Xueqin Chen, Xiao Song, Hui Huang, Lian Zhang, Zhiqiang Song, Xichuan Yang, Shanchuan Lei, Zhifang Zhai
PURPOSE: Merkel cell carcinoma (MCC) is a rare neuroendocrine tumor of the skin, which mainly occurs in the sun exposed sites of white patients over 65 years, with a higher recurrence and metastasis rate. Clinically, MCC overlapping Bowen's disease (BD) is a very rare subtype of MCC. Few cases in the literature have been described and the management is not well defined. We summarize and update the epidemiology, clinical and histopathological features, metastasis characteristics, local recurrence rate and management of it by presenting two cases of MCC overlapping BD and reviewing the literature over the last 11 years...
April 26, 2024: Journal of Cancer Research and Clinical Oncology