keyword
https://read.qxmd.com/read/37784831/complication-avoidance-of-reconstruction-implant-radiation-therapy-carit-a-retrospective-case-cohort-analysis
#21
JOURNAL ARTICLE
K Manouchehri, A Lokhandwala, A Jayatilaka, D Hadedeya, B P Yaremko, M Brackstone, F E Perera, T DeLyzer, A Grant, M I Lock
PURPOSE/OBJECTIVE(S): Patients are increasingly offered implant-based reconstruction prior to radiotherapy. However, it is unclear if the radiation treatment technique itself impacts upon toxicity. We performed this study to compare outcomes following implant-based reconstruction amongst breast cancer patients treated with a standard radiotherapy technique that irradiates the entire chest wall versus a novel technique which uses a smaller clinical target volume (CTV) to spare the implant...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784794/a-phase-ii-randomized-double-blind-placebo-controlled-study-of-the-safety-and-efficacy-of-a-caffeine-based-antifibrosis-cream-in-patients-with-breast-cancer-undergoing-radiation-therapy
#22
JOURNAL ARTICLE
C Hardy Abeloos, A Solan, C A Perez, O G Maisonet, B A Cronstein, R A Adler, J Goldberg, N K Gerber
PURPOSE/OBJECTIVE(S): Radiation induced fibrosis (RIF) is a common long term adverse event in patients undergoing post-mastectomy radiation therapy (PMRT) which can cause capsular contracture, implant loss, and reconstruction complications in women with implant-based breast reconstruction. At a molecular level, adenosine is a driver of RIF. Preclinical data have shown that pharmacologic blockade of the adenosine A2A Receptor (A2A R) in mice as well as an A2AR knockout mouse model prevented skin fibrosis associated with radiation injury...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784508/comparison-between-pre-pectoral-and-post-pectoral-implant-reconstruction-and-different-radiation-modalities-on-breast-reconstruction-complications
#23
JOURNAL ARTICLE
G E Naoum, A Niemierko, H Ababneh, M Ioakeim-Ioannidou, A G Taghian
PURPOSE/OBJECTIVE(S): Single Stage direct to implant (DTI) is a rising reconstruction approach. It has been speculated that prepectoral implant placement reduces reconstruction complications as well as using newer postmastectomy radiation (PMRT) modalities as protons. Largest series in this topic included 350 DTI patients with less than 30 patients receiving PMRT. MATERIALS/METHODS: We reviewed the charts of 2,187 patients (pts) who underwent mastectomy and reconstruction at our institution between 2000 and 2020...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784504/increased-complication-rates-with-proton-therapy-in-breast-cancer-patients-with-immediate-implant-based-reconstruction-single-institution-comparative-effectiveness-analysis
#24
JOURNAL ARTICLE
A G Taghian, G E Naoum, L Smith, M Ioakeim-Ioannidou, H Ababneh, S Macdonald, A Y Ho
PURPOSE/OBJECTIVE(S): To compare the impact of protons vs. photons on breast reconstruction complications, for patients (pts) receiving postmastectomy radiation (PMRT) with either single-stage direct-to-implant (DTI) or two-staged expander/implant (TE/I). MATERIALS/METHODS: We reviewed the charts of 578 pts who underwent immediate reconstruction followed by radiation at our institution between 2010 and 2020. Pts with implant-based reconstruction using either TE/I or DTI and PMRT delivery in the presence of the prosthesis were included...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37760901/adhesive-capsulitis-of-the-ankle-frozen-ankle-an-infrequent-syndrome
#25
REVIEW
Daniel Aguilar-Núñez, Dina Hamed-Hamed, María Aguilar-García, María Cuevas-Cervera, José Javier Pérez-Montilla, Ana González-Muñoz, Leo Pruimboom, Santiago Navarro-Ledesma
Adhesive capsulitis, characterized by progressive fibrosis, causes a gradual, painful loss of both active and passive articular motion, leading to the final contracture of the joint capsule. The condition commonly referred to as "frozen ankle" (FA), which Goldman was the first to use, relates to the ankle joint and is challenging to both diagnose and treat. Data acquired from people who suffer from this type of damage in other joints such as the shoulder, hip, and wrist also exists. Despite the fact that a well-defined model for the medical management of FA does not exist, a wide spectrum of local treatments, both surgical and non-surgical, exist...
September 5, 2023: Biomedicines
https://read.qxmd.com/read/37750141/effectiveness-of-early-physiotherapy-rehabilitation-approach-for-split-skin-grafting-post-burn-in-a-pediatric-patient
#26
Anushka Raipure, Shubhangi Patil, Heena Pathan
Childhood is critical for developing social, physical, and cognitive functioning. Burns in children are very different from burns in adults because it is difficult for them to save themselves. Their skin is more sensitive and less heat-resistant; their exposure may last longer, worsening the burn. When neglected, severe disabling and deforming contractures caused by burns in children can result in substantial impairment. Therefore, burn rehabilitation should not be carried out by one person but rather by a multidisciplinary team to ensure that all of the patients' physical, psychological, and social requirements are met while the child is in the hospital and after discharge...
August 2023: Curēus
https://read.qxmd.com/read/37686358/features-of-congenital-arthrogryposis-due-to-abnormalities-in-collagen-homeostasis-a-scoping-review
#27
REVIEW
Sarah MacKenzie Picker, George Parker, Paul Gissen
Congenital arthrogryposis (CA) refers to the presence of multiple contractures at birth. It is a feature of several inherited syndromes, notable amongst them are disorders of collagen formation. This review aims to characterize disorders that directly or indirectly impact collagen structure and function leading to CA in search for common phenotypic or pathophysiological features, possible genotype-phenotype correlation, and potential novel treatment approaches based on a better understanding of the underlying pathomechanism...
August 31, 2023: International Journal of Molecular Sciences
https://read.qxmd.com/read/37643934/diabetes-mellitus-related-musculoskeletal-disorders-unveiling-the-cluster-of-diseases
#28
REVIEW
Viktória Csonka, Cecília Varjú, Marcell Lendvay
The current study ushers in a comprehensive review in clinical research to demonstrate the prevalence of musculoskeletal (MSK) complications in diabetes mellitus and the most relevant clinical aspects. In particular, revealing the early symptoms of the disorders, the pathology lurking behind the complications and their optimal management. In diabetes mellitus, MSK complications are common and are largely due to similar pathogenetic factors responsible for the internal organ complications associated with diabetes leading to chronic low-intensity inflammatory processes...
August 27, 2023: Primary Care Diabetes
https://read.qxmd.com/read/37638523/physical-medicine-applications-in-hand-burns-treatment-or-rehabilitation
#29
JOURNAL ARTICLE
Hasan Murat Ergani, Elif Yalçın Topçuoğlu, Burak Yaşar, Ali Emre Akgün, Okan Acicbe, Merve Akın, Ramazan Erkin Ünlü, Ahmet Çınar Yastı
The aim of this study is to investigate the contribution of concurrent physical therapy to the preservation of hand function in patients with hand burns. This retrospective cohort study included the records of adult patients who presented with hand burns between July 1, 2020, and December 1, 2021. A total of 67 out of 1578 burn patients who attended the clinic were included in this study. The patients' age, sex, total body surface area with burns, causative agent, depth of burn on the hand, right or left hand, location of the burned area on the hand, treatment applied, healing time of the burn on the hand, limitation of movement, , the joint restrictions, contractures and compliance with physical therapy were assessed and recorded...
August 28, 2023: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://read.qxmd.com/read/37627841/the-developmental-implications-of-muscle-targeted-magnetic-mitohormesis-a-human-health-and-longevity-perspective
#30
REVIEW
Alfredo Franco-Obregón, Yee Kit Tai, Kwan Yu Wu, Jan Nikolas Iversen, Craig Jun Kit Wong
Muscle function reflects muscular mitochondrial status, which, in turn, is an adaptive response to physical activity, representing improvements in energy production for de novo biosynthesis or metabolic efficiency. Differences in muscle performance are manifestations of the expression of distinct contractile-protein isoforms and of mitochondrial-energy substrate utilization. Powerful contractures require immediate energy production from carbohydrates outside the mitochondria that exhaust rapidly. Sustained muscle contractions require aerobic energy production from fatty acids by the mitochondria that is slower and produces less force...
August 12, 2023: Bioengineering
https://read.qxmd.com/read/37477593/the-circular-paradox-of-including-people-with-severe-brain-injuries-and-reduced-decisional-capacity-in-research-a-feasibility-study-exploring-randomized-research-consent-based-recruitment-biases-and-the-resultant-health-inequities
#31
JOURNAL ARTICLE
Teresa Clark, Agnieszka Lewko, Melania Calestani
BACKGROUND: People with severe brain injuries (PSBI) and reduced capacity to consent (CTC) frequently develop muscle contractures. Standard care includes prolonged stretch (PS) but there is limited condition-specific evidence from randomized controlled trials (RCTs). PURPOSE: Identify factors affecting the inclusion of PSBI and reduced CTC in a PS RCT and methodologies more capable of generating condition-specific outcomes. METHODS: Mixed-method feasibility studies, including a pilot RCT (PSBI, adults with reduced CTC) comparing PS treatments (serial casting and splinting) and focus groups/interviews with physiotherapists involved in PS treatment...
July 21, 2023: Physiotherapy Theory and Practice
https://read.qxmd.com/read/37476105/guillain-barr%C3%A3-syndrome-presenting-as-painful-weakness-and-edema-of-the-legs-a-case-report
#32
Amteshwar Singh, Evani Jain, Venus Sharma, Amitasha Sinha, Waseem Khaliq
Guillain-Barré syndrome (GBS) is an autoimmune inflammatory polyneuropathy, which can be challenging to diagnose due to variability in the initial presenting features. Pain, flaccid paresis, motor sensory disturbance, hyporeflexia, and autonomic dysfunction are the typical manifestations, although atypical features, such as ataxia, neck stiffness, dysphagia, ophthalmoplegia, bulbar palsy, and isolated upper limb weakness, may be seen. It may also progress to fatal respiratory depression. As such, timely diagnosis and treatment are essential...
June 2023: Curēus
https://read.qxmd.com/read/37393478/the-activity-levels-and-quality-of-life-of-physically-disabled-children-who-continued-or-did-not-continue-rehabilitation-during-the-covid-19-pandemic
#33
JOURNAL ARTICLE
Fulya Senem Karaahmetoğlu, Esra Pehlivan, Zeynep Betül Özcan
BACKGROUND: Social isolation during the COVID-19 pandemic had a harmful impact on the psychological and physical health of children and teenagers. It is known that interruptions in rehabilitation can cause soft tissue contractures, bone deformities and a decline in motor functions among other complications. OBJECTIVE: The aim of this study was to compare the quality of life and physical activity levels of physically disabled children who continued and did not continue rehabilitation during the COVID-19 pandemic...
June 24, 2023: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://read.qxmd.com/read/37382676/the-benefits-of-physical-therapy-in-juvenile-idiopathic-arthritis
#34
REVIEW
Armando Di Ludovico, Saverio La Bella, Giulia Di Donato, Jon Felt, Francesco Chiarelli, Luciana Breda
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children and an important cause of short-term and long-term disability. Recommended physiotherapy activity programs are essential for controlling JIA associated complications such as stiffness, deformity, muscle contractures, and cramps. It is uncertain if physiotherapy (PT) can significantly enhance prognosis and quality of life (QOL). In this review we focused on the specific effects of various PT on JIA manifestations. To conduct a literature review, the databases PubMed, Scopus, and DOAJ (last access in June 2023) were searched...
June 29, 2023: Rheumatology International
https://read.qxmd.com/read/37238316/rehabilitation-in-patients-diagnosed-with-arthrogryposis-multiplex-congenita-a-systematic-review
#35
REVIEW
Catalina E García Aguilar, Cristina García-Muñoz, Ines Carmona-Barrientos, Maria Jesus Vinolo-Gil, Francisco Javier Martin-Vega, Gloria Gonzalez-Medina
Arthrogryposis multiplex congenita is a condition characterised by contractures and deformity in two or more body areas. Physiotherapy may be an appropriate treatment. The aim was to systematically review the evidence for rehabilitation in arthrogryposis multiplex congenita. A systematic review was performed following the PRISMA 2020 criteria. The search was conducted in PubMed, ScienceDirect, Scielo, Scopus, Web of Science, ENFISPO, JSTOR, Google Scholar, ProQuest, Cochrane Library and PEDro from inception until October 2022...
April 24, 2023: Children
https://read.qxmd.com/read/37237316/the-feasibility-of-negative-pressure-wound-therapy-versus-standard-dressings-in-paediatric-hand-and-foot-burns-protocol-a-pilot-single-centre-randomised-control-trial
#36
JOURNAL ARTICLE
Emma Lumsden, Roy Kimble, Catherine McMillan, Kristen Storey, Robert S Ware, Bronwyn Griffin
INTRODUCTION: The goal of paediatric hand and foot burn management is hypertrophic scar and/or contracture prevention. The risk of scar formation may be minimised by integrating negative pressure wound therapy (NPWT) as an acute care adjunct as it decreases the time to re-epithelialisation. NPWT has known associated therapeutic burden; however, this burden is hypothesised to be outweighed by an increased likelihood of hypertrophic scar prevention. This study will assess the feasibility, acceptability and safety of NPWT in paediatric hand and foot burns with secondary outcomes of time to re-epithelialisation, pain, itch, cost and scar formation...
May 26, 2023: Pilot and Feasibility Studies
https://read.qxmd.com/read/37201002/the-impact-of-the-covid-19-pandemic-on-children-with-disabilities-and-their-parents-or-caregivers
#37
JOURNAL ARTICLE
Nalan Capan, Özden Özyemişçi Taşkıran, Evrim Karadağ Saygı, Ebru Yılmaz Yalçınkaya, Berrin Hüner, Resa Aydın
OBJECTIVES: The study aimed to determine the impact of the pandemic on parents/caregivers and children with neurologic disabilities. PATIENTS AND METHODS: This multi-center cross-sectional study was conducted with 309 parents/caregivers (57 males, 252 females) and their 309 children (198 males, 111 females) with disabilities between July 5, 2020, and August 30, 2020. The parents/caregivers were able to answer the questions and had internet access. The survey included questions on the utilization of educational and health care services (whether they could obtain medicine, orthosis, botulinum toxin injection, or rehabilitation) during the pandemic...
March 2023: Turkish journal of physical medicine and rehabilitation
https://read.qxmd.com/read/37199482/reconstruction-of-finger-contracture-with-an-expanded-first-dorsal-metacarpal-artery-perforator-flap-a-case-report
#38
Burak Özkan, Burak Ergün Tatar, Süleyman Savran, Abbas Albayati, Cagri Ahmet Uysal
Volar finger contractures can be challenging for plastic surgeons. The dorsal metacarpal artery perforator (DMCAP) flap is frequently used to cover bones, tendons, and neurovascular structures in the dorsum of the hand after trauma and burns as an alternative to grafts and free flaps. We aimed to report volar finger defect reconstruction with expanded DMCAP flap. A 9-year-old male patient applied to our clinic with the complaint of inability to open the second finger of the left hand after an electrical burn that caused proximal and distal interphalangeal joints flexion contractures...
May 18, 2023: Microsurgery
https://read.qxmd.com/read/37197390/musculoskeletal-pain-management-and-thermotherapy-an-exploratory-analysis-of-italian-physicians-attitude-beliefs-and-prescribing-habits
#39
JOURNAL ARTICLE
Giuseppe Ventriglia, Fabrizio Gervasoni, Massimiliano Franco, Alberto Magni, Giorgio Panico, Giovanni Iolascon
PURPOSE: In Italy, musculoskeletal (MSK) disorders are pervasive with one-third of adults seeking medical consultation for a MSK issue in the past year. MSK pain is often treated with local heat applications (LHAs) which can be integrated into MSK care by different specialists and in different settings. Compared to analgesia and physical exercise, LHAs have been less evaluated, and the quality of randomized clinical trials is generally low. The aim of the survey is to assess the knowledge, attitude, perception/practices of general practitioners (GPs), physiatrists and sports medicine doctors towards thermotherapy as delivered by superficial heat pads or wraps...
2023: Journal of Pain Research
https://read.qxmd.com/read/37149384/critical-care-rehabilitation-of-the-burn-patient
#40
REVIEW
Jill M Cancio, William S Dewey
Despite the fact that modern burn care has significantly reduced the mortality associated with severe burn injuries, the rehabilitation and community reintegration of survivors continues to be a challenge. An interprofessional team approach is essential for optimal outcomes. This includes early occupational and physical therapy, beginning in the intensive care unit (ICU). Burn-specific techniques (edema management, wound healing, and contracture prevention) are successfully integrated into the burn ICU. Research demonstrates that early intensive rehabilitation of critically ill burn patients is safe and effective...
June 2023: Surgical Clinics of North America
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