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Northern Clinics of Istanbul

Suleyman Celebi, Seyithan Ozaydin, Esra Polat, Cemile Basdas, Elmas Reyhan Alim, Serdar Sander
OBJECTIVE: The aim of this study was to review the management of pediatric cases of vitelline duct pathology (VDP) detected surgically or incidentally during the neonatal period and the outcomes. METHODS: The data of newborns who were symptomatic and underwent VDP resection or who were incidentally diagnosed with VDP at a single institution between 1985 and 2015 were retrospectively analyzed in terms of age, sex, clinical features, treatment, perioperative findings, ectopic tissue pathology, and postoperative follow-up information...
September 2018: Northern Clinics of Istanbul
Yigit Canga, Tolga Sinan Guvenc, Ali Nazmi Calik, Mehmet Baran Karatas, Tahir Bezgin, Tolga Onuk, Ahmet Okan Uzun, Veysel Ozan Tanik, Baris Gungor, Osman Bolca
OBJECTIVE: Pathological studies have suggested that local inflammation, particularly eosinophilic infiltration of the adventitia, could be related to nonatherosclerotic spontaneous coronary artery dissection (NA-SCAD). However, the role of systemic inflammation in the pathogenesis of NA-SCAD remains unknown. Our aim was to investigate systemic inflammatory activation in patients with an acute coronary syndrome (ACS) secondary to NA-SCAD. METHODS: The institutional electronic medical database was reviewed, and 22 patients with NA-SCAD-ACS were identified after the review...
September 2018: Northern Clinics of Istanbul
Cengiz Yuksel, Seyit Ankarali, Nehir Aslan Yuksel
The strong magnetic field properties of magnets have led to their use in many modern technologies, as well as in the fields of medicine and dentistry. Neodymium magnets are a powerful type of magnet that has been the subject of recent research. This review provides a brief explanation of the definition, history, and characteristics of rare earth magnets. In addition, a broad overview of results obtained in studies performed to date on the effects of magnets, and neodymium magnets in particular, on body systems, tissues, organs, diseases, and treatment is provided...
September 2018: Northern Clinics of Istanbul
Aziz Sener, Alper Sahbaz, Leyla Turker Sener, Merva Soluk Tekkesin, Bulent Kaya
OBJECTIVE: In this study, the effect of mesalazine was studied on TNF alpha IL-1 beta, IL-6, and C-reactive protein (CRP) levels and inflammatory changes in rat lungs with experimental peritonitis. METHODS: In total, 24 male Sprague-Dawley rats weighing 250-280 g were used in the study.The rats were divided into three groups based on no irrigation or irrigation with isotonic solution or mesalazine. Secondary peritonitis was generated by cecum penetrations. Group I, no irrigation was given after the development of peritonitis; Group II, irrigation was performed using isotonic solution 24 h after the development of peritonitis...
September 2018: Northern Clinics of Istanbul
Adil Baskiran, Emrah Sahin, Nese Karadag, Tevfik Tolga Sahin, Bora Barut, Dincer Ozgor, Abuzer Dirican
OBJECTIVE: Gallbladder cancer (GBC) is a rare clinical entity that has a poor prognosis. Radical resection with meticulous lymph node dissection is the only treatment option. The aim of the present study is to evaluate the efficacy of radical resection for GBC in the early postoperative period with the viewpoint of clinicopathological correlation. METHODS: Patients (n=24) who underwent radical resection with lymph node dissection for GBC between 2015 and 2017 were included...
September 2018: Northern Clinics of Istanbul
Alper Ozcan, Ceyda Arslanoglu, Ekrem Unal, Turkan Patiroglu, Mehmet Akif Ozdemir, Kemal Deniz, Serdal Sadet Ozcan, Musa Karakukcu
OBJECTIVE: Solid pseudopapillary tumor (SPT) of the pancreas is an extremely rare primary tumor in the pediatric age group. It has a low malignant potential and the prognosis is good if radical resection of the tumor is performed. Local recurrence and distant metastasis has only rarely been reported following incomplete resection. METHODS: A retrospective review of the medical records of 6 patients diagnosed as SPT according to a histopathological examination at the Children's Hospital of Erciyes University School of Medicine between 2010 and 2017 was performed...
September 2018: Northern Clinics of Istanbul
Cemal Kocaaslan, Mustafa Aldag, Tamer Kehlibar, Mehmet Yilmaz, Ebuzer Aydin, Bulend Ketenci
Endovascular aneurysm repair (EVAR) has been widely accepted as a safe and effective treatment for abdominal aortic aneurysm. Endoleaks are the most common complication after EVAR and require urgent interventions. Usually endoleaks can be treated with endovascular procedures using a variety of techniques. Despite these interventions, if the endoleak still persists, conventional open surgery should be evaluated. A 67-year-old man had been treated with EVAR after a ruptured abdominal aortic aneurysm 7 years ago...
September 2018: Northern Clinics of Istanbul
Ismail Turkmen, Irfan Esenkaya
OBJECTIVE: The early-period results of our technique for performing a medial biplanar retrotubercle open-wedge proximal tibial osteotomy for the surgical treatment of varus gonarthrosis were evaluated and compared with those reported in the literature. METHODS: The clinical and radiological results of a medial biplanar retrotubercle open-wedge proximal tibial osteotomy performed on 23 knees in 22 patients with medial gonarthrosis with varus alignment were analyzed...
September 2018: Northern Clinics of Istanbul
Abdulkadir Uslu, Serdar Demir, Munevver Sari, Cem Dogan, Ozge Akgun, Mehmet Celik, Taylan Akgun
Spontaneous and simultaneous multivessel coronary artery spasm may present with multisite myocardial ischemia, atrioventricular block, acute lung edema, cardiogenic shock, or ventricular fibrillation. In a case of syncope caused by vasospasm, the underlying mechanism may be complex, such as atrioventricular block and/or ventricular arrhythmia. Dual implantable cardioverter defibrillator (ICD) placement should be considered along with optimal medical treatment. This report is a description of a 57-year-old male patient who was admitted to the hospital with chest pain followed by loss of consciousness...
September 2018: Northern Clinics of Istanbul
Ezgi Aslan, Emre Akbas, Sena Yilmaz, Ahmet Salih Karaoglu, Ubeyde Telli, Salih Yildirim, Hilal Gudek, Mahmut Tayyar Kalcioglu, Sarenur Yilmaz, Ibrahim Akalin
OBJECTIVE: The molecular events underlying ear development involve numerous regulatory molecules; however, the role of microRNAs (miRNAs) has not been explored in patients with ear atresia. Here, we aimed to investigate the expressions of 20-22 nucleotide noncoding RNAs. METHODS: We selected 12 miRNAs that function to control post-transcriptional gene expression in different pathways, including apoptosis, angiogenesis, and chondrogenesis. The altered miRNA expressions were analyzed by real-time PCR from serum samples of 7 patients with ear atresia and 8 controls...
September 2018: Northern Clinics of Istanbul
Ulas Aday, Ebubekir Gundes, Durmus Ali Cetin, Huseyin Ciyiltepe, Aziz Serkan Senger, Selcuk Gulmez, Mustafa Akbulut, Erdal Polat
OBJECTIVE: The aim of this study was to investigate the effects of ruptured aneurysm on morbidity and mortality in patients with ischemic colitis (IC) and resection following infrarenal abdominal aortic aneurysms (AAA) surgery. METHODS: Between January 2012 and December 2016, patients who underwent resection for ischemic colitis in our clinic were retrospectively reviewed. Data on the ruptured condition of the aneurysm, the emergency or elective form of aneurysm surgery, treatment method for the aneurysm (EVAR-open) were obtained...
September 2018: Northern Clinics of Istanbul
Bhupinder S Romana, Abdulmajeed A Albarrak, Mohamad H Yousef, Veysel Tahan
Clostridium difficile infection (CDI) is a major cause of morbidity and mortality in patients with inflammatory bowel disease (IBD), especially in ulcerative colitis (UC). The incidence and severity of CDI in IBD has shown an increasing trend in the last two decades. Patients with IBD are predisposed to CDI secondary to the recurrent use of antibiotics, corticosteroids, and immunosuppressants and secondary to dysbiosis. It is clinically challenging to distinguish the symptoms of CDI from an IBD flare. The worsening of IBD symptoms demands escalation of steroids or initiation of biologics...
September 2018: Northern Clinics of Istanbul
Arzu Atici, Ilknur Aktas, Pinar Akpinar, Feyza Unlu Ozkan
OBJECTIVE: Joint hypermobility (JH) is a clinical condition in which the joints move beyond the expected physiological range of motion. JH can be accompanied by many musculoskeletal complaints. One of the common causes of musculoskeletal pain is shoulder pain. The aim of this study was to investigate the relationship between subacromial impingement syndrome (SAIS), shoulder adhesive capsulitis (AC), and JH in patients with shoulder pain. METHODS: Patients aged between 18 and 70 years who presented at the physical medicine and rehabilitation outpatient clinic and who were diagnosed with SAIS or AC in a clinical and physical examination were included in the study...
September 2018: Northern Clinics of Istanbul
Busra Durmaz, Pinar Soysal, Hulya Ellidokuz, Ahmet Turan Isik
OBJECTIVE: The present study aimed to assess the validity and reliability of Geriatric Depression-15 Scale (GDS-15) in Turkish older adults and to compare the results with Diagnostic and Statistical Manual of Mental Disorders-fifth edition (DSM-5) depression criteria. METHODS: A total of 329 outpatients were enrolled. In the first step, the patients underwent the Mini-Mental State Examination. After assessing whether the patients meet the diagnosis of depression based on DSM-5 diagnostic criteria, another researcher applied the long form of GDS...
September 2018: Northern Clinics of Istanbul
Habib Bostan, Murat Cabalar, Serdar Altinay, Yildiray Kalkan, Levent Tumkaya, Ayhan Kanat, Sabri Balik, Adem Erkut, Dudu Altuner, Ziya Salihoglu, Abdulkadir Kocer
OBJECTIVE: Sciatic nerve neuropathy can be observed following intramuscular gluteal injections. The histopathological examination of sciatic nerve damage following intramuscular injection in the gluteal region for acute pain treatment is not feasible in humans due to the inability to dissect and examine the nerve tissue. To overcome this issue, we used a rat model for demonstrating damage to the sciatic nerve tissue after the application of commonly used drug injections. METHODS: We investigated possible damage following the intramuscular injection of diclofenac, lornoxicam, morphine, and pethidine in a rat model based on histopathological characteristics such as myelin degeneration, axon degeneration, epineurium degeneration, fibrosis, epineurium thickening, perineurium thickening, lymphocyte infiltration, vacuolization, and edema...
September 2018: Northern Clinics of Istanbul
Mert Tanal, Mehmet Uludag
No abstract text is available yet for this article.
September 2018: Northern Clinics of Istanbul
Suleyman Demiryas, Turgut Donmez, Erdinc Cekic
No abstract text is available yet for this article.
September 2018: Northern Clinics of Istanbul
Cigdem Pulatoglu, Ozan Dogan, Alper Basbug, Aski Ellibes Kaya, Ahmet Yildiz, Osman Temizkan
OBJECTIVE: It is controversial whether medical or surgical treatment options have more successful results in ectopic pregnancy treatment. Although high pretreatment serum hCG levels have been known to be the most important predictor, the appropriate treatment modality for a specific range of hCG level remains unclear. Furthermore, the variables that make a patient a bad candidate for single-dose methotrexate treatment is unclear. The aim of this study was to identify predictive factors associated with the success of single-dose methotrexate treatment in women with ectopic pregnancy...
September 2018: Northern Clinics of Istanbul
Ahmet Akici, Volkan Aydin, Salih Mollahaliloglu, Senay Ozgulcu, Ali Alkan
OBJECTIVE: Physicians' personal (P) drugs, which were ranked by priority, may show variations even for the same indication. We aimed to evaluate physicians' knowledge and attitudes regarding P-drug list preparation with respect to the rational use of medicine context. METHODS: A total of 1062 family physicians (FPs) and 562 specialist physicians (SPs) were interviewed and questioned about their knowledge and attitude regarding P-drug list preparation. RESULTS: Compared with SPs (64...
September 2018: Northern Clinics of Istanbul
Nizamettin Selcuk Yelgec, Altug Osken, Ceyhan Turkkan, Ahmet Taha Alper
We present a rare and interesting case of subclavian vein puncture-induced focal intraparenchymal lung hemorrhage and massive hemoptysis developed during CRT-D implantation. Clinical picture advanced to pulmonary edema in seconds. A noncontrast multiple-detector computed tomography scan revealed focal alveolar hemorrhage in the lung tissue right under the pacemaker pocket, but remarkably, there was no pneumothorax. This case shows that if cough and hemoptysis suddenly develop during subclavian puncture, injury of the adjoining lung because of parenchymal puncture should be considered as a complication...
September 2018: Northern Clinics of Istanbul
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