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Asia Oceania Journal of Nuclear Medicine & Biology

Rashid Hashmi
This series comprises of a quiz pertaining to the identification of salient and important anatomical structures and landmarks expected to be seen at a given level on the computed tomography (CT) image. The representative image is followed by a series of images showing examples of different commonly encountered pathological entities that can be seen at this level in a routine clinical practice. Readers are encouraged to identify highlighted anatomical structures and landmarks in all the images and appreciate how a given abnormality can alter the appearance of normal structures...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Mahsa Sabour, Ali Shoeibi, Somayeh Ghahremani, Ramin Sadeghi
We reported a 71 years old woman, with history of rest and postural tremor, bradykinesia and memory problems. In her dynamic MRI, a contrast-enhanced tumor in the cerebellopontine (CP) angle was found which was compatible with a meningioma. 99m Tc-TRODAT SPECT showed decreased activity in the left putamen, indicating idiopathic Parkinson disease. There was also a focus of increased activity on the right side of the skull base, which was compatible with meningioma in MRI.
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Shrikant Vasantrao Solav, Shailendra Vasant Savale, Abhijit Mahaveer Patil
FDG PET CT scan is considered to be a sensitive tool to detect skeletal metastasis in known malignancies. However, it's high sensitivity and low specificity may account for false positive diagnosis in cases of trauma, infection, inflammation and other benign conditions. Skeletal hemangioma is one of the common benign conditions which are typically ametabolic on FDG PET CT with no uptake on bone scan. However, rarely they may have atypical imaging features and appear hypermetabolic. Other imaging modalities such as MRI and CT scan have typical imaging findings for hemangioma and can be used for evaluation of focal hypermetabolic skeletal lesions...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Reyhaneh Manafi-Farid, Narjess Ayati, Mohammad Eftekhari, Babak Fallahi, Fardad Masoumi
Colorectal carcinoma is one of the most common causes of cancer-related death, worldwide. Recently, due to the introduction of novel imaging and therapeutic techniques, five-year survival of patients has increased. However, distant metastasis is still expected in half of the patients. Colorectal cancer tends to target the abdominal cavity, liver, lungs, and bones as the common sites of metastasis. Nevertheless, rare cases of muscle metastasis have been reported. This report presents a 23-year-old male, who despite chemotherapy, demonstrated gradual progressive disease and metastases to the submandibular region, lungs, adrenal gland as well as muscles and subcutaneous tissues...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Akanganyira Kasenene, Aju Baidya, Chang-Yin Wang, Hai-Bo Xu
Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic cytokine which controls the differentiation and growth of hematopoietic cells in the bone marrow. We report a severe aplastic anemia (SAA) patient with false-negative 99m Tc sodium phytate bone marrow imaging findings under concurrent G-CSF therapy. The first bone marrow imaging showed a normal bone marrow activity. However, the bone marrow biopsy pathology report revealed a lack of hematopoietic cells. Furthermore, the complete blood count indicated severe pancytopenia resulting in the diagnosis of aplastic anemia (AA)...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Marjan Hashempour, Mahdi Ghorbani, Ernesto Amato, Courtney Knaup
Objectives: The purpose of this research is to study the effect of beta spectrum on absorbed fraction ( ϕ ) and to find suitable analytical functions for beta spectrum absorbed fractions in spherical and ellipsoidal volumes with a uniform distribution for several radionuclides that are commonly used in nuclear medicine. Methods: In order to obtain the beta particle absorbed fraction, Monte Carlo simulations were performed by using the MCNPX code. The validation of the simulations was performed by calculating the absorbed fractions in spheres and comparing the results with the data published by other investigators...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Thet Pe Win, Yoshiyuki Hosokai, Takashi Minagawa, Kenzo Muroi, Kenta Miwa, Ayaka Maruyama, Toshiya Yamaguchi, Kazuto Okano, Khin Moh Moh Htwe, Haruo Saito
Objectives: Alternative normalization methods were proposed to solve the biased information of SPM in the study of neurodegenerative disease. The objective of this study was to determine the most suitable count normalization method for SPM analysis of a neurodegenerative disease based on the results of different count normalization methods applied on a prepared digital phantom similar to one obtained using fluorodeoxyglucose-positron emission tomography (FDG-PET) data of a brain with a known neurodegenerative condition...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Kyohei Okuda, Susumu Fujii, Shota Sakimoto
Objectives: The latest single-photon emission computed tomography (SPECT)/computed tomography (CT) reconstruction system, referred to as xSPECT Bone™, is a context-specific reconstruction system utilizing tissue segmentation information from CT data, which is called a zone map. The aim of this study was to evaluate the effects of zone-map enhancement incorporated into the ordered-subset conjugated gradient minimization (OSCGM) reconstruction method on SPECT images. Methods: Image quality with zone-map enhanced OSCGM (OSCGMz) and non-enhanced OSCGM methods was compared using various reconstruction parameters...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Takashi Kamiya, Tadashi Watabe, Koichi Fujino, Romanov Victor, Yoshiki Kawamura, Kayako Isohashi, Keiko Matsunaga, Mitsuaki Tatsumi, Hiroki Kato, Eku Shimosegawa, Jun Hatazawa
Objectives: Renography is used for the diagnostic evaluation of pediatric patients with a suspected obstruction of urinary tract or impaired renal function. The recommended dose for children have been released by the European Association of Nuclear Medicine, Society of Nuclear Medicine and Molecular Imaging, and Japanese Society of Nuclear Medicine. Since acquisition counts in dynamic scintigraphy are affected by the administered doses and sensitivity of the scintillation camera, the scan procedure should be determined independently...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Atsushi Teramoto, Masakazu Tsujimoto, Takahiro Inoue, Tetsuya Tsukamoto, Kazuyoshi Imaizumi, Hiroshi Toyama, Kuniaki Saito, Hiroshi Fujita
Objectives: Positron emission tomography/computed tomography (PET/CT) examination is commonly used for the evaluation of pulmonary nodules since it provides both anatomical and functional information. However, given the dependence of this evaluation on physician's subjective judgment, the results could be variable. The purpose of this study was to develop an automated scheme for the classification of pulmonary nodules using early and delayed phase PET/CT and conventional CT images. Methods: We analysed 36 early and delayed phase PET/CT images in patients who underwent both PET/CT scan and lung biopsy, following bronchoscopy...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Asra Patel, Shelley Simon, Indirani M Elangoven, Jaykanth Amalchandran, Avani S Jain, Thangalakshmi S
Objectives: To evaluate the role of Tc-99m TRODAT-1 Single Photon Emission Computed Tomography (SPECT) in Parkinson's Disease (PD) by assessing the correlation of clinical disease severity, disease duration and age at onset of disease with specific uptake ratio of Tc-99m TRODAT-1 in striatum. Methods: The study included 63 patients in age range of 40-72 years with clinical diagnosis of PD and nine controls. Clinical history of patients was obtained regarding age at onset of disease and disease duration...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Fuzuki Yano, Masatoshi Itoh, Hisashi Hirakawa, Seiichi Yamamoto, Akira Yoshikawa, Jun Hatazawa
Objectives: To investigate the diagnostic accuracy of positron emission mammography (PEM) and positron emission tomography/computed tomography (PET/CT) for small breast tumors of less than 20 mm in size. Methods: The study was conducted on a total of 100 subjects (i.e., 50 patients with pathologically proven breast cancer and 50 normal cases of medical screening). The total number of tumors was 54 (mean size: 11±5.1 mm, range: 4-20 mm). The diagnostic accuracy of PEM alone, PET/CT alone, and combined PET/CT and PEM was evaluated by two nuclear medicine physicians based on visual inspection...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Akram Al-Ibraheem, Abedallatif AlSharif, Ramiz Abu-Hijlih, Imad Jaradat, Asem Mansour
Objectives: We aim to investigate the clinical impact of 18 F-FDG PET/CT in managing patients with gynecological malignancies and pelvic or extrapelvic lymph nodes that are of equivocal significance on conventional imaging. Methods: We retrospectively evaluated 18 F-FDG PET/CT scans of patients with gynecologic tumors who were referred to King Hussein Cancer Center from January 2010 to August 2014. PET/CT results were compared with MRI and CT findings. We evaluated sensitivity and specificity of 18 F-FDG PET/CT, its role in changing treatment plan and its positive predictive value (PPV) and negative predictive value (NPV)...
2019: Asia Oceania Journal of Nuclear Medicine & Biology
S Rasoul Zakavi
No abstract text is available yet for this article.
2019: Asia Oceania Journal of Nuclear Medicine & Biology
Yuji Tsutsui
No abstract text is available yet for this article.
2018: Asia Oceania Journal of Nuclear Medicine & Biology
Tadaki Nakahara
No abstract text is available yet for this article.
2018: Asia Oceania Journal of Nuclear Medicine & Biology
Batool Al Balooshi, Shabna Miyanath, Amr Elhennawy, Yaser Saeedi, Syed Hammad Tirmazy, Muhammed Muhasin, Bhavna Ray, Mouza Al Sharhan, Hassan Hotait, Yamina Houcinat, Tasnim Keloth
F-18 FDG is the most widely used tracer in molecular imaging and it is applied for many purposes mainly in malignant diseases. Incidental finding are common in FDG-PET/CT imaging and includes benign and malignant lesions. Among the rare tumors‎, adrenal oncocytomas are uncommon findings and incidental findings of thyroid malignancies are not rare. Oncocytoma is a rare adrenocortical tumor and majority of bulky adrenal tumors are benign with uncertain incident of malignancy. In this study, we are reporting a 37-year-old man with two incidental malignancies detected by FDG-PET-CT...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
Patrick Earl A Fernando, Patricia A Bautista
Parathyroid carcinoma is very rare, with only a few documented cases. Hence, metastatic lesions are infrequently documented on scintigraphic imaging. We present a case of a 63-year-old female presenting with elevated serum levels of ionized calcium and parathyroid hormone (PTH) who was referred to our department for a parathyroid scan with SPECT/CT. Parathyroid scintigraphy showed a focus of increased 99m Tc-sestamibi uptake corresponding to a solid mass with calcification in the inferior pole of the right thyroid lobe; tracer retention was noted on delayed images...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
Sara Shakeri, Soroush Zarehparvar Moghadam, Ramin Sadeghi, Narjess Ayati
Sagliker syndrome is a rare form of renal osteodystrophy resulted from untreated secondary hyperparathyroidism. It is described by severe skeletal deformities, high level of PTH in patients with chronic renal failure, and deformed face. This paper reports a 44-year-old male patient with the mentioned characteristics. In addition to the unique clinical features, high levels of ALP and PTH hormones encouraged us to search for syndrome-like a disease, which clinically and paraclinically matched the Sagliker syndrome...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
Raita Araki, Ryosei Nishimura, Anri Inaki, Hiroshi Wakabayashi, Yasuhito Imai, Yoshikazu Kuribayashi, Kenichi Yoshimura, Toshinori Murayama, Seigo Kinuya
Objectives: High-risk neuroblastoma is a childhood cancer with poor prognosis despite modern multimodality therapy. Internal radiotherapy using 131 I-metaiodobenzylguanidine (MIBG) is effective for treating the disease even if it is resistant to chemotherapy. The aim of this study is to evaluate the safety and efficacy of 131 I-MIBG radiotherapy combined with myeloablative high-dose chemotherapy and hematopoietic stem cell transplantation. Methods: Patients with high-risk neuroblastoma will be enrolled in this study...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
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