Pedro-Santiago Borrego-Jimenez, Bárbara-Yolanda Padilla-Fernandez, Sebastián Valverde-Martinez, Maria-Helena Garcia-Sanchez, Maria-de-la-O Rodriguez-Martin, Maria-Pilar Sanchez-Conde, Maria-Carmen Flores-Fraile, Magaly Marquez-Sanchez, Javier Flores-Fraile, Miguel Perán-Teruel, José-Antonio Mirón-Canelo, Maria-Begoña García-Cenador, María-Fernanda Lorenzo-Gómez
OBJECTIVES: to demonstrate the benefits of physiotherapy (PT) with pelvic floor biofeedback (BFB) in improving health-related quality of life when used as a complementary therapy after surgical treatment of cystocele, in cases in which perineal pain or discomfort persists. MATERIALS AND METHODS: prospective observational study in 226 women who received complementary therapy after surgical treatment of cystocele due to persistent perineal discomfort or pain. Groups: GA ( n = 78): women treated with 25 mg of oral pregabalin every 12 h plus BFB, consisting of 20 once-weekly therapy sessions, each 20 min long, with perineal pregelled surface electrodes connected to a screen which provides visual feedback; GB ( n = 148): women treated with oral pregabalin 25 mg every 12 h without BFB...
October 15, 2020: Journal of Clinical Medicine
A M Ochiai, N M Araújo, S D T A Moraes, A Caroci-Becker, L G Sparvoli, T T Teixeira, R R Carvalho
BACKGROUND AND PROBLEM: Surgical glue has been indicated for uncomplicated operatory wounds; however, it has a considerable cost. Non-surgical glue, a commercially available and cheaper product, has not been studied for repairing postpartum lacerations. AIM: To compare non-surgical glue to traditional sutures on perineal first-degree lacerations after normal birth. METHODS: In a prospective, open-label, non-inferiority, randomised controlled trial, we selected childbearing women who were admitted for normal term births and in whom skin lacerations occurred...
October 15, 2020: Women and Birth
Zdenek Rusavy, Vladimir Kalis, Salavat Aglyamov, Vladimir Egorov
INTRODUCTION AND HYPOTHESIS: Quantitative characterization of the birth canal and critical structures before delivery may provide risk assessment for maternal birth injury. The objective of this study was to explore imaging capability of an antepartum tactile imaging (ATI) probe. METHODS: Twenty randomly selected women older than 21 years with completed 35th week of pregnancy and a premise of vaginal delivery were enrolled in the feasibility study. The biomechanical data were acquired using the ATI probe with a double-curved surface, shaped according to the fetal skull and equipped with 168 tactile sensors and an electromagnetic motion tracking sensor...
October 17, 2020: International Urogynecology Journal
Katleen Jottard, Luc Bruyninx, Pierre Bonnet, Nathalie Mathieu, Stefan De Wachter
INTRODUCTION AND HYPOTHESIS: Chronic perineal pain syndrome due to pudendal nerve impingement is difficult to diagnose and to treat. All the known treatment options leave room for improvement considering the outcome. Early neuromodulation of the pudendal nerve after its surgical release could improve outcomes. OBJECTIVES: The aim of the study was to evaluate the potential beneficial effect of pudendal neuromodulation combined with release surgery using the ENTRAMI technique (endoscopic transgluteal minimally invasive technique)...
October 13, 2020: International Urogynecology Journal
Christine E East, Emma Df Dorward, Rhiannon E Whale, Jiajia Liu
BACKGROUND: Perineal trauma is common during childbirth and may be painful. Contemporary maternity practice includes offering women numerous forms of pain relief, including the local application of cooling treatments. This Cochrane Review is an update of a review last updated in 2012. OBJECTIVES: To evaluate the effectiveness of localised cooling treatments compared with no treatment, placebo, or other cooling treatments applied to the perineum for pain relief following perineal trauma sustained during childbirth...
October 9, 2020: Cochrane Database of Systematic Reviews
Jing Chen, Haomin Zhang, Di Niu, Hu Li, Kun Wei, Li Zhang, Shuiping Yin, Longfei Liu, Xiansheng Zhang, Meng Zhang, Chaozhao Liang
BACKGROUND: Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a disease with diverse clinical manifestations, such as pelvic pain or perineal pain. Although recent studies found several risk factors related to the pain severity of CP/CPPS patients, results were inconsistent. Here, we aimed to identify novel risk factors that are closely related to the severity of pain in patients with CP/CPPS. METHODS: We retrospectively collected the clinical records from patients with CP/CPPS from March 2019 to October 2019...
October 7, 2020: BMC Urology
Athina Giovanis, Stephanie Zeszutek
Vulvodynia is chronic perineal pain in women. Repercussions of this disorder can have a negative effect on women's health and lifestyle. The origin is often multifactorial, including pelvic and lower extremity somatic dysfunctions. If left untreated, these somatic dysfunctions can directly alter ligamentous tension on the pelvic floor and surrounding regions, resulting in perineal pain. Management of vulvodynia must be individualized due to the multifactorial etiology and complicated structure and function of the pelvic floor muscles...
November 1, 2020: Journal of the American Osteopathic Association
J D Lu, M Milakovic, V Piguet, A Alavi
Hidradenitis suppurativa (HS) is a chronic inflammatory condition which affects apocrine gland-rich skin.1 It primarily develops in intertriginous areas, including the axilla, groin, perianal, and perineal regions and presents with recurrent, painful nodules, abscesses, draining tunnels, and scarring.1 Despite the continuing research and development of biologics for HS, biologics can lead to the formation of anti-drug antibodies (ADAs) that inactivate the therapeutic effects of the treatment, leading to a decreased drug level and resulting in a suboptimal response...
October 2, 2020: British Journal of Dermatology
Michele Bartoletti, Roberta Mazzeo, Marco De Scordilli, Anna Del Fabro, Maria Grazia Vitale, Lucia Bortot, Milena Sabrina Nicoloso, Serena Corsetti, Marta Bonotto, Simona Scalone, Giorgio Giorda, Roberto Sorio, Claudia Andreetta, Maria Luisa Meacci, Rocco De Vivo, Gianpiero Fasola, Francesco Sopracordevole, Fabio Puglisi
BACKGROUND: Invasive vulvar Paget's disease with over-expression of the human epidermal growth factor receptor 2 (HER2) protein is potentially suitable for targeted therapy, especially in a metastatic setting where no effective treatments are available. METHODS: Four consecutive patients with HER2 positive advanced vulvar Paget's disease, treated with weekly trastuzumab (loading dose 4 mg/kg, then 2 mg/kg) and paclitaxel (80 mg/m2 ) followed by 3-weekly trastuzumab maintenance (6 mg/kg), are reported...
September 30, 2020: International Journal of Gynecological Cancer
Theodora Billi, Vasiliki Karadima, Panagiota Tyrnenopoulou, Emmanouela P Apostolopoulou, Georgia D Brellou, Nikolaos Diakakis
BACKGROUND: A 20-year-old grey Warmblood gelding that had history of dermal melanomatosis. OBJECTIVE: To report surgical treatment of a 6-cm large malignant metastatic melanoma located in the cutaneous trunci muscle of the left lateral thorax of a horse. METHODS: A 20-year-old grey Warmblood gelding was referred for evaluation of a large, rapidly growing, thoracic mass. Clinical examination revealed an ovoid, firm, non-painful, movable mass, approximately 6 cm in diameter, located in the cutaneous trunci muscle of the left lateral thorax...
September 29, 2020: Veterinary Medicine and Science
Ioannis Mykoniatis, Dimitrios Kalyvianakis, Filimon Zilotis, Paraskevi Kapoteli, Agrippina Fournaraki, Evangelos Poulios, Dimitrios Hatzichristou
BACKGROUND: Currently, there is no efficacious treatment method for chronic prostatitis type IIIb/chronic pelvic pain syndrome (CP/CPPS). Aim of the study was to investigate and compare the efficacy and safety of low-intensity shockwave therapy (LiST) vs. sham treatment in CP/CPPS patients. METHODS: Patients with CP/CPPS diagnosis were randomized in this prospective, sham-controlled, double-blind study either to the active groups (Group B, C) who received 5000 shockwaves per session with energy flux density 0...
September 28, 2020: Prostate Cancer and Prostatic Diseases
Kate M Levett, Sarah J Lord, Hannah G Dahlen, Caroline A Smith, Federico Girosi, Soo Downe, Kenneth William Finlayson, Julie Fleet, Mary Steen, Mary-Ann Davey, Elizabeth Newnham, Anette Werner, Leslie Arnott, Kerry Sutcliffe, Anna Lene Seidler, Kylie Elizabeth Hunter, Lisa Askie
INTRODUCTION: Rates of medical interventions in normal labour and birth are increasing. This prospective meta-analysis (PMA) proposes to assess whether the addition of a comprehensive multicomponent birth preparation programme reduces caesarean section (CS) in nulliparous women compared with standard hospital care. Additionally, do participant characteristics, intervention components or hospital characteristics modify the effectiveness of the programme? METHODS AND ANALYSIS: Population : women with singleton vertex pregnancies, no planned caesarean section (CS) or epidural...
September 23, 2020: BMJ Open
Percela Moscoso Tence Marks, Adriana Caroci-Becker, Wesllanny Sousa Brunelli, Sheyla Guimarães de Oliveira, Marlise de Oliveira Pimentel Lima, Maria Luiza Gonzalez Riesco
OBJECTIVE: To compare the intensity of pain, the healing process and women's satisfaction with the repair of perineal trauma during vaginal delivery using surgical glue or suture. METHOD: Cross-sectional study aligned with a clinical trial conducted at a maternity in Itapecerica da Serra, São Paulo. The sample consisted of women who were evaluated between 10 and 20 days after delivery. The outcomes were analyzed according to the distribution of women in the experimental group (EG: perineal repair with Glubran-2® surgical glue; n=55) and in the control group (CG: perineal repair with Vicryl® suture thread; n=55)...
2020: Revista da Escola de Enfermagem da U S P
Taithongchai, I Pandeva, A H Sultan, R Thakar
OBJECTIVES: To present the characteristics of women attending a tertiary urogynaecology pelvic floor scan clinic with mid-urethral sling complications and examine the association between 2D perineal and 3D endovaginal ultrasound and symptoms. METHODS: A cross-sectional study of all women referred to a specialist pelvic floor ultrasound clinic from October 2016 to October 2018 with mid-urethral sling complications were included. They underwent a detailed history and had a 2D perineal (BK Medical, Herlev, Denmark, Type 8802; 4...
September 22, 2020: Ultrasound in Obstetrics & Gynecology
N A Okeahialam, R Thakar, H Kleprlikova, A Taithongchai, A H Sultan
OBJECTIVES: To describe post-operative outcomes following early re-suturing of obstetric perineal wound dehiscence. STUDY DESIGN: This was a retrospective series of 72 women who underwent re- suturing of a dehisced perineal wound at a tertiary urogynaecology department during a 13-year period (December 2006 - December 2019). RESULTS: Seventy-two women with complete perineal wound dehiscence opted for secondary re-suturing. Other accompanying symptoms included purulent discharge from the wound (22...
September 10, 2020: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Jenna B Wowdzia, Tara-Leigh McHugh, Jane Thornton, Allison Sivak, Michelle F Mottola, Margie H Davenport
PURPOSE: The purpose of this systematic review was to evaluate fetal and maternal pregnancy outcomes of elite athletes who had participated in competitive sport immediately prior to conception. METHODS: Online databases were searched up to March 24, 2020. Studies of any design and language were eligible if they contained information on the relevant population (pregnant women), exposure (engaged in elite sport immediately prior to pregnancy), and outcomes (birthweight, low birthweight, macrosomia, preterm birth, fetal heart rate and pulse index, cesarean sections, instrumental deliveries, episiotomies, duration of labor, perineal tears, pregnancy induced low back pain, pelvic girdle pain, urinary incontinence, miscarriages, prenatal weight gain, inadequate/excess prenatal weight gain, maternal depression or anxiety)...
September 11, 2020: Medicine and Science in Sports and Exercise
Moira Chia, Christopher Ho
An adolescent girl presented with hypertension and was found to have haematocolpos and imperforate hymen. She had a background of chronic abdominal pain and had sought medical attention multiple times prior, with the diagnosis being missed as pubertal evaluation and perineal examination had been neglected during those visits. Hypertension resolved following hymenectomy and drainage of haematocolpos with no long-term sequelae.
September 9, 2020: BMJ Case Reports
Ausra Cerniauskiene, Marija Barisiene, Arnas Bakavicius, Ramune Kavaliauskaite, Albertas Cekauskas, Arunas Zelvys
Introduction: Argus suburethral sling implantation is a minimally invasive operation with the possibility to adjust the tension of the sling at any time after the procedure, which provides good treatment results for male stress urinary incontinence (SUI). Aim: To determine the predictive factors, the incidence, severity and timing of the onset of complications after Argus sling implantation for males with post-operative SUI. Material and methods: A total of 41 patients who underwent Argus sling implantation due to post-operative SUI were included...
September 2020: Videosurgery and Other Miniinvasive Techniques
Rachael A Ward, Nneka S Udechukwu, Maria A Selim, Tarannum Jaleel
Poorly controlled and long-standing hidradenitis suppurativa (HS) increases the risk of squamous cell carcinoma (SCC). We report a 54-year-old woman with an over 20-year history of HS, who had previously undergone wide perineal excision with secondary intention healing and presented with a painful verrucous vulvar plaque and proximal non-healing perineal wound. The patient had four perineal scouting biopsies performed and excisional biopsy with no evidence of high-grade dysplasia or carcinoma on histology. Chromogenic in situ hybridization was negative for HPV 16 and 18 mRNA; the patient's HIV and HSV PCR were also negative...
June 15, 2020: Dermatology Online Journal
Antonio Macedo, Ricardo Del Debbio Di Migueli, Sérgio Leite Ottoni, Marcela Leal da Cruz, João Padua Manzano
INTRODUCTION: Prostatic utricle cysts result from incomplete regression of Mullerian duct structures and occur most frequently in males with perineal or peno-scrotal hypospadias. Utricular cysts may present with various signs and symptoms including urinary tract infection, pain and post-void incontinence, a palpable abdominal mass or recurrent epididymitis. MATERIAL AND METHODS: We present a 12 months boy we treated due to proximal hypospadias in two stages, in association to a dysplastic undescended testis that was excised...
August 26, 2020: Journal of Pediatric Urology
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