John T Lucas, Zachary R Abramson, Katherine Epstein, Cara E Morin, Alok Jaju, Jessica W Lee, Chang-Lung Lee, Ranganatha Sitaram, Stephan D Voss, Melissa M Hudson, Louis S Constine, Chia-Ho Hua
The Pediatric Normal Tissue Effects in the Clinic (PENTEC) consortium has made significant contributions to understanding and mitigating the adverse effects of childhood cancer therapy. This review addresses the role of diagnostic imaging in detecting, screening, and comprehending radiation therapy-related late effects in children, drawing insights from individual organ-specific PENTEC reports. We further explore how the development of imaging biomarkers for key organ systems, alongside technical advancements and translational imaging approaches, may enhance the systematic application of imaging evaluations in childhood cancer survivors...
June 1, 2024: International Journal of Radiation Oncology, Biology, Physics