Albert Powers, Philip Angelos, Alexandria Bond, Emily Farina, Carolyn Fredericks, Jay Gandhi, Maximillian Greenwald, Gabriela Hernandez-Busot, Gabriel Hosein, Megan Kelley, Catalina Mourgues, William Palmer, Julia Rodriguez-Sanchez, Rashina Seabury, Silmilly Toribio, Raina Vin, Jeremy Weleff, David Benrimoh
The mechanisms of psychotic symptoms like hallucinations and delusions are often investigated in fully-formed illness, well after symptoms emerge. These investigations have yielded key insights, but are not well-positioned to reveal the dynamic forces underlying symptom formation itself. Understanding symptom development over time would allow us to identify steps in the pathophysiological process leading to psychosis, shifting the focus of psychiatric intervention from symptom alleviation to prevention. We propose a model for understanding the emergence of psychotic symptoms within the context of an adaptive, developing neural system...
April 16, 2024: ArXiv