Xuemei Liu, Jie Min, Bin She, Yan Chen, Jun Li, Lei Huang, Ju Chen, Ai Luo, Mei Yang, Ting Li, Yanqing Wu, Daohong Chen, Hongli Zhong, Wei Liu, Bing Mao, Hongli Jiang
BACKGROUND: Binafuxi granules are a traditional Uighur medicine (TUM) for treating the common cold with fever. However, high-quality clinical studies supporting its efficacy and safety are lacking. METHODS: In this multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial, patients with common cold and fever were randomly assigned to a high-dose group, low-dose group, and placebo group in a 1:1:1 ratio. Outcomes were time to fever relief, time to fever clearance, proportion of afebrile patients, time to symptom disappearance, rate of symptom disappearance, effective rate, emergency drug usage and safety assessment...
September 2023: Integrative Medicine Research