Linrui Gao, Ran Wei, Shirui Qin, Yuan Tian, Wenlong Xia, Yongwen Song, Shulian Wang, Hui Fang, Yu Tang, Hao Jing, Yueping Liu, Yuan Tang, Shunan Qi, Bo Chen, Yexiong Li, Nianzeng Xing, Ningning Lu
BACKGROUND: Magnetic resonance (MR)-guided ultra-hypofractionated radiotherapy with whole-pelvic irradiation (UHF-WPRT) is a novel approach to radiotherapy for patients with high-risk (HR) and very high-risk (VHR) prostate cancer (PCa). However, the inherent complexity of adaptive UHF-WPRT might inevitably result in longer on-couch time. We aimed to estimate the delivered dose, study the feasibility and safety of adaptive UHF-WPRT on a 1.5-Tesla MR-Linac. METHODS: Ten patients with clinical stage T3a-4N0-1M0-1c PCa, who consecutively received UHF-WPRT, were enrolled prospectively...
March 2024: Chronic Diseases and Translational Medicine