keyword
https://read.qxmd.com/read/37846725/genetic-diversity-population-structure-and-demographic-history-of-the-chilhuil-sea-catfish-bagre-panamensis-in-northwestern-mexico-inferred-from-mitochondrial-dna
#41
JOURNAL ARTICLE
Karla Isela Arroyo-Zúñiga, Jasmín Granados-Amores, Deivis Samuel Palacios-Salgado, Viridiana Peraza-Gómez, Fausto Valenzuela-Quiñonez
The chilhuil sea catfish ( Bagre panamensis ) is an ecologically relevant species contributing to the structure, organization, and functioning of the ecosystems it inhabits. Also, it is an important artisanal fishery resource in the Mexican Pacific coast. This study aimed to determine the genetic diversity, population structure, and historical demography of B. panamensis in the Mexican Pacific. The mitochondrial DNA was amplified from two distinct regions, r16S and COI, resulting in an 1142 bp of the concatenated genes...
October 17, 2023: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://read.qxmd.com/read/37835239/muffin-type-bakery-product-based-on-mexican-mesquite-prosopis-spp-flour-texture-profile-acceptability-and-physicochemical-properties
#42
JOURNAL ARTICLE
María Elizabeth Alemán-Huerta, Brenda A Castillo-Cázares, Julia Mariana Márquez-Reyes, Juan G Báez-González, Isela Quintero-Zapata, Fátima Lizeth Gandarilla-Pacheco, Erick de Jesús de Luna-Santillana, Mayra Z Treviño-Garza
In this research, muffin-type bakery products were developed based on wheat flour (WF) and mesquite flour (MF) in the following proportions: WFMF 90:10, WFMF 75:25, and WFMF 50:50. The products were characterized based on various properties in which it was possible to observe that the water activity (aw) did not show a significant change with the increase in the concentration of MF. In addition, the increase in the concentration of MF modified the sensory properties (color, odor, flavor, texture, and acceptance), further decreasing the luminosity and increasing the values of the a* and b* coordinates...
September 27, 2023: Foods (Basel, Switzerland)
https://read.qxmd.com/read/37792428/effect-of-blackberry-juice-consumption-by-pregnant-rats-on-brain-length-and-cell-density-of-dentate-gyrus-in-male-wistar-pups
#43
JOURNAL ARTICLE
Sigrid Mariel Ruiz-Martínez, Rosa Isela Guzmán-Gerónimo, Mayvi Alvarado-Olivarez, Isela Santiago-Roque, José Antonio Palma-Jacinto
The aim of this work was to evaluate the effect of blackberry juice consumption during pregnancy on the length of the brain, as well as on the cell density of the dentate gyrus in Wistar rat pups. Pregnant rats were divided into three groups: control (C), fed with standard diet and water ad libitum ; BJ1, which received blackberry juice containing polyphenols (7.8 mg/kg) and anthocyanins (1.9 mg/kg); and BJ2, receiving blackberry juice containing polyphenols (9.3 mg/kg) and anthocyanins (3...
October 4, 2023: Journal of Medicinal Food
https://read.qxmd.com/read/37763752/prevalence-of-poor-sleep-quality-and-associated-factors-in-individuals-with-rheumatoid-arthritis-a-cross-sectional-study
#44
JOURNAL ARTICLE
Isela Esther Juárez-Rojop, Ana Fresán, Alma Delia Genis-Mendoza, Carolina Cerino-Palomino, German Alberto Nolasco-Rosales, Thelma Beatriz González-Castro, María Lilia López-Narváez, Francisco Olan, Mario Villar-Soto, Carlos Alfonso Tovilla-Zárate, Humberto Nicolini
Background and Objectives : Poor sleep quality has been frequently observed in individuals with rheumatoid arthritis. In the present study, we analyzed the presence of poor sleep quality in a sample of Mexican individuals with rheumatoid arthritis; then, we compared sociodemographic and clinical characteristics among patients to determine risk factors for poor sleep quality. Materials and Methods : In this cross-sectional study, we included 102 individuals with rheumatoid arthritis from a hospital in Mexico...
September 8, 2023: Medicina
https://read.qxmd.com/read/37750053/strengthening-public-health-policies-for-childhood-cancer-peru-s-achievements-through-the-who-global-initiative-for-childhood-cancer
#45
JOURNAL ARTICLE
Essy Maradiegue, Claudia Pascual, Liliana Vasquez, Ivan Maza, Cecilia Ugaz, Jackeline Montoya, Arturo Zapata, Henry García, Sharon Chavez, Katy Ordoñez, Jonathan Rossi, Rosdali Diaz, Roxana Morales, Viviana Trigoso, Romy Ames, Edinho Celis, Isela Barzola, Liliana Torres, Melitta Cosme, Fanny Tarrillo, Ninoska Rojas, Carlos Santillan, Yuly Quispe, Víctor Palacios, Victoria Godoy, Mariela Tello, Duniska Tarco, Antonio Wachtel, Estela Malaver, Elizabeth Diaz, Marlene Goyburu, Vivian Perez, Ivy Talavera, Maria Edith Baca, Mauricio Maza, Lily Saldaña, Alexis Holguin, Marta Jarquin, Patricia Loggetto, Monika Metzger, Paola Friedrich, Cath Lam, Carlos Rodriguez Galindo
OBJECTIVE: To report the progress in Peru, since June 2019, in the implementation of the World Health Organization Global Initiative for Childhood Cancer using the Cure All framework, which can be replicated in low- and middle-income countries. METHODS: A mixed method was used of participatory and documentary evaluation. The participatory evaluation included stakeholders from various government institutions, nonprofit organizations, and international partners. The documentary aspect consisted of a review of data on the regulatory environment, national projects, and interventions implemented...
2023: Pan American Journal of Public Health
https://read.qxmd.com/read/37741477/%C3%AE-glucuronidase-as-a-biomarker-for-assessing-the-exposure-to-anticholinergic-pesticides-a-meta-analysis
#46
REVIEW
Jesús Isimar Serafín-Fabian, Ma Elena Moreno-Godínez, Eugenia Flores-Alfaro, Isela Parra-Rojas, Aurora Elizabeth Rojas-García, Gabriela Elizabeth Campos-Viguri, José Ángel Cahua-Pablo, Marco Antonio Ramírez-Vargas
INTRODUCTION: The human exposure to anticholinergic pesticides has been associated with the development of various diseases. Therefore, several biomarkers have been proposed for biomonitoring human exposure to anticholinergic pesticides. OBJECTIVE: This work evaluated the effect of human exposure to anticholinergic pesticides on β-glucuronidase (GUSB) levels. METHODS: A systematic review was performed using PubMed, Web of Science, Scopus, and EBSCO databases up to December 2021...
September 21, 2023: Environmental Toxicology and Pharmacology
https://read.qxmd.com/read/37671104/barriers-to-methamphetamine-treatment-seeking-in-residential-centers-in-aguascalientes-mexico
#47
JOURNAL ARTICLE
Kalina Isela Martínez Martínez, Yancarlo Lizandro Ojeda Aguilar, Lorenia Robles Villarreal, María Abigail Paz Pérez
INTRODUCTION: In the Aguascalientes, most people who seek treatment go to non-governmental residential centers, and about half request treatment for meth use. Although some barriers to treatment seeking among these users are known, few studies have been conducted with the Mexican population, specifically with users of residential centers. The aim of this study was to explore the main barriers reported by these patients, the relationship between reported barriers and meth use, as well as identify possible user profiles based on the barriers and the pattern of consumption...
2023: Frontiers in Psychology
https://read.qxmd.com/read/37659997/-when-you-leave-your-country-this-is-what-you-re-in-for-experiences-of-structural-legal-and-gender-based-violence-among-asylum-seeking-women-at-the-mexico-u-s-border
#48
JOURNAL ARTICLE
Kaylee Ramage, Emma Stirling-Cameron, Nicole Elizabeth Ramos, Isela Martinez SanRoman, Ietza Bojorquez, Arianna Spata, Brigitte Baltazar Lujano, Shira M Goldenberg
BACKGROUND: Recent U.S. immigration policy has increasingly focused on asylum deterrence and has been used extensively to rapidly deport and deter asylum-seekers, leaving thousands of would-be asylum-seekers waiting indefinitely in Mexican border cities, a large and growing proportion of whom are pregnant and parenting women. In the border city of Tijuana, Mexico, these women are spending unprecedented durations waiting under unsafe humanitarian conditions to seek safety in the U.S, with rising concerns regarding increases in gender-based violence (GBV) among this population during the COVID-19 pandemic...
September 2, 2023: BMC Public Health
https://read.qxmd.com/read/37630479/-cd147-rs8259t-a-variant-confers-susceptibility-to-covid-19-infection-within-the-mexican-population
#49
JOURNAL ARTICLE
Luis M Amezcua-Guerra, Carlos A Guzmán-Martín, Isela Montúfar-Robles, Rashidi Springall, Adrián Hernández-Díazcouder, Rosa Elda Barbosa-Cobos, Fausto Sánchez-Muñoz, Julián Ramírez-Bello
BACKGROUND: Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clinical manifestations of COVID-19 range from mild flu-like symptoms to severe respiratory failure. Nowadays, extracellular matrix metalloproteinase inducer (EMMPRIN), also known as cluster of differentiation 147 (CD147) or BASIGIN, has been studied as enabling viral entry and replication within host cells. However, the impact of the CD147 rs8259T>A single nucleotide variant (SNV) on SARS-CoV-2 susceptibility remains poorly investigated...
July 28, 2023: Microorganisms
https://read.qxmd.com/read/37623851/anti-inflammatory-potential-of-pteropodine-in-rodents
#50
JOURNAL ARTICLE
Rogelio Paniagua-Pérez, Laura Sánchez-Chapul, Eduardo Madrigal-Bujaidar, Isela Álvarez-González, Eduardo Madrigal-Santillán, Lidia Cruz-Hernández, Carlos Martínez-Canseco, Celia Reyes-Legorreta, Lidia Ruiz-Rosano, Cecilia Hernández-Flores, Rene Valdez-Mijares, Alejandra Quintana-Armenta
Pteropodine (PT) is a component of some plants with potentially useful pharmacological activities for humans. This compound has biomedical properties related to the modulation of the immune system, nervous system, and inflammatory processes. This study addresses the anti-inflammatory and antioxidant capacity of pteropodin in a murine model of arthritis and induced edema of the mouse ear. To evaluate the anti-inflammatory activity, we used the reversed passive Arthus reaction (RPAR), which includes the rat paw edema test, the rat pleurisy test, and a mouse ear edema model...
August 3, 2023: Metabolites
https://read.qxmd.com/read/37524705/knowledge-based-mechanistic-modeling-accurately-predicts-disease-progression-with-gefitinib-in-egfr-mutant-lung-adenocarcinoma
#51
JOURNAL ARTICLE
Adèle L'Hostis, Jean-Louis Palgen, Angélique Perrillat-Mercerot, Emmanuel Peyronnet, Evgueni Jacob, James Bosley, Michaël Duruisseaux, Raphaël Toueg, Lucile Lefèvre, Riad Kahoul, Nicoletta Ceres, Claudio Monteiro
Lung adenocarcinoma (LUAD) is associated with a low survival rate at advanced stages. Although the development of targeted therapies has improved outcomes in LUAD patients with identified and specific genetic alterations, such as activating mutations on the epidermal growth factor receptor gene (EGFR), the emergence of tumor resistance eventually occurs in all patients and this is driving the development of new therapies. In this paper, we present the In Silico EGFR-mutant LUAD (ISELA) model that links LUAD patients' individual characteristics, including tumor genetic heterogeneity, to tumor size evolution and tumor progression over time under first generation EGFR tyrosine kinase inhibitor gefitinib...
July 31, 2023: NPJ Systems Biology and Applications
https://read.qxmd.com/read/37516932/evaluation-of-the-cytotoxicity-and-genotoxicity-of-glufosinate-ammonium-at-technical-and-commercial-grades-in-hepg2-cells
#52
JOURNAL ARTICLE
Ezeidy Denisse Gallardo-Valle, Dayanne Carbajal-Nogueda, Ma Elena Moreno-Godínez, Eugenia Flores-Alfaro, Isela Parra-Rojas, Gerardo Huerta-Beristain, Teresa Domínguez-Reyes, Marco Antonio Ramírez-Vargas
Exposure to genotoxic agents is associated with the development of cancer and related diseases. For this reason, assessing the genotoxicity of chemical compounds is necessary. In this line, information about the genotoxic effect of glufosinate-ammonium (GLA) has been reported only for the technical grade. However, humans are frequently exposed to commercial formulations of pesticides. Commercial formulations are characterized by using inner agents that increase toxicity compared to pesticides in technical grade...
July 30, 2023: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
https://read.qxmd.com/read/37511627/sarcospan-deficiency-increases-oxidative-stress-and-arrhythmias-in-hearts-after-acute-ischemia-reperfusion-injury
#53
JOURNAL ARTICLE
Hyun Seok Hwang, Aida Rahimi Kahmini, Julia Prascak, Alexis Cejas-Carbonell, Isela C Valera, Samantha Champion, Mikayla Corrigan, Florence Mumbi, Michelle S Parvatiyar
The protein sarcospan (SSPN) is an integral member of the dystrophin-glycoprotein complex (DGC) and has been shown to be important in the heart during the development and the response to acute stress. In this study, we investigated the role of SSPN in the cardiac response to acute ischemia-reperfusion (IR) injury in SSPN-deficient (SSPN-/- ) mice. First, the hemodynamic response of SSPN-/- mice was tested and was similar to SSPN+/+ (wild-type) mice after isoproterenol injection. Using the in situ Langendorff perfusion method, SSPN-/- hearts were subjected to IR injury and found to have increased infarct size and arrhythmia susceptibility compared to SSPN+/+ ...
July 24, 2023: International Journal of Molecular Sciences
https://read.qxmd.com/read/37501620/strategies-of-diaspore-dispersal-investment-in-compositae-the-case-of-the-andean-highlands
#54
JOURNAL ARTICLE
Carolina Tovar, Lucia Hudson, Francisco Cuesta, Rosa Isela Meneses, Priscilla Muriel, Oriane Hidalgo, Luis Palazzesi, Carlos Suarez Ballesteros, Eleanor Hammond Hunt, Mauricio Diazgranados, D J Nicholas Hind, Félix Forest, Stephan Halloy, Nikolay Aguirre, William J Baker, Stephan Beck, Julieta Carilla, Paúl Eguiguren, Elaine Françoso, Luis E Gámez, Ricardo Jaramillo, Luis Daniel Llambí, Olivier Maurin, Inga Melcher, Gemma Muller, Shyamali Roy, Paul Viñas, Karina Yager, Juan Viruel
BACKGROUND AND AIMS: Understanding diaspore morphology and how much a species invests on dispersal appendages is key for improving our knowledge of dispersal in fragmented habitats. We investigate diaspore morphological traits in high-Andean Compositae, their main abiotic and biotic drivers and test whether they play a role in species distribution patterns across the naturally fragmented high-Andean grasslands. METHODS: We collected diaspore trait data for 125 Compositae species across 47 tropical high-Andean summits, focusing on achene length and pappus-to-achene length ratio, the latter as a proxy of dispersal investment...
July 28, 2023: Annals of Botany
https://read.qxmd.com/read/37482299/consensus-document-on-acute-on-chronic-liver-failure-aclf-established-by-the-mexican-association-of-hepatology
#55
Aldo Torre, Laura Esthela Cisneros-Garza, Mauricio Castillo-Barradas, Nalu Navarro-Alvarez, Ricardo Sandoval-Salas, María Sarai González-Huezo, José Luís Pérez-Hernández, Osvely Méndez-Guerrero, Jesús Alejandro Ruiz-Manríquez, Rafael Trejo-Estrada, Norberto C Chavez-Tapia, Luis Carlos Solís-Gasca, Carlos Moctezuma-Velázquez, Jonathan Aguirre-Valádez, Judith Flores-Calderón, Fatima Higuera-de-la-Tijera, Ignacio García-Juárez, Nancy Allin Canedo-Castillo, René Malé-Velázquez, Iaarah Montalvo-Gordon, Mario Vilatobá, Ernesto Márquez-Guillén, Jacqueline Córdova-Gallardo, Nayeli Cointa Flores-García, Godolfino Miranda-Zazueta, Belinda Isela Martínez-Saldívar, Víctor Manuel Páez-Zayas, Linda Elsa Muñoz-Espinosa, Francisco Alfonso Solís-Galindo
Acute-on chronic liver failure (ACLF) has been an intensively debated topic mainly due to the lack of a unified definition and diagnostic criteria. The growing number of publications describing the mechanisms of ACLF development, the progression of the disease, outcomes and treatment has contributed to a better understanding of the disease, however, it has also sparked the debate about this condition. As an attempt to provide medical professionals with a more uniform definition that could be applied to our population, the first Mexican consensus was performed by a panel of experts in the area of hepatology in Mexico...
July 22, 2023: Annals of Hepatology
https://read.qxmd.com/read/37448978/bringing-micro-to-the-macro-how-citizen-science-data-enrich-geospatial-visualizations-to-advance-health-equity
#56
JOURNAL ARTICLE
Shamsi Soltani, Jessica A Hinman, Isela Blanco-Velazquez, Ann W Banchoff, Maria I Campero, Lorene M Nelson, Abby C King
Social and spatial contexts affect health, and understanding nuances of context is key to informing successful interventions for health equity. Layering mixed methods and mixed scale data sources to visualize patterns of health outcomes facilitates analysis of both broad trends and person-level experiences across time and space. We used micro-scale citizen scientist-collected data from four Bay Area communities along with aggregate epidemiologic and population-level data sets to illustrate barriers to, and facilitators of, physical activity in low-income aging adults...
2023: Journal of Maps
https://read.qxmd.com/read/37446980/-bacillus-cabrialesii-five-years-of-research-on-a-novel-species-of-biological-control-and-plant-growth-promoting-bacteria
#57
REVIEW
Karem Ma Figueroa-Brambila, Alina Escalante-Beltrán, Amelia Cristina Montoya-Martínez, Alondra María Díaz-Rodríguez, Naomi Dayanna López-Montoya, Fannie Isela Parra-Cota, Sergio de Los Santos-Villalobos
Bacillus cabrialesii is a novel bacterial species isolated from wheat ( Triticum turgidum L. subsp. durum ) plants in the Yaqui Valley, Mexico, by our research team. Over years of research studying this strain at the cutting-edge level, it has shown different mechanisms of action. B. cabrialesii is strongly reported as a plant-growth-promoting bacterium and a biological control agent on wheat crops. Knowing this, B. cabrialesii has been brought from lab to field as part of a bacterial consortium, not to mention that there are ongoing investigations into formulating a cost-effective bioinoculant to increase the yield and/or quality of wheat...
June 22, 2023: Plants (Basel, Switzerland)
https://read.qxmd.com/read/37375942/chemopreventive-effect-of-cooked-chickpea-on-colon-carcinogenesis-evolution-in-aom-dss-induced-balb-c-mice
#58
JOURNAL ARTICLE
María Stephanie Cid-Gallegos, Cristian Jiménez-Martínez, Xariss M Sánchez-Chino, Eduardo Madrigal-Bujaidar, Verónica R Vásquez-Garzón, Rafael Baltiérrez-Hoyos, Isela Álvarez-González
Chickpeas are one of the most widely consumed legumes worldwide and they might prevent diseases such as cancer. Therefore, this study evaluates the chemopreventive effect of chickpea ( Cicer arietinum L.) on the evolution of colon carcinogenesis induced with azoxymethane (AOM) and dextran sodium sulfate (DSS) in a mice model at 1, 7, and 14 weeks after induction. Accordingly, the expression of biomarkers-such as argyrophilic nucleolar organizing regions (AgNOR), cell proliferation nuclear antigen (PCNA), β-catenin, inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2)-was assessed in the colon of BALB/c mice fed diets supplemented with 10 and 20% cooked chickpea (CC)...
June 14, 2023: Plants (Basel, Switzerland)
https://read.qxmd.com/read/37371712/mechanisms-of-action-and-limitations-of-monoclonal-antibodies-and-single-chain-fragment-variable-scfv-in-the-treatment-of-cancer
#59
REVIEW
Cynthia Rodríguez-Nava, Carlos Ortuño-Pineda, Berenice Illades-Aguiar, Eugenia Flores-Alfaro, Marco Antonio Leyva-Vázquez, Isela Parra-Rojas, Oscar Del Moral-Hernández, Amalia Vences-Velázquez, Karen Cortés-Sarabia, Luz Del Carmen Alarcón-Romero
Monoclonal antibodies are among the most effective tools for detecting tumor-associated antigens. The U.S. Food and Drug Administration (FDA) has approved more than 36 therapeutic antibodies for developing novel alternative therapies that have significant success rates in fighting cancer. However, some functional limitations have been described, such as their access to solid tumors and low interaction with the immune system. Single-chain variable fragments (scFv) are versatile and easy to produce, and being an attractive tool for use in immunotherapy models...
June 1, 2023: Biomedicines
https://read.qxmd.com/read/37371384/gene-expression-analysis-in-postmortem-brains-from-individuals-who-died-by-suicide-a-systematic-review
#60
REVIEW
Thelma Beatriz González-Castro, Alma Delia Genis-Mendoza, María Lilia López-Narváez, Isela Esther Juárez-Rojop, Miguel Angel Ramos-Méndez, Carlos Alfonso Tovilla-Zárate, Humberto Nicolini
Around the world, more the 700,000 individuals die by suicide every year. It is necessary to understand the mechanisms associated with suicidal behavior. Recently, an increase in gene expression studies has been in development. Through a systematic review, we aimed to find a candidate gene in gene expression studies on postmortem brains of suicide completers. Databases were systematically searched for published studies. We performed an online search using PubMed, Scopus and Web of Science databases to search studies up until May 2023...
June 3, 2023: Brain Sciences
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