Chukwuebuka Egbuna, Chinaza G Awuchi, Garima Kushwaha, Mithun Rudrapal, Kingsley C Patrick-Iwuanyanwu, Omkar Singh, Uchenna E Odoh, Johra Khan, Jaison Jeevanandam, Suresh Kumarasamy, Vincent O Chukwube, Mathiyazhagan Narayanan, Santwana Palai, Mihnea-Alexandru Găman, Chukwuemelie Z Uche, Daprim S Ogaji, Nebechi J Ezeofor, Andrew G Mtewa, Chinyere C Patrick-Iwuanyanwu, Shyam S Kesh, Chandan Shivamallu, Kaliyaperumal Saravanan, Habibu Tijjani, Muhammad Akram, Jonathan C Ifemeje, Michael C Olisah, Chukwudi J Chikwendu
BACKGROUND: Type 2 diabetes (adult onset diabetes) is the most common type of diabetes, accounting for around 90% of all diabetes cases with insulin resistance and insulin secretion defect. The key goal of anti-diabetic therapy is to increase the development of insulin, immunity and/or decrease the amount of blood glucose. While many synthetic compounds have been produced as antidiabetic agents, due to their side effects and limited effectiveness, their usefulness has been hindered. METHODS: This systematic review investigated the bioactive compounds reported to possess activities against type 2 diabetes...
2021: Current Topics in Medicinal Chemistry