Xinyan Zhao, Yan Wang, Rongtao Lai, Xiaojin Wang, Yuecheng Yu, Min Li, Hong Zhao, Zikun Ma, Mengqi Li, Tiantian Guo, Xiao Han, Yao Meng, Mengmeng Zhang, Yu Su, Kunyan Hao, You Deng, Yuanyuan Kong, Zhenyu Li, Qing Xie, Wen Xie, Chengwei Chen, Jidong Jia
BACKGROUND AIMS: The Revised Electronic Causality Assessment Method (RECAM), a computerized update of the Roussel Uclaf Causality Assessment Methodology (RUCAM), was recently proposed. In this study, we validated and compared the utility of the RECAM and RUCAM in Chinese patients with a single conventional or herbal agent-induced liver injury. METHODS: In this retrospective multicenter cohort of well-established DILI and non-DILI patients from 5 centers in China, the diagnostic performance of the RUCAM and RECAM was compared by AUC analysis...
April 1, 2024: Hepatology Communications