Xiaofeng Deng, Haoran Xu, Xiaoxia Hao, Jiawei Liu, Xingru Shang, Tao Xu
Osteoarthritis (OA) is a chronic degenerative disease, which can cause a series of symptoms including pain and functional limitation, thus severely decreasing quality of life. OA pathogenesis can be categorized into four levels, including risk factors, potential mechanisms, intraarticular degeneration phenotype, and substantive histological changes. Moderate exercise can alleviate OA at all levels of pathogenesis, while excessive exercise may have adverse effects. Based on rat-related original research, the parameters of moderate exercise and the effect of improving osteoarthritis have been comprehensively summarized...
March 14, 2023: EFORT Open Reviews