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stomach neoplasm

Magdalena Olszewska-Szopa, Tomasz Wróbel
Although gastrointestinal (GI) tract is the most common extranodal site involved in non-Hodgkin lymphoma (NHL), primary gastrointestinal NHL (gNHL) is a rare problem which concerns about 10-15% of NHL patients and 30-40% of extranodal NHL patients. Lymphoid neoplasms may consist of mature B, T and (less commonly) extranodal NK/T cells. The most common diagnoses are diffuse large B-cell lymphoma and marginal zone lymphoma (MALT), but many other lymphomas may be found in the GI tract. There are a few well-known risk factors of gNHL and some of them affect treatment...
August 13, 2019: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Kaoru Nakano, Hiroshi Kawachi, Akiko Chino, Mizuho Kita, Masami Arai, Daisuke Ide, Shoichi Saito, Shoichi Yoshimizu, Yusuke Horiuchi, Akiyoshi Ishiyama, Toshiyuki Yoshio, Toshiaki Hirasawa, Tomohiro Tsuchida, Junko Fujisaki
OBJECTIVES: Gastric neoplasms (GNs), including gastric adenoma and carcinoma, are well known as extracolonic manifestations of familial adenomatous polyposis (FAP). We aimed to investigate the clinicopathological features of GNs in FAP patients and to clarify their relationship with the endoscopic status of the background mucosa. METHODS: We analyzed the records of 39 patients who were diagnosed with FAP and underwent esophagogastroduodenoscopy between April 2005 and July 2016...
August 14, 2019: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Janet C Guzmán-López, Leonardo S Lino-Silva, Rosa A Salcedo-Hernández, César Zepeda-Najar
Primary gastric choriocarcinomas (PGC) are very rare and aggressive neoplasms with a worrisome prognosis. Most cases are reported in Asia and presented in middle-aged adults with male predominance. Most cases are associated with an intestinal adenocarcinoma; however, the pathogenesis of this tumor is uncertain. No previous reports exist of the characteristics of the non-tumoral stomach in these patients, and this data that could help to clarify their pathogenesis. We presented a series of three cases of PGC in Latin American patients, emphasizing the characteristics of non-neoplastic mucosa...
August 2019: Journal of Gastrointestinal Oncology
Tetsuo Ushiku, Akiko Kunita, Ryohei Kuroda, Aya Shinozaki-Ushiku, Sho Yamazawa, Yosuke Tsuji, Mitsuhiro Fujishiro, Masashi Fukayama
Gastric neoplasms exhibiting oxyntic gland differentiation typically are composed of cells with mild cytonuclear atypia differentiating to chief cells and to a lesser extent, parietal cells. Such tumors with atypical features have been reported also and terminology for this entity remains a matter of considerable debate. We analyzed and classified 26 tumors as oxyntic gland neoplasms within mucosa (group A, eight tumors) and with submucosal invasion. The latter was divided further into those with typical histologic features (group B, 14 tumors) and atypical features, including high-grade nuclear or architectural abnormality and presence of atypical cellular differentiation (group C, four tumors)...
August 2, 2019: Modern Pathology
Jad A Degheili, Pierre Sfeir, Ibrahim Khalifeh, Ali H Hallal
BACKGROUND: Gastrointestinal schwannomas are submucosal tumors accounting for 2-7% of mesenchymal gastro-intestinal neoplasms; the stomach being the most common site. Esophageal schwannomas are more frequent in women, and are usually located in the upper to mid portion. Dysphagia is the main presenting symptom. A definitive diagnosis requires confirmation by histopathological and immunohistochemical studies. CASE PRESENTATION: A 50-year-old healthy lady, presented with gradual increasing onset of dyspnea, with minimal dysphagia to solid food, over a period of several years...
July 19, 2019: International Journal of Surgery Case Reports
Dimitrios Papaconstantinou, Diamantis I Tsilimigras, Dimitrios Moris, Adamantios Michalinos, Aikaterini Mastoraki, Efstratia Mpaili, Natasha Hasemaki, Anargyros Bakopoulos, Dimitrios Filippou, Dimitrios Schizas
BACKGROUND: Neoplasms arising in the esophagus may coexist with other solid organ or gastrointestinal tract neoplasms in 6% to 15% of patients. Resection of both tumors synchronously or in a staged procedure provides the best chances for long-term survival. Synchronous resection of both esophageal and second primary malignancy may be feasible in a subset of patients; however, literature on this topic remains rather scarce. AIM: To analyze the operative techniques employed in esophageal resections combined with gastric, pancreatic, lung, colorectal, kidney and liver resections and define postoperative outcomes in each case...
July 14, 2019: World Journal of Gastroenterology: WJG
Josué Aliaga Ramos, Hugo Cedrón Cheng, José Pinto Valdivia
INTRODUCTION: Kaposi sarcoma is a low-grade angioproliferative neoplasm strongly associated with infection by herpes virus type 8 (HHV-8). Gastrointestinal (GI) involvement is an infrequent finding, whose clinical and endoscopic characteristics are poorly defined in the literature. OBJECTIVE: The aim of our study was to describe the clinical and endoscopic findings of patients with gastrointestinal Kaposi Sarcoma. MATERIALS AND METHODS: We reviewed all clinical histories, endoscopic and anatomopathologic reports of all patients with cutaneous Kaposi sarcoma (CKS) who came to Cayetano Heredia Gastroenterology Service during the period between August 2015 to October 2018...
April 2019: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
Hideki Izumi, Hisamichi Yoshii, Rin Abe, Masaya Mukai, Eiji Nomura, Hiroyuki Ito, Tomoko Sugiyama, Takuma Tajiri, Hiroyasu Makuuchi
BACKGROUND: Gastric duplication is a relatively rare congenital malformation, accounting for approximately 2.9-3.8% of gastrointestinal duplications. Gastric duplication cyst is a congenital anomaly that is rarely observed in adults. Accurate diagnosis of these cysts before resection is difficult. In this report, we describe a patient with gastric duplication cysts that were treated by laparoscopic resection. CASE PRESENTATION: A 46-year-old Japanese woman was referred to our institution because a cystic lesion in the pancreatic tail was detected by ultrasonography during a health examination...
July 19, 2019: Journal of Medical Case Reports
Young Kwon Choi, Do Hoon Kim, Eun Jeong Gong, Hee Kyong Na, Ji Yong Ahn, Kee Wook Jung, Jeong Hoon Lee, Kee Don Choi, Ho June Song, Hwoon-Yong Jung, Jeong Hwan Yook, Byung Sik Kim
BACKGROUND: Treatment of locally recurrent gastric neoplasms after endoscopic resection remains challenging. We investigated the efficacy and safety of treatment options for recurrent gastric neoplasms localized to the scar of previous endoscopic submucosal dissection (ESD). METHODS: The clinicopathological characteristics and treatment outcomes of patients who underwent endoscopic treatment or surgery for recurrent gastric neoplasms between June 2010 and May 2017 were retrospectively reviewed...
July 15, 2019: Journal of Gastrointestinal Surgery
Shayma Kazmi, Steven Wagner, Rebecca Heintzelman, Melanie Corbman
BACKGROUND: Lynch syndrome, or hereditary nonpolyposis colorectal cancer, is an autosomal dominant genetic syndrome that predisposes individuals to multiple cancer types. The known cancers associated with Lynch syndrome include colorectal and endometrial cancers as well as cancers of the stomach, ovary, urinary tract, hepatobiliary tract, pancreas, small bowel, and brain. There are no searchable cases of malignant phyllodes of the breast associated with Lynch syndrome. CASE PRESENTATION: Our patient was a 43-year-old Caucasian woman who felt a lump in her left breast and was found to have a spindle cell neoplasm...
July 16, 2019: Journal of Medical Case Reports
Kitti Wongta, Vorapatu Tangsirapat, Vichack Chakrapan Na Ayudhya, Papot Charutragulchai, Singha Sripreechapattana, Kobkool Chakrapan Na Ayudhya, Rapol Poolsavatkitikool, Paiboon Sookpotarom, Paisarn Vejchapipat
INTRODUCTION: Gastrointestinal stromal tumors (GISTs), although not common in gastrointestinal (GI) tumors, constitute the most frequent mesenchymal tumors of the GI tract. This report describes a patient with a large sporadic GIST at proximal jejunum that mimicked the pancreatic cystic neoplasm. CASE PRESENTATION: We report a 59-year-old female patient with unexplained weight loss and palpable left upper quadrant abdominal mass for 6 months. Computed tomography (CT) scan demonstrated a heterogeneously mass measuring 10 cm in a maximal diameter at pancreatic body and tail...
June 17, 2019: International Journal of Surgery Case Reports
Kosmas Daskalakis, Marina Tsoli, Angeliki Karapanagioti, Maria Chrysochoou, Dimitrios Thomas, Stavros Sougioultzis, Ioannis Karoumpalis, Gregory A Kaltsas, Krystallenia I Alexandraki
BACKGROUND: The aim of our study was to assess clinico-pathological and biochemical parameters of Type 1 Gastric Neuroendocrine Neoplasms (GNEN1) with respect to tumours propensity for recurrence and metastasis. METHODS: Hospital charts of GNEN1 patients were reviewed at a single tertiary referral centre. RESULTS: We included 114 consecutive patients (74 women; age at baseline 54.5 ± 12.7 years [mean ± SD]) with GNEN1. All tumours (n = 114) were well differentiated; Grade 1 (G1) accounted for 56 patients (49%), whereas 46 (40%) were Grade 2 (G2) and 12 (11%) of unknown Grade...
June 29, 2019: Clinical Endocrinology
Joo Hyun Lee, Jeong Kyun Lee, Dong Baek Kang
Choriocarcinoma is an aggressively growing and widely metastasizing tumor that originates from trophoblastic cells. A primary gastric choriocarcinoma (PGC), however, is very rare. A 76-year-old female patient visited the emergency department of Wonkwang University Hospital with abdominal discomfort and melena. Esophagogastroduodenoscopy revealed a huge ulceroinfiltrative mass lesion with blood clots on the boundary between the greater curvature side and the posterior wall side of the stomach lower body. CT showed a 3-cm exophytic mass lesion with heterogeneous enhancement, an ulcer lesion at the posterior wall side of the stomach lower body, and multiple enlarged lymph nodes at the splenic artery and left gastric artery nodal stations...
June 25, 2019: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
Evangelos Voudoukis, Afroditi Mpitouli, Konstantina Giannakopoulou, Magdalini Velegraki, Galateia Datseri, Maria Bachlitzanaki, Georgios Kazamias, Anthi Fahouridi, Emmanouil Mastorakis, Emmanouil Vardas, Emmanouil Kontopodis, Gregorios Paspatis
There is a wide variety of pancreatic neoplasms identified, but the great majority of them are of primary origin. Metastatic disease in the pancreatic parenchyma is quite rare (2-5% of pancreatic malignancies) and most often is quite difficult to differentiate from other primary lesions. Most of the imaging studies fail to give certain discriminating features for metastatic pancreatic neoplasms, contrary to endoscopic ultrasound and tissue sampling, which can provide an accurate diagnosis. In this report, we present a case of a male middle aged man who was admitted to our hospital with painless jaundice and finally was diagnosed with a cutaneous scalp melanoma dispersedly metastasized to the pancreas and upper gastrointestinal tract (stomach and duodenum)...
June 21, 2019: Clinical Journal of Gastroenterology
Eugenia Raffaeli, Luca Cardinali, Maurizio Fianchini, Donatella Brancorsini, Piergiorgio Mosca, Cristina Marmorale
INTRODUCTION: Inflammatory myofibroblastic tumor (IMT) is a rare proliferative disease of uncertain etiology, characterized by the proliferation of fusate or epithelioid myofibroblasts admixed with predominantly mononuclear inflammatory cells. IMT is generally considered a benign lesion, although in some cases this neoplasm has shown an aggressive behavior in terms of local recurrence and metastasis. We report the case of a patient with a ten-year history of ulcerative colitis affected by IMT of the transverse colon and by synchronous gastrointestinal stromal tumor (GIST) of stomach...
June 12, 2019: International Journal of Surgery Case Reports
Xiaocen Zhang, Erin K Ly, Sagarika Nithyanand, Rani J Modayil, Dmitriy O Khodorskiy, Sivaram Neppala, Sriya Bhumi, Matthew DeMaria, Jessica L Widmer, David M Friedel, James H Grendell, Stavros N Stavropoulos
BACKGROUND & AIMS: Endoscopic submucosal dissection (ESD) is widely used in Asia to resect early-stage gastrointestinal neoplasms, but use of ESD in Western countries is limited. We collected data on the learning curve for ESD at a high-volume referral center in the United States to guide development of training programs in the Americas and Europe. METHODS: We performed a retrospective analysis of consecutive ESDs performed by a single operator at a high-volume referral center in the United States from 2009 through 2017...
June 17, 2019: Clinical Gastroenterology and Hepatology
Leandro Cardoso Barchi, Willy Petrini Souza, Maurice Youssef Franciss, Marcus Fernando Kodama Pertille Ramos, Andre Roncon Dias, Woo Jin Hyung, Bruno Zilberstein
Robotic surgery through the da Vinci Surgical System has been widely spread for many procedures across the globe for several years. At the same time, robot-assisted gastrectomy for gastric cancer (GC) remains mostly available only in specialized centers in minimally invasive surgery and stomach neoplasm. The robotic platform has been introduced to overcome possible drawbacks of the laparoscopic approach. The safety and the feasibility of robotic radical gastrectomy have been reported in many retrospective case series and nonrandomized prospective studies...
June 20, 2019: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Y L Zhu, T Qiu, H F Zhang, J M Ying, H T Zhang
Objective: To analyze the clinicopathological features and differential diagnosis of interdigitating dendritic cell sarcoma (IDCS). Methods: The clinical pathological features of 7 IDCS were analyzed. Among them, the follow-up results of 6 cases were available. Results: Among the 7 IDCS patients, 4 cases were male and 3 were female. The age of the patients ranged from 26 to 69 years.Three cases were originated from lymph nodes and 4 cases were originated from skin, stomach, adrenal gland and mesentery, respectively...
June 23, 2019: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
Alyson S Cunningham, Ayesha S Siddique, Saverio Ligato, Paul V Vignati
Inflammatory fibroid polyps (IFP) are rare benign lesions arising from the submucosa of the gastrointestinal tract, most commonly found in the stomach and small intestine. IFPs are very rarely found in the rectum, with only a few reported cases, and their presentation is quite varied. The patient is a 53 year old male who underwent routine screening colonoscopy, during which a lobular mass of the proximal rectum was discovered. The patient subsequently underwent an endoscopic ultrasound (EUS) with fine needle aspiration (FNA) biopsy...
June 2019: Journal of Surgical Case Reports
Zhixian Lin, Jiangfeng Chen, Yong Guo
RATIONALE: Mixed adenoneuroendocrine carcinoma (MANEC) is a rare neoplasm, and consensus on the treatment is unavailable. PATIENT CONCERN: A 60-year-old Chinese man presented with obstructive symptoms while eating and paroxysmal stomach pain for more than a month. DIAGNOSIS: MANEC was diagnosed based on clinical manifestations, imaging findings, and pathological examinations. INTERVENTIONS: The patient underwent radical gastrectomy and received XELOX adjuvant chemotherapy (oxaliplatin 200 mg day 1 + capecitabine 1...
June 2019: Medicine (Baltimore)
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