Journals Tropical Medicine and Infectio...

Tropical Medicine and Infectious Disease
Khadija N Omar, Andre Coetzer, Maulid Hamdu, Ayla J Malan, Ali Z Moh'd, Talib S Suleiman, Louis H Nel
Tools and resources that could increase dog vaccination coverage have become increasingly critical towards progressing the goal to eliminate dog-mediated human rabies by 2030. In this regard, dog collars that are fitted during vaccination campaigns could potentially enhance owner participation. The use of dog collars will, however, increase the cost per dog vaccinated and the impact and benefit of this practice should be elucidated. This study evaluated the impact of dog collars by testing the perception and related behavioural influences in communities in Zanzibar...
August 21, 2023: Tropical Medicine and Infectious Disease
Indira Shrestha, Sulekha Shrestha, Mathavaswami Vijayageetha, Pramesh Koju, Saugat Shrestha, Rony Zachariah, Mohammed Ahmed Khogali
(1) Background : Surgical antibiotic prophylaxis (SAP) is important for reducing surgical site infections. The development of a dedicated hospital SAP guideline in the Dhulikhel Hospital was a recommendation from a baseline study on SAP compliance. Compliance with this new guideline was enhanced through the establishment of a hospital committee, the establishment of an antibiotic stewardship program and the funding and training of healthcare professionals. Using the baseline and a follow-up study after introducing dedicated hospital SAP guidelines, we compared: (a) overall compliance with the SAP guidelines and (b) the proportion of eligible and non-eligible patients who received initial and redosing of SAP; (2) Methods : A before-and-after cohort study was conducted to compare SAP compliance between a baseline study (July 2019-December 2019) and a follow-up study (January 2023-April 2023); (3) Results : A total of 874 patients were in the baseline study and 751 in the follow-up study...
August 18, 2023: Tropical Medicine and Infectious Disease
Timothy Riddles, Daniel Judge
BACKGROUND: Community-acquired Acinetobacter pneumonia (CAAP) typically presents with rapid progression to fulminant disease and is complicated by high mortality. Australian epidemiological studies are few. METHODS: We conducted a retrospective study on bacteraemic cases of CAAP over twenty years (2000-2019) in North Queensland. Cases were selected on microbiologic, clinical, and radiographic parameters. Data on patient demographics were obtained, along with microbial, antibiotic, mortality and climatic data...
August 18, 2023: Tropical Medicine and Infectious Disease
Hashim A Mahdi, Mohammed Alluhidan, Abdulrahman B Almohammed, Mohammad Alfelali, Ramon Z Shaban, Robert Booy, Harunor Rashid
This systematised review aims to compare the epidemiological patterns of Hajj-acquired airborne infections among pilgrims from low and middle-income countries (LMIC) versus those from high-income countries (HIC). A PubMed search was carried out for all published articles before February 2023, using a combination of MeSH terms and text words. The Newcastle-Ottawa Scale (NOS) was used to assess data quality. From a total of 453 titles identified, 58 studies were included in the review (LMIC = 32, and HIC = 26)...
August 17, 2023: Tropical Medicine and Infectious Disease
Jowita S Niczyporuk, Wojciech Kozdrun, Agnieszka Czujkowska, Yannick Blanchard, Mariteragi Helle, Nolwenn M Dheilly, Gaelle Gonzalez
The summer temperatures recorded in Poland in 2022 were among the highest in over 30 years and, combined with higher-than-expected rainfall, gave the impression of an almost tropical climate. Such climatic conditions were ideal for the transmission of vector-borne zoonotic diseases such as West Nile fever. In northeastern Poland, in the Mazowieckie region, the Polish event-based surveillance network reported increased fatalities of free-living hooded crows ( Corvus corone cornix) . West Nile virus (WNV) lineage 2 was identified for the first time as the etiological agent responsible for the death of the birds...
August 16, 2023: Tropical Medicine and Infectious Disease
Daniil Shauer, Ofelya Petrosyan, Manik Gemilyan, Edward M Kamau, Pruthu Thekkur, Olga Goncharova, Kalmambetova Gulmira, Bolot Kyrbashov, Kylychbek Istamov, Meder Kadyrov, Ewan Wilkinson
This study evaluated the effectiveness of an electronic system for managing individuals with drug-sensitive pulmonary tuberculosis in the Kyrgyz Republic. This cohort study used programmatic data. The study included people registered on the paper-based system in 2019 and 302 people registered on both the electronic and the paper-based systems between June 2021 and May 2022. The data from the 302 individuals were used to assess the completeness of each form of record and the concordance of the electronic record with the paper-based system...
August 16, 2023: Tropical Medicine and Infectious Disease
Vinoth Kumarasamy, Arutchelvan Rajamanikam, Deepa Anbazhagan, Wahib Mohammed Atroosh, Meram Azzani, Vetriselvan Subramaniyan, Syamsa Rizal Abdullah
Blastocystis spp. is a unicellular enteric protozoan parasite in humans with a controversial role in disease etiology. It is common in developing countries among immunocompromised patients and people who have close contact with animals. In this study, we have systematically reviewed previous studies on the distribution and genotypes of human Blastocystis infection in Peninsular Malaysia. Studies examining the prevalence of Blastocystis in diverse demographics, including rural, urban, comorbid conditions, and high-risk populations, were taken into consideration...
August 15, 2023: Tropical Medicine and Infectious Disease
Saskia van Henten, Fentaw Bialfew, Seid Hassen, Feleke Tilahun, Johan van Griensven, Seid Getahun Abdela
Cutaneous leishmaniasis (CL) is common in Ethiopia, but the national guideline does not offer specific treatment recommendations. Consequently, different treatment regimens are used in the country, without quality evidence. In Boru Meda Hospital, sodium stibogluconate (SSG) is routinely used in combination with allopurinol for systemic CL treatment, although evidence on its effectiveness is limited. An observational cohort study was carried out to document clinical treatment outcomes in patients receiving SSG/allopurinol at the end of each 28-day treatment cycle and after 180 days...
August 14, 2023: Tropical Medicine and Infectious Disease
Inacio Mandomando, Jason M Mwenda, Tomoka Nakamura, Linda de Gouveia, Anne von Gottberg, Brenda A Kwambana-Adams, Martin Antonio, Augusto Messa, David Litt, Shila Seaton, Goitom Gebremedhin Weldegebriel, Joseph Nsiari-Muzeyi Biey, Fatima Serhan
(1) Background: Laboratories supporting the invasive bacteria preventable disease (IB-VPD) network are expected to demonstrate the capacity to identify the main etiological agents of pediatric bacterial meningitis (PBM) ( Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae ) on Gram stains and in phenotypic identification. Individual reports of sentinel site (SSL), national (NL) and regional reference (RRL) laboratories participating in the World Health Organization (WHO)-coordinated external quality assessment, distributed by the United Kingdom National External Quality Assessment (EQA) Services (UK NEQAS) for Microbiology between 2014 and 2019 were analyzed...
August 14, 2023: Tropical Medicine and Infectious Disease
Kylychbek Istamov, Mher Beglaryan, Olga Goncharova, Konushbek Sakmamatov, Bolot Kyrbashov, Mukadas Mamytova, Indira Zairova, Gulzat Alumkylova, Divya Nair
Migrants are at increased risk of developing tuberculosis (TB) and have poor treatment outcomes. The National TB program (NTP) of the Kyrgyz Republic recognizes two types of migrants: internal (intra-country) and external (inter-country) migrants. This cohort study compared the characteristics, timeliness of diagnosis and treatment initiation, and treatment outcomes of TB patients (internal migrant vs. external migrant vs. non-migrant) identified during treatment in the country in 2021. The TB treatment register and treatment cards of 5114 patients (156 internal, 430 external, and 4528 non-migrants) were reviewed...
August 13, 2023: Tropical Medicine and Infectious Disease
Malaisamy Muniyandi, Paranchi Murugesan Ramesh, William A Wells, Umesh Alavadi, Suvanand Sahu, Chandrasekaran Padmapriyadarsini
OBJECTIVE: To measure the economic impacts of the longer pre-XDR-TB treatment regimen and the shorter BEAT-TB India regimen. METHODS: In the current study, the economic impacts of the current 18-month pre-XDR-TB treatment regimen and the 6-9 month BEAT-TB regimen were evaluated using an economic model via a decision tree analysis from a societal perspective. The incremental costs and quality-adjusted life years (QALYs) gained from the introduction of the BEAT-TB regimen for pre-XDR-TB patients were estimated...
August 11, 2023: Tropical Medicine and Infectious Disease
Jeyanthi Suppiah, Ernie Zuraida Ali, Mohd Khairul Nizam Mohd Khalid, Sumarni Mohd Ghazali, Kok Keng Tee, Murni Maya Sari Zulkifli, Nuraisyah Ramli, Amir Hussin Adiee, Muhamad Nurrani Ramly, Fionie Robert, Sarbhan Singh Lakha Singh, Rozainanee Mohd Zain, Ravindran Thayan
Dengue virus serotype 4 (DENV-4) has been the rarest circulating serotype in Malaysia, resulting in it being an understudied area. A recent observation from institutional surveillance data indicated a rapid increase in DENV-4-infected cases. The present study aimed to investigate the resurgence of DENV-4 in relation to the demographic, clinical and genomic profiles of 75 retrospective dengue samples. First, the demographic and clinical profiles obtained between 2017 and July 2022 were statistically assessed...
August 11, 2023: Tropical Medicine and Infectious Disease
Christin Körsten, Ana Vasić, Amira A Al-Hosary, Birke A Tews, Cristian Răileanu, Cornelia Silaghi, Mandy Schäfer
The increasing threat of arboviruses such as West Nile virus (WNV) and Usutu virus (USUV) requires the fast and efficient surveillance of these viruses. The examination of mosquitoes takes up an important part; however, these investigations are usually very time-consuming. An alternative sample type for arbovirus surveillance might be mosquito excreta. In order to determine the excretion dynamics under laboratory conditions, laboratory colonies of Aedes vexans and Culex pipiens biotype molestus were infected with WNV, USUV or tick-borne encephalitis virus (TBEV)...
August 11, 2023: Tropical Medicine and Infectious Disease
Bolot Kyrbashov, Aizat Kulzhabaeva, Abdullaat Kadyrov, Atyrkul Toktogonova, Collins Timire, Srinath Satyanarayana, Kylychbek Istamov
The Kyrgyz Republic is a high-burden country for rifampicin resistant/multi-drug resistant tuberculosis (RR/MDR-TB). TB control efforts rely on early diagnosis and initiation of people on effective regimens. We studied the interval from diagnosis of RR-TB to starting treatment and risk factors for unsuccessful outcomes among people who started RR/MDR-TB treatment in 2021. We conducted a cohort study using country-wide programme data and used binomial regression to determine associations between unsuccessful outcomes and predictor variables...
August 10, 2023: Tropical Medicine and Infectious Disease
Samuel Alie Konteh, Fatmata Isatu Bangura Turay, Amara Leno, Srinath Satyanarayana, Divya Nair, Mohamed Alpha Bah, Salam Saidu, David Sellu-Sallu, Sahr Raymond Gborie, Sorie Mohamed Kamara, Amadu Tejan Jalloh, Joseph Sam Kanu, Kadijatu Nabie Kamara, Matilda Mattu Moiwo, Esther Dsani, Noelina Nantima
In Sierra Leone, two operational research (OR) studies in 2019 and 2021 showed deficiencies in the data being captured by the Integrated Animal Disease Surveillance and Reporting (IADSR) system. This third OR study was conducted in 2023 to assess whether the second OR study's results and recommendations were disseminated with the key stakeholders, the uptake of the recommendations, improvements in data capture in the IADSR system, and to describe the data on livestock disease and antimicrobial use. In 2022, on seven occasions, the authors of the second OR study disseminated the study's findings...
August 10, 2023: Tropical Medicine and Infectious Disease
Ilaria Varotto-Boccazzi, Sara Epis, Giulia Maria Cattaneo, Noemi Guerrini, Alessandro Manenti, Diego Rubolini, Paolo Gabrieli, Domenico Otranto, Gianvincenzo Zuccotti, Emanuele Montomoli, Claudio Bandi
The mucosal immune system plays a pivotal role in the control of infections, as it represents the first line of defense against most pathogens, from respiratory viruses to intestinal parasites. Mucosal vaccination is thus regarded as a promising strategy to protect animals, including humans, from infections that are acquired by ingestion, inhalation or through the urogenital system. In addition, antigens delivered at the mucosal level can also elicit systemic immune responses. Therefore, mucosal vaccination is potentially effective also against systemic infections acquired through non-mucosal routes, for example, through the bite of hematophagous insects, as in the case of leishmaniasis, a widespread disease that affects humans and dogs...
August 9, 2023: Tropical Medicine and Infectious Disease
Nayore Tamie Takamiya, Luana Aparecida Rogerio, Caroline Torres, João Augusto Franco Leonel, Geovanna Vioti, Tricia Maria Ferreira de Sousa Oliveira, Karoline Camila Valeriano, Gabriane Nascimento Porcino, Isabel Kinney Ferreira de Miranda Santos, Carlos H N Costa, Dorcas Lamounier Costa, Tauana Sousa Ferreira, Rodrigo Gurgel-Gonçalves, João Santana da Silva, Felipe Roberti Teixeira, Roque Pacheco De Almeida, José M C Ribeiro, Sandra Regina Maruyama
Visceral leishmaniasis (VL) is a neglected disease considered a serious public health problem, especially in endemic countries. Several studies have discovered monoxenous trypanosomatids ( Leptomonas and Crithidia ) in patients with VL. In different situations of leishmaniasis, investigations have examined cases of co-infection between Leishmania spp. and Crithidia spp. These coinfections have been observed in a wide range of vertebrate hosts, indicating that they are not rare. Diagnostic techniques require improvements and more robust tools to accurately detect the causative agent of VL...
August 8, 2023: Tropical Medicine and Infectious Disease
Yuhao Lin, Tianmu Chen
In recent years, emerging infectious disease outbreaks have placed significant health and socioeconomic burdens upon the population [...].
August 8, 2023: Tropical Medicine and Infectious Disease
Anatoly V Kondrashin, Lola F Morozova, Ekaterina V Stepanova, Natalia A Turbabina, Maria S Maksimova, Alina S Anikina, Ariyo Shahin-Jafari, Aleksandr E Morozov, Dmitry V Mikhaylov, Yulia D Kupriyanova, Evgeny N Morozov
Currently, more than 500,000 cases of various helminthes in humans are reported annually in the Russian Federation. This figure may not reflect the true incidence of helminthes, as only nine separate nosological forms are compulsory notifiable. The rest of the species of detected helminthes are included in a separate category of "other helminthes" or "rare helminthes". The bulk of the latter is represented by the helminthes with a rate of incidence that does not exceed one case per 100,000 people. This review is based on data derived from publications in the Russian language, both from the Russian Federation and international, as well as data available from various health treatment facilities in Russia...
August 8, 2023: Tropical Medicine and Infectious Disease
Nasim Almasian Tehrani, Leila Azimi, Shahnaz Armin, Neda Soleimani, Fatemeh Fallah, Abdollah Karimi, Bibi Shahin Shamsian, Shiva Nazari, Masoud Alebouyeh
OBJECTIVE: Carbapenem-resistant Enterobacteriaceae (CR E ) infection is life-threatening, especially for immunocompromised children. The source tracking of CR E could prevent bacteremia during hospitalization. In this study, the intestinal colonization of CR E and their translocation to blood were investigated. METHODS: Stool samples from immunocompromised pediatric patients were collected after admission, and secondary stool and blood samples were collected in case of fever...
August 7, 2023: Tropical Medicine and Infectious Disease
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