Peter J K Tokuda, Takamasa Mitsuyoshi, Yuka Ono, Takahiro Kishi, Yoshiharu Negoro, Setsuko Okumura, Itaru Ikeda, Takashi Sakamoto, Yumi Kokubo, Ryo Ashida, Toshiyuki Imagumbai, Mikiko Yamashita, Hiroaki Tanabe, Sayaka Takebe, Mariko Tokiwa, Eiji Suzuki, Chikako Yamauchi, Michio Yoshimura, Takashi Mizowaki, Masaki Kokubo
BACKGROUND: The applicability of ultra-hypofractionated (ultra-HF) whole-breast irradiation (WBI) remains unknown in Japanese women. This study aimed to evaluate the safety and efficacy of this approach among Japanese women and report the results of an interim analysis performed to assess acute adverse events (AEs) and determine whether it was safe to continue this study. METHODS: We enrolled Japanese women with invasive breast cancer or ductal carcinoma in situ who had undergone breast-conserving surgery, were aged ≥ 40 years, had pathological stages of Tis-T3 N0-N1, and had negative surgical margins...
April 12, 2024: Breast Cancer: the Journal of the Japanese Breast Cancer Society