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hydrops corneal

Angelika L Erwin, Robert J Desnick
Congenital erythropoietic porphyria (CEP) is a rare autosomal recessive disorder characterized by photosensitivity and by hematologic abnormalities in affected individuals. CEP is caused by mutations in the uroporphyrinogen synthase (UROS) gene. In three reported cases, CEP has been associated with a specific X-linked GATA1 mutation. Disease-causing mutations in either gene result in absent or markedly reduced UROS enzymatic activity. This in turn leads to the accumulation of the non-physiologic and photoreactive porphyrinogens, uroporphyrinogen I and coproporphyrinogen I, which damage erythrocytes and elicit a phototoxic reaction upon light exposure...
December 27, 2018: Molecular Genetics and Metabolism
Mohammad Soleimani, Reza Mirshahi, Seyed Ali Tabatabaei, Bita Momenaei, Mirataollah Salabati, Mohammad Reza Ghomi
PURPOSE: To introduce a new surgical technique for the localization of corneal bulla to drain a massive corneal hydrops. METHODS: Four consecutive cases with acute large protruded hydrops were selected. A limbal paracentesis was made via 15° blade. Afterward, trypan blue with a concentration of 0.1% was injected into the anterior chamber. Upon pooling trypan blue in the bulla, the surgeon immediately marked the primary site of stromal staining before further spreading of the dye...
December 12, 2018: European Journal of Ophthalmology
Shreesha Kumar Kodavoor, Bijita Deb, Dandapani Ramamurthy
Purpose: To evaluate functional and anatomical outcome in patients undergoing deep anterior lamellar keratoplasty (DALK) with intraoperative Descemet's membrane (DM) perforation (macro and micro). Methods: A retrospective cross sectional study (January 2009 to December 2015) of sixteen eyes of sixteen patients which included nine patients of advanced keratoconus (KC), two patients with paracentral DM scarring post hydrops, KC with Bowman's membrane scarring, macular corneal dystrophy and one patient of advanced Pellucid Marginal Degeneration (PMD)...
November 2018: Indian Journal of Ophthalmology
Parul C Gupta, Jitender Jinagal, Amit Gupta, Jagat Ram
No abstract text is available yet for this article.
October 2018: Indian Journal of Ophthalmology
G Schießl, S Suffo, G Milioti, B Seitz
We report on a 52-year-old male patient presenting with unilateral loss of vision of one week's duration. Pellucid marginal corneal degeneration was known. Slit lamp examination showed pronounced corneal edema as defined by acute corneal hydrops. After inferior preventive YAG iridotomy through clear cornea, intracameral air injection was performed. Deep stromal 10-0 nylon sutures were applied along the Descemet's membrane tear. The next day, the corneal edema had already begun to decrease.
September 18, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Kirithika Muthusamy, Stephen Tuft
Brittle cornea syndrome (BCS1 OMIM #229200, BCS2 #614170) is a rare autosomal recessive condition characterised by diffuse thinning and fragility of the cornea. Affected individuals are at risk of globe rupture and blindness after relatively minor eye trauma. We describe a 9-year-old girl with BCS1, already blind in one eye following trauma, who had a 14 mm diameter corneoscleral onlay graft to her contralateral eye to reduce gross irregular corneal astigmatism and potentially to reduce further risk from accidental injury...
August 16, 2018: BMJ Case Reports
Soosan Jacob, Smita Narasimhan, Amar Agarwal, Jambulingam Sambath, Govindharaj Umamaheshwari, Areeckal Incy Saijimol
PURPOSE: To report primary treatment of acute corneal hydrops (CH) with a modified technique of predescemetic deep anterior lamellar keratoplasty (pdDALK). METHODS: This prospective interventional case series included 9 eyes with acute CH that underwent pdDALK as primary treatment. Technique modifications included a bevel-up needle, creating tissue emphysema as a guide for dissection, using small aliquots of air directed away from break, manual deeper dissection using a blunt dissector, centripetal dissection leaving the area of Descemet membrane (DM) break for last, retention of minimal stroma above DM tear, and tamponade of DM tear with air in the anterior chamber...
October 2018: Cornea
Andrew M J Turnbull, Abdo Karim Tourkmani, Ramez Barbara, Parwez N Hossain, David F Anderson, Aris Konstantopoulos
No abstract text is available yet for this article.
August 2018: Cornea
Assaf Hilely, Guy Kleinmann
PURPOSE: To report a rare case of spontaneous corneal perforation after hydrops in keratoconus patients who suffer from familial Mediterranean fever and was treated systemically with Colchicine. METHODS: Case report. RESULTS: We report a case of a 30-year-old male with keratoconus and familial Mediterranean fever treated with colchicine, presented with acute hydrops in his left eye, which progressed to a spontaneous corneal perforation. Attempts to treat the perforation with cyanoacrylate glue failed, and he underwent penetrating keratoplasty with an excellent visual outcome...
April 30, 2018: International Ophthalmology
Korine van Dijk, Jack S Parker, Lamis Baydoun, Abbas Ilyas, Isabel Dapena, Esther A Groeneveld-van Beek, Gerrit R J Melles
PURPOSE: The purpose of this study was to evaluate the 5-year clinical results of isolated Bowman layer (BL) transplantation in the treatment of advanced keratoconus. METHODS: In this prospective, single-center, interventional case series at a tertiary referral center, 20 eyes of 17 patients with advanced keratoconus underwent BL transplantation, i.e. an isolated Bowman layer graft was positioned into a manually dissected mid-stromal pocket. Scheimpflug-based corneal tomography measurements, best corrected spectacle and contact lens visual acuities (BSCVA and BCLVA), endothelial cell density, and complications were evaluated up to 5 years after surgery...
June 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Akilesh Gokul, Hans R Vellara, Dipika V Patel
Advances in anterior segment imaging have enhanced our ability to detect keratoconus in its early stages and characterize the pathologic changes that occur. Computerized corneal tomography has elucidated the alterations in shape of the anterior and posterior corneal surfaces and alterations in thickness as the disease progresses. Automated screening indices such as the keratoconus screening index were developed to assist in detecting keratoconus in suspicious cases. In vivo assessment of keratoconic corneas has revealed that compromised corneal biomechanics can now be measured clinically...
March 2018: Clinical & Experimental Ophthalmology
Brittany N Schlesener, Erin M Scott, Lucien V Vallone
A 1-year-old, female spayed, domestic shorthair cat presented for blepharospasm of the right eye. Slit-lamp biomicroscopic examination showed focal corneal ulceration and presumptive keratomalacia of the right eye. Examination of the left eye was normal apart from a focal endothelial opacity. Within the first 24 h of medical management, the right eye developed marked corneal edema and globular anterior protrusion of the corneal surface consistent with feline acute corneal hydrops (FACH). Surgical management consisted of a bridge conjunctival graft, nictitating membrane flap, and temporary tarsorrhaphy...
July 2018: Veterinary Ophthalmology
Manisha Acharya, Abhishek Dave, Umang Mathur
A 15-year-old boy was diagnosed with Mooren's ulcer in the right eye at our cornea clinic. On treatment, he developed acute corneal hydrops, and the vision in the right eye dropped to perception of light. The patient was treated with intracameral injection of perfluoropropane (C3F8) gas which resulted in complete resolution of corneal edema. Contact lens fitting yielded a good visual outcome with a best-corrected visual acuity of 20/80. To the best of our knowledge, this is the only case reporting the occurrence of acute corneal hydrops in a child with Mooren's ulcer...
April 2017: Middle East African Journal of Ophthalmology
Berthold Seitz, Achim Langenbucher, Tobias Hager, Edgar Janunts, Moatasem El-Husseiny, Nora Szentmáry
BACKGROUND: In case of keratoconus, rigid gas-permeable contact lenses as the correction method of first choice allow for a good visual acuity for quite some time. In a severe stage of the disease with major cone-shaped protrusion of the cornea, even specially designed keratoconus contact lenses are no more tolerated. In case of existing contraindications for intrastromal ring segments, corneal transplantation typically has a very good prognosis. METHODS: In case of advanced keratoconus - especially after corneal hydrops due to rupture of Descemet's membrane - penetrating keratoplasty (PKP) still is the surgical method of first choice...
2017: Open Ophthalmology Journal
Elmer Y Tu
PURPOSE: To report successful management of a case of persistent keratoconus-related hydrops with a Descemet membrane endothelial keratoplasty (DMEK) patch graft. METHODS: A case of corneal hydrops persisting for 7 months treated with DMEK was identified. The following information was collected: demographic data, surgical indications, clinical course, diagnostic tests, and clinical outcome. RESULTS: A 55-year-old patient with an established diagnosis of keratoconus was followed for 7 months without improvement in his acute corneal hydrops...
December 2017: Cornea
Jorge L Alió Del Barrio, Olena Al-Shymali, Jorge L Alió
PURPOSE: To describe the outcomes of femtosecond laser-assisted tuck-in penetrating keratoplasty as a single-step surgical procedure for visual and anatomical rehabilitation of patients with severe keratoglobus (KTG) and endothelial damage. METHODS: Two eyes of a 7-year-old patient with bilateral severe KTG and previous corneal hydrops were operated. Assisted by the femtosecond laser, both donor and recipient corneas were prepared. An 8.5-mm full-thickness donor tissue with a peripheral partial-thickness rim of 1...
September 2017: Cornea
Virgilio Galvis, Alejandro Tello, Marcela F Cianci, Luis Carlos Escaf, M Margarita Parra
A 15-year-old male patient with corneal hydrops and a giant intrastromal cleft (pseudocyst) successfully received medical treatment with topical prednisolone, hypertonic saline solution and ocular hypotensive eyedrops. Anterior segment optical coherence tomography (OCT) was used as an auxiliary tool for assessing the response to treatment during follow-up time (33 months).
August 2018: International Ophthalmology
S Harchali, S Azenoud, S Elmerrouni, M Zarrouki, M Elyadari, E Abdellah, A Berraho
No abstract text is available yet for this article.
June 1, 2017: Journal Français D'ophtalmologie
Praveen Subudhi, Zahiruddin Khan, B Nageswar Rao Subudhi, Silla Sitaram
A 17-year-old boy presented with sudden loss of vision in the left eye (OS) for 3 days. He was diagnosed with acute hydrops following keratoconic progression in OS. The patient was initially started on topical medical therapy, including steroids and hypertonic eye drops; showing no signs of resolution. Hence, the patient was planned for full-thickness compressive corneal sutures. Four sutures were placed along the central oedematous area covering the area of ruptured Descemet's membrane. Signs of resolution were noticed by 1st week and there was complete resolution of oedema by 3rd post-op week...
May 4, 2017: BMJ Case Reports
Matthias Fuest, Jodhbir S Mehta
Corneal hydrops affects approximately 2.5% of keratoconus (KC) cases, predominantly young males approximately 25 years of age with steep cones. Often, patients are left with a vision-reducing corneal scar frequently necessitating surgical treatment. Penetrating keratoplasty (PK) has worse survival outcomes in hydrops than in general KC cases. Deep anterior lamellar keratoplasty (DALK) is a nonpenetrating technique believed to achieve equal or better outcomes in visual acuity, graft survival, endothelial rejection rates, and endothelial cell survival in comparison with PK, while maintaining globe integrity and the patients' Descemet membrane (DM) and endothelium...
March 2018: Eye & Contact Lens
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