keyword
https://read.qxmd.com/read/38629017/irregular-tremulous-movements-and-infrequent-seizures-a-clinical-electrophysiological-diagnosis-of-benign-adult-familial-myoclonus-epilepsy
#41
Kazuki Imon, Shuichiro Neshige, Akiko Maeda, Yumiko Yamamoto, Hirofumi Maruyama
We report a case involving a 31-year-old male without any known precipitating injuries presenting with involuntary finger movements and rare seizures. There was a noted family history of tremulous movements. Yet the characteristics of his finger movements were irregular and not typical of essential tremor (ET). Electrophysiological examinations, including video EEG, showed no epileptic discharges, and brain MRI results were normal. However, somatosensory evoked potentials (SEP) revealed the presence of giant SEP, and a positive cortical (C)-reflex was observed, leading to a clinical diagnosis of benign adult familial myoclonus epilepsy (BAFME)...
March 2024: Curēus
https://read.qxmd.com/read/38626375/association-of-localizing-18-f-fdg-pet-hypometabolism-and-outcome-following-epilepsy-surgery-systematic-review-and-meta-analysis
#42
JOURNAL ARTICLE
Merran R Courtney, Ana Antonic-Baker, Zhibin Chen, Benjamin Sinclair, John-Paul Nicolo, Andrew Neal, Cassandra Marotta, Jacob Bunyamin, Meng Law, Patrick Kwan, Terence J O'Brien, Lucy Vivash
BACKGROUND AND OBJECTIVES: Although commonly used in the evaluation of patients for epilepsy surgery, the association between the detection of localizing 18 fluorine fluorodeoxyglucose PET (18 F-FDG-PET) hypometabolism and epilepsy surgery outcome is uncertain. We conducted a systematic review and meta-analysis to determine whether localizing 18 F-FDG-PET hypometabolism is associated with favorable outcome after epilepsy surgery. METHODS: A systematic literature search was undertaken...
May 14, 2024: Neurology
https://read.qxmd.com/read/38615072/open-access-eeg-dataset-of-repeated-measurements-from-a-single-subject-for-microstate-analysis
#43
JOURNAL ARTICLE
Qi Liu, Shuyong Jia, Na Tu, Tianyi Zhao, Qiuyue Lyu, Yuhan Liu, Xiaojing Song, Shuyou Wang, Weibo Zhang, Feng Xiong, Hecheng Zhang, Yi Guo, Guangjun Wang
Electroencephalography (EEG) microstate analysis is a neuroimaging analytical method that has received considerable attention in recent years and is widely used for analysing EEG signals. EEG is easily influenced by internal and external factors, which can affect the repeatability and stability of EEG microstate analysis. However, there have been few reports and publicly available datasets on the repeatability of EEG microstate analysis. In the current study, a 39-year-old healthy male underwent a total of 60 simultaneous electroencephalography and electrocardiogram measurements over a period of three months...
April 13, 2024: Scientific Data
https://read.qxmd.com/read/38610005/subclinical-epileptiform-discharges-in-alzheimer-s-disease-are-associated-with-increased-hippocampal-blood-flow
#44
JOURNAL ARTICLE
Christian Sandøe Musaeus, Troels Wesenberg Kjaer, Ulrich Lindberg, Mark B Vestergaard, Henrik Bo, Wiberg Larsson, Daniel Zvi Press, Birgitte Bo Andersen, Peter Høgh, Preben Kidmose, Martin Christian Hemmsen, Mike Lind Rank, Steen Gregers Hasselbalch, Gunhild Waldemar, Kristian Steen Frederiksen
BACKGROUND: In epilepsy, the ictal phase leads to cerebral hyperperfusion while hypoperfusion is present in the interictal phases. Patients with Alzheimer's disease (AD) have an increased prevalence of epileptiform discharges and a study using intracranial electrodes have shown that these are very frequent in the hippocampus. However, it is not known whether there is an association between hippocampal hyperexcitability and regional cerebral blood flow (rCBF). The objective of the study was to investigate the association between rCBF in hippocampus and epileptiform discharges as measured with ear-EEG in patients with Alzheimer's disease...
April 12, 2024: Alzheimer's Research & Therapy
https://read.qxmd.com/read/38608404/the-infant-gut-microbiome-and-cognitive-development-in-malnutrition
#45
REVIEW
Inoli Shennon, Brooke C Wilson, Anna H Behling, Theo Portlock, Rashidul Haque, Terrence Forrester, Charles A Nelson, Justin M O'Sullivan
Malnutrition affects 195 million children under the age of five worldwide with long term effects that include impaired cognitive development. Brain development occurs rapidly over the first 36 months of life. Whilst seemingly independent, changes to the brain and gut microbiome are linked by metabolites, hormones, and neurotransmitters as part of the gut-brain axis. In the context of severe malnutrition, the composition of the gut microbiome and the repertoire of biochemicals exchanged via the gut-brain axis vary when compared to healthy individuals...
April 4, 2024: Clinical Nutrition
https://read.qxmd.com/read/38603939/applicability-of-the-international-league-against-epilepsy-ilae-2022-diagnostic-criteria-for-epilepsy-syndromes-in-children-a-retrospective-review-of-1550-children-with-epilepsy
#46
JOURNAL ARTICLE
Bhavya Kansal, Aakanksha Anand, Divyani Garg, Anshika Gupta, Ashna Kumar, Suvasini Sharma
OBJECTIVE: Recently, the ILAE Nosology and Definitions Task Force defined diagnostic criteria for epilepsy syndromes. There is paucity of data on the use of these new diagnostic criteria in children with epilepsy, and how these criteria may lead to changes from previous practice. METHODS: This was a retrospective chart review of data of children attending the epilepsy clinic in a tertiary care children's hospital from January 2011 to January 2023. The clinical details such as age at onset, types of seizures, co-morbidities, and results of EEG, MRI and genetic testing were reviewed...
March 27, 2024: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/38600450/adult-vasovagal-syncope-with-abdominal-pain-diagnosed-by-head-up-tilt-combined-with-transcranial-doppler-a-preliminary-study
#47
JOURNAL ARTICLE
Jingyi Wang, Hua Li, Xuming Huang, Huoyou Hu, Baorong Lian, Daxue Zhang, Jiarui Wu, Liming Cao
BACKGROUND: Syncope is a common condition that increases the risk of injury and reduces the quality of life. Abdominal pain as a precursor to vasovagal syncope (VVS) in adults is rarely reported and is often misdiagnosed.​. METHODS: We present three adult patients with VVS and presyncopal abdominal pain diagnosed by synchronous multimodal detection (transcranial Doppler [TCD] with head-up tilt [HUT]) and discuss the relevant literature. RESULTS: Case 1: A 52-year-old man presented with recurrent decreased consciousness preceded by six months of abdominal pain...
April 10, 2024: BMC Neurology
https://read.qxmd.com/read/38599500/association-of-rheumatological-markers-with-neuronal-antibodies-cerebrospinal-fluid-electroencephalography-and-magnetic-resonance-imaging-findings-in-224-patients-with-psychotic-syndromes
#48
JOURNAL ARTICLE
Dominique Endres, Katharina von Zedtwitz, Kathrin Nickel, Kimon Runge, Alexander Maier, Katharina Domschke, Ulrich Salzer, Harald Prüss, Nils Venhoff, Ludger Tebartz van Elst
INTRODUCTION: Psychotic syndromes can have autoimmune-mediated causes in some patients. Thus, this retrospective work aims to investigate the role of rheumatological markers in the development of psychosis. PATIENTS AND METHODS: In total, 224 patients with psychotic syndromes receiving a "rheumatological laboratory screening" (including C-reactive protein [CRP], immunofixation, complement factors, rheumatoid factor [RF], antiphospholipid antibodies [APAs], antineutrophil cytoplasmic antibodies [ANCAs], and antinuclear antibodies [ANAs]) were analyzed...
April 8, 2024: Brain, Behavior, and Immunity
https://read.qxmd.com/read/38598313/the-varied-clinical-and-radiological-manifestations-of-contrast-induced-encephalopathy-following-coronary-angiography
#49
JOURNAL ARTICLE
J Willman, J O Ruuskanen, M Hassan, J M Mustonen, J Leppänen, Mny Lähteenoja, Jot Sipilä
Contrast-induced encephalopathy (CIE) is a rare complication of imaging using ionidated contrast media. Its pathogenesis remains unknown, and its clinical presentation is variable. We present two cases of CIE following coronary angiography (CAG) that underscore the multitude of clinical manifestations and imaging findings associated with the disorder. In patients 1, CIE manifested during the CAG with agitation and decreased consciousness, followed by left hemiparesis and visual neglect. Native computed tomography (CT) of the head was unremarkable but CT perfusion (CTP) showed extensive hypoperfusion of the right hemisphere with corresponding slow-wave activity in the electroencephalogram (EEG)...
April 10, 2024: International Journal of Neuroscience
https://read.qxmd.com/read/38595968/editorial-translational-applications-of-neuroimaging
#50
EDITORIAL
Amelie Haugg, David M A Mehler, Stavros Skouras
No abstract text is available yet for this article.
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38595635/cns-demyelination-syndromes-following-covid-19-vaccination-a-case-series
#51
Yasser Hamed, Abd-Elaziz Shokry, Khaled Mohamed Ali Shehata, Salma Mokhtar Osman, Khaled Saad, Safwat Salama Sawy, Emad Abdelrazzak, Omran Mohamed Abdelmola, Tarek Mansour
BACKGROUND AND OBJECTIVES: Although immunization against coronavirus disease 2019 (COVID-19) is ongoing, adverse reactions to these vaccinations have been observed in isolated cases. We aimed to report different neurological complications developed after COVID-19 vaccination. MATERIALS AND METHODS: In our case series study, we report all cases of CNS demyelination following COVID-19 immunization. Clinical evaluation, brain MRI, and CSF analysis for oligoclonal bands and IgG index were performed for all patients...
February 2024: Journal of Pharmacy & Bioallied Sciences
https://read.qxmd.com/read/38592219/visual-snow-syndrome-in-patient-with-migraine-case-report-and-literature-review
#52
REVIEW
Justyna Chojdak-Łukasiewicz, Edyta Dziadkowiak
Visual snow syndrome (VSS) is a rarely diagnosed neurological phenomenon. It is a visual disorder characterised by the presence of numerous white, black, or translucent dots in the visual field, resembling the 'snow' of an analogue TV set experiencing reception interference. According to The International Classification of Headache Disorders, 3rd edition, visual snow is defined as a pattern of continuous small dots across the visual field lasting >3 months and accompanied by at least two of the following four additional symptoms: palinopsia, increased entoptic phenomena, photophobia, and nyctalopia...
February 28, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38590926/subarachnoid-hemorrhage-confirmed-by-magnetic-resonance-imaging-in-a-patient-with-brain-death-owing-to-hypoxic-encephalopathy-following-suicide-by-hanging
#53
Sotaro Oshida, Tomoki Yokosawa, Shizuka Araya, Shinpei Sato, Taro Suzuki, Yosuke Akamatsu, Kuniaki Ogasawara
Although true subarachnoid hemorrhage (SAH) is an atypical complication owing to suicide by hanging, pseudo-SAH can often develop because of hypoxic encephalopathy. Therefore, differentiating pseudo-SAH from true SAH using brain computed tomography (CT) is often challenging. In Japan, an individual's cause of brain death must be determined to be eligible for organ donation, regardless of whether true SAH is involved or not. Herein, we report a case of SAH confirmed by magnetic resonance imaging (MRI) in a patient with brain death owing to hypoxic encephalopathy following suicide by hanging...
2024: NMC Case Report Journal
https://read.qxmd.com/read/38580035/structural-or-and-functional-mri-based-machine-learning-techniques-for-attention-deficit-hyperactivity-disorder-diagnosis-a-systematic-review-and-meta-analysis
#54
REVIEW
Lu Tian, Helin Zheng, Ke Zhang, Jiawen Qiu, Xuejuan Song, Siwei Li, Zhao Zeng, Baosheng Ran, Xin Deng, Jinhua Cai
BACKGROUND: The aim of this study was to investigate the diagnostic value of ML techniques based on sMRI or/and fMRI for ADHD. METHODS: We conducted a comprehensive search (from database creation date to March 2024) for relevant English articles on sMRI or/and fMRI-based ML techniques for diagnosing ADHD. The pooled sensitivity, specificity, positive likelihood ratio (LR+), negative likelihood ratio (LR-), summary receiver operating characteristic (SROC) curve and area under the curve (AUC) were calculated to assess the diagnostic value of sMRI or/and fMRI-based ML techniques...
April 3, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38576698/hereditary-creutzfeldt-jakob-disease-a-case-presentation-of-a-rare-stroke-mimic
#55
Rachel E Bridwell, Jessica A Barlow, Andrew R Jacobson, Angela Curell, Brit Long
Acute ischemic cerebrovascular accident (CVA) is a time-sensitive emergent diagnosis, requiring rapid diagnosis and consideration of thrombolytic administration. However, a myriad of cerebrovascular mimics creates a diagnostic challenge. A rare CVA mimic is Creutzfeldt-Jakob disease (CJD), a rapidly progressive fatal dementia due to protein misfolding. Magnetic resonance imaging (MRI) and neurology consultation for electroencephalogram (EEG) and specialized cerebrospinal fluid (CSF) studies are diagnostic while the patient is alive...
March 2024: Curēus
https://read.qxmd.com/read/38576530/autosomal-recessive-primary-microcephaly-type-2-associated-with-a-novel-wdr62-splicing-variant-that-disrupts-the-expression-of-the-functional-transcript
#56
JOURNAL ARTICLE
Haizhu Chen, Ying Zheng, Hua Wu, Naiqing Cai, Guorong Xu, Yi Lin, Jin-Jing Li
BACKGROUND: Autosomal recessive primary microcephaly (MCPH) is a rare neurodevelopmental disorder characterized primarily by congenital microcephaly and intellectual disability but without extra-central nervous system malformations. This investigation aimed to elucidate the genetic underpinnings of microcephaly in a patient from a Chinese consanguineous family. METHODS: A comprehensive clinical assessment, including brain magnetic resonance imaging (MRI), electroencephalogram (EEG), and genetic analyses, was conducted to evaluate the patient's condition...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38572492/iglon5-autoimmunity-in-a-patient-with-creutzfeldt-jakob-disease-case-report-and-review-of-literature
#57
Xiaofeng Li, Yimin Chen, Le Zhang, Wei Zhang, Bin Li, José Fidel Baizabal-Carvallo, Xingwang Song
OBJECTIVE: We present the case of a patient with clinical and imaging features of sporadic Creutzfeldt-Jakob disease (sCJD) and positive IgLON5 antibodies (Abs) in the serum and CSF. CASE REPORT: A 66-year-old Chinese man presented to the hospital with a stroke-like episode, followed by rapidly progressive cognitive decline, mutism, and parkinsonism. The MRI results showed a cortical ribboning sign in diffusion-weighted MRI, periodic triphasic waves with a slow background in EEG, and positive protein 14-3-3 in CSF...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38569383/tnf-%C3%AE-a-serological-marker-for-evaluating-the-severity-of-hippocampal-sclerosis-in-medial-temporal-lobe-epilepsy
#58
JOURNAL ARTICLE
Bingbing Wang, Qingyun Li, Heng Wang, Xin Du, Qingwei Lai, Xinyu Li, Yinan Wang, Peng Hu, Hongbin Fan
OBJECTIVE: By analysing the difference in TNF-α levels in the peripheral blood of patients with medial temporal lobe epilepsy (mTLE) with or without hippocampal sclerosis and the correlation between TNF-α and N-acetylaspartate levels in the hippocampus, we explored the relationship between TNF-α and the degree of damage to hippocampal sclerosis neurons in medial temporal lobe epilepsy. METHODS: This is a prospective, population-based study. A total of 71 Patients with medial temporal lobe epilepsy diagnosed by clinical seizures, video-EEG, epileptic sequence MRI, and other imaging examinations were recruited from October 2020 to July 2022 in the Department of Neurology, Affiliated Hospital of Xuzhou Medical University...
April 2, 2024: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://read.qxmd.com/read/38565197/three-patients-of-the-early-onset-epileptic-spasms-without-hypsarrhythmia
#59
JOURNAL ARTICLE
Ikko Ohshiro, Tohru Okanishi, Ryo Ohta, Kento Ohta, Yuto Arai, Sotaro Kanai, Ayataka Fujimoto, Yoshihiro Maegaki
Epileptic spasms without hypsarrhythmia occur when patients do not display hypsarrhythmia on electroencephalogram (EEG) at the onset and throughout the clinical course. We report three patients of epileptic spasms in patients with early onset, all of whom experienced other types of seizures.We detail three patients (two boys and one girl) of epileptic spasms without hypsarrhythmia, occurring between 1 and 3 months of age, with no abnormalities detected on neurometabolic analysis and brain magnetic resonance imaging...
April 24, 2024: Neuropediatrics
https://read.qxmd.com/read/38564992/sensory-ataxic-polyneuropathy-unmasking-late-onset-urea-cycle-defect
#60
Ravi Krishna Kanth, Naman Agrawal, Pratik Patel, Anka Arora, Manish Chaturvedy, Sarbesh Tiwari, Divya Aggarwal, Samhita Panda
A 63-year-old man with type 2 diabetes mellitus, alcohol consumption in moderation, and three episodes of hepatic encephalopathy presented with symmetrical lower limb distal weakness, sensory ataxia, thickened palpable nerves, mood disturbances for seven years, and a family history of schizophreniform disorders. Nerve conduction studies showed demyelinating sensorimotor polyradiculoneuropathy. CSF analysis showed mild albumino-cytological dissociation. MRI brain and lumbosacral plexus showed thickened fifth cranial nerves and lumbosacral roots...
March 26, 2024: Clinical Neurology and Neurosurgery
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