Fredrick A Clive Wright, Sachiko Takehara, Fiona F Stanaway, Vasi Naganathan, Fiona M Blyth, Vasant Hirani, David G Le Couteur, David J Handelsman, Louise M Waite, Markus J Seibel, Robert G Cumming
OBJECTIVE: To investigate whether poorer oral health, tooth loss and lower usage of dental services are associated with depressive symptoms in older Australian men. METHODS: Cross-sectional study of data collected from participants of the Concord Health and Ageing in Men Project. Depressive symptoms were evaluated by the Geriatric Depression Scale. Chewing capacity was estimated by ability to chew 11 food items. RESULTS: The prevalence of depressive symptoms was 17...
January 13, 2020: Australasian Journal on Ageing
Ömer Faruk Boran, Bora Bilal, Nagihan Bilal, Hafize Öksüz, Maruf Boran, Fatih Mehmet Yazar
AIM: To compare the applicability, technical difficulties and postoperative complications of surgical tracheostomy and percutaneous dilatational tracheostomy with the flexible lightwand + ultrasonography method applied because of prolonged intubation to geriatric patients in the intensive care unit. METHODS: A retrospective evaluation was made of 76 patients who received surgical tracheostomy (group 1) and 78 patients who received percutaneous dilatational tracheostomy (group 2)...
January 14, 2020: Geriatrics & Gerontology International
Hisashi Kida, Shinichiro Nakajima, Ryo Shikimoto, Ryo Ochi, Yoshihiro Noda, Sakiko Tsugawa, Shinya Fujii, Midori Takayama, Masaru Mimura, Hidehito Niimura
AIM: Stress-related disorders and severe stress exposure can cause atrophy of the whole hippocampus and its subfields. However, the impact of stress coping strategies on the hippocampus remains unclear. Therefore, we aimed to examine the relationship between approach- and avoidance-oriented coping strategies and hippocampal volume in elderly persons. METHODS: A total of 1,045 elderly persons living in Arakawa-ward, Tokyo (mean ± standard deviation age: 72.8 ± 5...
January 13, 2020: Psychiatry and Clinical Neurosciences
Jared M Weiss, Nathan Pennell, Allison M Deal, Daniel Morgenzstern, Daniel S Bradford, Jeffrey Crane, Howard Jack West, Carrie Lee, Chad Pecot, James P Stevenson, William Irvin, Mark Socinski, Tom Stinchcombe, Liza C Villaruz, Hyman B Muss
BACKGROUND: The selection of later-line treatment for older patients with AJCC (version 7) stage IV non-small cell lung cancer (NSCLC) remains controversial. Nanoparticle albumin-bound (nab)-paclitaxel is approved with carboplatin for the first-line treatment of patients with NSCLC and subgroup analysis of phase 3 data has suggested superior survival in older patients. METHODS: The authors conducted a phase 2 study of nab-paclitaxel in 42 patients aged ≥70 years who had been treated previously with a platinum doublet regimen; patients also could have received a PD-1 inhibitor...
January 14, 2020: Cancer
Ali İhsan Uysal, Başak Altıparmak, Eylem Yaşar, Mustafa Turan, Umut Canbek, Nigar Yılmaz, Semra Gümüş Demirbilek
BACKGROUND: Hip fracture is a common clinical problem which causes severe pain in geriatric patients. However, severe pain following fracture may bring on mental disorders and delirium. A neuroinflammatory response with IL-6 and IL-8 has been shown to be associated with the pathophysiology of delirium. In this study, our primary hypothesis is that preoperative femoral nerve block (FNB) intervention in geriatric patients will more effectively attenuate pain following trochanteric femur fracture than the preoperative paracetamol application...
January 2020: Turkish Journal of Trauma & Emergency Surgery: TJTES
Ben Kirk, Ahmed Al Saedi, Gustavo Duque
Many older persons lose their mobility and independence due to multiple diseases occurring simultaneously. Geroscience is aimed at developing innovative approaches to better identify relationships among the biological processes of aging. Osteoporosis and sarcopenia are two of the most prevalent chronic diseases in older people, with both conditions sharing overlapping risk factors and pathogenesis. When occurring together, these diseases form a geriatric syndrome termed "osteosarcopenia," which increases the risk of frailty, hospitalizations, and death...
September 2019: Aging medicine
Dantao Peng
Cognitive impairment of cerebral small vessel disease (CSVD) is one of the most common cognitive disorders. It has a high incidence and results in heavy social burden; thus, it is essential to provide reasonable diagnosis and treatment in clinical practice. Based on the results of clinical research and related reports, combined with the actual situation in China, we propose a diagnosis and treatment guideline for cognitive impairment of CSVD.
June 2019: Aging medicine
Hee Jae Lee, MinJae Lee, Hyuntae Park, Jong Hwan Park, Kyung Won Park
Background and Purpose: The purpose of this study was to investigate the impact of multi-tasking exercise on cognitive and motor function in patients with mild cognitive impairment (MCI) and cognitive normal elderly (CNE). Methods: A total of 144 subjects were recruited from 14 regional dementia centers in Busan Metropolitan City. With the exception of 77 subjects unsuitable for the study, 67 subjects participated in the intervention. The Korean version of Mini-Mental State Examination for Dementia Screening (MMSE-DS), Subject Memory Complain Questionnaire (SMCQ), and the Korean version of the Short-Form Geriatric Depression Scale (SGDS-K) were used to determine changes in cognitive function and depressive symptoms pre-post intervention in patients with MCI and CNE, respectively...
December 2019: Dementia and neurocognitive disorders
Anshu Mittal, Anisha Aggarwal, Shefali Nayyar, Ankita Thakral, Harsimranjit Kaur Natt, Arundeep Singh
Context: Aging is a natural process which universally affects all the human beings in the society. As the geriatric population is quiet vulnerable, They might suffer from mental and physical disabilities which consequently threatens their independence. Quality of life among the geriatric population is a global concern as it reflects the status of health and of well being among the set population. Aims: To assess the quality of life of elderly living in rural and urban areas and compare the role of socio-demographic factors influencing the quality of life of elderly...
October 2019: Journal of Mid-life Health
J Abendroth, A Klement
The increasing proportion of older and polymorbid people in the population also means an increase in polymedication and its risks. This places new and complex demands on the interdisciplinary and transsectoral collaboration. The preoperative, perioperative and postoperative management of polymedication is described in the article with respect to frequent risks and the chances of a systematic exchange of information. The establishment of an interdisciplinary admission routine in departments of surgery and communication with the family practitioner is crucial for patient safety...
January 15, 2020: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
Yangyang Zhou, Yunfeng Rui, Panpan Lu, Xiaodong Qiu, Jihong Zou, Xingjuan Li, Liqun Ren, Songqiao Liu, Yi Yang, Ming Ma, Chen Wang, Hui Chen
Objective: To summarize the research progress of multidisciplinary team (MDT) co-management models in the clinical treatment of geriatric hip fractures. Methods: The literature about types and characteristics of MDT for geriatric hip fracture treatment were extensively reviewed, and the advantages of its clinical application were analysed and summarised. Finally, the MDT model and characteristics of geriatric hip fracture in the Zhongda Hospital affiliated to Southeast University were introduced in detail...
January 15, 2020: Chinese Journal of Reparative and Reconstructive Surgery
F Ghignone, P Hernandez, N N Mahmoud, G Ugolini
Colorectal cancer is a widely-recognized aging-associated disease. Recent advances in the care of senior colorectal cancer patients has led to similar cancer-related life expectancy for older patients when compared to their younger counterparts. Recent data suggests that onco-geriatric patients place as much value on maintenance of functional independence and quality of life after treatment as they do on the potential improvements in survival that a treatment might offer. As a result, there has been significant interest in the geriatric literature surrounding the concept of "functional recovery," a multidimensional outcome metric that takes into account several domains, including physical, physiologic, psychological, social, and economic wellbeing...
January 8, 2020: European Journal of Surgical Oncology
Barbara Barros Silva, Claudia Fegadolli
BACKGROUND: Pharmaceutical care services have been recognized as the most highly regarded professional pharmacy practice model that allows the identification, intervention, and resolution of drug related problems. This practice provides significant clinical outcomes and can reduce direct and indirect costs for health systems. However, its implementation can be complex and challenging, needing study experiences that aims at overcoming obstacles, especially in free and universal healthcare systems...
January 14, 2020: BMC Health Services Research
César Gálvez-Barrón, Francesc Formiga, Antonio Miñarro, Oscar Macho, Leire Narvaiza, María Dolores Dapena, Ramon Pujol, Alejandro Rodríguez-Molinero
BACKGROUND: Recurrent falls represent a priority in geriatric research. In this study we evaluated the influence of pain as a risk factor for recurrent falls (two or more in 1 year) in the older (65-79 years) and oldest-old (80 or more years) non-institutionalized population. METHODS: Prospective cohort study. 772 non-institutionalized individuals with ages of 65 years or older (with overrepresentation of people aged 80 years or older [n = 550]) were included through randomized and multistage sampling, stratified according to gender, geographic area and habitat size...
January 14, 2020: BMC Geriatrics
Y M Wang, W C Duan, W W Wang, Y P Zhao, X Z Liu, Z Y Zhang
Objective: This study was designed to investigate prognostic factors and the potential relationship between the expression of Ki67 and IDH of glioblastoma in the elderly (≥ 65 years old) and the clinical factors such as gender, the KPS score and treatments including surgical resection, radiotherapy and chemotherapy and the prognosis of such patients. Methods: Fifty-four elderly patients (≥ 65 years old) with glioblastoma admitted to the First Affiliated Hospital of Zhengzhou University from 2013 to 2018 were enrolled in this study...
January 14, 2020: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Åsa Karlsson, Nina Lindelöf, Birgitta Olofsson, Monica Berggren, Yngve Gustafson, Peter Nordström, Michael Stenvall
OBJECTIVE: To evaluate the effects of early discharge followed by geriatric interdisciplinary home rehabilitation for older people with hip fracture on independence in Activities of Daily Living (ADLs) compared with in-hospital geriatric care according to a multifactorial rehabilitation program. DESIGN: Pre-planned analysis of a randomized controlled trial with 3 and 12 month follow-ups. SETTING: Geriatric ward, ordinary housing and residential care facilities...
January 11, 2020: Archives of Physical Medicine and Rehabilitation
Ahuva Even-Zohar, Shoshi Werner
The study examined the effect of an educational intervention on the willingness of Israeli social work students to work with older adults, comparing them to students of nursing, speech therapy, and physiotherapy. A sample of 187 first-year students were divided into two groups: a research group (n=83) exposed to an educational intervention on ageing, and a control group (n=104) that received no intervention of any kind. Following the intervention, ageism among social work students in the research group decreased and positive behavior toward older adults increased...
January 14, 2020: Journal of Gerontological Social Work
Chun-Li Zhang, Ru Feng, Jiang-Tao Li, Ting Wang, Jie-Fei Bai, Hui Liu
BACKGROUND: Acute myeloid leukemia (AML) is a common type of hematological malignancy in elderly people. Geriatricians have developed comprehensive geriatric assessment (CGA) methods for elderly patients; however, the tools used for CGA in AML are not uniform. Thus, we aimed to validate the instrumental activities of daily living (IADL) scales, age, comorbidities (Charlson Comorbidity Index), and albumin (IACA) index, which is a new tool for CGA, in elderly patients with AML. METHODS: Patients aged ≥60 years who had been diagnosed with AML were screened for eligibility...
January 13, 2020: Chinese Medical Journal
Comfort Kunak Ogar, Abiodun Abiola, Daniel Yuah, Ali Ibrahim, Ibrahim Adekunle Oreagba, Emmanuel C Amadi, Mojisola Christianah Adeyeye, Kazeem Adeola Oshikoya
BACKGROUND: Adverse drug reactions (ADRs) are a source of concern in healthcare as they negatively affect patients. Serious adverse drug reactions (SADRs) have an even greater impact on patients and the system in terms of morbidity and financial burden. The establishment of National Pharmacovigilance Centers (NPCs) has enhanced ADR reporting in Africa. The Nigerian Pharmacovigilance Centre has been collecting ADR reports using VigiFlow since 2004. OBJECTIVE: The aim of this study was to identify and analyze SADR reports in the Nigerian VigiFlow database in order to profile the patients with SADRs, the medicines most implicated, system organ classes (SOCs) affected, outcome of such reactions, including fatalities, and ADR reporting trends over the years...
April 2019: Pharmaceutical Medicine
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