Daniel M Zeitler, Camille Dunn, Seth R Schwartz, Jennifer L McCoy, Carmen Jamis, David H Chi, Donald M Goldberg, Samantha Anne
OBJECTIVE: Evaluate health-related quality of life (HR-QOL) benefits with cochlear implantation (CI) in children with unilateral sensorineural hearing loss (USNHL) versus bilateral sensorineural hearing loss (BSNHL). STUDY DESIGN: A cross-sectional survey of parents of children who underwent CI for USNHL and BSNHL. SETTING: Tertiary care academic centers. METHODS: The "Children with cochlear implants: parental perspectives" survey was administered...
March 19, 2023: Otolaryngology—Head and Neck Surgery
Cunera M C de Beaufort, Julia C Groenveld, Tara M Mackay, K Mariam Slot, Sjoerd A de Beer, Justin R de Jong, Joost van Schuppen, Carola J McDonald, Dewi P Bakker, Elske van den Berg, Caroline F Kuijper, Ramon R Gorter
PURPOSE: First, to assess the number of spinal cord anomalies (SCA), specifically tethered spinal cord (TSC) in patients with anorectal malformations (ARM), identified with spinal cord imaging (i.e. spinal cord US and/or MRI). Second, to report outcomes after TSC treatment. METHODS: A retrospective mono-center study was performed. All ARM patients born between January 2000 and December 2021 were included. Screening for SCA consisted of spinal cord US and/or MRI...
March 19, 2023: Pediatric Surgery International
Maria M E Jongsma, Lea M M Costes, Irma Tindemans, Martinus A Cozijnsen, Rolien H C Raatgreep, Merel van Pieterson, Yunlei Li, Johanna C Escher, Lissy de Ridder, Janneke N Samsom
BACKGROUND: Despite its efficacy, rational guidance for starting/stopping first-line biologic treatment in individual pediatric Crohn's disease (CD) patients is needed. We assessed how serum immune profiles before and after first-line infliximab (FL-IFX) or conventional (CONV) induction therapy associate with disease remission at week 52. MATERIAL AND METHODS: pre- (n=86), and 10-14 week post-treatment (n=84) sera were collected from patients with moderate-to-severe paediatric CD in the TISKids trial, randomised to FL-IFX (n=48; five 5 mg/kg infusions over 22 weeks) or CONV (n=43; exclusive enteral nutrition or oral prednisolone); both groups received azathioprine maintenance...
March 19, 2023: Journal of Crohn's & Colitis
Laetitia Lebrun, Sacha Allard-Demoustiez, Nathalie Gilis, Claude Van Campenhout, Marine Rodesch, Celine Roman, Pierluigi Calò, Valentina Lolli, Philippe David, Christophe Fricx, Olivier De Witte, Fabienne Escande, Claude-Alain Maurage, Isabelle Salmon
Central Nervous System (CNS) embryonal tumors represent a heterogeneous group of highly aggressive tumors occurring preferentially in children but also described in adolescents and adults. In 2021, the CNS World Health Organization (WHO) classification drastically changed the diagnosis of the other CNS embryonal tumors including new histo-molecular tumor types. Here, we report a pediatric case of a novel tumor type among the other CNS embryonal tumors classified within the methylation class "CNS Embryonal Tumor with BRD4-LEUTX Fusion"...
March 18, 2023: Acta Neuropathologica Communications
Yajie Zhang, Lina Lu, Ling Yang, Weihui Yan, Qun Yu, Jinye Sheng, Xiaomeng Mao, Yi Feng, Qingya Tang, Wei Cai, Ying Wang
BACKGROUND: In a cohort of hospitalized children with congenital heart disease (CHD), a new digital pediatric malnutrition screening tool as a mobile application was validated, and its effectiveness and clinical value were determined as a prospective study. METHODS AND RESULTS: Children with CHD (n = 1125) were screened for malnutrition risk. The incidence of risk and the differences among various age groups and types of CHD were characterized. The optimal threshold for the tool to determine if there is a risk of malnutrition is score 2, while the Youden index was 79...
March 18, 2023: BMC Pediatrics
Afif El-Khuffash, Rachel Mullaly, Patrick J McNamara
No abstract text is available yet for this article.
March 18, 2023: Pediatric Research
Carmina Erdei, Katherine A Bell, Aisling A Garvey, Clementine Blaschke, Mandy B Belfort, Terrie E Inder
BACKGROUND: Preterm birth adversely impacts brain development and contributes to neurodevelopmental impairment; the temporal lobe may be particularly vulnerable to the impact of very preterm (VP) birth. Yet, no prior magnetic resonance imaging (MRI) scoring system incorporated a method to quantify temporal lobe size in VP infants. METHODS: We developed and applied three metrics (temporal lobe length, extra-axial space, and temporal horn width) to quantify temporal lobe structure on term-equivalent brain MRIs obtained from 74 VP and 16 term infants...
March 18, 2023: Pediatric Research
Xander Jacquemyn, Shelby Kutty, Preeta Dhanantwari, William J Ravekes, Aparna Kulkarni
BACKGROUND: A diabetic intrauterine environment has been proposed as a potential etiological mechanism for in utero programming of cardiac disease, and is associated with impaired fetal cardiac function. We aimed to assess cardiac function in offspring of mothers with diabetes mellitus (ODM) and determine whether fetal cardiac abnormalities persist during follow-up. METHODS: Longitudinal observational study to evaluate and compare myocardial function in 40 ODM to age-matched control offspring (CO)...
March 18, 2023: Pediatric Research
Amar Murdeshwar, Sriram Krishnamurthy, Narayanan Parameswaran, Medha Rajappa, Bobbity Deepthi, Sudarsan Krishnasamy, Sachit Ganapathy, Pediredla Karunakar
BACKGROUND: There is paucity of information regarding the etiology and outcomes of Acute Kidney Disease (AKD) in children. METHODS: The objectives of this cohort study were to evaluate the etiology and outcomes of AKD; and analyze predictors of kidney survival (defined as free of CKD 2, 3a, 3b, 4 or 5). Patients aged 1 month to 18 years who developed AKD over a 4-year-period (January 2018-December 2021) were enrolled. Survivors were followed-up at the pediatric nephrology clinic, and screened for residual kidney injury...
March 18, 2023: Clinical and Experimental Nephrology
X N Zhong, Yja Tan, M Nakao, I L Chan, M L Heng, Sma Tan, Y L Ng, Jcm Lam
INTRODUCTION: Due to a national policy change in the management of unused platelet units from September 2018, there was a drastic increase in the number of platelet units wasted in our institution. METHODS: Using Quality Improvement (QI) tools, platelet wastages from pediatric heart surgeries was identified as a priority area to work on. An intervention based on the creation of 'Order Sets' for pediatric open-heart surgeries was implemented, standardizing standby platelet orders based on type of surgery and patient weight...
March 14, 2023: Transfusion and Apheresis Science
John M Masterson, Michael Zaliznyak, Peris R Castaneda, Aurash Naser-Tavakolian, Andrew L Freedman
BACKGROUND: Trainee autonomy has eroded over time as surgery has become more subspecialized and as attending oversight has increased, causing many trainees to seek additional fellowship training beyond residency. Less clear is whether there are cases that attendings view as "fellowship-level" or "privileged" cases in which resident-level trainees should not have high levels of autonomy due to complexity or high-stakes outcomes. OBJECTIVE: We sought to better understand current attitudes and practices with regards to trainee autonomy in hypospadias repair as it represents a high complexity procedure within pediatric urology...
March 5, 2023: Journal of Pediatric Urology
Ashkan Pourabhari Langroudi, Zahra Shokri Varniab, Behnam Nabavizadeh, Afarin Neishabouri, Abdol-Mohammad Kajbafzadeh
INTRODUCTION: There are various treatment options for symptomatic bladder diverticulum, including robotic-assisted laparoscopic bladder diverticulectomy, open and endoscopic techniques. But, to date, the optimal surgical technique remains unclear. OBJECTIVE: To present the preliminary long-term follow-up results of a novel technique of dextranomer/hyaluronic acid copolymer (Deflux) plus autologous blood injection for correction of hutch diverticulum in patients with concomitant vesicoureteral reflux (VUR)...
February 26, 2023: Journal of Pediatric Urology
Fereshteh Salimi-Jazi, Claire Abrajano, Razie Yousefi, Deanna Garza, Kyla Santos Dalusag, Akanksha Sabapaty, Talha Rafeeqi, Thomas Hui, Wendy Su, Claudia Mueller, Julie Fuchs, Bill Chiu
BACKGROUND: Hair at the gluteal cleft plays a key role in the development and recurrence of pilonidal disease (PD). We hypothesized that more hair reduction achieved using laser could correlate with lower chance of PD recurrence. METHODS: PD patients who underwent laser epilation (LE) were categorized by Fitzpatrick skin type, hair color, and hair thickness. Photos taken at LE sessions were compared to determine hair reduction amount. LE sessions completed prior to the recurrences were recorded...
February 25, 2023: Journal of Pediatric Surgery
Samuel Skinner, Kevin Verhoeff, Kieran Purich, Raveena Dhaliwal, Matt Strickland, Troy Perry
BACKGROUND: Graduate and fellowship training trends for Canadian pediatric surgeons remain uncharacterized. Similarly, updated workforce planning for pediatric surgeons is required. We aimed to characterize graduate degree and fellowship trends for Canadian pediatric surgeons, with modelling to inform workforce planning. METHODS: We performed a cross sectional observational study evaluating Canadian pediatric surgeons in January 2022. Surgeon demographics collected included year of medical degree (MD) conferment, MD location, fellowship location, and graduate degree achievement...
February 23, 2023: Journal of Pediatric Surgery
Satoshi Kimura, Kazuyoshi Shimizu, Yoshikazu Matsuoka, Tatsuo Iwasaki, Tomoyuki Kanazawa, Hiroshi Morimatsu
OBJECTIVES: The authors investigated the management of neuromuscular blocking agents (NMBAs) for pediatric patients after cardiac surgery, and compared the outcomes of patients who received prophylactic NMBA (pNMBA) infusions and patients without pNMBA infusions. DESIGN: A retrospective cohort study. SETTING: At a tertiary teaching hospital. PARTICIPANTS: Patients younger than 18, with congenital heart disease, who underwent cardiac surgery...
February 23, 2023: Journal of Cardiothoracic and Vascular Anesthesia
Caroline H Hu, Lucas J Ray, Donald S Bae, Charles A Goldfarb, Michelle A James, Ann E Van Heest
PURPOSE: Transverse deficiency (TD) and symbrachydactyly may be difficult to distinguish due to shared phenotypes and a lack of pathognomonic features. The 2020 Oberg-Manske-Tonkin classification update modified these anomalies to include "with ectodermal elements" for symbrachydactyly and "without ectodermal elements" for TD as a defining differentiating characteristic. The purpose of this investigation was to characterize ectodermal elements and the level of deficiency and to examine whether ectodermal elements versus the level of deficiency was a greater determining factor for Congenital Upper Limb Differences (CoULD) surgeons making the diagnosis...
March 16, 2023: Journal of Hand Surgery
Ananya Munjal, Nkanyezi Ferguson
Over the past few years, there have been concerted efforts to increase diversity in the field of dermatology. This has been achieved through the creation of Diversity, Equity, and Inclusion (DEI) initiatives in dermatology organizations that strive to provide resources and opportunities for trainees who are underrepresented in medicine. This article compiles the ongoing DEI initiatives in the American Academy of Dermatology, Women's Dermatologic Society, Association of Professors of Dermatology Society, Society for Investigative Dermatology, Skin of Color Society, American Society for Dermatologic Surgery, The Dermatology Section of the National Medical Association, and Society for Pediatric Dermatology...
April 2023: Dermatologic Clinics
Karina Grullon, Victoria Barbosa
Health disparities exist in marginalized patient populations throughout medical specialties, including in dermatology. It is important that the physician workforce reflect the diversity of the US population to address these disparities. At present, the dermatology workforce does not reflect the racial or ethnic diversity of the US population. The subspecialties of pediatric dermatology, dermatopathology, and dermatologic surgery are even less diverse than the dermatology workforce as a whole. Although women make up over half of the population of dermatologists, disparities still exists in areas such as compensation and presence in leadership positions...
April 2023: Dermatologic Clinics
Meredith R Hickson, Madeline Winters, Nina H Thomas, Monique M Gardner, Matthew P Kirschen, Vinay Nadkarni, Robert Berg, Beth S Slomine, Neethi P Pinto, Alexis Topjian
BACKGROUND: Survival following pediatric out-of-hospital cardiac arrest (OHCA) has improved over the past 2 decades but data on survivors' long-term outcomes are limited. We aimed to evaluate long-term outcomes in pediatric OHCA survivors more than one year after cardiac arrest. METHODS: OHCA survivors < 18 years old who received post-cardiac arrest care in the PICU at a single center between 2008 - 2018 were included. Parents of patients <18 years and patients ≥18 years at least one year after cardiac arrest completed a telephone interview...
March 16, 2023: Resuscitation
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