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Translational Gastroenterology and Hepatology

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https://read.qxmd.com/read/30701216/alcohol-related-liver-disease-do-weather-and-daylight-level-matter-or-is-there-a-paradoxical-good-side-of-global-warming
#1
EDITORIAL
Nathalie Ganne-Carrié
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30701215/surgical-treatment-of-gastrointestinal-stromal-tumours-combined-with-imatinib-treatment-a-retrospective-cohort-analysis
#2
Robert Bachmann, Jens Strohäker, Julian Kraume, Alfred Königsrainer, Ruth Ladurner
Background: Targeted therapies changed the treatment concepts of gastrointestinal stromal tumours significantly. As only possibility to cure surgical resection is the cornerstone of therapy. Thus it is necessary to find out which patients will benefit most regarding modality (neo- or adjuvant) and duration of chemotherapy. Methods: In a retrospective cohort analysis the medical records of all consecutive patients treated in the department of general and visceral surgery of the university hospital Tübingen between 2004 and 2015 were investigated...
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30701214/understanding-and-quantifying-the-immune-microenvironment-in-hepatocellular-carcinoma
#3
EDITORIAL
Juan C Osorio, James J Harding
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30701213/higher-rate-of-colon-polyp-detection-aided-by-an-artificial-intelligent-software
#4
EDITORIAL
Masaaki Iwatsuki, Kazuto Harada, Hideo Baba, Jaffer A Ajani
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30701212/counting-on-quality-in-endoscopy-globally-all-that-matters-now
#5
COMMENT
Krish Ragunath
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30701211/refining-surgical-therapy-of-liver-cancer-in-cirrhosis-etiology-makes-the-difference
#6
EDITORIAL
Massimo Colombo, Ana Lleo
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30701210/liver-transplantation-for-hepatocellular-carcinoma-alpha-fetoprotein-should-be-included-in-selection-criteria
#7
EDITORIAL
Hans-Christian Pommergaard
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30701209/endoscopic-surveillance-or-ablation-for-barrett-s-esophagus
#8
REVIEW
John M Inadomi, Nina Saxena
The incidence of esophageal adenocarcinoma (EAC) is rising and the only known precursor of this disease is Barrett's esophagus (BE). EAC mortality remains high, prompting strategies to screen individuals with gastroesophageal reflux disease (GERD) symptoms to identify BE and conduct surveillance in order to detect neoplasia at a stage that is amenable to cure. The effectiveness of endoscopic eradication therapy has been improving with reduced harms, yet it is unclear which patients will benefit from this procedure...
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30701208/does-anti-reflux-surgery-disrupt-the-pathway-of-barrett-s-esophagus-progression-to-cancer
#9
REVIEW
Sebastian F Schoppmann, Ivan Kristo, Martin Riegler
In patients with Barrett's esophagus (BE), anti-reflux surgery aims to sustainable control reflux symptoms and heal reflux induced esophageal mucosal inflammation and prevent progression of BE to adenocarcinoma. There is growing evidence that beside gastric acid, bile salts in refluxed duodenal juice are responsible for the development and progression of BE. However, the pathogenesis of BE progression and the metaplasia-dysplasia-carcinoma sequence of the adenocarcinoma of the esophagus (EAC) is multifactorial and occurs over long natural time course...
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30701207/shuji-ogino-a-critical-mass-of-pathological-epidemiologists-is-needed-for-transdisciplinary-studies
#10
Brad Li
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30603735/new-trends-and-perspectives-in-hepatobiliary-surgery-preface
#11
Alessandro Vitale, Quirino Lai
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30603734/is-it-time-to-define-complete-mesocolic-excision-as-a-standardized-colon-cancer-surgery
#12
COMMENT
Chao Wang, Zhidong Gao, Zhanlong Shen, Kewei Jiang, Shan Wang, Yingjiang Ye
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30603733/traditional-chinese-medicine-to-the-rescue-of-allopathic-medicine-in-the-co-adjuvant-treatment-of-hepatocellular-carcinoma
#13
EDITORIAL
Jordan Sparkman, Ruben Hernaez, Hashem B El-Serag
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30603732/histology-driven-systemic-therapy-of-liposarcoma-ready-for-prime-time
#14
REVIEW
Sara Jo Grethlein
Liposarcomas are a subtype of soft tissue sarcomas arising from adipocytes. These mesenchymal tumors have been sub classified into well differentiated liposarcoma (WDLPS), dedifferentiated liposarcoma (DDLPS), myxoid liposarcoma (MLPS) and pleomorphic liposarcoma (PLPS). This article reviews what has been reported regarding the responsiveness of these sarcoma subtypes to traditional and newly developed systemic therapies. The evolution of molecular targets for therapeutic intervention within the distinct histologies is discussed, along with, available evidence regarding the efficacy of novel target directed therapies...
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30603731/the-use-of-indocyanine-green-imaging-technique-in-patient-with-hepatocellular-carcinoma
#15
REVIEW
Shih-Wei Huang, Jing-Jim Ou, Hon Phin Wong
Near-infrared indocyanine green (ICG) fluorescence application in liver cancer surgery have been reported in the literature since 2008. To date, most reports emphasized not only to the safety, feasibility and reproducibility, but also the potential benefits of its clinical applications in term of demarcating segmentation for an anatomical resection, tumor identification to achieve tumor free resection margin, detection of small unidentifiable subcapsular nodules as well as extrahepatic metastatic lesions, and fluorescence cholangiography...
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30603730/solitary-fibrous-tumor
#16
REVIEW
Brian Davanzo, Robert E Emerson, Megan Lisy, Leonidas G Koniaris, Joshua K Kays
Solitary fibrous tumor (SFT) is a rare tumor of mesenchymal origin that account for less than 2% of all soft tissue masses. Initially identified in the pleura, SFT has been identified in multiple anatomic locations and can arise anywhere in the body. The varying histologic features along with non-specific means of identification have led SFT to be associated with several different names. Over the last several decades, sustained advances through research and technology have led to more reliable methods for differentiating this distinct soft tissue tumor...
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30603729/endoscopic-ultrasound-guided-gastrojejunostomy
#17
REVIEW
Enad Dawod, Jose M Nieto
Endoscopic ultrasound guided gastrojejunostomy (EUS-GJ) has been mostly employed in the treatment of benign and malignant gastric outlet obstruction (GOO). Additionally, EUS-GJ has been used in the treatment of afferent loop syndrome. EUS-GJ has been employed in the treatment of benign and malignant GOO. EUS-GJ has also been used in the treatment of afferent loop syndrome. EUS-GJ involves obtaining access to the jejunum endoscopically and sonographically from the stomach, using a biflanged lumen apposing metal stent (LAMS)...
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30603728/approach-to-wild-type-gastrointestinal-stromal-tumors
#18
REVIEW
Joshua K Kays, Jeffrey D Sohn, Bradford J Kim, Katherine Goze, Leonidas G Koniaris
Gastrointestinal stromal tumors (GISTs) arise from the intestinal pacemaker cells of Cajal. Wild-type gastrointestinal stromal tumors (WT-GIST) are a unique and uncommon subtype of GISTs that lack activating mutations in the tyrosine kinase c-KIT or platelet derived growth factor receptor alpha (PDGFRA) receptors. The lack of these growth-stimulating mutations renders tyrosine kinase receptor inhibitors, such as imatinib mesylate, relatively ineffective against these tumors. WT-GIST arises most commonly due to underlying alternate proliferative signals associated with germ-line, genetic mutations...
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30603727/translational-medical-research-and-liver-transplantation-systematic-review
#19
REVIEW
Lucas Souto Nacif, Vera Kim, Flavio Galvão, Suzane Kioko Ono, Rafael Soares Pinheiro, Flair José Carrilho, Luiz Carneiro D'Albuquerque
Translational medicine has become a priority, but there is still a big difference between the arrival of new treatments and investment. Basic science should not be neglected because the translation from basic research is not sustained in the absence of basic research. The purpose of this literature review was to analyze the translational medicine in the liver transplant field: liver ischemia-reperfusion injury (IRI), immunosuppression, clinical and surgical complications, small-for-size syndrome (SFSS), rejection, and ongoing innovations (liver machine, liver preservation, artificial livers, and regenerative medicine)...
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30603726/a-review-of-endoscopic-ultrasound-guided-endoscopic-retrograde-cholangiopancreatography-techniques-in-patients-with-surgically-altered-anatomy
#20
REVIEW
Rucha Mehta Shah, Paul Tarnasky, Prashant Kedia
Endoscopic retrograde cholangiopancreatography (ERCP) is the primary therapeutic intervention for pancreaticobiliary duct diseases. Surgically altered anatomy (SAA) makes performing successful ERCP challenging. In this review article the concept of endoscopic ultrasound guided pancreaticobiliary drainage (EUS-PBD) in cases of SAA where conventional ERCP fails or is not possible will be reviewed. EUS-PBD serves as an emerging and promising alternative for pancreaticobiliary therapy in the hands of skilled endoscopists compared to conventional therapies such as device-assisted ERCP, laparoscopic-assisted ERCP, or percutaneous drainage...
2018: Translational Gastroenterology and Hepatology
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