Hassan Hussain Almasoudi, Mutaib M Mashraqi, Saleh A Alshamrani, Afaf Awwadh Alharthi, Ohud Alsalmi, Mohammed H Nahari, Fares Saeed H Al-Mansour, Abdulfattah Yahya M Alhazmi
Breast cancer begins in the breast cells, mainly impacting women. It starts in the cells that line the milk ducts or lobules responsible for producing milk and can spread to nearby tissues and other body parts. In 2020, around 2.3 million women across the globe received a diagnosis, with an estimated 685,000 deaths. Additionally, 7.8 million women were living with breast cancer, making it the fifth leading cause of cancer-related deaths among women. The mutational changes, overexpression of drug efflux pumps, activation of alternative signalling pathways, tumour microenvironment, and cancer stem cells are causing higher levels of drug resistance, and one of the major solutions is to identify multitargeted drugs...
February 6, 2024: Pharmaceuticals