International Journal of Reproductive Biomedicine (Yazd, Iran)

BACKGROUND: The benefits of frozen embryo transfer (FET) vs. fresh embryo transfer for in vitro fertilization (IVF) have been discussed in previous studies. OBJECTIVE: To determine and compare the pregnancy outcomes following FET and frozen embryo transfer in women who underwent assisted reproductive techniques. MATERIALS AND METHODS: In this cross-sectional study, 233 women candidates for IVF/intra cytoplasmic sperm injection who referred to the Kamali Training Medical Center, Karaj, Iran during 2019-2020 were evaluated in 2 groups of fresh (n = 127) and frozen (n = 106) embryo transfers...

BACKGROUND: Approximately two-thirds of infant mortality within the first year of life are caused by preterm labor (PL). OBJECTIVE: This study aimed to investigate the effects of progesterone-based compounds to prevent PL. MATERIALS AND METHODS: This randomized clinical trial study was conducted on 146 pregnant women admitted to Department of Obstetrics and Gynecology, Afzalipour hospital in Kerman University of Medical Sciences, Kerman, Iran in June 2019...

BACKGROUND: Varicocele is characterized by abnormal dilation of the testicular vein, which results in hypoxia, the accumulation of reactive oxygen species, and the production of proinflammatory cytokines. It seems that a group of cytosolic receptors named nod-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome, is activated and involved in the pathogenesis of varicocele. OBJECTIVE: We aim to determine the time course of NLRP3 inflammasome expression in the testis tissue following varicocele induction...

BACKGROUND: Polycystic ovary syndrome (PCOS) is a heterogeneous medical condition with a cluster of metabolic and endocrine disorders including dyslipidemia, insulin resistance, and hyperandrogenism. OBJECTIVE: The present study aimed to determine the effects of single-dose and co-supplementation of vitamin D (vit D) and omega-3 (O3) on anthropometric and several biochemical factors in women with PCOS. MATERIALS AND METHODS: In this double-blind, randomized clinical trial, 80 PCOS women referred to Shahid Motahhari Clinic, Shiraz, Iran, from April to October 2017 were studied in 4 groups (n = 20/each) for 8 wk...

[This corrects the article on p. 699 in vol. 14 PMCPMC5153575.].

BACKGROUND: In some societies, childbearing is a part of women's identity and infertile women are under a great amount of pressure from others. OBJECTIVE: This study aims to evaluate the relationship between infertility factors and sexual functioning, perceived social support, and adherence to treatment in infertile women. MATERIALS AND METHODS: In this cross-sectional study, 230 infertile women who referred to the infertility center of Shahrekord, Iran in 2022 were enrolled...

BACKGROUND: Ovarian hyperstimulation syndrome (OHSS) is a serious life-threatening complication of infertility treatment. Vulvar edema is a disease with various causes and frequent phenomena seen in physiological and pathologic conditions like pregnancy, inflammatory disorders, tumors, idiopathic reasons, and most importantly, in the severe form of OHSS. CASE PRESENTATION: Here, we report a 26-yr-old woman with severe OHSS, recombinant follicle-stimulating hormone therapy...

BACKGROUND: Recurrent miscarriage is one of the most prevalent reproductive diseases. This phenomenon has several reasons, including maternal, hormonal, immunological, and parental genetic factors. Idiopathic recurrent miscarriage (IRM), with no distinctive etiology, involves about half of the recurrent miscarriage cases. Some mutations in mitochondrial DNA can lead to miscarriage. Mitochondrial tRNA (mt-tRNA) mutations cause nearly half of the mitochondrial disorders. OBJECTIVE: To identify mt- tRNA <mml:math xmlns:mml="https://www...

BACKGROUND: Sexually transmitted infections (STIs) are one of the world's most severe health challenges. The existence of STIs such as human papillomavirus (HPV) might cause cervical cell changes leading to cervical cancer. OBJECTIVE: This study aims to assess the association of STIs with cervical cytological abnormalities and genital warts among women in northeastern Iran. MATERIALS AND METHODS: This cross-sectional study was carried out on 190 women referred to the central laboratory of Academic Center for Education, Culture, and Research, Mashhad, Iran from March to July 2022...

BACKGROUND: Given the significant changes in family formation through donation procedures, providing an optimal level of care that is responsive to the needs of mothers who get pregnant via oocyte donation is pivotal to improve their maternal role. Therefore, it is necessary to recognize the needs of oocyte donation mothers to address their specific needs. OBJECTIVE: This study aimed to review the needs of women in their journey towards motherhood via oocyte donation...

BACKGROUND: Zinc oxide nanoparticles (ZnO-NPS) are widely used inhuman life; however, they do have side effects on human health. OBJECTIVE: This study aimed to evaluatethedifferent doses of ZnO-NPS on testicular tissue. MATERIALS AND METHODS: 35 male Wistar rats(10-12 wk, 220 <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:mo>±</mml:mo></mml:math> 20gr) were divided into 7 groups of 5, including the control group (gavaged distilled water daily), sham group (received intraperitoneal doses of distilled water twice a week)...

BACKGROUND: Endometriosis is a challenging gynecological disease and a debilitating condition that profoundly affects the individual's quality of life. Besides pathological confirmation, diagnostic laparoscopy has been internationally accepted as the standard method to identify the accurate mapping of endometriosis. Transvaginal sonography (TVS) is the first non-invasive imaging modality to estimate the severity of endometriosis. OBJECTIVE: This study aimed to evaluate the accuracy of TVS in affected women compared with surgical findings...

BACKGROUND: Endometriosis is a disease that affects women throughout their sexual life. Sexual health is, therefore, a major concern for these women. OBJECTIVE: This study aimed to assess the effects of the sensate focus technique and position changing on the sexual function of women with deep-infiltrating endometriosis 3-6 months after surgery. MATERIALS AND METHODS: This clinical trial study was performed on 80 women with deep endometriosis, aged 18-45 yr, who were referred to the endometriosis clinic of Avicenna fertility center, Tehran, Iran for follow-up after surgery from January to September 2021...

BACKGROUND: Selecting a suitable and preferable method for endometrial preparation in frozen embryo transfer (FET) cycles for women with adenomyosis is still challenging in infertility treatment. OBJECTIVE: To compare 2 artificial endometrial preparation regimens with and without gonadotropin-releasing hormone agonist (GnRHa) pretreatment in women with adenomyosis undergoing FET cycles. MATERIALS AND METHODS: This randomized clinical trial study was conducted on 140 adenomyosis cases who underwent FET cycles at Arash Women's hospital, Tehran, Iran from May 2020 to March 2021...

No abstract text is available yet for this article.

BACKGROUND: In 15% of all clinical pregnancies, a miscarriage can occur, but the exact cause of this phenomenon is not fully understood. However, it is believed that a faulty placenta, which triggers an inflammatory response in the mother's body, may be one of the causes. Medical literature has increasingly focused on 2 indicators of inflammation, the platelet-lymphocyte ratio (PLR) and neutrophil-lymphocyte ratio (NLR). Despite this, there has yet to be a study conducted that examines the rates of PLR and NLR in cases of miscarriage...

BACKGROUND: Advances in cell culture media have led to a trend of embryo transfer from the early cleavage stages to blastocyst stage. OBJECTIVE: The study aims to compare the effects of fresh embryo transfer in cleavage and blastocyst stage on pregnancy outcomes. MATERIALS AND METHODS: This cross-sectional study was conducted on 1422 cases referred to the Umm-al-Banin Infertility Clinic Center, Dezful, Iran, between July 2013 and December 2020 who were candidates for in vitro fertilization/intracytoplasmic sperm injection for fresh embryo transfer...

BACKGROUND: Ovarian tissue extract (OTE) and sodium selenite (SS) enhance the growth and maturation of preantral follicles in a dose-dependent manner. OBJECTIVE: The present study was designed to bring more information regarding the mechanism of OTE and SS on the mRNA expression of follicle-stimulating hormone receptors (FSHR) and the proliferation cell nuclear antigens (PCNA) of in vitro matured isolated follicles. MATERIALS AND METHODS: The tissue extract was prepared from adult ovaries...

BACKGROUND: Ectopic pregnancy (EP) is the implantation of a fertilized egg outside the uterine cavity or in an unusual location. According to the clinical case reports, hormonal contraceptive failures may be related to emergency contraceptives and EP. EP may be treated medically, surgically, or expectantly. Currently, there is no consensus regarding whether a multiple- or double-dose regimen with methotrexate (MTX) or an additional dose could be more effective than a single-dose regimen...

BACKGROUND: Preterm labor is one of the main causes of neonatal mortality and its treatment is still challenging. OBJECTIVE: The study aimed to compare the effectiveness of nifedipine (Nif) with and without sildenafil citrate (SC) for the treatment of preterm labor in pregnant women. MATERIALS AND METHODS: In this clinical trial study, 126 pregnant women referred to the Fatemieh hospital, Hamadan, Iran with a complaint of preterm labor were evaluated...