journal
Journals Journal of Bone and Joint Infe...

Journal of Bone and Joint Infection

https://read.qxmd.com/read/38127488/frequent-microbiological-profile-changes-are-seen-in-subsequent-revision-hip-and-knee-arthroplasty-for-prosthetic-joint-infection
#1
JOURNAL ARTICLE
Robert A McCulloch, Alex Martin, Bernadette C Young, Benjamin J Kendrick, Abtin Alvand, Lee Jeys, Jonathan Stevenson, Antony J Palmer
A proportion of patients with hip and knee prosthetic joint infection (PJI) undergo multiple revisions with the aim of eradicating infection and improving quality of life. The aim of this study was to describe the microbiology cultured from multiply revised hip and knee replacement procedures to guide antimicrobial therapy at the time of surgery. Patients and methods : Consecutive patients were retrospectively identified from databases at two specialist orthopaedic centres in the United Kingdom between 2011 and 2019...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/38039332/should-treatment-decisions-in-septic-arthritis-of-the-native-hip-joint-be-based-on-the-route-of-infection
#2
JOURNAL ARTICLE
Fred Ruythooren, Stijn Ghijselings, Jordi Cools, Melissa Depypere, Paul De Munter, Willem-Jan Metsemakers, George Vles
Background : Surgical management of septic arthritis (SA) of the hip aims at treating the infection by either preserving, resecting or replacing the joint. In some cases, joint preservation should be attempted, whereas other cases would benefit from immediate joint resection or replacement. Prognostic factors have been proposed to guide decision-making. We hypothesized that most of these factors can be simplified to three subgroups based on the route of infection: contiguous spreading, direct inoculation or hematogenous seeding...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/38039328/antimicrobial-prophylaxis-with-teicoplanin-plus-gentamicin-in-primary-total-joint-arthroplasty
#3
JOURNAL ARTICLE
Tari Azamgarhi, Craig Gerrand, John A Skinner, Alexander Sell, Robert A McCulloch, Simon Warren
Objectives : To compare prosthetic joint infection (PJI) and acute kidney injury (AKI) rates among cohorts before and after changing our hospital's antimicrobial prophylactic regimen from cefuroxime to teicoplanin plus gentamicin. Methods : We retrospectively studied all patients undergoing primary total joint arthroplasty at our hospital 18 months pre- and post-implementation of the change in practice. All deep infections identified during follow-up were assessed against the European Bone and Joint Infection Society (EBJIS) definitions for PJI...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37818255/the-antibiotic-bead-pouch-a-useful-technique-for-temporary-soft-tissue-coverage-infection-prevention-and-therapy-in-trauma-surgery
#4
REVIEW
Markus Rupp, Nike Walter, Dominik Szymski, Christian Taeger, Martin Franz Langer, Volker Alt
Soft tissue defects resulting from trauma and musculoskeletal infections can complicate surgical treatment. Appropriate temporary coverage of these defects is essential to achieve the best outcomes for necessary plastic soft tissue defect reconstruction. The antibiotic bead pouch technique is a reasonable surgical approach for managing temporary soft tissue defects following adequate surgical debridement. This technique involves the use of small diameter antibiotic-loaded bone cement beads to fill the dead space created by debridement...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37780529/a-natural-history-of-untreated-chronic-osteomyelitis-of-the-tibia-over-20-years-with-evolving-squamous-cell-carcinoma-a-case-report
#5
Asanka Wijendra, Alex Ramsden, Martin McNally
Squamous cell carcinoma (SCC) is a rare but potentially life-threatening complication of chronic osteomyelitis. Whilst there have been over 100 cases of chronic osteomyelitis with malignant transformation reported in the literature between 1999 and 2020, this is the first case report to document transformation with 20 years of concordant imaging and clinical review.
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37780528/tuberculous-arthritis-of-native-joints-a-systematic-review-and-european-bone-and-joint-infection-society-workgroup-report
#6
JOURNAL ARTICLE
Leonard C Marais, Luan Nieuwoudt, Adisha Nansook, Aditya Menon, Natividad Benito
Introduction : The aim of this systematic review was to assess the existing published data on the diagnosis and management of tuberculosis (TB) arthritis involving native joints in adults aged 18 years and older. Methods : This study was performed in accordance with the guidelines provided in the Preferred Reporting Items for Systematic reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR). Results : The systematic review of the literature yielded 20 data sources involving 573 patients from nine countries...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37727824/dalbavancin-is-thermally-stable-at-clinically-relevant-temperatures-against-methicillin-sensitive-staphylococcus-aureus
#7
JOURNAL ARTICLE
Aaron K Hoyt, Patrick Lawler, Mathias Bostrom, Alberto V Carli, Ashley E Levack
Introduction : While the rate of orthopaedic infections has remained constant over the years, the burden on healthcare systems continues to rise with an aging population. Local antibiotic delivery via polymethyl methacrylate bone cement is a common adjunct in treating bone and joint infections. Dalbavancin is a novel lipoglycopeptide antibiotic in the same class as vancomycin that has shown efficacy against Gram-positive organisms when used systemically but has not been investigated as a local antibiotic. This study aims to identify whether dalbavancin is thermally stable at the temperatures expected during the polymerization of polymethyl methacrylate cement...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37455814/effectiveness-of-two-stage-revision-with-commercial-polymethylmethacrylate-articulated-hip-spacer-similar-outcomes-against-monomicrobial-and-polymicrobial-hip-periprosthetic-joint-infections
#8
JOURNAL ARTICLE
Leonel Perez Alamino, German Garabano, Joaquín Anibal Rodriguez, Matías Cullari, Hernán Del Sel, Cesar Angel Pesciallo
Background : orthopaedic surgeons still struggle against a devastating complication - periprosthetic joint infection (PJI). A two-stage revision is considered the gold standard for chronic PJI for several authors, with success rates over 90 %. This strategy implies the remotion of the prosthesis and the implantation of an antibiotic-impregnated cement spacer in the joint. The primary objective of this study was to assess the effectiveness of a two-stage revision approach using a commercial prefabricated antibiotic-impregnated cement hip spacer for the treatment of hip PJI regarding monomicrobial and polymicrobial infections...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37187898/-cutibacterium-acnes-in-spine-tissue-characteristics-and-outcomes-of-non-hardware-associated-vertebral-osteomyelitis
#9
JOURNAL ARTICLE
Matteo Passerini, Julian Maamari, Don Bambino Geno Tai, Robin Patel, Aaron J Tande, Zelalem Temesgen, Elie F Berbari
Cutibacterium acnes isolation from spine tissue can be challenging because the organism can represent a contaminant. There is a paucity of data regarding the role of C. acnes in non-hardware-associated vertebral osteomyelitis (VO). Herein we evaluate the clinical and microbiological characteristics, treatment, and outcome of patients with C. acnes VO. Data were retrospectively collected from adults with a positive spine culture for C. acnes at Mayo Clinic, Rochester (MN), from 2011 to 2021. Patients with spinal hardware and polymicrobial infections were excluded...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37123503/the-efficacy-of-antibiotic-impregnated-calcium-sulfate-aics-in-the-treatment-of-infected-non-union-and-fracture-related-infection-a-systematic-review
#10
JOURNAL ARTICLE
Connor C Jacob, Jad H Daw, Juan Santiago-Torres
Background : the treatment of infected non-union to allow for bony healing following orthopedic surgery remains a challenge. Antibiotic-impregnated calcium sulfate (AICS) is an effective vehicle for antibiotic delivery, but its efficacy in treating infected non-union in the setting of trauma and fracture remains unclear. Methods : this systematic review analyses nine studies from 2002 to 2022 that investigated AICS as a local antibiotic delivery system for cases of fracture-related infection and infected non-union...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37123502/murine-models-of-orthopedic-infection-featuring-staphylococcus-aureus-biofilm
#11
JOURNAL ARTICLE
Aiken Dao, Alexandra K O'Donohue, Emily R Vasiljevski, Justin D Bobyn, David G Little, Aaron Schindeler
Introduction : Osteomyelitis remains a major clinical challenge. Many published rodent fracture infection models are costly compared with murine models for rapid screening and proof-of-concept studies. We aimed to develop a dependable and cost-effective murine bone infection model that mimics bacterial bone infections associated with biofilm and metal implants. Methods : Tibial drilled hole (TDH) and needle insertion surgery (NIS) infection models were compared in C57BL/6 mice (female, <mml:math xmlns:mml="https://www...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37123501/sex-specific-analysis-of-clinical-features-and-outcomes-in-staphylococcal-periprosthetic-joint-infections-managed-with-two-stage-exchange-arthroplasty
#12
JOURNAL ARTICLE
Eibhlin Higgins, Don Bambino Geno Tai, Brian Lahr, Gina A Suh, Elie F Berbari, Kevin I Perry, Matthew P Abdel, Aaron J Tande
Background : Differences in susceptibility and response to infection between males and females are well established. Despite this, sex-specific analyses are under-reported in the medical literature, and there is a paucity of literature looking at differences between male and female patients with periprosthetic joint infection (PJI). Whether there are sex-specific differences in presentation, treatment tolerability, and outcomes in PJI has not been widely evaluated. Methods : We undertook a retrospective case-matched analysis of patients with staphylococcal PJI managed with two-stage exchange arthroplasty...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37123500/outcomes-in-patients-with-clinically-suspected-pedal-osteomyelitis-based-on-bone-marrow-signal-pattern-on-mri
#13
JOURNAL ARTICLE
Christin A Tiegs-Heiden, Tanner C Anderson, Mark S Collins, Matthew P Johnson, Douglas R Osmon, Doris E Wenger
Objective : confluent T1 hypointense marrow signal is widely accepted to represent osteomyelitis on MRI. Some authors have suggested that non-confluent bone marrow signal abnormality should be considered early osteomyelitis. The purpose of this study was to address this issue by comparing the rate of osteomyelitis and amputation based on T1 marrow signal characteristics. Materials and methods : a total of 112 patients who underwent MRI of the foot for the evaluation of possible osteomyelitis were included. Patients were assigned to confluent T1 hypointense, reticulated T1 hypointense, and normal bone marrow signal groups...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37123499/diagnosis-of-fracture-related-infection-in-patients-without-clinical-confirmatory-criteria-an-international-retrospective-cohort-study
#14
JOURNAL ARTICLE
Niels Vanvelk, Esther M M Van Lieshout, Jolien Onsea, Jonathan Sliepen, Geertje Govaert, Frank F A IJpma, Melissa Depypere, Jamie Ferguson, Martin McNally, William T Obremskey, Charalampos Zalavras, Michael H J Verhofstad, Willem-Jan Metsemakers
Background : fracture-related infection (FRI) remains a serious complication in orthopedic trauma. To standardize daily clinical practice, a consensus definition was established, based on confirmatory and suggestive criteria. In the presence of clinical confirmatory criteria, the diagnosis of an FRI is evident, and treatment can be started. However, if these criteria are absent, the decision to surgically collect deep tissue cultures can only be based on suggestive criteria. The primary study aim was to characterize the subpopulation of FRI patients presenting without clinical confirmatory criteria (fistula, sinus, wound breakdown, purulent wound drainage or presence of pus during surgery)...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37032978/evaluating-the-utility-of-inflammatory-markers-in-the-diagnosis-of-soft-tissue-abscesses-of-the-forearm-and-hand
#15
JOURNAL ARTICLE
Sarah R Blumenthal, Adnan N Cheema, Steven E Zhang, Benjamin L Gray, Nikolas H Kazmers
Upper extremity abscesses frequently present to the acute care setting with inconclusive physical examination and imaging findings. We sought to investigate the diagnostic accuracy of inflammatory markers including white blood cell (WBC) count, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP). A retrospective cohort study was performed to identify subjects <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mo>≥</mml:mo> <mml:mn>18</mml:mn></mml:mrow> </mml:math>  years treated with surgical debridement of upper extremity abscesses at our institution between January 2012 and December 2015...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/37032977/simple-and-inexpensive-synovial-fluid-biomarkers-for-the-diagnosis-of-prosthetic-joint-infection-according-to-the-new-ebjis-definition
#16
JOURNAL ARTICLE
Sara Elisa Diniz, Ana Ribau, André Vinha, José Carlos Oliveira, Miguel Araújo Abreu, Ricardo Sousa
Introduction : diagnosis of periprosthetic joint infection (PJI) is challenging, as no single test has absolute accuracy. The purpose of this study was to assess the utility of different simple synovial biomarkers in the diagnosis of PJI as defined by the European Bone and Joint Infection Society (EBJIS). Methods : we retrospectively identified all patients undergoing revision hip or knee arthroplasty from 2013 to 2019 on our prospectively maintained database. Only patients with minimum required infection diagnostic workup were included in the study...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/36938482/wound-drainage-after-arthroplasty-and-prediction-of-acute-prosthetic-joint-infection-prospective-data-from-a-multicentre-cohort-study-using-a-telemonitoring-app
#17
JOURNAL ARTICLE
Henk Scheper, Rachid Mahdad, Brenda Elzer, Claudia Löwik, Wierd Zijlstra, Taco Gosens, Joris C T van der Lugt, Robert J P van der Wal, Rudolf W Poolman, Matthijs P Somford, Paul C Jutte, Pieter K Bos, Richard E Zwaan, Rob G H H Nelissen, Leo G Visser, Mark G J de Boer, The Wound Care App Study Group
Background : Differentiation between uncomplicated and complicated postoperative wound drainage after arthroplasty is crucial to prevent unnecessary reoperation. Prospective data about the duration and amount of postoperative wound drainage in patients with and without prosthetic joint infection (PJI) are currently absent. Methods : A multicentre cohort study was conducted to assess the duration and amount of wound drainage in patients after arthroplasty. During 30 postoperative days after arthroplasty, patients recorded their wound status in a previously developed wound care app and graded the amount of wound drainage on a 5-point scale...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/36756306/first-evaluation-of-a-commercial-multiplex-pcr-panel-for-rapid-detection-of-pathogens-associated-with-acute-joint-infections
#18
JOURNAL ARTICLE
Jorrit Willem Adriaan Schoenmakers, Rosanne de Boer, Lilli Gard, Greetje Anna Kampinga, Marleen van Oosten, Jan Maarten van Dijl, Paulus Christiaan Jutte, Marjan Wouthuyzen-Bakker
Background : prompt recognition and identification of the causative microorganism in acute septic arthritis of native and prosthetic joints is vital to increase the chances of successful treatment. The aim of this study was to independently assess the diagnostic accuracy of the multiplex BIOFIRE® Joint Infection (JI) Panel (investigational use only) in synovial fluid for rapid diagnosis. Methods : synovial fluid samples were collected at the University Medical Center Groningen from patients who had a clinical suspicion of a native septic arthritis, early acute (post-operative, within 3 months after arthroplasty) periprosthetic joint infection (PJI) or late acute (hematogenous, <mml:math xmlns:mml="https://www...
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/36756305/chronic-q-fever-presenting-as-bilateral-extensor-tenosynovitis-a-case-report-and-review-of-the-literature
#19
Kareme D Alder, Anthony P Fiegen, Matthew M Rode, Don Bambino Geno Tai, Gina A Suh, Abinash Virk, Nicholas Pulos
Musculoskeletal manifestations of Coxiella burnetii are rare. We describe an elderly, immunosuppressed male with bilateral Coxiella burnetii extensor tenosynovitis treated with incision and debridement and chronic doxycycline and hydroxychloroquine. Additionally, disease etiology, risk factors, pertinent features of the history, testing modalities, and treatment strategies of musculoskeletal Q fever are reviewed.
2023: Journal of Bone and Joint Infection
https://read.qxmd.com/read/36756304/guideline-for-management-of-septic-arthritis-in-native-joints-sanjo
#20
JOURNAL ARTICLE
Christen Ravn, Jeroen Neyt, Natividad Benito, Miguel Araújo Abreu, Yvonne Achermann, Svetlana Bozhkova, Liselotte Coorevits, Matteo Carlo Ferrari, Karianne Wiger Gammelsrud, Ulf-Joachim Gerlach, Efthymia Giannitsioti, Martin Gottliebsen, Nis Pedersen Jørgensen, Tomislav Madjarevic, Leonard Marais, Aditya Menon, Dirk Jan Moojen, Markus Pääkkönen, Marko Pokorn, Daniel Pérez-Prieto, Nora Renz, Jesús Saavedra-Lozano, Marta Sabater-Martos, Parham Sendi, Staffan Tevell, Charles Vogely, Alex Soriano, The Sanjo Guideline Group
This clinical guideline is intended for use by orthopedic surgeons and physicians who care for patients with possible or documented septic arthritis of a native joint (SANJO). It includes evidence and opinion-based recommendations for the diagnosis and management of patients with SANJO.
2023: Journal of Bone and Joint Infection
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