Journals International Journal of Retin...

International Journal of Retina and Vitreous
Rodrigo Brant, Luis Filipe Nakayama, Talita Virgínia Fernandes de Oliveira, Juliana Angelica Estevão de Oliveira, Lucas Zago Ribeiro, Gabriela Dalmedico Richter, Rafael Rodacki, Fernando Marcondes Penha
BACKGROUND: Diabetic retinopathy (DR) stands as the foremost cause of preventable blindness in adults. Despite efforts to expand DR screening coverage in the Brazilian public healthcare system, challenges persist due to various factors including social, medical, and financial constraints. Our objective was to evaluate the quality of images obtained with the AirDoc, a novel device, compared to Eyer portable camera which has already been clinically validated. METHODS: Images were captured by two portable retinal devices: AirDoc and Eyer...
June 14, 2024: International Journal of Retina and Vitreous
Lorenzo Ferro Desideri, Rodrigo Anguita, Lieselotte E Berger, Helena M A Feenstra, Davide Scandella, Raphael Sznitman, Camiel J F Boon, Elon H C van Dijk, Martin S Zinkernagel
AIM: To adopt a novel artificial intelligence (AI) optical coherence tomography (OCT)-based program to identify the presence of biomarkers associated with central serous chorioretinopathy (CSC) and whether these can differentiate between acute and chronic central serous chorioretinopathy (aCSC and cCSC). METHODS: Multicenter, observational study with a retrospective design enrolling treatment-naïve patients with aCSC and cCSC. The diagnosis of aCSC and cCSC was established with multimodal imaging and for the current study subsequent follow-up visits were also considered...
May 31, 2024: International Journal of Retina and Vitreous
José Henrique Casemiro, Ana Paula Miyagusko Taba Oguido, Antonio Marcelo Barbante Casella
BACKGROUND: The use of povidone-iodine for ocular surface asepsis is widespread for intravitreal injections. They became frequent procedures, leading to serial exposure of patients' eyes to iodinated solutions. In this study, we investigate the changes in the ocular surface in patients submitted to repeated use of povidine for intravitreal injection of anti-VEGF asepsis, analyzing Ocular Surface Disease Index, non-invasive break up time, blinking quality, lipid layer, meniscus height and osmolarity...
May 29, 2024: International Journal of Retina and Vitreous
Mia Karabeg, Goran Petrovski, Silvia Nw Hertzberg, Maja Gran Erke, Dag Sigurd Fosmark, Greg Russell, Morten C Moe, Vallo Volke, Vidas Raudonis, Rasa Verkauskiene, Jelizaveta Sokolovska, Inga-Britt Kjellevold Haugen, Beata Eva Petrovski
BACKGROUND: Diabetic retinopathy (DR) is the leading cause of adult blindness in the working age population worldwide, which can be prevented by early detection. Regular eye examinations are recommended and crucial for detecting sight-threatening DR. Use of artificial intelligence (AI) to lessen the burden on the healthcare system is needed. PURPOSE: To perform a pilot cost-analysis study for detecting DR in a cohort of minority women with DM in Oslo, Norway, that have the highest prevalence of diabetes mellitus (DM) in the country, using both manual (ophthalmologist) and autonomous (AI) grading...
May 23, 2024: International Journal of Retina and Vitreous
Zuzana Anwarzai Sulavikova, Zuzana Sustykevicova, Marek Kacerik, Vladimir Krasnik
BACKGROUND: The aim of this study is to evaluate near and distance visual acuity (VA) and their correlation with the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) outcomes in patients with diabetic macular edema (DME) and macular edema due to retinal vein occlusion (RVO) treated with aflibercept. METHODS: In this prospective study, we included 87 eyes of patients diagnosed with DME (n = 61) and RVO (n = 26), who received aflibercept treatment and were followed until the 8th injection...
May 23, 2024: International Journal of Retina and Vitreous
Rami Al-Dwairi, Tamam El-Elimat, Abdelwahab Aleshawi, Ahmed Al Sharie, Seren Al Beiruti, Abdallah K Sharayah, Mohammed Allouh
BACKGROUND: This study aims to investigate the factors affecting the vitreous levels of pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VGEF) among patients with pars plana vitrectomy (PPV). Also, this study correlates the levels of PEDF with RRD characteristics. METHODS: All patients who were scheduled for PPV for any indication were included in the study. They were divided into a case group which included patients with advanced PDR and a control group which included the remaining diagnoses...
May 21, 2024: International Journal of Retina and Vitreous
Samir Touma, Badr Ait Hammou, Fares Antaki, Marie Carole Boucher, Renaud Duval
BACKGROUND: Code-free deep learning (CFDL) is a novel tool in artificial intelligence (AI). This study directly compared the discriminative performance of CFDL models designed by ophthalmologists without coding experience against bespoke models designed by AI experts in detecting retinal pathologies from optical coherence tomography (OCT) videos and fovea-centered images. METHODS: Using the same internal dataset of 1,173 OCT macular videos and fovea-centered images, model development was performed simultaneously but independently by an ophthalmology resident (CFDL models) and a postdoctoral researcher with expertise in AI (bespoke models)...
April 26, 2024: International Journal of Retina and Vitreous
Miguel A Quiroz-Reyes, Zaheer-Ud-Din Babar, Rabia Hussain, Zhe Chi Loh, Erick A Quiroz-Gonzalez, Miguel A Quiroz-Gonzalez, Virgilio Lima-Gomez
BACKGROUND: Rhegmatogenous retinal detachment (RRD) is a serious condition that occurs when the retina detaches from its underlying retinal pigment epithelium. RRDs associated with giant retinal tears (GRTs) are caused by retinal tears at least 90° or one-quarter of the circumferential extent. This scoping review systematically identifies and summarizes clinical studies evaluating surgical techniques for the management of GRT-related RRDs, discusses functional and visual outcomes and the risk factors affecting treatment outcomes...
April 23, 2024: International Journal of Retina and Vitreous
Matthew Driban, Audrey Yan, Amrish Selvam, Joshua Ong, Kiran Kumar Vupparaboina, Jay Chhablani
BACKGROUND: Applications for artificial intelligence (AI) in ophthalmology are continually evolving. Fundoscopy is one of the oldest ocular imaging techniques but remains a mainstay in posterior segment imaging due to its prevalence, ease of use, and ongoing technological advancement. AI has been leveraged for fundoscopy to accomplish core tasks including segmentation, classification, and prediction. MAIN BODY: In this article we provide a review of AI in fundoscopy applied to representative chorioretinal pathologies, including diabetic retinopathy and age-related macular degeneration, among others...
April 23, 2024: International Journal of Retina and Vitreous
Matheus Senna Pereira Ogata, Guilherme Rodrigues Ferreira, Melina Correia Morales, Arthur Gustavo Fernandes
OBJECTIVE: Ocular metastases are the most common intraocular tumours in adults. Data regarding the occurrence of these tumours in the Brazilian population is scarce. We aimed to investigate the profile of ocular metastases of patients referred to tertiary hospital service in São Paulo, Brazil. DESIGN: Retrospective study. PARTICIPANTS: Patients referred to the Ocular Oncology service of the Federal University of São Paulo with initial diagnostic hypothesis of ocular metastasis...
April 16, 2024: International Journal of Retina and Vitreous
Ramon Antunes De Oliveira, Vinicius Oliveira Pesquero, Lucas Zago Ribeiro, Murilo Ubukata Polizelli, Aalec Rinhel Souza Ferreira Da Silva, Nilva Simeren Bueno De Moraes, Rodrigo Antonio Brant Fernandes, Octaviano Magalhaes Junior, Mauricio Maia
BACKGROUND: Describe complications and clinical outcomes of heavy silicone oil (HSO) Oxane HD® use as an alternative to overcome the challenges of performing vitrectomy to treat tractional and rhegmatogenous retinal detachments with proliferative vitreoretinopathy (PVR). METHODS: A retrospective, observational study was performed on patients from one center from August 2014 to Aug 2023. It was included patients who underwent surgery using HSO Oxane HD® to treat rhegmatogenous retinal detachment with PVR or mixed tractional and rhegmatogenous diabetic retinal detachment...
April 11, 2024: International Journal of Retina and Vitreous
Ryoh Funatsu, Hiroto Terasaki, Naohisa Mihara, Shozo Sonoda, Hideki Shiihara, Taiji Sakamoto
BACKGROUND: To compare the one-year outcomes between intravitreal brolucizumab (IVBr) monotherapy and photodynamic therapy (PDT) as a second-line treatment in patients with polypoidal choroidal vasculopathy (PCV) who did not respond to first-line therapy. METHODS: This case-control study included eyes with PCV that do not respond to aflibercept or ranibizumab. The patients were retrospectively registered. We compared outcomes, including best-corrected visual acuity (BCVA), anatomical results, and the need for additional treatments, between IVBr and a combination therapy using PDT as second-line treatments for refractory PCV, after adjusting for potential confounders...
April 8, 2024: International Journal of Retina and Vitreous
Virginia Mares, Marcio B Nehemy, Hrvoje Bogunovic, Sophie Frank, Gregor S Reiter, Ursula Schmidt-Erfurth
Artificial intelligence (AI) has emerged as a transformative technology across various fields, and its applications in the medical domain, particularly in ophthalmology, has gained significant attention. The vast amount of high-resolution image data, such as optical coherence tomography (OCT) images, has been a driving force behind AI growth in this field. Age-related macular degeneration (AMD) is one of the leading causes for blindness in the world, affecting approximately 196 million people worldwide in 2020...
April 8, 2024: International Journal of Retina and Vitreous
Ameen Marashi, Marwa Baba, Sedra Abu Ghedda, Mohammad Nour Kitaz, Aya Zazo
BACKGROUND: Previous studies have shown promising effects of combining intravitreal bevacizumab and suprachoroidal injection of triamcinolone acetonide in treating DME. However, further research is needed. OBJECTIVE: To assess the efficacy and safety of combining both intravitreal Ziv-aflibercept and suprachoroidal injection of triamcinolone acetonide using a custom-made needle in naïve and de novo central diabetic macular edema (DME) patients every eight weeks for 24 weeks...
April 2, 2024: International Journal of Retina and Vitreous
Josef Huemer, Tjebo Fc Heeren, Abraham Olvera-Barrios, Livia Faes, Antonio M B Casella, Edward Hughes, Adnan Tufail, Catherine Egan
No abstract text is available yet for this article.
March 25, 2024: International Journal of Retina and Vitreous
Josef Huemer, Tjebo Fc Heeren, Abraham Olvera-Barrios, Livia Faes, Antonio M B Casella, Edward Hughes, Adnan Tufail, Catherine Egan
PURPOSE: Although diabetes is highly prevalent in patients with MacTel, progression to severe non-proliferative (NPDR) and proliferative diabetic retinopathy (PDR) is rarely reported. We report multimodal imaging features of sight-threatening diabetic retinopathy (STDR) in eyes with macular telangiectasia type 2 (MacTel). METHODS: Retrospective case series of seven participants of the MacTel Study at the Moorfields Eye Hospital NHS Foundation Trust study site and one patient from the Institute of Retina and Vitreous of Londrina, Brazil...
March 12, 2024: International Journal of Retina and Vitreous
Zahra Saeedi-Maleki, Alireza Javadzadeh, Fariborz Brumandpur, Amir Ghorbanihaghjo, Shokoufeh Khanzadeh, Farideh Mousavi
PURPOSE: Our objective was to compare the serum Adropin levels between patients with wet-type Age-Related Macular Degeneration (AMD) and otherwise healthy individuals. METHOD: The study included 45 patients with wet-type AMD and 45 individuals without age-related macular degeneration. Patients with co-morbidities such as diabetes, hypertension, autoimmune diseases, and a previous history of visual impairment; were excluded. FBS, Hemoglobin A1C (HbA1C), lipid profile, and serum Adropin level were checked...
March 12, 2024: International Journal of Retina and Vitreous
Fillipe de Biaggi Borges da Silva, Luis Claudio Pimentel Silva, Leonardo Provetti Cunha, Leandro Cabral Zacharias, Eduardo V Navajas, Mario L R Monteiro, Rony C Preti
PURPOSE: To assess the relationship between macular choroidal thickness (CT) measurements and retinal sensitivity (RS) in eyes with myopia and different stages of myopic maculopathy. METHODS: A masked, cross-sectional, and consecutive study involving patients with emmetropia/myopia (control group) and high myopia (HM) eyes. Automated choroidal thickness (CT) and manual outer retinal layer (ORL) thickness were acquired using swept-source optical coherence tomography, while retinal sensitivity (RS) assessed by microperimetry (MP3) in all regions of the macular Early Treatment Diabetic Retinopathy Study (ETDRS) grid...
March 8, 2024: International Journal of Retina and Vitreous
Hamid Riazi-Esfahani, Abdulrahim Amini, Babak Masoomian, Mehdi Yaseri, Siamak Sabour, Ali Rashidinia, Mojtaba Arjmand, Seyed Mohsen Rafizadeh, Mohammadkarim Johari, Elias Khalili Pour, Fariba Ghassemi
BACKGROUND: To assess the characteristics and outcomes of uveal melanoma management at a tertiary center in the Middle East. METHODS: A study on 164 patients with uveal melanoma was conducted by reviewing the available medical records, ultrasound, and pathology report results. Age at diagnosis, tumor location and size, treatment mode, visual outcome, metastasis, mortality, and survival were studied. RESULTS: The mean age of patients was 52...
March 1, 2024: International Journal of Retina and Vitreous
Dillan Cunha Amaral, Mark Lane, Eduardo Henrique Cassins Aguiar, Guilherme Nunes Marques, Luiza Visentin Cavassani, Márcio Penha Morterá Rodrigues, Milton Ruiz Alves, José Eduardo Ferreira Manso, Mário Luiz Ribeiro Monteiro, Ricardo Noguera Louzada
BACKGROUND: Toxoplasma gondii causes ocular toxoplasmosis (OT), involving inflammation, scarring, and retinal complications. The OT complications were retinal detachment (RD), and retinal breakage (RB). Surgical interventions like scleral buckling (SB) and vitrectomy are common. Limited understanding exists of the safety and efficacy of surgical management of RD/RB secondary to OT. Another complication is toxoplasmosis-related macular holes (tMH), with sparse evidence on surgical outcomes...
February 29, 2024: International Journal of Retina and Vitreous
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