Gui-Ming Fu, Zhao-Hui Wang, Yi-Bo Chen, Chun-Hua Li, Yue-Jia Zhang, Xiao-Jing Li, Quan-Xin Wan
Background: With guidance from the American Joint Committee on Cancer (AJCC) Cancer Staging Manual, 8th edition, we explored the characteristics of central lymph node metastasis (CLNM) of papillary thyroid micro-carcinoma (PTMC) in elderly patients ≥55 years of age. Our goal was to provide references for establishing a lymph node dissection scheme in such patients. Methods: We retrospectively analyzed the clinical data of thyroid cancer patients admitted to the Head and Neck Surgery Center of Sichuan Cancer Hospital, Chengdu, China, from January 2015 to September 2018...
2020: Cancer Management and Research
Mingbo Zhang, Ralph P Tufano, Jonathon Russell, Ying Zhang, Yan Zhang, Zhi Qiao, Yukun Luo
BACKGROUND: Papillary thyroid micro-carcinoma (PTMC) typically carries an excellent prognosis regardless of the treatment option pursued. Radiofrequency ablation (RFA) for thyroid disease has been utilized for benign lesions and in patients who are poor surgical candidates for thyroid cancers with compression symptoms, but the efficacy and limitations of RFA as first line therapy for PTMC has not been described in adequate detail. The purpose of our study was to investigate RFA versus thyroidectomy in terms of efficacy, oncologic outcomes, quality of life, complications and costs over a five year period of follow-up...
January 7, 2020: Thyroid: Official Journal of the American Thyroid Association
Dana Stoian, Florin Borcan, Izabella Petre, Ioana Mozos, Flore Varcus, Viviana Ivan, Andreea Cioca, Adrian Apostol, Cristina Adriana Dehelean
Fine needle aspiration (FNA) is considered the gold standard in the diagnostic of thyroid nodules. Using the recommended BETHESDA reporting system, up to 20% of results are classified as intermediate cytology. As there is no consensus whether ultrasound evaluation, lobectomy or surgery is the best treatment option, intermediate cytology results are considered a grey zone of the FNA. The main aim of our study was to evaluate the performance of combined advanced ultrasound techniques in the process of diagnosis and evaluation of the intermediate cytology cases after FNA...
September 13, 2019: Diagnostics
Maud Charvin, Hans Martin Späth, Alain Bernard, Anne-Claire Bertaux
Background: Two surgical strategies called video-assisted thoracoscopy surgery (VATS) and thoracotomy are used for lobectomy following lung cancer diagnosis. The aim of this study was to assess the total cost of each technique (thoracotomy and VATS) during hospitalization in France. Methods: A micro-costing methodology from the hospital perspective was implemented to assess the hospitalization costs, using direct observations, interviews, and data collection based on medical records in four hospitals...
April 2019: Journal of Thoracic Disease
Hasan Calis, Nuraydin Ozlem, Serif Melih Karabeyoglu
Coincidence of primary hyperparathyroidism and thyroid nodules is quite frequent. This is challenging for clinical diagnosis and treatment. We reviewed the records of patients who underwent surgery for primary hyperparathyroidism. Among 52 such cases, thyroidectomy was performed in seven patients (13%) at the same time. Papillary thyroid cancer was detected in five patients (9.6%) as a result of pathologic examination. Two patients were diagnosed with unifocal micro-papillary cancer and these patients underwent unilateral thyroid lobectomy...
June 2019: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Liping Tong, Xiaoqing Zheng, Hongtao Duan, Honggang Liu, Xiaofei Li, Xiaolong Yan
Background: Conventional three-port video-assisted thoracic surgery (VATS) is well established internationally. Meanwhile, uniportal VATS technique has been become more and more popular in the past two decades. However, both methods have their merits and drawbacks. The purpose of this paper is to compare the surgical outcome of patients with lung cancer between traditional three-port VATS and our new two micro-portal VATS technique in an attempt to validate the safety, feasibility and efficacy of the latter procedure...
October 2018: Journal of Thoracic Disease
Yunjun Wang, Qing Guan, Jun Xiang
INTRODUCTION: The status of central lymph node metastasis (CLNM) is crucial to determining the surgical strategies for papillary thyroid micro carcinoma (PTMC). The objective of the study was to establish a nomogram to predict the possibility of CLNM in PTMC patients. METHODS: A total of 8668 PTMC patients who underwent total thyroidectomy or lobectomy with central lymph node dissection (CLND) from 2006 to 2016 were retrospectively retrieved. Univariate and multivariate analysis were performed to examine risk factors associated with CLNM...
July 2018: International Journal of Surgery
Shaohua Ma, Tiansheng Yan, Keyi Wang, Jingdi Wang, Jintao Song, Tong Wang, Wei He, Jie Bai, Liang Jin, Hailong Liang
BACKGROUND: Segmentectomy can retains more healthy lung tissue than lobectomy, but it remains controversial in oncology for early stage lung cancer. The aim of this study is to discuss the problems of video-assisted thoracic surgery (VATS) segmentectomy in early stage lung cancer, by analyzing the clinical and pathological data of 35 cases and reviewing the literature. METHODS: There were 35 patients who received segmentectomy by complete video-assisted thoracic surgery, from May 2013 to July 2017, in single operation group in the Third Hospital of Peking University...
February 20, 2018: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Amit Ritter, Gideon Bachar, Dania Hirsch, Carlos Benbassat, Orna Katz, Nadav Kochen, Talia Diker-Cohen, Amit Akirov, Ilan Shimon, Eyal Robenshtok
Background: Bilateral thyroid nodularity is considered an indication for total thyroidectomy in papillary thyroid carcinoma (PTC). However, the natural history and outcome of contralateral nodules have never been studied. Objective: To investigate the natural history of nonsuspicious contralateral nodules after lobectomy for PTC. Methods: We included patients who had one or more solid nodules (≥3 mm) in the contralateral lobe with benign cytology before surgery or small nonsuspicious nodules per ultrasonography...
February 1, 2018: Journal of Clinical Endocrinology and Metabolism
Darshan P Trivedi, Ramesh Bhagat, Yukihiro Nakanishi, Alun Wang, Krzysztof Moroz, Nadja K Falk
BACKGROUND: Granulomatous disease in the thyroid gland has been linked to viral, bacterial and autoimmune etiologies. The most common granulomatous disease of the thyroid is subacute granulomatous thyroiditis, which is presumed to have a viral or post-viral inflammatory cause. Bacterial etiologies include tuberculosis, actinomycosis, and nocardiosis, but are extremely rare. Disseminated actinomycosis and nocardiosis more commonly affect organ-transplant patients with the highest susceptibility within the first year after transplant surgery...
September 2017: Annals of Clinical and Laboratory Science
T Bansal, S Kiran, K Kamal, N Bangarwa
Bronchogenic cyst, a benign congenital cystic lesion of the lung, is a rare cause of respiratory distress in children comprising 7.5% of all mediastinal masses. A thorough preoperative evaluation is crucial to plan for definitive intra- and post-operative management. All patients should be thoroughly evaluated for the presence of compression, deviation or distortion of airways and great veins. The easiest means of providing one lung ventilation in pediatrics is to intubate the main stem bronchus of the nonoperated lung...
July 2017: Saudi Journal of Anaesthesia
Tong Wang, Tiansheng Yan, Feng Wan, Shaohua Ma, Keyi Wang, Jingdi Wang, Jintao Song, Wei He, Jie Bai, Liang Jin
BACKGROUND: The development of image technology has led to increasing detection of pulmonary small nodules year by year, but the determination of their nature before operation is difficult. This clinical study aimed to investigate the necessity and feasibility of surgical resection of pulmonary small nodules through a minimally invasive approach and the operational manner of non-small cell lung cancer (NSCLC). METHODS: The clinical data of 129 cases with pulmonary small nodule of 10 mm or less in diameter were retrospectively analyzed in our hospital from December 2013 to November 2016...
January 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Taiji Kuwata, Kazue Yoneda, Kenichi Kobayashi, Rintarou Oyama, Hiroki Matumiya, Shuichi Shinohara, Masaru Takenaka, Soichi Oka, Yasuhiro Chikaishi, Naoko Inanishi, Koji Kuroda, Fumihiro Tanaka
BACKGROUND Circulating tumor cells (CTCs) are tumor cells that are shed from primary tumors and circulate in the peripheral blood. CTCs, as a surrogate of micro-metastasis, can be a useful clinical marker, but their clinical significance remains unclear in lung cancer. We now report a case of lung cancer in which the count of CTCs was useful in monitoring postoperative recurrence. CASE REPORT A 50-year-old man had undergone right upper lobectomy for lung cancer (pT1bN2M0, stage IIIA adenocarcinoma), followed by cisplatin-based adjuvant chemotherapy...
September 15, 2016: American Journal of Case Reports
Paolo Del Rio, Chiara Montana Montana, Giulia Mingardi, Giovanna Piva, Mario Sianesi, Luigi Corcione
BACKGROUND: The incidence of thyroid carcinoma ranges from 0.5 to 10 cases every 100,000, depending on the country, the context and purpose of the study. The high incidence of differentiated thyroid tumor is continuously growing. While most malignant pathologies affect the adults, a proportion of 1-2% of pediatric population is affected by solitary nodule, of which some are malignant cancers. Studying thyroid malignant cancer, the most sensitive and accurate imaging technique is color Doppler ultrasonography...
September 2017: Minerva Endocrinologica
S Périé, F Torti, M Lefevre, N Chabbert-Buffet, A Jafari, J Lacau St Guily
OBJECTIVES: To quantify and discuss the prevalence of unsuspected thyroid lymph node metastases discovered in specimens from neck dissection for head and neck squamous cell carcinoma (HNSCC) and discuss the impact on patient management. STUDY DESIGN: Retrospective study between May 2004 and January 2007. SETTING: University hospital. METHODS: Pathological analysis of cervical lymph node dissection performed during surgery for HNSCC in a total of 349 neck dissections in 266 consecutive patients...
December 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
Shi Yan, Xing Wang, Chao Lv, Kevin Phan, Yuzhao Wang, Jia Wang, Yue Yang, Nan Wu
BACKGROUND: Postoperative pleural drainage markedly influences the length of postoperative stay and financial costs of medical care. The aim of this study is to retrospectively investigate potentially predisposing factors related to pleural drainage after curative thoracic surgery and to explore the impact of mediastinal micro-vessels clipping on pleural drainage control after lymph node dissection. METHODS: From February 2012 to November 2013, 322 consecutive cases of operable non-small cell lung cancers (NSCLC) undergoing lobectomy and mediastinal lymph node dissection with or without application of clipping were collected...
March 2016: Journal of Thoracic Disease
Ying Zhou, Yunyuan Li, Li Fan, Shiyuan Liu
During a thoracic computed tomography (CT) scan, a 36-year-old male was diagnosed with a solitary oval pulmonary mixed ground-glass nodule in the right upper lobe of the lung. The edge of the nodule was well-defined, and its largest axial size was approximately 1.1 × 0.9 cm(2). This nodule was slightly lobulated, but not obviously speculated. Solid components, micro-cystic lucency shadow, small high-density rings and tiny vascular branches were all visible in the nodule. During hospitalization, a technetium 99 m methylene diphosphonate (Tc-99 m MDP) bone scan was performed, which showed a skeletal foci with abnormal uptake in the left iliac...
2015: International Journal of Clinical and Experimental Pathology
Jinbai Miao, Shengcai Hou, Xiaoxing Hu, Tong Li, Bin Hu, Hui Li
OBJECTIVE: To investigate the relationship of the preoperative HRCT, postoperative pathological subtype and EGFR gene mutation types in the patients of small peripheral lung adenocacinoma confirmed by operation. METHODS: Between December 2011 and November 2014, Ninety-four invasive adenocarcinoma patient were selected from 156 patients with pulmonary nodule underwent operation in Beijing Chaoyang hospital. Among them, there were male 37 cases, female 57 cases, age range from 32 to 76, mean age 52...
September 1, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Pinar Yazici, Mehmet Mihmanli, Emre Bozdag, Nurcihan Aygun, Mehmet Uludag
OBJECTIVE: The relationship between primary hyperparathyroidism (pHPT) and papillary thyroid cancer (PTC) still remains unclear. We aimed to investigate the incidence of the co-existence of pHPT and PTC. MATERIALS AND METHODS: Between 2010 and 2013, all patients with pHPT were retrospectively reviewed and those undergoing concomitant thyroid surgery were recorded. Of these, patients with a pathological result showing papillary or micro-papillary thyroid cancer were included into the study...
October 2015: Eurasian Journal of Medicine
G Donatini, M Castagnet, T Desurmont, N Rudolph, D Othman, J L Kraimps
BACKGROUND: Total thyroidectomy is a well-established surgical approach for the management of papillary thyroid cancer (PTC). However, the best surgical approach for papillary microcarcinoma is nowadays still debated. Both total thyroidectomy and simple lobectomy are used. We report the experience of a single University center in the treatment of thyroid microcarcinoma. METHODS: A retrospective analysis on all patients who underwent thyroid surgery at our institution over a 24-year period (1991-2015) was performed...
March 2016: World Journal of Surgery
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