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Integrative Medicine Research

Seungwon Kwon, Chul Jin, Ki-Ho Cho
Oreongsan (ORS), which is composed of Polyporus, Alismatis Rhizoma, Atractylodis Rhizoma, Poria (Hoelen), and Cinnamomi Cortex Spissus, has been used as treatment in patients with various symptoms such as thirst, diminished urination, edema, hangover, and diarrhea. ORS is the representative prescription of the ( isu ) effect (translated from Korean as "induce diuresis"), which traditionally means the effect of controlling the water balance. Advancement of modern science has enabled the determination of the action mechanism of herbal medicine complexes...
March 2019: Integrative Medicine Research
Xinbing Sui, Yong Guo, Wei Ni, Haiyan Jin, Haoming Lin, Tian Xie
Background: Traditional Chinese medicine (TCM) syndromes ( ZHENG in Chinese) constitute the basis of understanding the disorders of patients and guiding the use of the Chinese herbs. Colorectal cancer is divided into various subtypes mainly according to the ZHENG identification. Objective: We aimed to determine the molecular basis underlying Pi - Xu (spleen deficiency) and Shi - Re (dampness-heat) ZHENG that are commonly found in colorectal cancer patients. Methods: About 80 colorectal cancer patients, including 47 Pi - Xu ZHENG and 33 Shi - Re ZHENG were enrolled...
March 2019: Integrative Medicine Research
Sujeong Mun, Siwoo Lee, Kihyun Park, Sang-Jae Lee, Byung-Hee Koh, Younghwa Baek
Background: Complementary and alternative medicine treatment for insomnia has been sought due to the possible adverse effects of conventional pharmacotherapies. We performed a preliminary evaluation of the feasibility of using, and of the effect of a herbal tea (HT002), based on Traditional East Asian Medicine, in mild-to-moderate insomnia. Methods: Patients ( n  = 40) with mild-to-moderate insomnia were randomized to the HT002 ( n  = 20) or waitlist ( n  = 20) groups...
March 2019: Integrative Medicine Research
Kailey Snyder, Danae Dinkel
Background: The low incidence of exercise during pregnancy and the high rates of prenatal depression indicate more opportunities are needed for mothers to engage in exercise and obtain health-related support and education. MAPS (mental & physical support) was developed to support mothers' psychological and physical health during pregnancy. MAPS consisted of physical activity classes 2×/week followed by either a speaker or group discussion regarding a parenting or health-related topic...
March 2019: Integrative Medicine Research
Kyung-Min Shin, Ji-Eun Park, Tae-Han Yook, Jong-Uk Kim, Ojin Kwon, Sun-Mi Choi
Background: Prehypertension and hypertension are associated with cardiovascular disease, ischemic heart disease, and stroke morbidity. The purpose of this study is to evaluate the effectiveness and safety of moxibustion in patients with prehypertension or hypertension. Methods: Forty-five subjects with prehypertension or stage I hypertension were randomized into three groups: moxibustion treatment group A (2 sessions/week for 4 weeks), moxibustion treatment group B (3 sessions/week for 4 weeks), and control group (nontreated group)...
March 2019: Integrative medicine research
O Sang Kwon, So Min Lee, Kwang-Ho Choi, Young Jun Lee, Jee Yeon Jung
Tic disorder is characterized as sudden, non-rhythmic, involuntary and repetitive movement or vocalization, and its onset occurs mainly in childhood or adolescence. The development of medication has been limited because of a lack of understanding of tic mechanisms, and behavioral treatment is recommended as a first-line treatment. In this case report, we observed three cases in which tic disorder or Tourette syndrome was treated with intraoral orthopedic treatment (FCST) combined with acupuncture and an herbal formula and was assessed using the Yale Global Tic Severity Scale (YGTSS), a visual analog scale (VAS) and video analysis...
December 2018: Integrative Medicine Research
Ki-Shuk Shim, Jin Yeul Ma
Background: The leaf of Pinus densiflora known as pine needles has been used to treat vascular disease, gastrointestinal diseases, and urinary diseases in traditional medicine. We evaluated anti-osteoporotic effect of water extract of Pinus densiflora (WEPN) on acute bone loss and osteoclastogenesis induced by receptor activator for nuclear factor-κB ligand (RANKL). Methods: After oral administration of WEPN (0.25 g/kg) for 5 days, femora were collected, and bone parameter [trabecular bone volume/tissue volume (BV/TV), trabecular thickness (Tb...
December 2018: Integrative Medicine Research
Himanshu Sharma, Prerna Chauhan, Surender Singh
Background: Cinnamomum cassia iswidely used as a traditional medicinal plant for the treatment of rheumatoid arthritis. Objective: The present study aimed to assess the anti-arthritic activity of C. cassia bark hydroalcoholic extract (CCHE) in different arthritic animal models. Methods: In formaldehyde model, sub-plantar administration of 0.1 ml of formaldehyde (2% v/v) into the right hind paws of Wistar albino rats on days 0 and 3. The rats were divided into six groups as follows: normal control, disease control, indomethacin group (3 mg/kg, p...
December 2018: Integrative Medicine Research
Humaira Bano, Nasreen Jahan, Shaikh Ajij Ahmed Makbul, B N Kumar, Sadique Husain, Atiya Sayed
Background: To investigate the antilithiatic effect of hydroalcoholic extract of Kabab Chini ( Piper cubeba L.) fruit in male Sprague Dawley rats. Methods: Rats were divided into six groups of six each. Group I received regular rat food and drinking water ad libitum . Groups II to VI were administered with ethylene glycol (EG) 0.75% (V/V) and ammonium chloride (AC) 1% (W/V) in drinking water for 7 days to induce urolithiasis. From 8th day Group I received 1 mL of 5% gum acacia...
December 2018: Integrative medicine research
Soo-Wang Hyun, Junghyun Kim, Kyuhyung Jo, Jin Sook Kim, Chan-Sik Kim
Background: Diabetes mellitus (DM) is one of the most common diseases found across the world. Aster koraiensis extract (AKE) has a protective effect on diabetic complications such as diabetic retinopathy. However, the effects of AKE on hyperglycemia-linked impairment of wound healing during DM have not been elucidated. In this study, we investigated the effects of AKE on delayed wound healing induced by DM. Methods: DM was induced by intraperitoneal administration of streptozotocin (STZ; 75 mg/kg) to Sprague Dawley (SD) rats...
December 2018: Integrative Medicine Research
Tae Yeong Kim, Sung Eun You, You Sun Ko
Background: The purpose of this study was to investigate differences in obesity factors according to Sasang constitutional types and quality of sleep among Korean female college students. Methods: Surveys using Sasang-types questionnaires(QSCCⅡ) and quality of sleep questionnaires(PSQI; Pittsburgh Sleep Quality Index) were conducted with 339 Korean female college students. Additionally, obesity factors, including weight, fat mass, fat percent, abdominal fat percent, body mass index (BMI) and obesity rates were measured...
December 2018: Integrative Medicine Research
Hye-Yoon Lee, Young-Ju Yun, Sun-Ae Yu, Yo-Han Park, Byung-Wook Park, Bu-Young Kim, Man-Suk Hwang
Background: Traditional Korean medicine (TKM) is widely used to treat children with cerebral palsy (CP) in Korea; however, studies investigating factors that influence the use of TKM are scarce. Thus, we investigated the clinical factors that might influence the use of TKM. Methods: A population-based, cross-sectional, multicenter survey was performed from August 2014 to May 2016. The history of TKM use, type and severity of CP, current treatment characteristics, presence of accompanying disabilities or other health problems not directly related to CP, and monthly cost for the treatment of CP were surveyed...
December 2018: Integrative Medicine Research
Maryam Ranjbar, Ali Firoozabadi, Alireza Salehi, Zahra Ghorbanifar, Mohammad M Zarshenas, Khosro Sadeghniiat-Haghighi, Hossein Rezaeizadeh
Background: Insomnia is a prevalent disorder leading to psychological problems such as anxiety and depression. Methods: This study investigates the effect of a combination of herbs ( Melissa officinalis L. and Nepeta menthoides Boiss. & Buhse) on anxiety and depression for insomniacs and on insomnia severity. This study is a double-blind randomized placebo-controlled clinical trial. A total number of 67 participants met the inclusion criteria who were diagnosed as cases of insomnia...
December 2018: Integrative Medicine Research
Nik Shah Hizan, Nor Hasnina Mohd Hassan, Juhara Haron, Murtala Bello Abubakar, Nik Munirah Nik Mahdi, Siew Hua Gan
Background: To investigate whether the combination of anastrozole and Tualang honey (T honey) influences background parenchymal enhancement (BPE) in breast magnetic resonance imaging (MRI) of postmenopausal women with breast cancer. Methods: A total of 30 patients were recruited and randomly divided into control (anastrozole 1 mg daily) and intervention (anastrozole 1 mg + T honey 20 g daily). The BPE of the contralateral breast before and six months following treatment was compared using the sign test...
December 2018: Integrative Medicine Research
Mohamed K M Khalil, Sulaiman Al-Eidi, Meshary Al-Qaed, Saud AlSanad
Saudi Arabia is witnessing a healthcare transformation to face the challenges of the increased burden of noncommunicable diseases and to maintain the quality of healthcare services. However, in Saudi Arabia, where low back and neck pain, depressive disorders, migraine, diabetes, and anxiety disorders cause the most disability, a broader way of integrative health approach is needed to foster healthy lives and promote well-being for all ages. In the presence of the advanced modern medicine healthcare system in Saudi Arabia, the traditional medicine healing system is being used by a substantial proportion of Saudis but like a shadow healthcare system...
December 2018: Integrative Medicine Research
A G F Najeeya, Arshiya Sultana
Background: It is not only to evaluate the efficacy and safety of mace (Arils of Myristica fragrans Houtt) but also to compare pelvic floor muscle training vs. pelvic floor muscle training (PFMT) for improving symptoms and health-related quality of life (HRQoL) of woman with mixed urinary incontinence (MUI). Methods: A prospective, single-blind randomized controlled study was conducted. Patients ( n  = 60) were randomly allocated (1:1) to receive either mace powder or placebo (1...
December 2018: Integrative Medicine Research
Chae-Hak Lim, Jeong-Eun Yoo
Uterine myoma is a common benign tumor. When the symptoms are not severe, patients are often suggested to wait for menopause without treatment. If the size becomes too large or the symptoms get worse, the patient will receive surgery or hormone therapy. If a patient does not receive surgery or hormone therapy because of the waiting period, traditional Korean medicine (TKM) treatment can be applied. This is a case of a 47-year-old woman who was diagnosed with thyroid cancer and uterine myoma. She was diagnosed with thyroid cancer in 2012 and uterine myoma in 2013...
December 2018: Integrative Medicine Research
Hae-Won Kim, Jeong-Eun Yoo
Endometriosis is a common benign gynecologic tumor, and it can destroy a patient's life. Surgery and hormone therapy are established therapies for endometriosis. However, there are many cases of recurrent endometriosis after conventional therapies. This report presents a case of a patient who has repetitive recurrence of endometriosis after laparoscopic excision and hormone therapy. A 32-years-old female patient first had laparoscopic surgery to remove endometriosis in 2011. The disease recurred two more times after the first excision...
September 2018: Integrative Medicine Research
Jung Eun-Sun, Lee Jun-Hwan, Kim Hyun-Tae, Park Sang-Soo, Kim Ji-Eun, Cha Ji-Yoon, Seol In-Chan, Choi Young-Eun, Ho-Ryong Yoo
Background: Currently, there is no clearly established therapy to treat mild cognitive impairment (MCI); consequently, alternative therapies, such as acupuncture, have been attempted. In many clinical studies, the potential benefits of acupuncture for cognitive improvement have been identified in clinical outcomes; however, the mechanism remains unclear. Accordingly, this study aims to investigate the therapeutic mechanism of acupuncture therapy using functional near-infrared spectroscopy and its feasibility in treating individuals with impaired cognitive function...
September 2018: Integrative Medicine Research
Joshua Z Goldenberg, Amie Steel, Andrew Day, Christina Yap, Ryan Bradley, Kieran Cooley
Background: Irritable bowel syndrome (IBS) is a common functional bowel disorder with a worldwide prevalence estimated between 10% and 20%. It has a significant impact on quality of life and societal expense. While there are pharmaceutical options available, few can be reliably recommended. Many IBS sufferers turn to complementary and alternative medicine including naturopathy. Naturopathic approaches to IBS are poorly studied to date. Methods: We aim to describe naturopathic approaches to IBS as well as establish pilot data on before and after changes in validated IBS instruments...
September 2018: Integrative Medicine Research
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