Varun S Shah, David Dornbos, Nguyen Alex Hoang, Santino Cua, Brandon Rodgers, Dante Pezzutti, Helen Duenas, Ryan Eaton, Daniel Kreatsoulas, J Bradley Elder, Daniel M Prevedello, Russell R Lonser, Shahid M Nimjee
OBJECTIVE: A growing body of literature suggests that preoperative opioid exposure is an independent predictor of poor outcomes in surgical patients. No outcomes data exist on preoperative opioid use and craniotomies/craniectomies. The objective of this study was to determine the impact of preoperative opioid use on 90-day adverse events after craniotomy or craniectomy. METHODS: A single-center retrospective cohort study of 2445 patients undergoing a craniotomy/craniectomy between January 1, 2013, and October 1, 2018, was conducted...
March 8, 2024: Journal of Neurosurgery