Raza M Ahmad, Kyle Ingram, Ralph Corsetti
Background: Feminizing adrenal tumors are rare and generally malignant tumors usually seen in male adults and children. We report the case of a benign feminizing adrenal tumor in a male patient. To our knowledge, only 2 other cases of benign, estrogen-only-secreting adrenal tumors have been reported. Case Report: A 44-year-old male with a history of hypertension presented to his primary care physician with chest tenderness, fatigue, and erectile dysfunction. Hormonal workup and imaging identified an estrogen-only-secreting adrenal adenoma...
2020: Ochsner Journal
Essam M Akl, Ahmed A Salah
Hepatitis C virus (HCV) infection is a major health problem all over the world including Egypt. Chronic HCV infection is usually accompanied by decrease of libido and erectile dysfunction. This study aimed to evaluate the efficacy of new oral direct acting antiviral (DAA) therapy on sexual function of male patients with HCV. This study was conducted on 200 male participants divided into two groups, first group included 100 male patients with HCV and the second group included 100 healthy age matched males as a control...
October 18, 2020: Andrologia
Eric Allaire, Hélène Sussman, Ahmed S Zugail, Pascal Hauet, Jean Floresco, Ronald Virag
OBJECTIVE: Thirty per cent of cases of erectile dysfunction (ED)/male impotence are resistant to oral treatment. Half of these cases are due to blood drainage from the corpora cavernosa occurring too soon, due to cavernovenous leakage (CVL). The aim of this study was to report on an innovative treatment scheme combining pre- and post-operative haemodynamic assessment, venous embolisation, and open surgery for drug resistant ED caused by CVL. METHODS: An analysis of prospectively collected data, with clinical and haemodynamic pre- and post-operative assessment, was carried out...
October 13, 2020: European Journal of Vascular and Endovascular Surgery
Shu-Ying Li, Ya-Ling Zhao, Yu-Fan Yang, Xi Wang, Min Nie, Xue-Yan Wu, Jiang-Feng Mao
Background: Testosterone replacement therapy (TRT) is commonly used for the treatment of hypogonadism in men, which is often associated with type 2 diabetes mellitus (T2DM) and metabolic syndrome (Mets). Recent compiling evidence shows that TRT has beneficial metabolic effects on these patients. Objective: A meta-analysis has been conducted to evaluate the effects of TRT on cardiovascular metabolic factors. Methods: We conducted a systemic search on PubMed, Embase, Cochrane Library, Wanfang, and CNKI and selected randomized controlled trials (RCTs) to include...
2020: International Journal of Endocrinology
Katelynn M Wilton, Sara J Achenbach, Paras Karmacharya, Floranne C Ernste, Eric L Matteson, Cynthia S Crowson
OBJECTIVE: To define the incidence of erectile dysfunction (ED) in a population-based cohort of men with psoriatic arthritis (PsA). METHODS: Data pertaining to demographics, ED, and potential confounding diagnosis were extracted from a comprehensive medical record system for a population-based cohort of men with PsA and an age-matched male comparator cohort. Cumulative incidence of ED adjusted for competing risk of death was compared between the two cohorts. RESULTS: There were 128 age-matched pairs of men with PsA and without PsA in the described cohorts...
October 15, 2020: Journal of Rheumatology
Iyimser Ure, Ata Ozen
AIM: There are few types of drugs that can be used in the active phase of Peyronie's disease. Methylprednisolone is a corticosteroid with a strong anti-inflammatory effect. In this study, we aimed to evaluate the effect of intralesional low dose methylprednisolone treatment on patients in the active phase of Peyronie's disease. PATIENTS AND METHODS: Forty-eight patients suffering from Peyronie's disease active phase symptoms were included in the study. Methylprednisolone was administered intralesionally for 8 weeks, once per week, at a dose of 40 mg...
October 15, 2020: International Journal of Clinical Practice
D Hernández Rodríguez, S Pérez-de la Cruz
Pelvic floor disorders are one of the most common complications in male patients with spinal cord injury. The aim of this review was to analyse the available evidence on the efficacy of different treatments used for pelvic floor dysfunctions in men with incomplete spinal cord injuries. The Scopus, Medline, PEDro, Web of Science, Dialnet, Pubmed and Cochrane databases were consulted for papers in Spanish and English published in the last twenty years. Fifteen articles were included, comprising a total of 706 male patients with incomplete spinal cord injury...
October 15, 2020: Anales del Sistema Sanitario de Navarra
Ruocong Yang, Chao Liu, Qianqian Li, Weilu Wang, Bingbing Wu, Aiping Chen, Bin Wang, Wei Li, Jianxin Chen
Diabetic erectile dysfunction (DED) hugely affected the patients' sexual life quality. However, there are no satisfactory therapeutic methods and intervention targets for this subtype of erectile dysfunction (ED). Inspired by the clinical practice of traditional Chinese medicine (TCM), we found that hirudin, the main active ingredient in the leech, could ameliorate the ED symptoms of the DED mouse model. To further reveal the underlying mechanism of hirudin, we designed a novel strategy to discover potential targets based on the diagnostic system of TCM, and found that myeloperoxidase (MPO) was a the promising target of hirudin...
October 11, 2020: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
Dongyi Peng, Yan Tan, Amanda B Reed-Maldonado, Guiting Lin, Tom F Lue
Sufficient functional repair of damaged peripheral nerves is a big clinical challenge in terms of long-lasting morbidity, disability, and economic costs. Nerve damage after radical prostatectomy is the most common cause of erectile dysfunction (ED). In recent years, low-intensity extracorporeal shockwave therapy (Li-ESWT) has been explored to improve the outcomes of peripheral nerve repair and regeneration. Research indicated that application of Li-ESWT after nerve surgery promoted nerve regeneration and improved the functional outcomes, underlined the mechanisms related to increase of neurotrophic factors, Schwann cells activation, and cellular signaling activation for cell activation and mitosis induced by Li-ESWT...
October 9, 2020: Turkish Journal of Urology
Priyank Yadav, Nayab Danish, Sanjoy S Sureka, Sanchit Rustagi, Rakesh Kapoor, Aneesh Srivastava, Uday Pratap Singh
OBJECTIVE: In complex strictures, especially in elderly patients, perineal urethrostomy (PU) provide excellent voiding function. This study aimed at evaluating the long-term voiding and erectile function of PU as a permanent procedure for such strictures. MATERIAL AND METHODS: We retrospectively evaluated 146 patients who underwent permanent PU at our institution from January 2000 to December 2018. All patients had complex urethral strictures. Patients with posterior urethral involvement were excluded...
October 9, 2020: Turkish Journal of Urology
Gaurav Sharma, Soumendranath Mandal, Prasenjit Bhowmik, Prashant Gupta, Bandhan Bahal, Pramod Kumar Sharma
OBJECTIVE: To determine the erectile dysfunction (ED), overall sexual function, and risk factors for developing ED after surgical repair of penile fracture. MATERIAL AND METHODS: This was an ambispective observational study conducted from September 2014 to August 2019, which included 68 patients with a clinical diagnosis of penile fracture. The clinical presentation, etiology, and surgical details were recorded. Patients were contacted via telephone and called for follow-up...
October 9, 2020: Turkish Journal of Urology
Peng Cheng, Yiling Shi, Lizhi Xu, Ying Zhou, Weihui Li
Somatic symptom disorder (SSD) is a somatic disorder characterized by excessive anxiety over various somatic symptoms for a long time, which makes patients feel very painful and the quality of personal life significantly decreased. Previous studies have shown that there is a connection between the clinical manifestations of SSD patients and their cultural background. The patient in this case report was highly affected by Chinese yin-yang culture, displaying obvious Chinese characteristics.We report a patient with SSD, whose clinical manifestations were mainly sexual dysfunction and mood symptoms which were closely related to the Traditional Chinese culture of Yin and Yang...
2020: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
Jisu Kim, Insil Jang
The aim was to adapt and validate the Modified Transplant Symptom Occurrence and Symptom Distress Scale (MTSOSD-59R) for kidney transplant recipients undergoing immunosuppressive therapy in Korea. The MTSOSD-59R has been used with solid organ transplant recipients globally to assess the adverse effects of immunosuppressive medication. A descriptive cross-sectional design was used. MTSOSD-59R was first translated, and pilot tested. Next, content validity was established with nine organ transplant experts. Then, from October 2017 to October 2018, the Korean MTOSOSD-59R was administered to a convenience sample of 122 kidney transplant recipients recruited from a single center...
October 8, 2020: International Journal of Environmental Research and Public Health
Ji-Sheng Wang, Xiao Li, Zi-Long Chen, Jun-Long Feng, Bing-Hao Bao, Sheng Deng, Heng-Heng Dai, Fan-Chao Meng, Bin Wang, Hai-Song Li
ETHNOPHARMACOLOGICAL RELEVANCE: Leeches (pinyin name Shui Zhi; Latin scientific name Hirudo;Hirudinea;Hirudinidae) and centipedes (pinyin name Wu Gong;Latin scientific name Scolopendridae;Chilopoda;Scolopendridae) are traditional Chinese medicines, and they belong to the family entomology. A combination of leech and centipede is used as an effective medicine to promote blood circulation and remove blood stasis in traditional Chinese medicine, and "leech-centipede" medicine has been used in many prescriptions to treat diabetic vascular disease, including diabetic erectile dysfunction(DIED)...
October 10, 2020: Journal of Ethnopharmacology
Chirag N Dave, Taylor P Kohn, Hiten D Patel, Ali Arafa, Arthur L Burnett
INTRODUCTION Few studies have compared surgical outcomes after 3-piece inflatable penile prosthesis (IPP) surgery in patients exposed to pelvic radiation therapy (RT) compared to a radiation naïve control group. MATERIALS AND METHODS: A total of 715 consecutive patients underwent 3-piece IPP placement between 2007-2018. There were 101 men exposed to pelvic RT before or after IPP for a variety of malignancies and 153 men met inclusion criteria for the control group, which included men undergoing IPP surgery with a history of radical prostatectomy but no exposure to pelvic RT...
October 2020: Canadian Journal of Urology
Anna Mortzfeldt
This article reviews the prostatic urethral lift (PUL) and its potential benefits and risks compared with transurethral resection of the prostate (TURP). TURP is the traditional procedure for benign prostatic hyperplasia (BPH), and is associated with ejaculatory and erectile dysfunction. PUL is a minimally invasive option, but its efficacy has not been well studied. A literature review indicates that both procedures should be afforded equal consideration, and both have limitations. Further long-term research is needed to establish if PUL is superior to TURP...
October 9, 2020: JAAPA: Official Journal of the American Academy of Physician Assistants
Hugo Otaola-Arca, Manuel Álvarez-Ardura, Roberto Molina-Escudero, Mario I Fernández, Álvaro Páez-Borda
OBJECTIVE: To generate high-quality data comparing the clinical efficacy and safety profile between monopolar transurethral resection of the prostate (M-TURP) and bipolar plasmakinetic resection of the prostate (PK-TURP) for benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Prospective, randomized, single-blinded study conducted in a tertiary-care public institution (Dec/2014-Aug/2016). INCLUSION CRITERIA: prostate of <80g in patients with drug-refractory lower urinary tract symptoms (LUTS), complications derived from BPH, or both...
January 2021: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Louise A Corben, Mireille M Hermans, Alice Marks, Louise M Crowe, Martin B Delatycki
BACKGROUND: Sexual dysfunction (SD) is reported in neurological conditions similar to Friedreich ataxia (FRDA). Anecdotally individuals with FRDA report SD including erectile dysfunction and altered genital sensation. Understanding SD in FRDA assists health professionals identify SD issues and improve healthcare for individuals with FRDA. OBJECTIVE: To quantify if, and to what extent, people with FRDA experience challenges with sexual function and intimate relationships as a result of primary (genital function), secondary (physical) and tertiary (psychosocial) dysfunction...
October 12, 2020: Journal of Neurology
Arthur L Burnett, Natalie C Edwards, Tonya M Barrett, Krista D Nitschelm, Samir K Bhattacharyya
Erectile dysfunction (ED) is a common, burdensome, and costly urologic condition strongly related to all aspects of general health, from physical to mental. ED has profound consequences as it may interfere physical well-being, quality of life (QoL), self-esteem, relationships, self-worth, and productivity. It is therefore important to ensure that all types of effective ED treatments are consistently accessible to patients. While federal and state mandates ensure access to treatment for women's breast health, female-factor infertility, and gender affirmation to ensure that these individuals do not experience a diminished QoL, there are no comparable mandates for men's sexual and reproductive health...
September 2020: American Journal of Men's Health
Michael Pinkawa, Amr Gharib, Marsha Schlenter, Ludmila Timm, Michael J Eble
PURPOSE: Analysis of quality of life changes after radiotherapy with focus on the impact of time after treatment and prescription dose. METHODS: Consecutive patients were treated with doses from 70.2/1.8 Gy (n = 206) to 72/1.8-2.0 Gy (n = 176) in a single centre and surveyed using the Expanded Prostate Cancer Index Composite questionnaire. RESULTS: Urinary and bowel bother scores decreased 1 / 3 / 6 points and 7 / 7 / 9 points on average 1 / 5 / 10 years after RT in comparison to baseline scores...
October 9, 2020: Quality of Life Research
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