William T Schnettler, Caitlyn K Zinn, C Ganga Devaiah, John Wilson
OBJECTIVE: Few obstetric-specific guidelines detail the indications for screening echocardiography in pregnancy. The objective of the study is to examine the association of common indications for maternal echocardiography with the likelihood of abnormality identification, pregnancy management alteration, and conformity with current American College of Cardiology Foundation (ACCF) guidelines. STUDY DESIGN:  This retrospective cohort analysis categorized all echocardiograms performed within pregnancy and the first month postpartum within a tertiary health system to correlate indications with abnormal findings...
May 4, 2021: American Journal of Perinatology
Shishir Kumar, Parveen Kumar, Khushboo Jha, Arti Khatri
The presence of hepatic parenchyma at ectopic locations is infrequently reported in neonatal age. Case details: A male neonate presented with clinical signs and symptoms of duodenal obstruction. At exploration, an annular pancreas was found as the causative factor and he underwent a Kimura's duodeno-duodenostomy. A pedicled cyst was attached to the stomach's greater curvature, was excised, and histologically was a mesothelial-lined cyst with ectopic liver, complete with bile ducts, in the cyst wall. Conclusion: Ectopic liver tissue may be clinically silent and found within the wall of a mesothelial cyst...
May 4, 2021: Fetal and Pediatric Pathology
Jessica P Preslar, Mary Claire Worrell, Reinhard Kaiser, Carrie Jo Cain, Solomon Samura, Amara Jambai, Pratima L Raghunathan, Kevin Clarke, David Goodman, Lauren Christiansen-Lindquist, Amy Webb-Girard, Michael Kramer, Robert Breiman
INTRODUCTION: In low-resource settings, a social autopsy tool has been proposed to measure the effect of delays in access to healthcare on deaths, complementing verbal autopsy questionnaires routinely used to determine cause of death. This study estimates the contribution of various delays in maternal healthcare to subsequent neonatal mortality using a social autopsy case-control design. METHODS: This study was conducted at the Child Health and Mortality Prevention Surveillance (CHAMPS) Sierra Leone site (Makeni City and surrounding rural areas)...
May 4, 2021: Maternal and Child Health Journal
Antonella Di Caprio, Elena Coccolini, Paola Zagni, Eleonora Vaccina, Laura Lucaccioni, Licia Lugli, Lorenzo Iughetti, Alberto Berardi
BACKGROUND: Bronchiolitis is a common cause of hospitalisation of infants less than a year old, with most infants recovering without complications. Respiratory syncytial virus (RSV) is a leading cause of bronchiolitis. Antimicrobial stewardship programmes do not recommend antibiotics for viral infections in neonates unless documented evidence of secondary bacterial infection is present. CASE REPORT: We present the case of a 7-day-old infant admitted to hospital with chest retractions and fever...
April 30, 2021: Acta Bio-medica: Atenei Parmensis
Khaled Mohammed Al-Jamrah, Basheer Abdulgalil Al Nabehi, Khaled Abdullah Almoayed, Labiba Saeed Anam, Yousef S Khader
BACKGROUND: The Neonatal Tetanus Surveillance System (NTSS) in Yemen was established in 2009 to identify high-risk areas, determine trends, and evaluate elimination activities. Since its launch, the NTSS had never been evaluated. OBJECTIVE: This study aimed to assess the performance of NTSS and determine its strengths and weaknesses to recommend improvements. METHODS: The US Centers for Disease Control and Prevention (CDC) guidelines were used for evaluating the NTSS...
May 4, 2021: JMIR Public Health and Surveillance
Jennifer L Harenberg, Robert Church, Tito D Tubog
Physiologic changes during pregnancy may increase the risk of coronavirus disease 2019 (COVID-19) infection. Limited data show serious complications of COVID-19 infection and pregnancy. Severe adverse maternal and perinatal outcomes such as preterm delivery, intensive care unit admission, and neonatal and intrauterine death have been reported. Our knowledge of the epidemiology, pathogenesis, disease progression, and clinical course of COVID-19 is continually changing as more information and evidence emerge...
August 2020: AANA Journal
Perry Friedman, Ali Yilmaz, Zafer Ugur, Faryal Jafar, Amy Whitten, Ilyas Ustun, Onur Turkoglu, Stewart Graham, Ray Bahado Singh
OBJECTIVE: To identify maternal second and third trimester urine metabolomic biomarkers for the detection of fetal congenital heart defects (CHDs). STUDY DESIGN: This was a prospective study. Metabolomic analysis of randomly collected maternal urine was performed, comparing pregnancies with isolated, non-syndromic CHDs versus unaffected controls. Mass spectrometry (liquid chromatography and direct injection and tandem mass spectrometry, LC-MS-MS) as well as nuclear magnetic resonance spectrometry, 1 H NMR, were used to perform the analyses between 14 0/7 and 37 0/7 weeks gestation...
May 4, 2021: Journal of Maternal-fetal & Neonatal Medicine
Guoyu Sun, Baihua Jing, Faliang Zhou, Hongyan Liu, Lili Liu, Junya Chen, Xinlin Hou
OBJECTIVE: To determine the differences in outcomes between mild and moderate isolated ventriculomegaly (IVM). METHODS: We conducted a prospective cohort study on 94 fetuses with IVM and evaluated the neurodevelopmental outcomes at 12 months of age using the ASQ-3 and BSID-I neurodevelopmental assessment tools. Progression of VM was defined as an increase in the width of the ventricular by at least 3 mm during sequential ultrasound monitoring. The population was divided into two groups according to ventricular width: mild (10-12 mm) and moderate (12...
May 4, 2021: Journal of Maternal-fetal & Neonatal Medicine
Shiva Alizadeh, Hedyeh Riazi, Hamid Alavi-Majd, Giti Ozgoli
BACKGROUND: Sexual dysfunction is potential abnormality in the ability of a person to sexual respond or enjoy sexual experience. During pregnancy, sexual function is at risk and disorder due to physical, hormonal and psychological changes. The prevalence of female sexual dysfunction is very variable during pregnancy. OBJECTIVE: The aim of this study was to determine the prevalence of sexual dysfunction in pregnant women in the Eastern Mediterranean Regional Office Countries (EMRO) by meta-analysis and systematic methods...
May 4, 2021: Journal of Maternal-fetal & Neonatal Medicine
Mariana Simões, Gonçalo Vale, Catarina Lacerda, Patricia Pais, Diana Pignatelli
Fetomaternal hemorrhage (FMH) is a known cause of neonatal anemia due to fetal blood loss to the maternal circulation, occurring when the maternal-fetal barrier is disrupted. Several causes must be considered, although in most cases the etiology remains unknown. Intraplacental choriocarcinoma (ICC) is a rare entity and has been related with massive FMH, intrauterine fetal demise, severe neonatal anemia and metastatic choriocarcinoma in both mother and infant. There are 25 cases of histopathologically confirmed ICC complicated with FMH described in the literature...
May 4, 2021: Journal of Maternal-fetal & Neonatal Medicine
Sofia Benou, Gabriel Dimitriou, Vassiliki Papaevangelou, Despoina Gkentzi
BACKGROUND: Cytomegalovirus (CMV) is the most frequent cause of congenital infection worldwide causing serious morbidity in newborns, infants, and children. Despite the clinical importance of congenital CMV (cCMV), studies conducted so far conclude that there is limited awareness in both the medical community and public of cCMV infection. The aim of this systematic review was to assess the knowledge and awareness of cCMV among pregnant women and healthcare providers during the last decade...
May 4, 2021: Journal of Maternal-fetal & Neonatal Medicine
Jing Wang, Damin Zhu, Jiaqian Yin, Cong Ma, Xiaoqing Peng, Huijuan Zou, Yunxia Cao, Xiaofeng Xu
OBJECTIVE: To investigate the expression and sources of high mobility group box 1 (HMGB1) protein in the maternal-fetal interface of patients with unexplained recurrent spontaneous abortion (URSA), and further to verify the role of HMGB1 in the etiology of URSA. METHODS: 55 women at early pregnancy with URSA and 55 women undergoing selective termination of normal early pregnancy as control were included. The abortion tissues including villi and decidua were collected...
May 4, 2021: Journal of Maternal-fetal & Neonatal Medicine
Harsimran Kaur, Shreya Singh, Shivaprakash M Rudramurthy, Muralidharan Jayashree, Nitin James Peter, Pallab Ray, Ram Samujh, Anup Ghosh, Arunaloke Chakrabarti
BACKGROUND: Considering the emergence of fungaemia due to rare yeasts at our centre, we performed a systematic epidemiologic study on fungaemia due to rare yeast. OBJECTIVES: We undertook the present prospective observational study to explore the epidemiological features, clinical characteristics, of fungaemia due to rare yeasts in paediatric ICUs at our centre. METHODS: The successive yeasts isolated from blood at our PICUs during December 2017 through March 2019 were identified by molecular methods...
May 3, 2021: Mycoses
Salima Rattani, Joveria Farooqi, Ali Shabbir Hussain, Kauser Jabeen
BACKGROUND: Neonatal candidemia leads to high morbidity and mortality in developing countries. We studied the trends, spectrum and antifungal resistance in neonatal candidemia isolates from the year 2014 to 2019. METHODS: This was a cross-sectional study conducted at the Aga Khan University, Pakistan. Neonates with positive blood cultures with Candida species were retrospectively identified from the laboratory database (2014-2018) and prospectively in 2019 where clinical information was also collected as part of routine laboratory reporting...
May 3, 2021: Pediatric Infectious Disease Journal
Gwendoline Chimhini, Ioana Diana Olaru, Felicity Fitzgerald, Mutsawashe Chisenga, Cecilia Ferreyra, Nada Malou, Jeremie Piton, Simbarashe Chimhuya, Shunmay Yeung, Surjo De, Hilda A Mujuru, Katharina Kranzer
BACKGROUND: Neonatal sepsis accounts for a large proportion of neonatal deaths in sub-Saharan Africa. The lack of access to diagnostic testing and excessively long turnaround times to result contributes to delays in sepsis identification and initiation of appropriate treatment. This study aims to evaluate the novel InTrays COLOREX Screen and extended-spectrum beta-lactamase for rapid identification of bacterial pathogens causing sepsis and detection of resistance. METHODS: Neonates with suspected sepsis admitted to the Harare Central Hospital were prospectively enrolled...
May 3, 2021: Pediatric Infectious Disease Journal
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April 28, 2021: Nursing for Women's Health
(no author information available yet)
No abstract text is available yet for this article.
April 27, 2021: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
Johan A Jamaluddin, Norliza Ali
Supracardiac total anomalous pulmonary venous drainage is commonly associated with a left-sided ascending vein draining into innominate vein. We present a case of a newborn with a right-sided ascending vein, draining into the right superior caval vein with stenosis at the SVC-ascending vein junction, posing a surgical dilemma in corrective surgery. Usage of three-dimensional computed tomographic scan was essential in delineating the anatomy and aiding surgery. The case demonstrates the rarity of this type of cardiac disease and the complications that develop...
May 4, 2021: Cardiology in the Young
Atilla Cayir, Ali Akyigit, Ufuk Utku Gullu, Hasan Kahveci, Duran Yildiz, Erdal Kurnaz, Dogus Vuralli, Abdulkadir Kaya, Gonul Buyukyilmaz, Huseyin Demirbilek
OBJECTIVE: There are a few number of case reports and small-scale case series reporting dilated cardiomyopathy due to vitamin D-deficient rickets. The present study evaluates the clinical, biochemical, and echocardiographic features of neonates with vitamin D deficiency. PATIENTS AND METHODS: In this prospective single-arm observational study, echocardiographic evaluation was performed on all patients before vitamin D3 and calcium replacement. Following remission of biochemical features of vitamin D deficiency, control echocardiography was performed...
May 4, 2021: Cardiology in the Young
Jayashree Seethapathy, Prakash Boominathan, Ajith Kumar Uppunda, Binu Ninan
BACKGROUND: Very preterm infants are at a greater risk of developing neurodevelopmental impairments such as neuro-motor delays, vision and hearing deficits (Roze and Breart, 2004; Saigal and Doyle, 2008) [1,2]. The hearing difficulties in preterm infants vary depending on the co-morbid conditions. However, prematurity itself is considered as a risk factor that influence the functioning of auditory system. AIM: The current study aims to compare the DPOAEs in very preterm infants and term infants at 1 month, 3 months and 6 months of age (corrected age in preterm infants)...
April 28, 2021: International Journal of Pediatric Otorhinolaryngology
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