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Open Access Macedonian Journal of Medical Sciences

https://read.qxmd.com/read/38173466/cytotoxicity-and-antitumor-activity-of-arglabin-and-its-derivatives
#1
JOURNAL ARTICLE
Sergazy Adekenov, Vojtech Spiwok, John Beutler, Olga Maslova, Kairolla Rakhimov
BACKGROUND: At present, more than 8000 sesquiterpene lactones have been isolated and described from natural sources, a significant part of which has cytotoxicity and antitumor activity. One of the practically available sesquiterpene lactones is arglabin, which, as a renewable material, is used for the synthesis of new compounds. The article presents data on the study of cytotoxicity and antitumor activity of the arglabin and its derivatives using molecular modeling methods and, in the experiment in vitro and in vivo ...
2023: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32996903/retraction-five-papers-from-open-access-maced-j-med-sci-vol-7-no-18-2019-sep-30-global-dermatology
#2
Mirko Spiroski
Editor-in-Chief has retracted the following articles from the special issue Vol. 7 No. 18 (2019): Sep 30 (Global Dermatology): (1) DNA Waves and Their Applications in Biology - Massimo Fioranelli et al. - Open Access Macedonian Journal of Medical Sciences (2019) - DOI: 10.3889/oamjms.2019.767; (2) Recovery of Brain in Chick Embryos by Growing Second Heart and Brain - Massimo Fioranelli et al. - Open Access Macedonian Journal of Medical Sciences (2019) - DOI: 10.3889/oamjms.2019.777; (3) A Mathematical Model for the Signal of Death and Emergence of Mind Out of Brain in Izhikevich Neuron Model - Massimo Fioranelli et al...
September 30, 2020: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215108/torsion-of-ileum-due-to-giant-meckel-s-diverticulum-a-case-report
#3
JOURNAL ARTICLE
Nguyen Duy Hung, Trinh Anh Tuan, Than Van Sy, Vu Duc Thinh, Vo Truong Nhu Ngoc, Vu Thi Nga, Van Thai Than
BACKGROUND: Meckel's diverticulum (MD) is detected in approximately 2% of all individuals and only 2-4% MD patients may develop symptoms. Small intestinal obstruction is a frequent complication in adults. CASE REPORT: A 48-year-old male was admitted to emergency department for high intestinal obstruction symptoms. The imaging examinations were failed to detect the underlying causes. A median laparotomy revealed small bowel obstruction (SBO) due to a segment of ileum twisted around a giant MD axis...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215107/preimplantation-genetic-testing-of-aneuploidy-by-next-generation-sequencing-association-of-maternal-age-and-chromosomal-abnormalities-of-blastocyst
#4
JOURNAL ARTICLE
Tien-Truong Dang, Thi-Mui Phung, Hoang Le, Thi-Bich-Van Nguyen, Thi-Sim Nguyen, Thi-Lien-Huong Nguyen, Vu Thi Nga, Dinh-Toi Chu, Van-Luong Hoang, Duy-Bac Nguyen
BACKGROUND: Aneuploidy is a major cause of miscarriages and implantation failure. Preimplantation genetic testing for aneuploidy (PGT-A) by Next Generation Sequencing (NGS) is able to detect of the numeral and structural chromosomal abnormalities of embryos in vitro fertilization (IVF). AIM: This study was aimed to assess the relationship between maternal age and chromosomal abnormalities NGS technology. METHODS: A group of 603 human trophectoderm (TE) biopsied samples were tested by Veriseq kit of Illumina...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215106/neuromuscular-blockade-agents-reversal-with-sugammadex-compared-to-neostigmine-in-the-living-kidney-donors
#5
JOURNAL ARTICLE
Thuy Luu Quang, Huyen Nguyen Thi Thu, Kinh Nguyen Quoc, Ha Nguyen Thu, Dong Pham Van, Nguyen Le Bao Tien, Vo Van Thanh, Vu Thi Nga, Chu Dinh Toi
BACKROUND: The reversation of NMBA (neuromuscular blocking agents) prevents numerous postoperative complications, increases quality of recovery and decreases the time, expenditure spending in hospital. The choice of medicine used to reverse NMBA depends considered as a key fators to gain the best outcome and to avoid the side effects. AIM: To evaluate the postoperative effect on muscle relaxation reversal and side effects of sugammadex 2 mg/kg versus the combination of neostigmine and atropine sulfate in the living kidney donors...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215105/risk-factors-for-stroke-associated-pneumonia
#6
JOURNAL ARTICLE
Do Quyet, Nguyen Minh Hien, Mai Xuan Khan, Pham Dinh Dai, Do Duc Thuan, Dang Minh Duc, Nguyen Dang Hai, Bui Van Nam, Pham Quoc Huy, Mai Duy Ton, Dang Tien Truong, Vu Thi Nga, Dang Phuc Duc
BACKGROUND: Stroke patients are at high risk for stroke-associated pneumonia (SAP). If patients suffer from pneumonia their prognosis will worsen. AIM: To identify factors that increases the risk of SAP in stroke patients. METHODS: A group of 508 patients hospitalized within 5 days after the onset of stroke were enrolled prospectively. RESULTS: The incidence of SAP was 13.4%. Some major risk factors for SAP are: mechanical ventilation (MV) had odds ratio (OR) 16...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215104/the-role-of-serial-nt-probnp-level-in-prognosis-and-follow-up-treatment-of-acute-heart-failure-after-coronary-artery-bypass-graft-surgery
#7
JOURNAL ARTICLE
Bui Duc Thanh, Nguyen Hong Son, Dinh Cong Pho, Nguyen Duy Bac, Vu Thi Nga, Quan Anh Dung, Do Duc Anh, Do Dieu Linh, Hoang Thi Bich Viet, Bui Dang The Anh, Ha The Tan, Pham Ngoc Hung
BACKGROUND: After coronary artery bypass graft (CABG) surgery, heart failure is still major problem. The valuable marker for it is needed. AIM: Evaluating the role of serial NT-proBNP level in prognosis and follow-up treatment of acute heart failure after CABG surgery. METHODS: The prospective, analytic study evaluated 107 patients undergoing CABG surgery at Ho Chi Minh Heart Institute from October 2012 to June 2014. Collecting data was done at pre- and post-operative days with measuring NT-proBNP levels on the day before operation, 2 hours after surgery, every next 24 h until the 5th day, and in case of acute heart failure occurred after surgery...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215103/antibiotic-resistance-profile-and-methicillin-resistant-encoding-genes-of-staphylococcus-aureus-strains-isolated-from-bloodstream-infection-patients-in-northern-vietnam
#8
JOURNAL ARTICLE
Le Van Nam, Do Quyet, Pham Ngoc Hung, Tran Viet Tien, Kieu Chi Thanh, Quan Anh Dung, Do Dieu Linh, Ha The Tan, Nguyen Duy Bac, Thien Chu Dinh, Dinh Cong Pho
BACKGROUND: Evaluating the antibiotic susceptibility and resistance genes is essential in the clinical management of bloodstream infections (BSIs). Nevertheless, there are still limited studies in Northern Vietnam. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). AIM: This study aimed to determine the antibiotic resistance profile and methicillin-resistant encoding genes of Staphylococcus aureus (S...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215102/autologous-transplantation-of-adipose-derived-stem-cells-to-treat-acute-spinal-cord-injury-evaluation-of-clinical-signs-mental-signs-and-quality-of-life
#9
JOURNAL ARTICLE
Nguyen Le Bao Tien, Nguyen Dinh Hoa, Vo Van Thanh, Nguyen Van Thach, Vo Truong Nhu Ngoc, Thien Chu Dinh, Thuy Nguyen Thi Phuong, Phung Lam Toi, Dinh Toi Chu
BACKGROUD: Spinal cord injury (SCI) is damage that can cause a temporary or permanent change in spinal cord functions. AIM: This work evaluates clinical signs, mental signs, and quality of life (QoL) after autologous adipose-derived stem cells (ADSCs) transplantation to treat acute spinal cord injury (SCI). METHODS: In this study, 47 SCI patients were recruited and divided into two groups: intervention and control. ADSCs were isolated and cultured under the cell culture quality control procedure...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215101/antibiotic-resistance-profile-and-diversity-of-subtypes-genes-in-escherichia-coli-causing-bloodstream-infection-in-northern-vietnam
#10
JOURNAL ARTICLE
Pham Ngoc Hung, Do Quyet, Kieu Chi Thanh, Dinh Cong Pho, Tran Viet Tien, Quan Anh Dung, Do Dieu Linh, Ha The Tan, Thien Chu Dinh, Nguyen Duy Bac, Le Van Nam
BACKGROUND: Evaluating the antibiotic susceptibility and resistance genes is essential in the clinical management of bloodstream infections (BSIs). But there are still limited studies in Northern Vietnam. AIM: The aim of the study was to determine the antibiotic resistance profile and characteristics of subtypes genes in Escherichia coli causing BSIs in Northern Vietnam. METHODS: The cross-sectional study was done in the period from December 2012 to June 2014 in two tertiary hospitals in Northern Vietnam...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215100/lung-volume-reduction-surgery-in-patients-with-heterogenous-emphysema-selecting-perspective
#11
JOURNAL ARTICLE
Nguyen Truong Giang, Trung Nguyen Ngoc, Nguyen Van Nam, Nguyen Viet Nhung, Ta Ba Thang, Dong Khac Hung, Nguyen Duy Bac, Chu Dinh Toi, Pham Ngoc Hung
BACKGROUND: Lung volume reduction surgery (LVRS) was introduced to alleviate clinical conditions in selected patients with heterogenous emphysema. Clarifying the most suitable patients for LVRS remained unclear. AIM: This study was undertaken to specifically analyze the preoperative factor affecting to LVRS. METHODS: The prospective study was conducted at 103 Military Hospital between July 2014 and April 2016. Severe heterogenous emphysema patients were selected to participate in the study...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215099/short-tandem-repeats-used-in-preimplantation-genetic-testing-of-%C3%AE-thalassemia-genetic-polymorphisms-for-15-linked-loci-in-the-vietnamese-population
#12
JOURNAL ARTICLE
Dang Tien Truong, Ngo Van Nhat Minh, Dinh Phuong Nhung, Hoang Van Luong, Do Quyet, Tran Ngoc Anh, Trinh The Son, Nguyen Thanh Tung, Nguyen Thi Thu Ha, Duong Thi Phuong Anh, Le Hoang, Nguyen Le Thuy, Nguyen Thi Hoa, Nguyen Duy Bac, Vu Thi Nga, Toi Chu Dinh
BACKGROUND: β-thalassemia is one of the most common monogenic diseases worldwide. Preimplantation genetic testing (PGT) of β-thalassemia is performed to avoid affected pregnancies has become increasingly popular worldwide. In which, the indirect analysis using short tandem repeat (STRs) linking with HBB gene to detect different β-globin (HBB) gene mutation is a simple, accurate, economical and also provides additional control of contamination and allele-drop-out ADO. AIM: This study established microsatellite markers for PGT of Vietnamese β-thalassemia patient...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215098/treatment-of-anti-nmda-receptor-encephalitis-with-ovarian-teratoma-removal-a-literature-review-and-two-case-reports
#13
JOURNAL ARTICLE
Nguyen Phuong Tu, Pham Ba Nha, Nguyen Duy Hung, Nguyen Hoang Minh, Hoang Ngoc Anh, Thien Chu Dinh
BACKGROUND: N-methyl-d-aspartate receptor (NMDAR) antibody encephalitis appears common in the world, but the number of clinical cases in Vietnam which were recorded is rare. CASE REPORT: We describe two new cases of disease in recent years with the aim of contributing to diagnosis and treatment experiences. These cases were noted over the past 3 years with the patients who have been treated at lower levels but have no results. They came to us when symptoms became worse and therefore required prolonged treatment with special intensive care facilities...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215097/transformation-chlorophyll-a-of-spirulina-platensis-to-chlorin-e6-derivatives-and-several-applications
#14
JOURNAL ARTICLE
Hoa Thi Hai Bui, Tam Thi Pham, Hien Thi Thu Nguyen, Trung Minh Do, Vu Thi Nga, Nguyen Duy Bac, Vu Thi Bich Huyen, Hai Minh Le, Quang Canh Tran
BACKGROUND: Spirulina platensis contains a large amount of chlorophylls, chlorophyll a, that are starting materials to synthesize functionalized chlorins. Chlorin e6 (Ce6) as well as its derivatives are second generation sensitizers using in photodynamic therapy (PDT) of various cancers. In this study, we transfer chlorophyll a of S. platensis to Ce6 derivatives and determine their several applications. AIM: We aimed to evaluate the effects of Ce6 derivatives to treat cancer cells...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215096/a-rare-colonic-metastasis-case-from-hepatocellular-carcinoma
#15
JOURNAL ARTICLE
Binh Van Pham, Huynh Huu Phan, Lam Le Ngo, Hang Thi Thuy Nguyen, Ky Van Le, Thien Chu Dinh, Nguyen Duy Bac
BACKGROUND: Hepatocellularcarcinoma (HCC) metastasis include intrahepatic and extrahepatic metastasis. Similar to intrahepatic metastasis, extrahepatic metastases are not unusual in cases with HCC. However, colonic metastasis is infrequent. CASE REPORT: We describe a clinical case, he was diagnosed with HCC a year ago, treated with TACE (transarterialchemoembolisation), re-examined with abdominal pain and defecation disorder. The tests such as CT scan, colorectal endoscopy, fine needle aspiration (FNA) revealed secondary metastatic lesion of HCC in sigmoid colon...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215095/anatomical-study-of-femoral-condylar-index-in-magnetic-resonance-imaging-implication-to-total-knee-replacement-surgery-for-vietnamese-people
#16
JOURNAL ARTICLE
Dung Tran Trung, Phuong Nguyen Huy, Tung Pham Son, Thien Chu Dinh, Toi Chu Dinh
BACKGROUND: The femoral rotation angle is important element in total knee replacement (TKR). AIM: To measure this angle, we determine through the axes: the transepicondylar axis (cTEA and sTEA), the posterior condylar axis (PCA), the anteroposterior axis (APA - Whiteside axis). METHODS: Measuring the angles created by the four axes: cTEA, sTEA, PCA and APA in magnetic resonance imaging (MRI); determining the femoral rotation angle and application TKR...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215094/the-anatomical-numerical-measurement-of-posterior-cruciate-ligament-a-vietnamese-cadaveric-study
#17
JOURNAL ARTICLE
Do Van Minh, Tran Trung Dung, Ngo Van Toan, Nguyen Huy Phuong, Vo Sy Quyen Nang, Thien Chu Dinh
BACKGROUND: The posterior cruciate ligament (PCL) is crucial to restrain the posterior translation of the tibia. Its anatomical structure is complex. A proper understanding of PCL anatomy may assist surgeon in reconstructing anatomically native PCL. AIM: To describe the anatomical numerical measurement of the PCL in Vietnamese adults. METHODS: Twenty-one fresh cadaveric knees were examined. The macroscopic details of the intra-articular PCL, the attachment of the anterolateral bundle (ALB), posteromedial bundles (PMB) to the femur and tibia were analysed...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215093/preliminary-result-of-arthroscopic-anterior-cruciate-ligament-reconstruction-using-anterior-half-of-peroneus-longus-tendon-autograft
#18
JOURNAL ARTICLE
Dung Tran Trung, Son Le Manh, Luan Nguyen Thanh, Thien Chu Dinh, Toi Chu Dinh
BACKGROUND: Arthroscopic anterior cruciate ligament reconstruction is one of the most successful operations in sports medicine. At present, ligament autografts have been the best method due to good histocompatibility, rapid healing, no cross-contamination, and low cost of treatment. However, autografts do not have infinite amount and are also not always feasible. Anterior half of peroneus longus tenden autograft is likely to become a source of autograft with many advantages. This study aims to evaluate the clinical outcomes of arthroscopic anterior cruciate ligament reconstruction using anterior half of peroneus longus tendon autograft (AHPLT)...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215092/-false-patellar-duplication-originated-from-synovial-osteochondromatosis-in-knee-joint-a-rare-case-report
#19
JOURNAL ARTICLE
Dung Tran Trung, Tung Pham Son, Thien Chu Dinh, Toi Chu Dinh
BACKGROUND: "False patellar duplication" is a situation where there are two pieces in the position of a knee-joint like patella. It can derive from cartilage tumors, soft tissue tumors, or gout tumors, or due to the heterotopic ossification, forming a sub patella in the knee joint. CASE REPORT: A woman, 57 years old, healthy history, she has hospitalized for right knee joint pain since 2 years. Diagnosis: the synovial osteochondromatosis of the right knee...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/32215091/primary-cementless-bipolar-long-stem-hemiarthroplasty-for-unstable-osteoporotic-intertrochanteric-fracture-in-the-elderly-patients
#20
JOURNAL ARTICLE
Tran Trung Dung, Nguyen Dinh Hieu, Le Manh Son, Thien Chu Dinh, Toi Chu Dinh
BACKGROUND: Intertrochanteric fracture (ITF) is a major part of fracture in femoral head fracture. 95% of ITF are found in elderly patients. Osteosynthese is the preferred method of choice. However, elderly patients had osteoporotic, combined with many of chronic disease conditions that increase the rate of osteosynthese failure. Hemiarthroplasty bipolar long-stem is a surgical method that helps patients relieve pain, facilitate early rehabilitation, limit long-term complications, and improve quality of life for patients...
December 30, 2019: Open Access Macedonian Journal of Medical Sciences
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