Navya N Kamath, Paulina A Kulesz, Jack M Fletcher, Amy J Houtrow, Amery Treble-Barna
PURPOSE: The purpose of this study was to evaluate associations of ethnicity and adaptive function with health-related quality of life (HRQOL) in youths with spina bifida myelomeningocele (SBM). METHODS: Participants included Hispanic (n = 75) and non-Hispanic White (n = 86) children and adolescents with SBM. Participants completed ratings of adaptive function and SBM-specific HRQOL. A series of linear multiple regression models was computed to investigate whether ethnicity moderates the relation between adaptive function and HRQOL...
November 25, 2022: Journal of Pediatric Rehabilitation Medicine
Tapas Bandyopadhyay, Arti Maria, Nagaratna Vallamkonda
PURPOSE: To assess the performance of premature infant oral motor intervention for transition from gavage to full spoon feeding in preterm infants. METHODS: Preterm neonates born between 28 + 0-32 + 6 weeks gestation (n = 32) were randomised into an intervention group (premature infant oral motor intervention) for five minutes twice a day along with routine care (n = 16) and a control group (routine care, n = 16) once they reached a feed volume of at least 150 ml/kg/day administered by gavage method...
November 21, 2022: Journal of Pediatric Rehabilitation Medicine
Cecily L Betz, Sharon M Hudson, Adam L Skura, Nithya D Rajeev, Kathryn A Smith, Alexander Van Speybroeck
PURPOSE: The purpose of this exploratory study was to investigate the types of academic and health-related accommodations provided to adolescents and emerging adults with spina bifida aged 9-20 years. METHODS: Data was extracted from the paper and electronic records of transition-age youth enrolled in the study. Four open ended items involved content analysis. RESULTS: The most frequently identified accommodation was enrollment in special education classes in 47...
November 21, 2022: Journal of Pediatric Rehabilitation Medicine
Meta N Eek, Annika Blomkvist, Karin Romberg
PURPOSE: This study aimed to describe brace use, progression of scoliosis, and surgery in children with cerebral palsy (CP) and spina bifida (SB) who were initially treated with a brace. METHODS: Medical records were retrospectively analysed for brace compliance, treatment complications, curve size measurements with and without the brace at both start and at follow-up, and number of patients undergoing spine surgery. RESULTS: Sixty-eight children were included (CP 47, SB 21), 37 of whom were girls, with a mean age at start of treatment of 11...
November 23, 2022: Journal of Pediatric Rehabilitation Medicine
Sandra Isabel Jiménez-Gayosso, Raúl Alberto Morales-Luckie, Norma Leticia Robles-Bermeo, César Tadeo Hernández-Martínez, Juan José Villalobos-Rodelo, Rosalina Islas-Zarazúa, José de Jesús Navarrete-Hernández, Nuria Patiño-Marín, Carlo Eduardo Medina-Solís, Gerardo Maupomé
BACKGROUND: Prefabricated metal crowns (PMCs) have been widely used in pediatric dentistry due to their great success in various clinical situations. However, it is important to know the local effects, such as changes in pH in the oral environment. OBJECTIVE: To evaluate the pH variations before and after placement of PMCs. METHODS: A quasi-experimental study (before and after) was performed with 32 pediatric patients who needed rehabilitation with PMCs at a pediatric dentistry clinic in a public university...
November 17, 2022: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
Łukasz Obrycki, Jędrzej Sarnecki, Michał Pac, Tadeusz Dereziński, Weronika Lewandowska, Janusz Feber, Mieczysław Litwin
BACKGROUND: Primary hypertension may lead to early vascular ageing. We aimed to evaluate differences between expected vascular age based on pulse wave velocity (PWV)/carotid intima-media thickness (cIMT) and actual chronological age (CHA) in adolescents with primary hypertension. METHODS: Three hundred and fifty-two children (median age of 15.5 years) with office hypertension and 64 normotensive healthy children of the same age underwent anthropometry, office and ambulatory blood pressure (BP), left ventricular mass index, cIMT, PWV, pulse wave analysis and biochemistry measurements...
November 3, 2022: Journal of Hypertension
Wu Huang, Sunqiang Hu, Chi Wang, Jin Xiao
BACKGROUND: The aim of this study is to analyze patterns of maxillofacial fractures in children and adolescent in southeast of China,in a period of 10 years. MATERIAL AND METHODS: In this retrospective study, the medical records of 162 hospitalized patients under 18 years old were analyzed in the Department of Oral and Maxillofacial Surgery, Stomatology Hospital of Wenzhou Medical University, China. Age, gender, etiology, site, and type of fracture, monthly distribution, weekly distribution, dental complications, and treatment were evaluated...
August 1, 2022: Journal of Craniofacial Surgery
Kaitlin Strumph, Kerry Morrone, Parmpreet Dhillon, Kevin Hsu, William Gomes, Ellen Silver, Daniel Lax, Qi Peng, Seon Kyu Lee, Deepa Manwani, William Mitchell
BACKGROUND: Degree of cerebrovascular stenosis in pediatric patients with sickle cell anemia (SCA) informs need for chronic transfusion therapy, which has significant risks. Flow artifact, intrinsic to magnetic resonance angiography (MRA), is dependent on technical parameters and can lead to overinterpretation of stenosis. The primary objective of this study was to document any change in stroke prevention therapy that could be attributed to the implementation of a standardized MRA scanning protocol for patients with SCA...
November 28, 2022: Pediatric Blood & Cancer
Beth McCarville
No abstract text is available yet for this article.
November 28, 2022: Pediatric Blood & Cancer
Thomas Björk-Eriksson, Martina Boström, Ing-Liss Bryngelsson, Päivi M Lähteenmäki, Marianne Jarfelt, Marie Kalm, Daniel S Olsson
IMPORTANCE: Acute lymphoblastic leukemia (ALL) constitutes 20% to 30% of all pediatric cancers. The 5-year overall survival among pediatric patients with ALL in high-income countries such as Sweden is currently more than 90%, but long-term unselected nationwide mortality data and mortality data in relation to the general population are lacking. OBJECTIVE: To compare mortality between pediatric patients with ALL and the general population during a 30-year period in Sweden and to assess the incidence of ALL in Sweden...
November 1, 2022: JAMA Network Open
Asma Ahmed, Laura C Rosella, Maryam Oskoui, Tristan Watson, Seungmi Yang
IMPORTANCE: Although maternal unintentional injury during pregnancy has shown negative impacts on the mother and fetus, the evidence on its long-term associations with children's neurodevelopment is limited. OBJECTIVE: To examine the association between maternal unintentional injury and cerebral palsy (CP) in offspring. DESIGN, SETTING, AND PARTICIPANTS: This was a population-based, longitudinal, cohort study of all in-hospital live births born between April 1, 2002, and March 31, 2017, in a publicly funded health care system setting of Ontario, Canada...
November 28, 2022: JAMA Pediatrics
Cinnamon A Dixon, Tammara Jenkins, Valerie Maholmes
No abstract text is available yet for this article.
November 28, 2022: JAMA Pediatrics
Zeyan Liew, Haoran Zhuo
No abstract text is available yet for this article.
November 28, 2022: JAMA Pediatrics
Davaasambuu Ganmaa, Sabri Bromage, Polyna Khudyakov, Sumiya Erdenenbaatar, Baigal Delgererekh, Adrian R Martineau
IMPORTANCE: Vitamin D deficiency (defined as 25-hydroxyvitamin D [25(OH)D] <20 ng/mL) is prevalent among children living in temperate climates and has been reported to associate independently with stunting, obesity, and early activation of the hypothalamic-pituitary-gonadal axis. Phase 3 randomized clinical trials to investigate the influence of long-term vitamin D replacement on growth, body composition, and pubertal development of school-aged children with vitamin D deficiency are lacking...
November 28, 2022: JAMA Pediatrics
Xiaolong Xie, Kewei Li, Bo Xiang
Perforated choledochal cysts is usually treated by open approach through a one- or two-stage procedure. Laparoscopic procedures are gradually being used more commonly with advancements in minimally invasive technology, while the level of difficulty and conversion rate are still high due to adhesions and deranged anatomy. Robot-assisted choledochal cyst excisions have been proposed as another minimally invasive procedure that is thought to improve operability and precision compared with laparoscopic surgery...
November 28, 2022: Updates in Surgery
Laíse Figueiredo de Oliveira, Gabriela Godoy Poluceno, Tuane Bazanella Sampaio, Leandra Celso Constantino, Ana Paula Costa, Wagner Carbolin Martins, Tharine Dal-Cim, Karen Andrinéia de Oliveira, Fabiana Kalyne Ludka, Rui Daniel Prediger, Frederico C Pereira, Carla Inês Tasca
Neonatal exposure to general anesthetics has been associated with neurotoxicity and morphologic changes in the developing brain. Isoflurane is a volatile anesthetic widely used in pediatric patients to induce general anesthesia, analgesia, and perioperative sedation. In the present study, we investigated the effects of a single neonatal isoflurane (3% in oxygen, 2 h) exposure in rats at postnatal day (PND) 7, in short-term (24 h - PND8) and long-term (adulthood) protocols. In PND8, ex vivo analysis of hippocampal and frontal cortex slices evaluated cell viability and susceptibility to in vitro glutamate challenge...
November 28, 2022: Neurotoxicity Research
Nimet Öner, Elif Çelikel, Zahide Ekici Tekin, Vildan Güngörer, Tuba Kurt, Pakize Nilüfer Tekgöz, Müge Sezer, Cüneyt Karagöl, Serkan Coşkun, Melike Mehveş Kaplan, Merve Cansu Polat, Banu Çelikel Acar
OBJECTIVE: The aim of this study is to evaluate the outcomes of patients who received intravenous immunoglobulin (IVIG) for immunoglobulin A vasculitis (IgAV) with gastrointestinal (GI) tract involvement, and to determine the differences between the groups that responded to IVIG and those that did not. METHODS: This retrospective study comprised 152 patients with IgAV between 2018 and 2022. Sixty-five patients (43%) had GI tract involvement. Patients with IgAV-GI involvement who had been treated with IVIG were evaluated...
November 28, 2022: Clinical and Experimental Medicine
Walter E Kaufmann, Melissa Raspa, Carla M Bann, Julia M Gable, Holly K Harris, Dejan B Budimirovic, Reymundo Lozano
Fragile X syndrome (FXS) is characterized by variable neurobehavioral abnormalities, which leads to difficulties in developing and evaluating treatments and in determining accurate prognosis. We employed a pediatric cross-sectional sample (1,072 males, 338 females) from FORWARD, a clinic-based natural history study, to identify behavioral subtypes by latent class analysis. Input included co-occurring behavioral conditions, sleep and sensory problems, autistic behavior scales (SCQ, SRS-2), and the Aberrant Behavior Checklist revised for FXS (ABCFX )...
November 28, 2022: Journal of Autism and Developmental Disorders
Hui Jin Shin, Ji-Hoon Na, Hyunjoo Lee, Young-Mock Lee
BACKGROUND: This study investigated the efficacy and safety of nusinersen, an antisense oligonucleotide, in patients with spinal muscular atrophy (SMA) types II (OMIM: 253,550) or III (OMIM: 253,400), including those with severe scoliosis or requiring respiratory support via mechanical ventilation. METHODS: Data from 40 patients with genetically confirmed SMA who were treated with nusinersen at our institute from March 2019 to April 2022 were retrospectively analyzed...
November 28, 2022: World Journal of Pediatrics: WJP
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