Yuta Mizunuma, Tsuneari Takahashi, Masaki Iguchi, Hideyuki Sasanuma, Akihiro Saitsu, Mikiko Handa, Tomohiro Matsumura, Katsushi Takeshita
A 72-year-old female patient with a fixed valgus knee deformity due to a Schatzker type V tibial plateau fracture treated with bilateral locking plates 8 years ago was admitted to our clinic with complaints of chronic pain and knee instability when walking. Radiographs revealed Kellgren-Lawrence Classification grade 4 knee osteoarthritis and 20.5° of valgus knee deformity. She was treated with three-dimensional templating and proximal lateral tibial fitting patient-specific instrumentation-assisted mechanically aligned posterior sacrificing total knee arthroplasty with minimal removal of the retained hardware for the internal fixation of the tibial plateau fracture via a lateral approach, resulting in a favorable clinical outcome...
2023: SAGE Open Medical Case Reports
Jade Conway, Shari R Lipner
Overall, 80%-90% of patients with psoriasis will have nail involvement at some point during their lifetime, and nail changes, on average, are more common in patients with longer disease duration. Since there is accelerated keratinocyte proliferation and cell turnover in cutaneous psoriasis plaques compared to normal skin, it has been hypothesized that psoriasis increases nail growth rate. We describe a case of a 44-year-old male with a 10-year history of cutaneous and nail psoriasis, with acceleration in nail growth rate for 2 years prior to presentation...
2023: SAGE Open Medical Case Reports
Guadalupe Sauchelli-Faas, Antonio Barragán-Acea, Hugo Álvarez-Argüelles, Javier Montoto-López, Juan José Jiménez-Rivera, Rafael Martínez-Sanz
Primary cardiac tumours are rare and most of them are benign. Myxomas, fibroelastomas and lipomas are common in adults. Primary valvular cardiac tumours are even more rare and affect all four valves in a similar proportion. Valvular lipomas are very rare. In the pulmonary valve there is only one described. Lipomas can be spindle-cell varieties. But of these, there is only one described in a valve, and it is placed in the aortic valve. Pulmonary valve lipomas can produce obstruction to the right ventricular outflow tract as well as pulmonary valve regurgitation, or pulmonary embolism...
2023: SAGE Open Medical Case Reports
Sarah Oliel, Sarah Moussa, Monica Stanciu, Elena Netchiporouk
Alopecia universalis is a severe, difficult to treat variant of alopecia areata that results in loss of hair on the scalp, eyebrows, eyelashes, and extremities. Deucravacitinib, a selective TYK2 inhibitor, has been recently approved in Canada, opening the door to novel uses of the drug. We present the case of a patient known for psoriasis who developed alopecia universalis resistant to many interventions (topical minoxidil and topical, intralesional, and systemic corticosteroids). We report the first case of successful rapid hair regrowth after starting deucravacitinib, which should prompt further inquiry into the use of TYK2 inhibitors in the management of alopecia areata...
2023: SAGE Open Medical Case Reports
Mohammed Alyousef, Saud Alromaih, Bayan Aldokheel, Ahmad Alroqi
Silent sinus syndrome refers to a spontaneous enophthalmos caused by maxillary sinus collapse without any symptomatic sinonasal illnesses. Its prevalence is almost entirely unilateral. The authors report a patient with a bilateral silent sinus syndrome managed successfully by middle meatal antrostomies. This case brings attention to recognizing bilateral silent sinus syndrome. Because of its bilateral involvement, the facial disfigurement might be recognized late due to the symmetrical presentation. This article highlights the pathophysiology and reports the detailed course of such a rare disease...
2023: SAGE Open Medical Case Reports
Yassine Saadi, Alae Neqrachi, Mohamed Saleh Berrada
Congenital proximal radioulnar synostosis limits prono-supination and is often well tolerated. Only one publication in the literature describes a fracture associated with this malformation. We report a case of radius and ulna shaft fractures in a 35-year-old patient with well-tolerated bilateral proximal congenital proximal radioulnar synostosis.
2023: SAGE Open Medical Case Reports
Mohamed Jlidi, Walid Bouaicha, Saffet Nouicer, Karim Mallek, Imene Chaabane, Sabrine Bachrouch, Selim Daas
Sternoclavicular joint septic arthritis is rare and commonly associated with specific risk factors. We report the case of a 58-year-old female with no previous medical or surgical history who presented complaining of a warm, indurated mass overlying the right sternoclavicular joint. Computed tomography of the chest showed erosion of the sternal end of the clavicle and the manubrium sternum associated with thickening of the synovium and a sternoclavicular joint space narrowing, suggestive of an infective process...
2023: SAGE Open Medical Case Reports
François Charron-Ligez, Delphine Désy, Marie-Hélène Auclair
Paclitaxel is a drug frequently used in the treatment of gynecological cancers. Its cutaneous side effects are fairly well documented. A subtype of hand-foot syndrome, periarticular erythema of the thenar eminences with onycholysis, is rarer. Here, we present a case of a woman treated with paclitaxel for recurrent ovarian cancer who developed periarticular thenar eminence erythema with onycholysis syndrome. Involvement presented as an erythematous rash on the top of the left hand progressing up the arm. A lesion was also present on the right lower limb and on the dorsal surface of the right foot with onycholysis...
2023: SAGE Open Medical Case Reports
Can C Süsal, Leonie Kraft, Andrea Ender, Caner Süsal, Amelie Schwenger, Kerstin Amann, Georg A Böhmig, Vedat Schwenger
We report a case of antibody-mediated rejection treated with the human CD38 monoclonal antibody daratumumab in a 58-year-old female patient with end-stage kidney disease due to autosomal dominant polycystic kidney disease who received an ABO- and human leukocyte antigen antibody-incompatible living donor kidney transplant. The patient experienced an episode of severe antibody-mediated rejection within the first week of transplantation. Blood-group-antibody selective immunoadsorption in combination with administration of four doses of daratumumab (each 1800 mg s...
2023: SAGE Open Medical Case Reports
Krystal Stewart, Doha Itani, Andrew Mulherin, Robert Hayes
Proliferating pilar tumors are rare, benign, exophytic neoplasms, which can closely resemble a squamous cell carcinoma. We describe a patient with a large benign exophytic tumor on the scalp that had been slowly growing over 10 years. While this class of benign follicular tumors is rare, the standard of care is typically excision with clear histologic margins. In this case, this large scalp tumor was surgically excised with clear margins/permanent section margin control using "Slow Mohs" technique, with subsequent repair using a skin substitute dressing, followed by a delayed skin graft...
2023: SAGE Open Medical Case Reports
Hunza Chaudhry, Aalam Sohal, Humzah Iqbal, Uzair Chaudhary, Marina Roytman
Hepatocellular carcinoma is an increasingly frequent cause of cancer-related death. The majority of patients with hepatocellular carcinoma are asymptomatic. In rare cases, patients may present with symptoms of extrahepatic metastases. Early identification can lead to timely treatment and prevent poor outcomes. We report three cases of patients with hepatocellular carcinoma with unusual sites of metastasis, including clival, mandible, and cardiac involvement.
2023: SAGE Open Medical Case Reports
Spencer Tuohy, Christopher Wachuku, Yixin A Wang, Aman Prasad, Sara S Samimi, Lisa K Pappas-Taffer, Paul L Haun, Leo L Wang
This case describes a patient with known mantle cell lymphoma without cutaneous involvement presenting with a diffuse morbilliform rash during an inpatient admission for bacterial pneumonia. The patient was thought to have a hypersensitivity to antibiotics but failed to improve after the offending agents were stopped. A skin biopsy revealed metastatic cutaneous mantle cell lymphoma. Treatment with high-dose corticosteroids and chemotherapy was initiated resulting in the resolution of the rash.
2023: SAGE Open Medical Case Reports
Talia Unice, Poobalan Naidoo, Pranav Hiralal, Yeshkir Naidoo, Somasundram Pillay
Cerebral aneurysms secondary to human immunodeficiency virus vasculopathy are a diagnosis by exclusion and its mechanism is unknown. We report on a 21-year-old male with human immunodeficiency virus infection and suboptimal virological control, despite highly active antiretroviral therapy. An incidental discovery of multiple cerebral aneurysms occurred in this patient, who initially presented with signs of disorientation, acute psychosis, and a history of blunt cranial trauma. A non-contrasted computerized tomography scan of the encephalon showed no intracranial hemorrhage but multiple cerebral (saccular and fusiform) aneurysms...
2023: SAGE Open Medical Case Reports
Chiraz Regaieg, Anouar Jarraya, Saloua Ammar, Souha Kallel, Imen Maaloul, Fathi Karray, Riadh Mhiri, Kamel Kolsi, Afef Ben Thabet, Nedia Hmida
Airway management in neonates is difficult because of the risk of rapid hypoxia. It presents a challenge even for an experienced anesthesiologist. Oral tumors in neonates can obstruct the airway or feeding problems in the newborn. Surgical excision is the treatment of choice but these tumors can seriously worsen the conditions of intubation. To surmount these difficulties, a particular multidisciplinary approach and special precautions are needed. We describe the airway management and precautions taken in the anesthesia for surgical removal of a case of large congenital palate teratoma associated with a wide cleft palate in a 25-day-old girl...
2023: SAGE Open Medical Case Reports
Fiona M Landells, Shaina Goudie, Jerry McGrath, Jamie Tibbo, Ian Dr Landells
Erosive lichen planus is a chronic auto-inflammatory disease which affects the stratified squamous epithelia resulting in painful ulcerations of both the skin and mucosal surfaces, and has a known malignant potential. Management of erosive lichen planus has proven to be difficult; however, recent reports of treatment with Janus kinase inhibitors such as Upadacitinib, are encouraging. This report outlines the third reported case of erosive lichen planus to be successfully treated with Upadacitinib in a 70-year-old woman with treatment-resistant disease...
2023: SAGE Open Medical Case Reports
Mohammed Omar Al Salihi, Murali K Iyyani, Sarina Koilpillai, Gerson Quintero, Jorge Parellada, S J Carlan
Multiple endocrine neoplasia 2A is an autosomal dominant disease characterized by medullary thyroid cancer, pheochromocytoma, and primary hyperparathyroidism. Coronary artery disease is associated with the disorder, but the mechanism is unclear. A 27-year-old female presented with chest pain and palpitations. A left heart catheterization was performed and showed 80% stenosis of the left anterior descending artery. Imaging and workup also revealed primary hyperparathyroidism associated with a parathyroid adenoma and elevated serum and urine metanephrines and norepinephrines...
2023: SAGE Open Medical Case Reports
Yusuke Ishida, Shunya Sekiguchi, Yumi Tsuzuki, Aya Kawachi, Mikiko Tomino
In this report, we present a case of a patient with bile peritonitis caused by gallbladder perforation associated with acute cholecystitis, which required intensive postoperative care. The patient was a woman in her 40s who presented with abdominal pain. Upon examination, she was diagnosed as having acute cholecystitis and bile peritonitis caused by gallbladder perforation. Subsequently, a partial cholecystectomy, omental pack, and drainage were performed. Initially, her bile duct enzyme levels improved; however, they subsequently increased again...
2023: SAGE Open Medical Case Reports
Willbroad Kyejo, Fatma Mohamed, Fatma Zahran, Sumayyah Saudin, Antony Ngowi, Juvenalius Anselm, Nancy Matillya, Gloria Gachocha
Renal agenesis refers to the congenital absence or complete failure of development of one or both kidneys. It occurs when the kidneys fail to form during embryonic development. This case report describes the presentation of a 23-year-old male patient who experienced sporadic episodes of abdominal pain on the right side and occasional episodes of hematuria. Diagnostic investigations, including ultrasonography and magnetic resonance imaging scans, confirmed the diagnosis of right renal agenesis. The management of the patient in this case report involved close monitoring of renal function and regular follow-up visits...
2023: SAGE Open Medical Case Reports
Xing-Zhen Liang, Yu-Peng Tang, Ji-Gan Wang
Acute necrotic encephalopathy in children is a very rare complication of severe acute respiratory syndrome coronavirus 2 infection and has rarely been reported worldwide. A 45-day-old girl was admitted to our hospital with fever and listlessness. A nose swab tested positive for the novel coronavirus nucleic acid, and her cerebrospinal fluid was positive for severe acute respiratory syndrome coronavirus 2. An early head magnetic resonance imaging scan indicated multiple abnormal signals in her bilateral cerebral hemispheres, and encephalitis was diagnosed...
2023: SAGE Open Medical Case Reports
Eliana Rohr, Alexandra Laverde-Saad, Hanieh Zargham, May Chergui, Kevin Watters, Alfred Balbul
Cutaneous angiosarcomas are rare soft tissue tumours originating from hematogenous vasculature that are aggressive and carry a poor prognosis. We describe the case of a 73-year-old man with a low-grade well-differentiated angiosarcoma. Our case distinguishes itself from those previously reported in the slow progression and important delay to the presentation of 30 months and survival time of 5.5 years. Additionally, its severe clinical appearance (T2 stage) but milder pathological picture (T1 stage) is very uncommon...
2023: SAGE Open Medical Case Reports
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