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Journals Laryngoscope Investigative Oto...

Laryngoscope Investigative Otolaryngology

https://read.qxmd.com/read/37731860/anticancer-effects-of-thymoquinone-in-head-and-neck-squamous-cell-carcinoma-a-scoping-review
#1
REVIEW
Kera Kwan, Albert Y Han, Laith Mukdad, Frida Barragan, Omar Selim, Yazeed Alhiyari, Maie St John
OBJECTIVE: Thymoquinone (TQ), the active constituent of Nigella sativa , has been shown to have anticancer effects in head and neck squamous cell carcinoma (HNSCC). This review aims to outline the properties of TQ, the known drivers in HNSCC formation, and summarize the anticancer effects of TQ in SCC. DATA SOURCES: Three databases (PubMed, Embase, and Google Scholar) were queried for the key words "thymoquinone squamous cell carcinoma." REVIEW METHODS: Publications that were not original research and publications that did not have full-text available for review were excluded...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621300/treatment-of-sinus-headache-using-a-device-that-combines-acoustic-vibration-with-oscillating-expiratory-pressure
#2
JOURNAL ARTICLE
Amar Miglani, Matthew Germroth, Kristina A LaPointe, Shaun A Nguyen, Ted A Meyer
OBJECTIVE: To determine if simultaneous administration of acoustic vibration and oscillating expiratory pressure affects the severity of facial pain among patients with complaint of "sinus headache". METHODS: This is a prospective single-arm observational study performed at a tertiary care medical center. Subjects with complaint of sinus headache without evidence of chronic rhinosinusitis on exam or computed tomography participated in a clinical study applying simultaneous acoustic vibrations and positive expiratory pressure to the nasal cavity twice daily over 4 weeks...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621299/effectiveness-of-vocal-fold-medialization-surgery-on-the-swallowing-function-of-patients-with-unilateral-vocal-fold-paralysis
#3
JOURNAL ARTICLE
Takeyuki Kono, Shuta Tomisato, Hiroyuki Ozawa
OBJECTIVES: Vocal fold medialization surgery is generally considered a phonosurgical procedure for improvement of vocal function in patients with glottic insufficiency. However, the literature describing this procedure for the management of dysphagia is limited. This study aims to assess the effects of medialization surgery on swallowing function in patients with unilateral vocal fold paralysis (UVFP). METHODS: We enrolled 32 patients with UVFP undergoing vocal fold medialization surgery (medialization laryngoplasty combined with arytenoid adduction [ML + AA], 12 cases; injection laryngoplasty [IL], 20 cases)...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621298/facial-plating-industry-payments-an-analysis-of-the-open-payments-database
#4
JOURNAL ARTICLE
F Jeffrey Lorenz, Brandon LaBarge, Jessyka G Lighthall, Scott G Walen
OBJECTIVE: To compare industry payments from facial plating companies to plastic surgery, oral and maxillofacial surgery (OMFS), and otolaryngology (OHNS). METHODS: The Open Payments Database was queried from 2016 to 2021 to identify all industry disbursements related to facial plating products from Stryker, Zimmer Biomet, Depuy Synthes Products, Acumed, and KLS Martin. Total dollars, number of payments, and specialists paid were compared between plastic surgery, OMFS, and OHNS...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621297/systematic-review-validity-reliability-and-diagnostic-accuracy-of-the-electrogustometer
#5
REVIEW
Esther E Blijleven, Denise Fuchten, Max J Dullaart, Robert J Stokroos, Henricus G X M Thomeer, Inge Wegner
OBJECTIVE: What are the electrogustometer's (EGM) validity, reliability, and diagnostic accuracy in assessing taste sensation in adults compared to other taste tests? DATA SOURCES: PubMed Medline, Elseviers's Embase, and the six databases of Cochrane Library. METHODS: We conducted a systematic search on December 20, 2022, consisting of synonyms for EGM. We considered randomized controlled trials and observational studies with original data for inclusion if they included adults who underwent electrogustometry...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621296/three-dimensionally-visualized-ossification-and-mineralization-process-of-the-otic-capsule-in-a-postnatal-developmental-mouse
#6
JOURNAL ARTICLE
Jing Bai, Taku Ito, Taro Fujikawa, Keiji Honda, Yoshiyuki Kawashima, Hiroki Watanabe, Natsuko Kurata, Takeshi Tsutsumi
OBJECTIVE: We aimed to elucidate the ossification process of the otic capsule in postnatal C57BL/6 mice and depict the three-dimensional (3D) process of otoconial mineralization in vivo. METHODS: The otic capsules of C57BL/6 mice were stained with alizarin red and imaged/compared using micro-computed tomography on postnatal day (P) between P0 and P8, P10, P15, and P30 and 3-4 months old (P3-4Mo). We reconstructed 3D images of the otic capsule and otoconia and measured the bone mineral density using x-ray absorptiometry on each age...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621295/outcomes-of-cochlear-implantation-in-early-deafened-patients-with-waardenburg-syndrome-a-systematic-review-and-narrative-synthesis
#7
REVIEW
Amy Lovett, Michael Eastwood, Chris Metcalfe, Jameel Muzaffar, Peter Monksfield, Manohar Bance
OBJECTIVE: This systematic review aims to establish the expected hearing and speech outcomes following cochlear implantation (CI) in patients with profound congenital deafness secondary to Waardenburg syndrome (WS). METHODS: A systematic review of the literature and narrative synthesis was performed in accordance with the PRISMA statement. Databases searched: Medline, Pubmed, Embase, Web of Science, Cochrane Collection, and ClinicalTrials.gov. No limits were placed on language or year of publication...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621294/competency-based-medical-education-in-the-united-states-what-the-otolaryngologist-needs-to-know
#8
REVIEW
Jenny X Chen, Marc C Thorne, Deepa Galaiya, Paolo Campisi, Stacey T Gray
Competency-based medical education (CBME) is an outcomes-focused approach to educating medical professionals that will be central to future efforts to improve resident training in otolaryngology. The transition to CBME for otolaryngology in the United States will require the development of specialty-specific assessments and benchmarks, the financial and administrative support for implementation, the professional development of faculty and learners, and the cooperation of all major stakeholders in graduate medical education...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621293/usefulness-of-a-newly-developed-endoscope-for-the-observation-of-the-posterior-tracheal-wall
#9
JOURNAL ARTICLE
Tomoe Tamai, Kanako Yoshimi, Kazuharu Nakagawa, Ryosuke Yanagida, Takuma Okumura, Kohei Yamaguchi, Miki Ishii, Yuki Nagasawa, Haruka Tohara
OBJECTIVE: Videoendoscopic evaluation of swallowing is an objective swallowing function evaluation method used in dysphagia rehabilitation. However, it is anatomically difficult to detect the entry of foreign substances through the posterior tracheal wall using a conventional endoscope (CE). In this study, we developed an endoscope that can observe the posterior tracheal wall and investigated its reliability and validity in healthy adults. METHODS: Twenty healthy adults were included...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621292/the-effect-of-self-management-vestibular-rehabilitation-on-persistent-postural-perceptual-dizziness
#10
JOURNAL ARTICLE
Chisato Fujimoto, Mineko Oka, Kentaro Ichijo, Makoto Kinoshita, Teru Kamogashira, Keiko Sugasawa, Takuya Kawahara, Tatsuya Yamasoba
OBJECTIVE: To investigate the effects of self-management vestibular rehabilitation (VR) on the subjective symptoms of dizziness and postural stability in persistent postural-perceptual dizziness (PPPD). STUDY DESIGN: Retrospective case review. METHODS: The medical records of 30 patients newly diagnosed with PPPD based on the Bárány Society's diagnostic criteria were reviewed. Nineteen patients (4 males and 15 females; age range 27-84 years, mean age ± standard deviation 57...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621291/treatment-of-buccal-mucosal-carcinomas-a-survey-amongst-head-and-neck-surgeons-in-the-netherlands
#11
JOURNAL ARTICLE
Carleen M E M Adriaansens, Rob Noorlag, Remco de Bree, Robert J J van Es
OBJECTIVE: Currently, there is no up-to-date guideline for the treatment of buccal mucosal squamous cell carcinoma (BMSCC) in the Netherlands. A questionnaire was used to investigate the opinions of Dutch head and neck surgeons on BMSCC of the cheek treatment. METHODS: A questionnaire was sent to all 91 head and neck surgeons in the Netherlands. Their opinions on surgical tumor-free margins, through-and-through defects, and indications for local adjuvant therapy were questioned...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621290/relationship-among-five-factor-personality-traits-and-psychological-distress-with-acoustic-analysis
#12
JOURNAL ARTICLE
Saeed Saeedi, Payman Dabirmoghaddam, Mehdi Soleimani, Mahshid Aghajanzadeh
OBJECTIVES: The relationship between personality traits and psychological distress with acoustic characteristics was investigated in the present study, regarding the existence of dysphonia, abnormal overall voice quality (AOVQ), and dysphonia type. METHODS: Fifty-five participants with dysphonia and 64 participants without dysphonia completed NEO Five-Factor Inventory and Depression, Anxiety, and Stress Scale-21. Jitter, shimmer, noise-to-harmonic ratio (NHR), cepstral peak prominence (CPP), and cepstral peak prominence-smoothed (CPPS) were calculated in sustained vowel /a/ by Praat ...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621289/deployment-of-cisplatin-in-veterans-with-oropharyngeal-cancer-toxicity-and-impact-on-oncologic-outcomes
#13
JOURNAL ARTICLE
Ola Soliman, David C Wilde, Jan O Kemnade, Anita L Sabichi, George Chen, Albert Chen, Samantha N Little, Andrew T Huang, David J Hernandez, Vlad C Sandulache
OBJECTIVE: Cisplatin forms the backbone of systemic chemotherapy treatment for oropharyngeal squamous cell carcinoma (OPSCC). The ideal cisplatin dosing regimen remains yet to be fully defined for achieving optimal efficacy and toxicity profiles in patients with comorbidity. METHODS: We retrospectively reviewed oncologic and toxicity data for patients with OPSCC treated at the Michael E. DeBakey Veterans Affairs Medical Center between 2000 and 2020 who initiated curative intent, definitive chemo-radiation with one of three single agent regimens: high dose (HD) cisplatin, low dose (LD) cisplatin or cetuximab...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621288/reliability-and-validity-of-the-polish-version-of-the-questionnaire-of-olfactory-disorders
#14
JOURNAL ARTICLE
Natalia Tuz-Hrycyna, Anna Rzepakowska, Kazimierz Niemczyk
BACKGROUND: The comprehensive counseling of patients with olfactory dysfunctions requires accurate diagnosis. The recommendations include subjective assessment. The Questionnaire of Olfactory Disorders (QOD) is a disease-specific questionnaire for the subjective evaluation of olfactory dysfunctions. MATERIAL: The study included 54 patients with olfactory dysfunctions, who were recruited to the study group (SG). The other 47 patients without the history of olfactory dysfunction and nasal cavity pathology were voluntarily allocated to the control group (CG)...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621287/primary-versus-salvage-intratympanic-steroid-treatment-for-idiopathic-sudden-sensorineural-hearing-loss
#15
JOURNAL ARTICLE
Wei-Che Lan, Chia-Der Lin, Yung-An Tsou, Liang-Chun Shih, Yu Aoh, Chien-Chi Lu, Hsiu-San Hsu, Chun-Yu Lai, Ching-Yuan Wang
OBJECTIVE: The objective of this research is to compare primary and salvage intratympanic (IT) steroid treatments in terms of hearing outcomes in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). METHODS: The patients were randomized into two (primary and salvage) groups. Both groups received systemic steroid treatment for 2 weeks. The primary group also received IT dexamethasone injection three times during the treatment period, whereas the salvage group received IT dexamethasone injection only if no or slight recovery was noted at the 2-week follow-up...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621286/laryngeal-cancer-treatment-decision-making-a-conjoint-analysis-of-general-public-attitudes-and-priorities
#16
JOURNAL ARTICLE
Montana Upton, Neha Reddy, Mamdouh Aker, Kevin James, Marilene Wang, Abie H Mendelsohn
OBJECTIVE: Patients with advanced laryngeal cancer are typically presented with divergent treatment options, namely chemoradiation versus total laryngectomy. This study aims to understand general perspectives of the factors involved in this decision-making process. METHODS: Surveys were constructed using specialized conjoint analysis software. Seven attributes integral to the decision-making process for advanced laryngeal cancer treatment were included. RESULTS: Three hundred one healthy adult volunteers completed the decision-making program...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621285/a-retrospective-study-of-134-patients-with-cervical-region-kikuchi-fujimoto-disease
#17
JOURNAL ARTICLE
Jianzhi Liu, Qiaoling Zheng, Liangwen Shi, Zhiwei Zhao, Xuxiang Chen, Taiqin Wang, Xiaoqiang Chen
BACKGROUND: To explore the clinical and laboratory features, therapy and prognosis of Kikuchi-Fujimoto disease (KFD) in the cervical region. METHODS: We retrospectively reviewed the medical records of 134 patients who were diagnosed and treated with KFD from January 2000 to May 2022 in Fujian Medical University Union Hospital (Fujian, China). Their clinical characteristics, affected lymph node size, imaging examinations, and laboratory study results were analyzed...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621284/-nigella-sativa-oil-mitigates-xerostomia-and-preserves-salivary-function-in-radiotherapy-treated-mice
#18
JOURNAL ARTICLE
Marie Luff, Lauran Evans, Sarah Hiyari, Kera Kwan, Brian Cameron, Amanda Miller, Maie St John, Yazeed Alhiyari
OBJECTIVE: This study aimed to assess if Nigella sativa oil (NSO), a health supplement containing thymoquinone as a major component, can act as a protective agent in salivary gland stem cells following radiotherapy (RT) damage. METHODS: Forty, 10-week-old, male C3H/HeJ mice were randomized to four experimental groups: sham RT + H2 O gavage (control) ( N  = 4); 15 Gy RT + H2 O gavage ( N  = 12); sham RT + NSO gavage ( N  = 12); and 15 Gy RT + NSO gavage ( N  = 12)...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621283/regional-distribution-in-female-representation-in-us-otolaryngology-faculty
#19
JOURNAL ARTICLE
Esther Wang, Ashley Diaz, Maha L Khan, Elizabeth A Blair, Andrea N Shogan
OBJECTIVES: To quantify the current proportion of women in otolaryngology at different levels of professorship and determine whether these proportions differ by US region. METHODS: Academic rank and gender at all ACGME-accredited otolaryngology programs in the United States were determined from departmental websites, Doximity, and LinkedIn from November 2021 to March 2022. Individuals were then further organized using US Census Bureau-designated regions. RESULTS: Among the 2682 faculty positions at 124 ACGME-accredited programs, women held 706 (26...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37621282/differences-in-vestibulo-ocular-reflexes-between-vestibular-neuritis-and-labyrinthitis
#20
JOURNAL ARTICLE
Gi-Sung Nam, Wonyong Baek, Min Seok Kim, Sung Il Cho
OBJECTIVE: To expand our understanding of the pathophysiological mechanisms underlying vestibular neuritis and labyrinthitis by identifying any difference in the vestibulo-ocular reflex for each semicircular canal. STUDY DESIGN: Retrospective analysis. SETTING: The Department of Otorhinolaryngology - Head and Neck Surgery, Chosun University Hospital, from January 2015 to December 2021. METHODS: We included 23 vestibular neuritis and 27 labyrinthitis patients who had been hospitalized...
August 2023: Laryngoscope Investigative Otolaryngology
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