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Journal of Comorbidity

John Sina Moin, Rahim Moineddin, Ross Edward Grant Upshur
There is growing evidence to suggest that multimorbidity is not only a consequence of aging but also other environmental risk factors such as socio-economic status and social marginalization. In this study, the prevalence of multimorbidity was examined (defined as the simultaneous occurrence of two or more chronic morbidities) by age, gender and the Ontario Marginalization index (material deprivation, residential instability, dependency and ethnic concentration). With a cross-sectional design, 2015 data on 18 morbidities from 12,516,587 residents of the province of Ontario, Canada, were analysed...
January 2018: Journal of Comorbidity
Ingmar Schäfer, Hanna Kaduszkiewicz, Truc Sophia Nguyen, Hendrik van den Bussche, Martin Scherer, Gerhard Schön
Background: Multimorbidity is prevalent and related to adverse outcomes. The effect on mortality is disputed, possibly because studies show differences in the diseases which operationalize multimorbidity. The aim of this study is to analyze the effects of three multimorbidity patterns (representing subgroups of diseases) on mortality. Methods: We conducted a longitudinal observational study based on insurance claims data of ambulatory care from 2005 to 2009. Analyses are based on 46 chronic conditions with a prevalence ≥1%...
January 2018: Journal of Comorbidity
Gustavo Dias Ferreira, José Augusto Simões, Chamara Senaratna, Sanghamitra Pati, Pierre Fernando Timm, Sandro Rodrigues Batista, Bruno Pereira Nunes
Background: Multimorbidity is the co-occurrence of two or more diseases in the same individual. One method to identify this condition at an early stage is the use of specific markers for various combinations of morbidities. Nonetheless, evidence related to physiological markers in multimorbidity is limited. Objective: The aim was to perform a systematic review to identify physiological markers associated with multimorbidity. Design: Articles available on PubMed, Register of Controlled Trials, Academic Search Premier, CINAHL, Scopus, SocINDEX, Web of Science, LILACS, and SciELO, from their inception to May 2018, were systematically searched and reviewed...
January 2018: Journal of Comorbidity
T G Willadsen, V Siersma, D R Nicolaisdóttir, R Køster-Rasmussen, D E Jarbøl, S Reventlow, S W Mercer, N de Fine Olivarius
Background: Knowledge about prevalent and deadly combinations of multimorbidity is needed. Objective: To determine the nationwide prevalence of multimorbidity and estimate mortality for the most prevalent combinations of one to five diagnosis groups. Furthermore, to assess the excess mortality of the combination of two groups compared to the product of mortality associated with the single groups. Design: A prospective cohort study using Danish registries and including 3...
January 2018: Journal of Comorbidity
Sandra Pouplier, Maria Åhlander Olsen, Tora Grauers Willadsen, Håkon Sandholdt, Volkert Siersma, Christen Lykkegaard Andersen, Niels de Fine Olivarius
Objective: The aims of this study were to (1) quantify the development and composition of multimorbidity (MM) during 16 years following the diagnosis of type 2 diabetes and (2) evaluate whether the effectiveness of structured personal diabetes care differed between patients with and without MM. Research design and methods: One thousand three hundred eighty-one patients with newly diagnosed type 2 diabetes were randomized to receive either structured personal diabetes care or routine diabetes care...
January 2018: Journal of Comorbidity
Lauren E Griffith, Andrea Gruneir, Kathryn A Fisher, Kathryn Nicholson, Dilzayn Panjwani, Christopher Patterson, Maureen Markle-Reid, Jenny Ploeg, Arlene S Bierman, David B Hogan, Ross Upshur
Background: There are multiple multimorbidity measures but little consensus on which measures are most appropriate for different circumstances. Objective: To share insights gained from discussions with experts in the fields of ageing research and multimorbidity on key factors to consider when measuring multimorbidity. Design: Descriptive study of expert opinions on multimorbidity measures, informed by literature to identify available measures followed by a face-to-face meeting and an online survey...
January 2018: Journal of Comorbidity
Samantha L Hider, Milica Bucknall, Kelly Cooke, Kendra Cooke, Andrew G Finney, Dave Goddin, Emma L Healey, Susie Hennings, Daniel Herron, Clare Jinks, Martyn Lewis, Annabelle Machin, Christian Mallen, Simon Wathall, Carolyn A Chew-Graham
Background: Patients with inflammatory rheumatic conditions such as rheumatoid arthritis, polymyalgia rheumatica and ankylosing spondylitis are at increased risk of common comorbidities such as cardiovascular disease, osteoporosis and anxiety and depression which lead to increased morbidity and mortality. These associated morbidities are often un-recognized and under-treated. While patients with other long-term conditions such as diabetes are invited for routine reviews in primary care, which may include identification and management of co-morbidities, at present this does not occur for patients with inflammatory conditions, and thus, opportunities to diagnose and optimally manage these comorbidities are missed...
2018: Journal of Comorbidity
Maureen Markle-Reid, Jenny Ploeg, Ruta Valaitis, Wendy Duggleby, Kathryn Fisher, Kimberly Fraser, Rebecca Ganann, Lauren E Griffith, Andrea Gruneir, Carrie McAiney, Allison Williams
Background: The goal of the Aging, Community and Health Research Unit (ACHRU) is to promote optimal aging at home for older adults with multimorbidity (≥2 chronic conditions) and to support their family/friend caregivers. This protocol paper reports the rationale and plan for this patient-oriented, cross-jurisdictional research program. Objectives: The objectives of the ACHRU research program are (i) to codesign integrated and person-centered interventions with older adults, family/friend caregivers, and providers; (ii) to examine the feasibility of newly designed interventions; (iii) to determine the intervention effectiveness on Triple Aim outcomes: health, patient/caregiver experience, and cost; (iv) to examine intervention context and implementation barriers and facilitators; (v) to use diverse integrated knowledge translation (IKT) strategies to engage knowledge users to support scalability and sustainability of effective interventions; and (vi) to build patient-oriented research capacity...
2018: Journal of Comorbidity
Kathryn Barker, Anne E Holland, Annemarie L Lee, Kathryn Ritchie, Claire Boote, Stephanie Lowe, Fiona Pazsa, Lee Thomas, Monica Turczyniak, Elizabeth H Skinner
Background: Multimorbidity, the coexistence of two or more chronic conditions, is common in clinical practice. Rehabilitation for people with multimorbidity may provide access to a rehabilitation programme that can address common symptoms and risk factors for multiple chronic diseases. Objective: The aims of this study were to (1) evaluate the feasibility of a rehabilitation programme compared to usual medical care (UMC) in people with multimorbidity and (2) gather preliminary data regarding clinical effects and impact on functional exercise capacity, activities of daily living, health-related quality of life and resource utilization...
2018: Journal of Comorbidity
Huah Shin Ng, Bogda Koczwara, David Roder, Theo Niyonsenga, Agnes Vitry
Background: The development of comorbidities has become increasingly relevant with longer-term cancer survival. Objective: To assess the pattern of comorbidities among Australian women with breast cancer treated with tamoxifen or an aromatase inhibitor. Design: Retrospective cohort study using Pharmaceutical Benefits Scheme (PBS) data (10% sample) from January 2003 to December 2014. Dispensing claims data were used to identify comorbidities and classified with the Rx-Risk-V model...
2018: Journal of Comorbidity
Tiny van Merode, Karin van de Ven, Marjan van den Akker
Background: Physicians and other healthcare professionals involved in the care of patients with multimorbidity should consider the problems these patients experience in managing their own conditions. However, treatment burden from the patient's perspective has been poorly explored, even though this might hamper treatment adherence. Objective: The present study examined the experiences of patients with multimorbidity in primary care in the Netherlands and Belgium using semi-structured interviews, with special attention to the daily life domains of treatment burden...
2018: Journal of Comorbidity
Katie I Gallacher, Ross McQueenie, Barbara Nicholl, Bhautesh D Jani, Duncan Lee, Frances S Mair
Background: Multimorbidity is common in stroke, but the risk factors and effects on mortality remain poorly understood. Objective: To examine multimorbidity and its associations with sociodemographic/lifestyle risk factors and all-cause mortality in UK Biobank participants with stroke or transient ischaemic attack (TIA). Design: Data were obtained from an anonymized community cohort aged 40-72 years. Overall, 42 comorbidities were self-reported by those with stroke or TIA...
2018: Journal of Comorbidity
Stewart W Mercer, John Gillies, Jane Gunn, Martin Fortin, Marjan van den Akker, Susan M Smith
No abstract text is available yet for this article.
2017: Journal of Comorbidity
Sidsel M Runz-Jørgensen, Michaela L Schiøtz, Ulla Christensen
Background: The prevalence of multimorbidity is increasing, creating challenges for patients, healthcare professionals, and healthcare systems. Given that chronic disease management increasingly involves eHealth, it is useful to assess its perceived value among people with multimorbidity. Objective: To explore challenges related to multimorbidity and patients' perspectives on eHealth. Design: Ten semi-structured interviews with adults, living with multimorbidity in Copenhagen, Denmark...
2017: Journal of Comorbidity
Martin Fortin, José Almirall, Kathryn Nicholson
Background: Researchers interested in multimorbidity often find themselves in the dilemma of identifying or creating an operational definition in order to generate data. Our team was invited to propose a tool for documenting the presence of chronic conditions in participants recruited for different research studies. Objective: To describe the development of such a tool. Design: A scoping review in which we identified relevant studies, selected studies, charted the data, and collated and summarized the results...
2017: Journal of Comorbidity
Martin Fortin, Tom Vansaghi, Marjan van den Akker, Jill Haught, Stewart W Mercer, Susan M Smith, Jane Gunn
No abstract text is available yet for this article.
2017: Journal of Comorbidity
Gary McLean, Stewart W Mercer
Background: Chronic migraine is common but there is limited knowledge on associated comorbidities. Objectives: To examine mental and physical comorbidities in chronic migraine and the influence of socioeconomic status in a large, nationally representative dataset. Design: Analysis of cross-sectional primary healthcare data from 1,468,404 adults in Scotland. Chronic migraine, 31 other physical conditions, and seven mental health conditions we examined...
2017: Journal of Comorbidity
Chadia Haddad, Souheil Hallit, Pascale Salameh, Tarek Bou-Assi, Marouan Zoghbi
BACKGROUND: Coronary heart disease (CHD) is a leading cause of premature death in patients with schizophrenia. CHD risk in Lebanese patients with schizophrenia remains unknown. OBJECTIVES: To (i) evaluate CHD risk of patients with schizophrenia in Lebanon; and (ii) detect the modifiable and non-modifiable factors affecting this risk. METHODS: Cross-sectional study of 329 patients with schizophrenia aged 20-75 years. Ten-year hard CHD risk was calculated using the Framingham risk score...
2017: Journal of Comorbidity
Eileen M McKinlay, Sonya J Morgan, Ben V Gray, Lindsay M Macdonald, Susan R H Pullon
BACKGROUND: The increase in multimorbidity or co-occurring chronic illnesses is a leading healthcare concern. Patients with multimorbidity require ongoing care from many different professionals and agencies, and often report a lack of integrated care. OBJECTIVE: To explore the daily help-seeking behaviours of patients with multimorbidity, including which health professionals they seek help from, how professionals work together, and perceptions and characteristics of effective interprofessional, interagency multimorbidity care...
2017: Journal of Comorbidity
Stephen P Fitzgerald, Nigel G Bean, Ravi P Ruberu
BACKGROUND: The external validity, or generalizability, of trials and guidelines has been considered poor in the context of multiple morbidity. How multiple morbidity might affect the magnitude of benefit of a given treatment, and thereby external validity, has had little study. OBJECTIVE: To provide a method of decision analysis to quantify the effects of age and comorbidity on the probability of deriving a given magnitude of treatment benefit. DESIGN: We developed a method to calculate probabilistically the effect of all of a patient's comorbidities on their underlying utility, or well-being, at a future time point...
2017: Journal of Comorbidity
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