactory disorders into those associated with interruption of the transport of stimulus and those associated with damage to either peripheral or central nervous system structures. Nasal and paranasal sinus disease (transport interruption) was found to be causative in 67% of patients presenting with anosmia. These patients are generally 45 years old, the loss of olfaction is progressive and associated with additional nasal symptoms...
September 1999: Annales D'oto-laryngologie et de Chirurgie Cervico Faciale
T Romo, A P Sclafani, A N Falk, P H Toffel
Septal perforation is an avoidable complication of septal surgery, but it can also occur because of a variety of traumatic, iatrogenic, caustic, or inflammatory reasons. Symptoms usually are related to disruption of the normally laminar flow of air through the nasal passages. Crusting, bleeding, parosmia, and neuralgia can develop, leading the patient to seek medical care. When local hygiene and conservative care are unsuccessful in relieving symptoms, closure of the perforation is considered. Repair is often difficult because of the limited exposure and limited amounts of friable mucosa with impaired vascular supply...
January 1999: Plastic and Reconstructive Surgery
B Rydzewski, W Sułkowski, M Miarzyńska
The evaluation of olfaction is not only widely applied and undeniably valuable in clinical diagnostics but it is also of interest to industrial medicine. It should be borne in mind that in certain workplaces, particularly in the chemical industry, the olfactory receptor has to act as an organ which warns the worker against threatening intoxication, and this is possible only when it functions properly. Cadmium, as a highly toxic metal, found widely in industry and in the environment, is frequently included in the list of chemicals known to cause olfactory impairment...
1998: International Journal of Occupational Medicine and Environmental Health
R L Doty, D M Yousem, L T Pham, A A Kreshak, R Geckle, W W Lee
BACKGROUND: The ability to smell is commonly altered by head trauma (HT). However, the nature, prevalence, prognosis, and etiology of such alterations are poorly understood. OBJECTIVES: To quantitatively determine the degree of olfactory function in patients with HT-related chemosensory complaints and to examine the influences of age, sex, HT severity, time since HT, and other variables on such function. Also, to use quantitative magnetic resonance imaging (MRI) to establish whether and to what degree damage to the olfactory bulbs and tracts, frontal lobes, and temporal lobes occurs...
September 1997: Archives of Neurology
H Hamazaki, H Hasegawa, A Horiuchi, H Teshima, A Hiraoka, T Masaoka, K Nasu, H Uchino, N Tatsumi, N Inoue, T Kageyama, H Kawagoe, M Tukaguchi, S Hukuhara, T Takahashi, H Takatsuka, A Kanamaru, E Kakishita, K Nagai, H Hara, Y Kanayama, H Sugiyama, T Kitani
We investigated the therapeutic efficacy and safety of cefpirome sulfate (CPR) in treatment of hematopoietic disorder-associated infections. A total of 219 patients were admitted to 12 hospitals of Hanshin Study Group of hematopoietic disorders and infections between April 1994 and March 1996 and were enrolled in this study. Most patients received intravenously infused CPR at a dose of 1 or 2 g twice a day for 3 days or more. Twenty nine patients dropped out or were excluded and remaining 190 patients were adopted for the evaluation...
January 1997: Japanese Journal of Antibiotics
S Nordin, C Murphy, T M Davidson, C Quiñonez, A A Jalowayski, D W Ellison
The prevalence of parosmia and phantosmia among 363 chemosensory and nasal/sinus patients was studied, as was the accuracy with which our clinical questionnaire could assess these dysfunctions. We then investigated whether patients with parosmia or phantosmia, matched for odor intensity, perform poorer on odor identification than do patients with no dysosmia. More than 40% of the study group evidenced either parosmia (18.7%) and/or phantosmia (25.6%), a finding that suggests that more attention should be paid by the medical practitioner in addressing qualitative olfactory dysfunction...
June 1996: Laryngoscope
H Auffermann, G Gerull, F Mathe, D Mrowinski
Objective diagnosis of olfaction can be performed by registration of cortical olfactory evoked potentials (OEP) and of contingent negative variation (CNV). The CNV is a negative voltage developing at the vertex after discrimination of one of two smells while the patient is expecting a second stimulus. By an adequate procedure, including a long time window for averaging (2.56 seconds) with appropriate filters, the two tests can be performed simultaneously in a single session of less than 10 minutes. Anosmia is determinable by both OEP and CNV, although CNV shows less variability...
January 1993: Annals of Otology, Rhinology, and Laryngology
G Matern, C Matthias, D Mrowinski
Normally, the sense of smell is assessed by means of traditional subjective tests (sniff test, gustatory smell test, and trigeminus test). When results are inconclusive, an objective smell test is indicated. Simultaneously registering olfactory evoked potentials (OEP) and contingent negative variation (CNV) permits evaluation of both odor perception and odor discrimination. We can even objectively assess the false olfactory sensations in parosmia patients who are unable to discriminate between different odors...
February 1995: Laryngo- Rhino- Otologie
G S Barolin, S Kascha, H Siegl
No abstract text is available yet for this article.
June 1980: Der Nervenarzt
G Gerull, G Mielke, D Mrowinski
In addition to olfactory evoked responses (Fig. 1a) the vertex-negative voltage shift was registered in 20 normal adults. Fig. 2 shows this potential for an olfactory indicative stimulus followed by a tone burst or flash sequence, which are stopped by the test person's manual reaction. In Fig. 3 two alternating odorous stimuli are presented, one of which is followed by the tone. The selective expectancy wave is followed by the tone. The selective expectancy wave is only built up by the marked olfactory stimulus...
September 1981: EEG-EMG Zeitschrift Für Elektroenzephalographie, Elektromyographie und Verwandte Gebiete
K Zilstorff
No abstract text is available yet for this article.
November 1966: Journal of Laryngology and Otology
J M Bouchet
No abstract text is available yet for this article.
January 1972: Annales D'oto-laryngologie et de Chirurgie Cervico Faciale
R Azemar
No abstract text is available yet for this article.
January 1969: Journal Français D'oto-rhino-laryngologie, Audio-phonologie et Chirurgie Maxillo-faciale
R Fikentscher, C Rasinski
The paper proposes the definition and technical terms with greater precision for the description of qualitative smelling disturbances. Thereafter, parosmias are relevant only for the ENT specialist. Their further classification seems to be unnecessary or even false. These parosmias are always described to be troublesome for the patient since he feels the abnormality of the olfactory sensation. Thus, a clear distinction against phantosmias (olfactory hallucinations) and pseudoosmias (olfactory illusions) is given...
December 1986: Laryngologie, Rhinologie, Otologie
T Kinjo, J Mukawa, K Miyagi, E Takara, S Mekaru, Y Ishikawa
A 41-year-old male patient was admitted in our Ryukyu University Hospital complaining of parosmia. He had a history of miliary tuberculosis 21 years ago. Neurologically he showed left anosmia and hyperreflexia of the right upper extremity. Plain skull X-P and CT scan revealed a calcified mass, 25mm in diameter, at the left frontal base. In MRI, the mass showed isointensity using the T1 weighted inversion recovery sequence and heterogenously low intensity using the T2 weighted spin echo sequence. Surgery was performed by bifrontal craniotomy...
May 1988: No Shinkei Geka. Neurological Surgery
R Fikentscher, H Gudziol, B Roseburg
The smell and taste disorders are defined in terms due to two principles - the type and site of lesion. The quantitative dysosmias (anosmia, hyposmia, hyperosmia) correspond to the quantitative dysgeusias (ageusia, hypogeusia, hypergeusia) and the qualitative dysosmias (parosmia, pseudo-osmia, phantosmia, agnosmia) correspond to the qualitative dysgeusias (parageusia, pseudogeusia, phantogeusia, agnogeusia). Due to the site of lesion we can differentiate between respiratory, epithelial, combined, neural, and central dysosmias as well as epithelial, neural, and central dysgeusias...
July 1987: Laryngologie, Rhinologie, Otologie
G S Rutherfoord, B Mathew
Xanthogranulomas of the choroid plexus are usually asymptomatic. We present a short case report of a 60-year-old male whose symptoms of parosmia and parageusia have been relieved following surgical removal of a xanthogranuloma situated in the right lateral ventricle. Previous case reports and correlation of symptomatology and pathology are discussed.
1987: British Journal of Neurosurgery
R Fikentscher, H Seeber
Olfactometric fitness examinations in relation to the place of work are required since the olfactory organ has support and protective functions. Smelling disorders result at work from trauma, hypersensitivity, acute and chronic intoxications, but most frequently from chemical and physical substances taken up by inhalation. They are different due to their expression (slight hyposmia till to anosmia, parosmia), latency, localization (respiratory, epithelial, nerval, central), and a combination with other disorders...
February 1989: Zeitschrift Für die Gesamte Hygiene und Ihre Grenzgebiete
A E Scott
Chemosensory problems can have major consequences for those patients who develop them. Although more than 200 conditions and 40 medications have been linked to taste and smell disorders, for most patients the cause will fall into one of the following categories: nasal/sinus disease, idiopathic, postviral URI, and head trauma. Careful attention to clinical characteristics will aid immensely in the diagnosis. Parosmias, dysgeusias and the burning mouth syndrome are symptoms that deserve special consideration.
April 1989: Ear, Nose, & Throat Journal
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