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Keywords Elevated troponin in exercise ...

Elevated troponin in exercise induced

https://read.qxmd.com/read/34459237/determinants-of-interindividual-variation-in-exercise-induced-cardiac-troponin-i-levels
#21
JOURNAL ARTICLE
Magnus Bjørkavoll-Bergseth, Christine Bjørkvik Erevik, Øyunn Kleiven, Thijs M H Eijsvogels, Øyvind Skadberg, Vidar Frøysa, Tomasz Wiktorski, Bjørn Auestad, Thor Edvardsen, Kristin Moberg Aakre, Stein Ørn
Background Postexercise cardiac troponin levels show considerable interindividual variations. This study aimed to identify the major determinants of this postexercise variation in cardiac troponin I (cTnI) following 3 episodes of prolonged high-intensity endurance exercise. Methods and Results Study subjects were recruited among prior participants in a study of recreational cyclists completing a 91-km mountain bike race in either 2013 or 2014 (first race). In 2018, study participants completed a cardiopulmonary exercise test 2 to 3 weeks before renewed participation in the same race (second race)...
September 7, 2021: Journal of the American Heart Association
https://read.qxmd.com/read/34021921/circulating-micrornas-after-a-24-h-ultramarathon-run-in-relation-to-muscle-damage-markers-in-elite-athletes
#22
JOURNAL ARTICLE
Emeric Chalchat, Keyne Charlot, Sebastian Garcia-Vicencio, Pierre Hertert, Stéphane Baugé, Stéphanie Bourdon, Julie Bompard, Cédric Farges, Vincent Martin, Cyprien Bourrilhon, Julien Siracusa
Ultra-endurance sports are growing in popularity but can be associated with adverse health effects, such as exercise-induced muscle damage (EIMD), which can lead to exertional rhabdomyolysis. Circulating microRNAs (miRNAs) may be useful to approach the degree of EIMD. We aimed to (1) investigate the relevance of circulating miRNAs as biomarkers of muscle damage and (2) examine the acute response of skeletal/cardiac muscle and kidney biomarkers to a 24-h run in elite athletes. Eleven elite athletes participated in the 24-h run World Championships...
September 2021: Scandinavian Journal of Medicine & Science in Sports
https://read.qxmd.com/read/33959263/cardiac-stunning-during-haemodialysis-the-therapeutic-effect-of-intra-dialytic-exercise
#23
COMMENT
Scott McGuire, Elizabeth J Horton, Derek Renshaw, Klaris Chan, Alfonso Jimenez, Helen Maddock, Nithya Krishnan, Gordon McGregor
BACKGROUND: Cardiovascular risk is elevated in end-stage renal disease. Left ventricular (LV) dysfunction is linked to repetitive transient ischaemia occurring during haemodialysis (HD). Cardiomyocyte ischaemia results in 'cardiac stunning', evidenced by regional wall motion abnormalities (RWMAs). Ischaemic RWMA have been documented during HD resulting in maladaptive cardiac remodelling and increased risk of heart failure. Intra-dialytic exercise is well tolerated and can improve quality of life and functional capacity...
May 2021: Clinical Kidney Journal
https://read.qxmd.com/read/33841187/kinetics-moderators-and-reference-limits-of-exercise-induced-elevation-of-cardiac-troponin-t-in-athletes-a-systematic-review-and-meta-analysis
#24
Feifei Li, Will G Hopkins, Xuejing Wang, Julien S Baker, Jinlei Nie, Junqiang Qiu, Binh Quach, Kun Wang, Longyan Yi
Background: Kinetics, moderators and reference limits for exercise-induced cardiac troponin T (cTnT) elevations are still unclear. Methods: A systematic review of published literature was conducted adhering to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. Studies reporting high-sensitivity cardiac troponin T (hs-cTnT) concentrations before and after a bout of exercise in athletes were included and analyzed. The final dataset consisted of 62 estimates from 16 bouts in 13 studies of 5-1,002 athletes (1,421 in total)...
2021: Frontiers in Physiology
https://read.qxmd.com/read/33773099/cardiac-performance-in-patients-hospitalized-with-covid-19-a-6%C3%A2-month-follow-up-study
#25
JOURNAL ARTICLE
Antoine Fayol, Marine Livrozet, Pierre Boutouyrie, Hakim Khettab, Maureen Betton, Victoria Tea, Anne Blanchard, Rosa-Maria Bruno, Jean-Sébastien Hulot
AIMS: Myocardial injury is frequently observed in patients hospitalized with coronavirus disease 2019 (COVID-19) pneumonia. Different cardiac abnormalities have been reported during the acute COVID-19 phase, ranging from infra-clinic elevations of myocardial necrosis biomarkers to acute cardiac dysfunction and myocarditis. There is limited information on late cardiac sequelae in patients who have recovered from acute COVID-19 illness. We aimed to document the presence and quantify the extent of myocardial functional alterations in patients hospitalized 6 months earlier for COVID-19 infection...
June 2021: ESC Heart Failure
https://read.qxmd.com/read/33546247/a-combined-approach-for-health-assessment-in-adolescent-endurance-runners
#26
JOURNAL ARTICLE
Tomas K Tong, Julien S Baker, Fiona L Henriquez, Qingde Shi, Haifeng Zhang, Zhaowei Kong, Jinlei Nie
BACKGROUND: It has been shown that prolonged exhaustive exercise, such as half-marathon running, could lead to transient post-exercise elevation of cardiac troponins, increase in oxidative stress, and mild decline in renal function in adolescent athletes. With increases in sports participation involving young people, there has been much interest in pre and post health evaluations following exercise. Evaluations can be used to identify pre-existing health confounders and to examine any detrimental responses that may occur post exercise...
February 3, 2021: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/33535387/exercise-induced-release-of-cardiac-troponins-in-adolescent-vs-adult-swimmers
#27
JOURNAL ARTICLE
Rafel Cirer-Sastre, Francisco Corbi, Isaac López-Laval, Luis Enrique Carranza-García, Joaquín Reverter-Masià
To examine the exercise-induced release of cardiac troponin T (cTnT) in adolescent and adult swimmers. Thirty-two trained male (18 adolescents, 14 adults) swam at maximal pace in a 45 min distance trial, and blood samples were drawn before, immediately and 3 h after exercise for subsequent cTnT analysis and comparison. Having comparable training experience and baseline values of cTnT ( p = 0.78 and p = 0.13), adults exercised at lower absolute and relative intensity ( p < 0.001 and p < 0.001, respectively), but presented higher immediate cTnT after exercise than adolescents ( p < 0...
February 1, 2021: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/33031283/myocardial-bridging-an-unusual-cause-of-wellens-syndrome-a-case-report
#28
JOURNAL ARTICLE
Anamaria Avram, Valentin Chioncel, Suzana Guberna, Irina Cuciureanu, Radu Constantin Brezeanu, Catalina Liliana Andrei, Crina Sinescu
RATIONALE: Coronary chest pain is usually ischemic in etiology and has various electrocardiographic presentations. Lately, it has been recognized that myocardial bridging (MB) with severe externally mechanical compression of an epicardial coronary artery during systole may result in myocardial ischemia. Such a phenomenon can be associated with chronic angina pectoris, acute coronary syndromes (ACS), coronary spasm, ventricular septal rupture, arrhythmias, exercise-induced atrioventricular conduction blocks, transient ventricular dysfunction, and sudden death...
October 9, 2020: Medicine (Baltimore)
https://read.qxmd.com/read/32957761/-clinical-analysis-of-children-with-cardiac-syncope-caused-by-anomalous-origin-of-the-left-coronary-artery-from-the-right-sinus
#29
JOURNAL ARTICLE
Q R Li, Z Zhen, J Na, L Gao, Y L Cao, Y Yuan
Objective: To analysis the clinical characteristics and to summarize therapy experience of pediatric patients with cardiac syncope caused by anomalous origin of the left coronary artery from the right sinus (ALCA-R). Methods: We retrospectively analyzed the clinical data including clinical manifestations, myocardial injury biomarkers, radiological features, treatments and prognoses of pediatric patients with ALCA-R who were admitted to Beijing Children's Hospital from November 2015 to June 2018. Results: Four female patients were included in this analysis, age of onset was 7 to 14 years...
September 24, 2020: Zhonghua Xin Xue Guan Bing za Zhi
https://read.qxmd.com/read/32941818/relation-of-high-sensitivity-cardiac-troponin-i-elevation-with-exercise-to-major-adverse-cardiovascular-events-in-patients-with-coronary-artery-disease
#30
JOURNAL ARTICLE
Bruno B Lima, Muhammad Hammadah, Jeong Hwan Kim, Irina Uphoff, Amit Shah, Oleksiy Levantsevych, Zakaria Almuwaqqat, Kasra Moazzami, Samaah Sullivan, Laura Ward, Yan Sun, Michael Kutner, Yi-An Ko, David S Sheps, Agim Beshiri, Gillian Murtagh, J Douglas Bremner, Viola Vaccarino, Arshed A Quyyumi
High sensitive cardiac troponin I (hs-cTnI) increases with inducible myocardial ischemia in patients with coronary artery disease (CAD). We aimed to assess if the change in hs-cTnI levels with exercise stress testing is associated with major adverse cardiac events (MACE). A cohort of 365 (age 62 ± 9 years, 77% men) patients with stable CAD underwent 99mTc sestamibi myocardial perfusion imaging with treadmill testing. Plasma hs-cTnI level was measured at rest and at 45 min after stress. Multivariable Fine & Gray's subdistribution hazards models were used to determine the association between the change in hs-cTnI and MACE, a composite end point of cardiovascular death, myocardial infarction, and unstable angina requiring revascularization...
September 15, 2020: American Journal of Cardiology
https://read.qxmd.com/read/32680701/influence-of-maturational-status-in-the-exercise-induced-release-of-cardiac-troponin-t-in-healthy-young-swimmers
#31
JOURNAL ARTICLE
Rafel Cirer-Sastre, Alejandro Legaz-Arrese, Francisco Corbi, Isaac López-Laval, Keith George, Joaquín Reverter-Masia
OBJECTIVES: To determine the influence of maturational status on the release of cardiac troponin T (cTnT) induced by a bout of 30min, high-intensity, continuous exercise. DESIGN: Quasi-experimental, cross-sectional study. METHODS: Seventy male, young, well trained swimmers (age range 7-18 years, training experience 1-11 years) were classified by maturational stages: Tanner stage I (n=14), II (n=15), III (n=15), IV (n=13), and V (n=13). Participants underwent a distance-trial of 30min continuous swimming, and cTnT was measured before, immediately after and 3h after exercise...
July 3, 2020: Journal of Science and Medicine in Sport
https://read.qxmd.com/read/32642445/biochemical-and-toxicological-effect-of-diazepam-in-stress-induced-cardiac-dysfunctions
#32
JOURNAL ARTICLE
Fahad A Al-Abbasi, Vikas Kumar, Firoz Anwar
Diazepam is a medicine of the family benzodiazepine, used to treat various CNS disorders. To date, no study is available for biochemical analysis of diazepam in cardiac dysfunction. This study aimed to determine the effect of diazepam in stress-induced cardiac dysfunctions in rats. Male Wistar Albino rats were divided into four groups with six animals in each group for 90 days of the experimental protocol. Group1 served as a Normal Control (NC), Groups 2, as a Disease Control (DC), Group 3 as a Diazepam Control (DIC), and Group 4 as a Disease + Diazepam Treatment (DDT)...
2020: Toxicology Reports
https://read.qxmd.com/read/32065043/duration-of-elevated-heart-rate-is-an-important-predictor-of-exercise-induced-troponin-elevation
#33
JOURNAL ARTICLE
Magnus Bjørkavoll-Bergseth, Øyunn Kleiven, Bjørn Auestad, Trygve Eftestøl, Kay Oskal, Martin Nygård, Øyvind Skadberg, Kristin Moberg Aakre, Tor Melberg, Knut Gjesdal, Stein Ørn
Background The precise mechanisms causing cardiac troponin (cTn) increase after exercise remain to be determined. The aim of this study was to investigate the impact of heart rate (HR) on exercise-induced cTn increase by using sports watch data from a large bicycle competition. Methods and Results Participants were recruited from NEEDED (North Sea Race Endurance Exercise Study). All completed a 91-km recreational mountain bike race (North Sea Race). Clinical status, ECG, blood pressure, and blood samples were obtained 24 hours before and 3 and 24 hours after the race...
February 18, 2020: Journal of the American Heart Association
https://read.qxmd.com/read/32033112/cardiac-troponin-t-release-after-football-7-in-healthy-children-and-adults
#34
JOURNAL ARTICLE
Rafel Cirer-Sastre, Alejandro Legaz-Arrese, Francisco Corbi, Isaac López-Laval, Juan José Puente-Lanzarote, Vicenç Hernández-González, Joaquin Reverter-Masia
The objective of this study was to compare the release of cardiac troponin T (cTnT) after a football 7 match between two cohorts of children and adult players. Thirty-six male football players (children = 24, adult = 12) played a football 7 match, and cTnT was measured before, and 3 h after exercise. Concentrations of cTnT were compared between groups and time, and correlated with participants' characteristics, as well as internal and external exercise load. Cardiac troponin T was elevated in all participants ( p < 0...
February 4, 2020: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/31984126/impact-of-training-specificity-on-exercise-induced-cardiac-troponin-elevation-in-professional-athletes-a-pilot-study
#35
JOURNAL ARTICLE
Johan O Wedin, Nicolena S Nyberg, Anders E Henriksson
BACKGROUND: Release of cardiac biomarkers is common after strenuous endurance exercise, but data on intermittent exercise are scarce. It has not been investigated whether cardiac troponin elevation is influenced depending on the type of exercise that an athlete is adapted to perform. We hypothesized that intermittent but not continuous exercise induces cardiac troponin elevation in professional athletes adapted to high-intensity intermittent exercise. AIM: To examine how training specificity impacts high-sensitivity cardiac troponin T (hs-cTnT) release...
January 26, 2020: World Journal of Cardiology
https://read.qxmd.com/read/31975465/exercise-induced-release-of-troponin
#36
REVIEW
George A Stavroulakis, Keith P George
It is well established that regular physical activity reduces cardiovascular disease risk; however, numerous studies have demonstrated postexercise elevations in cardiac troponin (cTn), indicative of cardiac injury in apparently healthy individuals. The prevalence of these findings in different exercise settings and population groups, as well as potential underlying mechanisms and clinical significance of exercise-induced cTn release are not yet quite determined. The present review will discuss the cTn response to exercise in light of developing cTn assays and the correlation between postexercise cTn release and cardiac function...
January 24, 2020: Clinical Cardiology
https://read.qxmd.com/read/31791434/troponin-elevation-in-the-setting-of-exercise-induced-rhabdomyolysis-in-an-athletic-teenager
#37
JOURNAL ARTICLE
Jacqueline Rausa, Ira Shetty, Rohit S Loomba
Troponin levels are often obtained when chest pain is evaluated in the paediatric emergency department. Elevations in troponin levels can be due to different causes, and it is important to fully understand all of these possible causes to help streamline further evaluation and therapy. We present the case of a teenager who had two episodes of troponin elevation in the setting of rhabdomyolysis.
December 2019: Cardiology in the Young
https://read.qxmd.com/read/31708962/angiotensin-converting-enzyme-related-polymorphisms-on-inflammation-muscle-and-myocardial-damage-after-a-marathon-race
#38
JOURNAL ARTICLE
Ana Paula Rennó Sierra, Giscard Humberto Oliveira Lima, Elton Dias da Silva, Jaqueline Fernanda de Souza Maciel, Marino Pereira Benetti, Rodrigo Assunção de Oliveira, Patrícia Fátima de Oliveira Martins, Maria Augusta Pedanti Kiss, Nabil Ghorayeb, Philip Newsholme, João Bosco Pesquero, Maria Fernanda Cury-Boaventura
Muscle damage is one of the most important factors that affect muscle fatigue during endurance exercise. Recent evidence suggests that the renin-angiotensin system impacts on skeletal muscle wasting. The aim of this study was to determine association between the AGT Met235Thr, ACE I/D and BDKRB2 -9/+9 polymorphisms with inflammation, myocardial and muscle injury induced by endurance exercise. Eighty-one Brazilian male runners participated in this study and completed the International Marathon of Sao Paulo. Muscle and myocardial damage markers (alanine transaminase, ALT, aspartate transaminase, AST, lactic dehydrogenase, LDH, creatine kinase, CK, Troponin, pro BNP, myoglobin, and CK-MB) and inflammatory mediators (IL-6, IL-8, IL-10, IL12p70, IL1β, and TNF-α) were determined one day before, immediately after, one day after, and three days after the event...
2019: Frontiers in Genetics
https://read.qxmd.com/read/31690491/the-impact-of-exercise-modality-and-menstrual-cycle-phase-on-circulating-cardiac-troponin-t
#39
RANDOMIZED CONTROLLED TRIAL
Jinlei Nie, Haifeng Zhang, Zhaowei Kong, Cong Wang, Yang Liu, Qingde Shi, Keith George
OBJECTIVES: It is unclear whether exercise modality (moderate-intensity continuous [MCE]; high-intensity interval [HIE]) and menstrual cycle phase (follicular [FP]; luteal [LP]), individually or in combination, mediate the commonly observed exercise-induced elevation in cardiac troponin T (cTnT). This study examines cTnT responses to MCE and HIE during both the FP and LP. DESIGN: Randomised crossover study. METHODS: Seventeen healthy, eumenorrheic women completed four trials including MCE (60% VO2max steady-state cycling until 300kJ) and work-equivalent HIE (repeated 4-min cycling at 90% VO2max interspersed with 3-min rest) during both the FP and LP...
March 2020: Journal of Science and Medicine in Sport
https://read.qxmd.com/read/31673409/effects-of-one-week-different-intensity-endurance-exercise-on-cardiorespiratory-and-cardiometabolic-markers-in-junior-young-athletes
#40
JOURNAL ARTICLE
Gashaw Tesema, Mala George, Soumitra Mondal, D Mathivana
Background: Endurance training in varied intensity zones are more likely to show different adaptive responses. However, it is still unclear the intensity level of endurance exercise in junior young athletes that may promote increased markers for cardiorespiratory and cardiometabolic response. Therefore, we aimed to investigate the effect of 1 week different intensity endurance training on markers of cardiorespiratory and cardiometabolic response in young athletes. Methods: Thirty apparently healthy male young athletes averaging 19...
2019: BMJ Open Sport & Exercise Medicine
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