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International Journal of Pediatrics & Adolescent Medicine
Fadiah Alkhattabi, Nawaf Al Faryan, Manar Alsaleh, Maureen Long, Abdullah Alkhani, Salma Alwahibah, Margarita Frederico, Raghad Alhuthil
OBJECTIVES: The purpose of this paper is to highlight the impact of a pandemic on the lives of vulnerable members of the community who have experienced or are 'at risk' of experiencing intimate family violence and child abuse in Saudi Arabia. By reviewing the experience in Saudi Arabia in the context of the international literature, the study explores similarities and differences in the impact of the pandemic on family violence. METHODS: The study investigated the impact of the COVID-19 pandemic on family violence and child abuse in Saudi Arabia by conducting a comparative analysis of the prevalence of cases, types of abuse, and geographical location of those experiencing violence between the years 2019 and 2020...
January 9, 2023: International Journal of Pediatrics & Adolescent Medicine
Mai Adnan Ezzat, Ebtsam Mohmmed Albassam, Eman Abdullah Aldajani, Raneem Abdulaziz Alaskar, Edward Bentz Devol
BACKGROUND: Early identification of childhood malnutrition is imperative to improve overall health outcomes, and more importantly, to start early intervention to decrease the risk of future complications. This study aimed to evaluate new malnutrition Z-score growth indicators for detecting pediatric malnutrition and degrees of severity and compare their accuracy with that of growth chart centiles. PATIENTS AND METHODS: This retrospective study included 475 pediatric patients from several pediatric nutrition clinics for six months...
December 2022: International Journal of Pediatrics & Adolescent Medicine
Saadiya Khan, Khawar Siddiqui, Hasan ElSolh, Abdullah AlJefri, Ali AlAhmari, Ibrahim Ghemlas, Hawazen AlSaedi, Awatif AlEnazi, Amal AlSeraihi, Mouhab Ayas
OBJECTIVES: Allogeneic hematopoietic cell transplantation (Allo-HCT) is a curative option for children with various malignant and non-malignant diseases. Most reports studied all age groups amongst children. Herein we analyzed our data in children transplanted at or less than 2-years of age. PATIENTS AND METHODS: We reviewed medical charts of 618 patients who underwent 666 transplantation at our center between 1993 and 2015. There were 340 boys and 278 girls. Median age was 0...
December 2022: International Journal of Pediatrics & Adolescent Medicine
Sami Alhajjar, Kimberly Cristobal, Janelle Vales-Yasay
No abstract text is available yet for this article.
December 2022: International Journal of Pediatrics & Adolescent Medicine
Amir Babiker, Amani Idris, Mohammed Aldawsari, Moath Abu Abah, Bothainah Alaqeel, Asim Almotawa, Emad Masuadi, Adnan AlShaikh, Moutasem Azzubi, Mohammed Al Dubayee, Ibrahim Al Alwan, Mohamad Maghnie
BACKGROUND: Post-operative pituitary insufficiency (PI) occurs in children with supra-tentorial tumors (STT) because of surgery or the mass effect of the tumor. We assessed the prevalence and clinical characteristics of STTs and predicted postoperative PI in our patients. METHODS: This retrospective cohort study included children who underwent surgery for STT in two tertiary hospitals in Saudi Arabia (2009-2019). We focused on clinical, radiological, and histopathological features of STTs...
December 2022: International Journal of Pediatrics & Adolescent Medicine
Sara Madureira Gomes, Rita Figueiredo, Ricardo Morais, Sérgia Soares, Jacinta Fonseca, Cláudia Melo, Mafalda Sampaio, Raquel Sousa
Behçet's disease (BD) is a rare systemic vasculitis with multisystemic involvement. Neurological involvement, called neuro-Behçet's disease (NBD), mostly involves the central nervous system and cerebral venous thrombosis (CVT) is the predominant neurological manifestation in the pediatric age. A 12-year-old female with a past medical history of a CVT, without an identifiable etiology, was admitted with a five-day right fronto-orbital headache. Neuroimage showed a subacute thrombosis of a right superficial sylvian vein, with indirect signs of intracranial hypertension and no imaging signs of vasculitis...
December 2022: International Journal of Pediatrics & Adolescent Medicine
Deepika Rustogi, Chetan Khare, Karunesh Kumar
Paediatric abdominal pain continues to pose a diagnostic challenge in the acute hospital care setting. We describe an eleven-year-old boy who presented to the emergency department with acute-onset, sharp abdominal pain localised to right lower quadrant. Abdominal imaging was diagnostic for epiploic appendagitis (EA), with pathognomonic 'ring sign' and 'central dot' visualised on the axial computed tomography images. He responded well to conservative treatment, including a short course of non-steroidal anti-inflammatory drugs...
December 2022: International Journal of Pediatrics & Adolescent Medicine
Ammar Fneish, Mohammad Alhasoon, Amenah Al Essa, Radha Mahlangu, Noura Alshami, Saif Alsaif, Kamal Ali
OBJECTIVE: This study aimed to investigate the association between admission hypothermia (AH), neonatal mortality and major neonatal morbidities in preterm infants <33 weeks' gestation. An additional aim of the study was to examine changes in the prevalence of admission hypothermia after the initiation of a thermoregulation quality improvement (QI) project. METHOD: This is a retrospective cohort study of preterm infants < 33 weeks' gestation born at King AbdulAziz Medical City Riyadh (KAMC-R) between January 2017 to December 2020...
December 2022: International Journal of Pediatrics & Adolescent Medicine
Abdelrazak Meliti, Wedad Gasim, Haneen Al-Maghrabi, Ghadeer Mokhtar
Embryonal tumor with multilayered rosettes (ETMR), C19MC-altered is a newly designated entity of the embryonal tumors of the central nervous system (CNS) according to the 2016 WHO classification system of CNS. Characteristically, these tumors are newly defined based on their specific molecular genetic amplification in chromosome 19q13.42 found at locus C19MC. To the best of our knowledge, we present the first reported case of ETMR in Saudi Arabian pediatric population. A 2-year-old boy presented to the hospital with generalized tonic-colonic seizure, vomiting, irritability, and inability to walk...
September 2022: International Journal of Pediatrics & Adolescent Medicine
Faisal Khan, Faaezuddin Syed, Hamna AbdulMuthalib, Nada Dammas, Saleh Al Alaiyan, Fahad Al Hazzani, AbdelHakeem Kattan, Mohammed Bin Jabr, AbdelAziz Bin Manea, Eyad Almidani
Mycophenolic acid [MPA] is a powerful inhibitor of lymphocyte proliferation. Although this drug has been used across the globe for various maternal comorbidities, multiple concerns have been raised regarding its teratogenic effects. The Food and Drug Administration has changed its category to drug category D (evidence of fetal risk) in 2007. A wide range of congenital malformations in infants born to a mother using this medication have been described in the literature, but there is no specific set pattern of these malformations...
September 2022: International Journal of Pediatrics & Adolescent Medicine
Yasuhiro Abe, Tomohiro Hirade, Daisuke Koike, Chihiro Matama, Fumihide Kato
Laryngeal web is a rare congenital or acquired disease that results in airway stenosis. Depending on the severity of atresia, patients with laryngeal web show a wide variety of symptoms ranging from asymptomatic to life-threatening respiratory dysfunction that may require emergency tracheostomy immediately after birth. We report a neonatal case of laryngeal web with 22q11.2 deletion syndrome. Post-delivery, the infant showed dysphonia and had a ventricular septal defect with characteristic craniofacial features...
September 2022: International Journal of Pediatrics & Adolescent Medicine
Pierrick Boulic, Anaïs Victor, Simon Kayemba-Kay's
Abdominal pain is a frequent complaint in children, leading them to seek medical attention. It can have several causes, though acute appendicitis is the most feared diagnosis when pain is localized in the right iliac fossa. We report a case of an 8-year-old boy with the complaint of acute abdominal pain, initially referred by his family doctor to a radiologist for an abdominal ultrasound (US) for suspected acute appendicitis. A fortuitous diagnosis of giant hydronephrosis (GH) was made upon admission, which showed the palpation of a huge poorly delineated abdominal mass that was probably missed at the previous examination by the general physician (GP)...
September 2022: International Journal of Pediatrics & Adolescent Medicine
Ibrahim Al-Ghemlas, Saad Al-Daama, Hawazin Aqueel, Khawar Siddiqui, Hassan El-Solh, Hala Omer, Loloah AlRajeh, Amal Al-Seraihy, Ali Alahmari, Hawazen AlSaedi, Awatif AlAnazi, Mouhab Ayas
Background and objective: Clinical, laboratory and outcome data were reviewed for pediatric patients who were diagnosed with chronic myeloid leukemia (CML) and managed at two tertiary care hospitals in Saudi Arabia, between January 2011 and December 2017 to assess the response to tyrosine kinase inhibitors (TKI) focusing on the monitoring of BCR-ABL fusion gene transcript levels and to look at the overall outcome. Methods: CML patients were identified based on the cytogenetic and molecular results...
September 2022: International Journal of Pediatrics & Adolescent Medicine
Omar Alzomor, Fahad Aljobair, Fawaz Al Kasim, Fauzia Azmet, Sultan Alorini, Yazeed Alshihayb, Yazeed Bahamdan
BACKGROUND: Sickle cell disease (SCD) is a wide prevalence disease worldwide. It has a spectrum of clinical manifestations. However, SCD patients are more susceptible to have a serious bacterial infection (SBI) as compared to other individuals. OBJECTIVE: The main objective of this study was to investigate the prevalence rate of serious bacterial infection (SBI) in febrile children with sickle cell disease (SCD), whose vaccinations are up to date and are on regular penicillin prophylaxis, presented to the emergency department (ED) to assist in the management approach of such patients...
September 2022: International Journal of Pediatrics & Adolescent Medicine
Jan Beute, Alex KleinJan
In the last two decades, improvement on asthma treatment has been merely marginal for both adults and children; inhaled corticosteroids (ICS) combined with β-2-mimetics remain the main therapy [3,4]. "New" therapies are just variations on ICS or, for children, on various other drugs that were allowed for adult asthma patients ( Although currently monoclonal antibodies have been introduced to the field, there is still a large therapeutic burden, given the mortality rate and widespread prevalence of uncontrolled asthma [2]...
June 2022: International Journal of Pediatrics & Adolescent Medicine
Jessie Hawkins, Christy Hires, Elizabeth Dunne, Lindsey Keenan
BACKGROUND: Lavender essential oil and tea tree essential oil have become popular ingredients in personal care and household products in recent decades. Questions regarding the safety of these oils in pediatric populations have been raised, proposing a link between these essential oils and endocrine disruption in children, specifically prepubertal gynecomastia. To date, no epidemiological studies have been conducted to evaluate this proposed link. METHODS: This is a cross sectional study conducted among parents of children in the United States to identify the prevalence of endocrine disruption in children aged 2-15 years old...
June 2022: International Journal of Pediatrics & Adolescent Medicine
Amer Alshengeti, Hatem Alahmadi, Ashwaq Barnawi, Nouf Alfuraydi, Abdulsalam Alawfi, Arwa Al-Ahmadi, Mohammad Sheikh, Amani Almaghthawi, Zahera Alnakhli, Raghad Rasheed, Amany Ibrahim, Ahmed Sobhi, Dayel Al Shahrani, Faisal Kordy
Background and Objective: Coronavirus disease (COVID-19) is milder with favorable outcomes in children than in adults. However, detailed data regarding COVID-19 in children from Saudi Arabia are scarce. This study aimed to describe COVID-19 among children in Al-Madinah, Saudi Arabia. Methods: This retrospective observational study included children <14 years old hospitalized with COVID-19 between May 1, 2020 and July 31, 2020. Clinical data, COVID-19 disease severity, and outcomes were collected...
June 2022: International Journal of Pediatrics & Adolescent Medicine
Jubara Alallah, Loujen Omar Alamoudi, Reham Mohmmed Makki, Aiman Shawli, Alaa T AlHarbi
A full-term male infant born from consanguineous Saudi parents, with one other live child, is suspected to have skeletal dysplasia on a fetal anomaly scan. Clinical findings at birth included short stature, bowed long bone affecting the lower limbs more than the upper limbs, severe joint contractures with restricted movement, failure to thrive, hypertonia, and camptodactyly of the index fingers. During infancy, the baby is noted to have sucking and swallowing difficulties necessitated nasogastric tube feeding, and recurrent respiratory distress episodes with frequent admissions due to respiratory failure required intensive care admission and mechanical ventilation...
June 2022: International Journal of Pediatrics & Adolescent Medicine
Hanaa Banjar, Najlaa AbdulAziz, Jumana Khader, Firas Ghomraoui, AbdulAziz Alansari, Abdulaziz Al-Hoshan, Sara AlKaf, Wajeeh Aldakheel
Background: Internationally, Cystic fibrosis-associated liver disease (CFLD) is considered the third leading cause of death, following lung disease and transplantation complications. Aims: To identify the prevalence of CFLD in cystic fibrosis (CF) patients. Methodology: A retrospective chart review for all patients with CF liver disease from a tertiary care center. Result: A total of 341 CF patients were included. The mean age at the diagnosis of liver disease is 13...
June 2022: International Journal of Pediatrics & Adolescent Medicine
Giovanna Beauchamp, Mary M Barr, Ariana Vergara, Ambika Ashraf, Fernando Bril
Background and objectives: Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) have become public health problems in the pediatric population. However, the relationship between these two conditions is not well understood. The primary objective of this study was to assess whether treatment of hyperglycemia in obese, treatment-naive children with type 2 diabetes (T2DM) was associated with an improvement of surrogate markers of NAFLD. Materials and methods: This retrospective, longitudinal study included 151 obese children with a diagnosis of T2DM (Age: 14 ± 1 years, 72% female children, BMI: 98...
June 2022: International Journal of Pediatrics & Adolescent Medicine
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