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Journals JGH Open : An Open Access Jour...

JGH Open : An Open Access Journal of Gastroenterology and Hepatology

https://read.qxmd.com/read/38533237/hot-avulsion-versus-argon-plasma-coagulation-for-the-management-of-the-non-ensnarable-polyp-a-multicenter-randomized-controlled-trial
#1
JOURNAL ARTICLE
Chloe Attree, Ravinder Ogra, Ian F Yusoff, Alan C Moss, Angela Jacques, Gregor Brown, Sina Alexander, Marios Efthymiou, Spiro Raftopoulos
BACKGROUND AND AIM: Snare resection of nonlifting colonic lesions often requires supplemental techniques. We compared the success rates of neoplasia eradication using hot avulsion and argon plasma coagulation in colonic polyps when complete snare polypectomy had failed. METHODS: Polyps that were not completely resectable by snare polypectomy were randomized to argon plasma coagulation or hot avulsion for completion of resection. Argon plasma coagulation was delivered using a forward shooting catheter, using a nontouch technique (flow 1...
March 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38523708/a-systematic-review-with-meta-analysis-efficacy-and-safety-of-potassium-competitive-acid-blocker-compared-with-proton-pump-inhibitor-in-the-maintenance-of-healed-erosive-esophagitis
#2
REVIEW
Daniel M Simadibrata, Elvira Lesmana, Muhammad I A Pratama, Adrianus J Sugiharta, Afiah S Winarizal, Yeong Y Lee, Ari F Syam
INTRODUCTION: Proton pump inhibitor (PPI) is the mainstay therapy for the maintenance of healed erosive esophagitis (EE). It is unknown whether potassium-competitive acid blockers (PCABs) are more efficacious and safer than PPIs. METHODS: Only randomized controlled trials (RCTs) comparing PCABs to PPIs in the maintenance of healing rates of endoscopically proven healed EE and indexed in MEDLINE, EMBASE, and CENTRAL until 3 February 2024, were included. A fixed-effects model meta-analysis was performed to pool primary efficacy outcome (maintenance of healing rates at week 24) and safety data (any treatment-emergent adverse event or TEAE)...
March 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38486877/prediction-of-severity-of-dengue-infection-in-children-based-on-hepatic-involvement
#3
JOURNAL ARTICLE
Rubaiyat Alam, Kaniz Fathema, Afsana Yasmin, Urmi Roy, Kamal Hossen, Md Rukunuzzaman
BACKGROUND AND AIM: To assess the spectrum of hepatic involvement in children with dengue fever (DF) and prediction of severity of dengue infection by early detection of elevated liver enzymes. METHODS: This prospective observational study was conducted at a tertiary care hospital from June 2019 to September 2019. Children admitted with DF were included. Severity of DF was graded as dengue without warning sign (DNWS), with warning sign (DWS), and severe dengue fever (SDF) according to WHO criteria...
March 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38486876/antimicrobial-therapy-outcomes-in-acute-cholangitis-hilar-multiple-obstructions-versus-single-hilar-and-common-bile-duct-obstructions
#4
JOURNAL ARTICLE
Sakue Masuda, Yoshinori Imamura, Ryuhei Jinushi, Jun Kubota, Karen Kimura, Makomo Makazu, Ryo Sato, Makoto Kako, Masahiro Kobayashi, Haruki Uojima, Chikamasa Ichita, Kazuya Koizumi
BACKGROUND AND AIM: The appropriate duration of antimicrobial therapy for acute cholangitis (AC) arising from multiple hilar biliary obstructions as opposed to simple obstruction in the extrahepatic bile duct has not been established. This study assessed the efficacy of the duration of antimicrobial treatments in the Tokyo Guidelines 2018 for AC based on the cause and site of obstruction. METHODS: This single-center retrospective study involved patients with AC who underwent successful biliary drainage and completed a 7-day or shorter antimicrobial treatment...
March 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38486875/efficacy-and-safety-of-pinaverium-bromide-as-an-add-on-therapy-in-refractory-dyspepsia-a-randomized-controlled-trial
#5
JOURNAL ARTICLE
Thansita Kamolsripat, Nithi Thinrungroj, Kanokwan Pinyopornpanish, Phuripong Kijdamrongthum, Apinya Leerapun, Taned Chitapanarux, Satawat Thongsawat, Ong-Ard Praisontarangkul, Suwalee Pojchamarnwiputh
BACKGROUND AND AIM: Functional dyspepsia (FD) remains a therapeutic challenge, and the efficacy of antispasmodic agents as adjunctive therapy is not well established. This study aimed to evaluate the efficacy and safety of pinaverium bromide added to omeprazole in treating refractory FD. METHODS: We conducted a randomized, placebo-controlled trial in patients with refractory dyspepsia. Participants were randomly assigned to receive pinaverium (50 mg, 3 times/day, n = 36) or placebo ( n  = 36) in addition to omeprazole for 8 weeks...
March 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38444634/patterns-of-vitamin-d-testing-and-supplementation-for-children-with-inflammatory-bowel-disease-in-australasia
#6
JOURNAL ARTICLE
Angharad Vernon-Roberts, Andrew S Day
BACKGROUND AND AIM: For children with inflammatory bowel disease (IBD), optimal levels of vitamin D are ascribed anti-inflammatory and essential immune system roles that are associated with reduced disease activity, lower postoperative recurrence, and higher quality of life. International guidelines for vitamin D testing and supplementation provide inconsistent recommendations. The aim of this study was to survey Australasian pediatric gastroenterologists to ascertain current practices of vitamin D testing and supplementation for children with IBD...
March 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38444633/is-there-any-association-between-celiac-disease-myelodysplastic-symdrome-and-primary-sclerosing-cholangitis-a-rare-case-report
#7
Suaad Hamsho, Moudar Al Hariri, Bilal Sleiay, Abdul Hadi Daher Alhussen, Mouhammed Sleiay
Celiac disease (CD) is an autoimmune disease characterized by a specific serological and histological profile. Hematological findings are one of the most common presentations and can sometimes be the only manifestation of the disease. In patients with unexplained isolated hematological abnormalities, a high index of suspicion for CD is necessary. A 33-year-old woman was admitted to the Department of Gastroenterology and Hepatology because of abdominal pain and fatigue. She was diagnosed with myelodysplastic syndrome...
March 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38444632/use-of-virtual-reality-in-patient-education-program-to-reduce-anxiety-in-upper-gastrointestinal-endoscopy-a-randomized-controlled-trial
#8
JOURNAL ARTICLE
Surachet Siripongsaporn, Karn Yongsiriwit, Kittithat Tantitanawat, Sakkarin Chirapongsathorn
BACKGROUND AND AIM: Virtual reality (VR) provides an immersive image-viewing experience that has recently been expanding its use in clinical medicine. We aimed to examine a patient education program by VR to reduce anxiety in patients undergoing esophagogastroduodenoscopy (EGD). METHODS: We conducted a randomized controlled trial and consecutively enrolled patients who had an indication for unsedated EGD with topical anesthesia. Patients were randomly assigned to use Oculus GO with three-dimensionally specific software content (a stand-alone VR headset) for patient education or standard patient education using oral information (the control group) before EGD...
March 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38415059/transplant-hepatology-and-diversity-a-decade-long-analysis-2013-2022
#9
JOURNAL ARTICLE
Abdulmalik Saleem, Mahfujul Z Haque, Saif Affas, Maaz Munawar, Syed-Mohammed Jafri
Diversity among physicians has been shown to positively impact patient care. Physicians from minority backgrounds are more likely to serve underserved communities and be involved in health disparities research. Efforts to increase the proportion of underrepresented minorities and women in medicine will help prepare a physician workforce that best cares for a diversifying nation. The purpose of this paper was to highlight trends in sex and ethnic representation among incoming U.S. transplant hepatology trainees over a 10-year period...
February 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38405186/low-thyroid-function-is-associated-with-metabolic-dysfunction-associated-steatotic-liver-disease
#10
JOURNAL ARTICLE
Shuo Wang, Ding Xia, Hong Fan, Zhenqiu Liu, Ruilin Chen, Chen Suo, Tiejun Zhang
BACKGROUND AND AIM: Metabolic dysfunction-associated steatotic liver disease (MASLD) is recently introduced to better highlight the pathogenic significance of cardiometabolic dysfunction, as compared with non-alcoholic fatty liver disease. This study aimed to investigate the association between low thyroid function and MASLD in the new context. METHODS: We recruited 2901 participants for our retrospective cohort study from 2016 to 2021. Participants were divided into strict-normal thyroid function and low thyroid function groups (low-normal thyroid function, subclinical hypothyroidism) based on initial thyroid stimulating hormone (TSH) levels, respectively...
February 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38405185/prospective-study-on-planned-biliary-stent-placement-to-treat-small-common-bile-duct-stones
#11
JOURNAL ARTICLE
Shuzo Terada, Shinya Kawaguchi, Eiji Nakatani, Atsuko Inagawa, Tomoki Hikichi, Shodai Takeda, Yuya Ishiguro, Hirotaka Kashima, Taiyo Hirata, Shinya Ikeda, Kazuhisa Asahara, Tatsunori Satoh, Yuichi Masui, Masanori Matsuda, Ryosuke Itai, Asami Kawai, Shinya Endo, Takafumi Kurokami, Naofumi Shirane, Kazuya Ohno
AIMS: Small common bile duct stones are known to occasionally clear spontaneously. This study aimed to prospectively assess the role of biliary stent placement in promoting the spontaneous clearance of small common bile duct stones. METHODS AND RESULTS: We analyzed patients presenting with common bile duct stones of ≤5 mm diameter between June 2020 and May 2022. The exclusion criteria included asymptomatic patients, biliary pancreatitis, altered gastrointestinal anatomy, bile duct strictures (malignant or benign), and a history of EST...
February 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38389719/semaglutide-improves-metabolic-dysfunction-associated-steatohepatitis-a-10-year-retrospective-study
#12
JOURNAL ARTICLE
Parth Shah, Megan White, Alex Sievert, Alexander Conway, Adam Kneepkens, Gregory Sayuk, Mauricio Lisker-Melman, Jill Elwing
BACKGROUND AND AIMS: Semaglutide has been studied in patients with metabolic dysfunction-associated steatohepatitis (MASH) due to potential benefit from weight loss on liver inflammation. However, preclinical studies suggest that MASH improvement may be independent of weight loss. We aim to assess the impact of semaglutide on MASH in relation to weight loss. METHODS: This retrospective study included 420 patients with diabetes on semaglutide for at least 12 months between 2011 and 2022...
February 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38380260/suboptimal-reliability-of-fib-4-and-nafld-fibrosis-scores-for-staging-of-liver-fibrosis-in-general-population
#13
JOURNAL ARTICLE
Rawi Hazzan, Nur Abu Ahmad, Abu Shqara Habib, Igbaria Saleh, Neeman Ziv
BACKGROUND AND AIM: The burden and incidence of liver cirrhosis are increasing worldwide. Early detection of liver fibrosis would help in early interventions and preventing the progression of fibrosis and cirrhosis. The accepted noninvasive markers for liver fibrosis staging, namely fibrosis-4 (FIB-4) and nonalcoholic fatty liver disease fibrosis score (NFS), have shown inconsistent performance for detecting the fibrosis stage. We aimed to evaluate the efficacy of FIB-4 score and NFS for the detection of liver fibrosis in the general population...
February 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38370130/histomolecular-profile-of-helicobacter-pylori-strains-circulating-in-brazzaville-congo
#14
JOURNAL ARTICLE
Bienvenu H Atipo-Ibara, Anicet Boumba, Atipo Ibara Ollandzobo Ikobo, Arnaud Mongo-Onkouo, Jile F Mimiesse Mounamou, Ngala A Itoua-Ngaporo, Donatien Moukassa, Blaise I Atipo Ibara
BACKGROUND AND AIM: Helicobacter pylori (Hp) infection is a real public health problem in the Congo. We aimed study the histomolecular profile of Hp strains circulating in Brazzaville, Congo, in order to contribute to the improvement of Hp-infected patients in the country. METHODS: This was an analytical-transversal study carried out from January to November 2020 (i.e. a study period of 11 months) in the endoscopy centers of Brazzaville as well as the molecular biology and anatomopathology laboratories of Pointe-Noire and Oyo...
February 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38361665/potential-drug-induced-constipation-a-retrospective-study-using-a-japanese-claims-database
#15
JOURNAL ARTICLE
Yusuke Karasawa, Kazutaka Nozawa, Atsushi Nakajima
BACKGROUND AND AIM: Detailed clinical information regarding drug-induced constipation (DIC) is limited. This study aimed to investigate the real-world situation of DIC. METHODS: This retrospective study used data from a Japanese claims database registered from 2014 to 2021. The constipation cohort included subjects with at least one record of treated constipation, while the non-constipation cohort was selected through random stratified sampling method, to match the constipation cohort by gender...
February 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38344252/efficacy-and-safety-of-pantoprazole-and-itopride-in-patients-with-overlap-of-gastroesophageal-reflux-disease-and-dyspepsia-a-prospective-open-label-single-arm-pilot-study
#16
JOURNAL ARTICLE
Sundeep Lakhtakia, Aniruddha P Singh, Neeraj Singla, Sana F Memon, Duvvur N Reddy
BACKGROUND AND AIM: Combining proton pump inhibitors (PPIs) with prokinetics can provide synergistic action in patients with gastroesophageal reflux disease (GERD) and overlapping dyspepsia, but data regarding this is lacking. METHODS: This single-center, prospective study evaluated the efficacy and safety of 6-week treatment with fixed-drug combination (FDC) of pantoprazole (PPI) and itopride (prokinetic) in 50 patients with ≥3 month history of GERD and overlapping dyspepsia refractory to pantoprazole...
February 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38283070/sarcopenia-and-frailty-in-inflammatory-bowel-disease-emerging-concepts-and-evidence
#17
REVIEW
Pardhu B Neelam, Alka Sharma, Vishal Sharma
Sarcopenia is a condition marked by progressive loss of skeletal muscle mass and function while frailty is a multidimensional concept characterized by diminished physiological reserve and increased vulnerability to stressors. Both of these were previously considered as related to aging and shown to impact the quality of life and carry prognostic significance. Emerging data show that both sarcopenia and frailty carry similar relevance in chronic illness. Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract and malnourishment, both of which contribute to the development of sarcopenia by increasing protein breakdown and reducing protein synthesis...
January 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38268965/immunoglobulin-g4-related-disease-multiple-organ-occupation-on-ct
#18
Luyao Ma, Qian Zhang, Mengyao Zhang, Junjie Hao, Zhenjing Jin
One case involved a 61-year-old woman who was admitted to hospital with liver occupation, subsequently found multiple organ occupation, and was eventually pathologically identified as having immunoglobulin G4-related disease.
January 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38268964/efficacy-of-hemostatic-gel-for-perioperative-bleeding-and-prevention-of-delayed-bleeding-of-cold-snare-polypectomy-under-anticoagulant
#19
JOURNAL ARTICLE
Naohisa Yoshida, Osamu Dohi, Yoshikazu Inagaki, Yuri Tomita, Hikaru Hashimoto, Reo Kobayashi, Ken Inoue, Ryohei Hirose, Yasutaka Morimoto, Yutaka Inada, Takaaki Murakami, Yoshito Itoh
BACKGROUND AND AIM: A hemostatic gel, PuraStat (3-D Matrix, Tokyo, Japan), is used for various gastrointestinal hemostasis. In this study, we analyzed the efficacy of PuraStat for perioperative bleeding (POB) and prevention of delayed bleeding (DB) to colorectal cold snare polypectomy (CSP) with continuous anticoagulant. METHODS: This was a single-center, retrospective study. Subjects were lesions of 2-9 mm under continuous anticoagulant from 2021 to 2023 and treated with PuraStat for POB...
January 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38268963/drug-related-a-case-of-idiopathic-mesenteric-phlebosclerosis-combined-with-calcification-of-the-esophageal-veins
#20
Chang Liu, Li Li
Idiopathic mesenteric phlebosclerosis (IMP) is characterized by mesenteric vein calcification and ischemic bowel disease. We describe a unique clinical case of IMP in a patient with a history of oral administration of various drugs, including traditional Chinese medicines (mainly selfheal), vitamin D, and calcium supplements. The disease was not diagnosed in its early stages and was later detected because of the initial symptoms of chest tightness and difficulties in swallowing. During medical examination, esophageal venous sinuses were found through gastroscopy, and CT revealed thickening and widespread calcification of the colonic wall (esophageal wall calcification)...
January 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
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