Kamran Zaman, Anita M Shete, Shailendra Kumar Mishra, Abhinendra Kumar, Mahendra M Reddy, Rima R Sahay, Shailendra Yadav, Triparna Majumdar, Ashok K Pandey, Gaurav Raj Dwivedi, Hirawati Deval, Rajeev Singh, Sthita Pragnya Behera, Niraj Kumar, Savita Patil, Ashish Kumar, Manisha Dudhmal, Yash Joshi, Aishwarya Shukla, Pranita Gawande, Asif Kavathekar, Nalin Kumar, Vijay Kumar, Kamlesh Kumar, Ravi Shankar Singh, Manoj Kumar, Shashikant Tiwari, Ajay Verma, Pragya D Yadav, Rajni Kant
BACKGROUND: Recent studies on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reveal that Omicron variant BA.1 and sub-lineages have revived the concern over resistance to antiviral drugs and vaccine-induced immunity. The present study aims to analyze the clinical profile and genome characterization of the SARS-CoV-2 variant in eastern Uttar Pradesh (UP), North India. METHODS: Whole-genome sequencing (WGS) was conducted for 146 SARS-CoV-2 samples obtained from individuals who tested coronavirus disease 2019 (COVID-19) positive between the period of 1 January 2022 and 24 February 2022, from three districts of eastern UP...
2022: Frontiers in Medicine