Rafat Chowdhury, Myuri Moorthy, Lorna Smith, Christoph A Mueller, Fiona Gong, Harriet J Rogers, Marianthi-Vasiliki Papoutsaki, Tom Syer, Giorgio Brembilla, Saurabh Singh, Adam Retter, Thomas Parry, Joey Clemente, Lucy Caselton, Hassan Jeraj, Max Bullock, Manju Mathew, Teng Teng Chung, Scott Akker, Paul Chapple, Grace A Salsbury, Alan Bainbridge, David Atkinson, David G Gadian, Umasuthan Srirangalingam, Shonit Punwani
Phaeochromocytomas (PCC) and paragangliomas (PGL), cumulatively referred to as PPGLs, are neuroendocrine tumours arising from neural crest-derived cells in the sympathetic and parasympathetic nervous systems. Predicting future tumour behaviour and the likelihood of metastatic disease remains problematic as genotype-phenotype correlations are limited, the disease has variable penetrance and, to date, no reliable molecular, cellular or histological markers have emerged. Tumour metabolism quantification can be considered as a method to delineating tumour aggressiveness by utilising hyperpolarised 13 C-MR (HP-MR)...
November 2023: BJR Case Reports